Cell traction forces (CTFs) are the forces produced by cells and exerted on extracellular matrix or an underlying substrate. CTFs function to maintain cell shape, enable cell migration, and generate and detect mechanical signals. As such, they play a...
Increasing attention is devoted to the use of nanomechanics as a marker of various pathologies. Atomic force microscopy (AFM) is one of the techniques that could be applied to quantify the nanomechanical properties of living cells with a high spatial...
Cell migration is a key contributor to wound repair. This study presents findings indicating that the liquid crystal based cell traction force transducer (LCTFT) system can be used in conjunction with a bespoke cell traction force mapping (CTFM) soft...
Cells constantly experience mechanical forces during growth and development. Increasing evidence suggests that mechanical forces can regulate cellular processes such as proliferation, migration, and differentiation. Therefore, developing new tools to...
It is an understatement that mating and DNA transfer are key events for living organisms. Among the traits needed to facilitate mating, cell adhesion between gametes is a universal requirement. Thus, there should be specific properties for the adhesi...
One of the most successful applications of atomic force microscopy (AFM) in biology involves monitoring the effect of force on single biological molecules, often referred to as force spectroscopy. Such studies generally entail the application of pull...
Robotic endoscopic systems offer intuitive remote manipulation and reduce radiation exposure; however, the lack of axial force sensing remains an important limitation for monitoring interactions during insertion. To address this issue, we developed E...
This paper presents a novel method to measure clamping force by using the vibration of bolts. The resonance frequency of the bolt increases in line with the clamping force during the tightening process. These characteristics were measured and utilize...
Bacterial contact leaching of ores is more effective than non-contact leaching. Adhesion is the first step for leaching bacteria to form a biofilm on a mineral surface. Extracellular polymeric substances (EPS) are pivotal for mediating bacterial adhe...
Cells of two molecular genetic types of breast cancer—hormone-dependent breast cancer (ZR-75 cell line) and triple-negative breast cancer (BT-20 cell line)—were studied using atomic force microscopy and an optical nanomotion detection met...
Contact-rich precision assembly fails in ways visible in the force/torque and proprioceptive streams before they are visible in the finished part, which makes online quality monitoring attractive. We ask whether monitoring accuracy or the recovery po...
Atomic force microscopy (AFM) combined with fluorescence microscopy has been used to quantify cytomechanical modifications induced by resveratrol (at a fixed concentration of 50 µM) in a breast cancer cell line (MCF-7) upon temporal variation....
The replacement of the cantilever tip by a living cell in Atomic Force Microscopy (AFM) experiments permits the direct quantification of cell–substrate and cell–cell adhesion forces. This single-cell probe force measurement technique, whe...
Wearable robots require compact sensing interfaces to monitor the forces transmitted through attachment straps. This study aims to combine strap fastening and force measurement in a lightweight buckle, enabling the magnitude and direction of strap lo...
On-time monitoring and condition assessments of steel cables provide mission-critical data for informed decision making, ensuring the structural safety of post-tensioned concrete structures. This study aimed to develop a spiral deployment scheme of d...
This paper presents a measurement system intended to monitor the usage of walker assistive devices. The goal is to guide the user in the correct use of the device in order to prevent risky situations and maximize comfort. Two risk indicators are defi...
The free cantilever method (FCM) is a bridge construction method in which the left and right segments are joined in sequence from a pier without using a bottom strut. To support the imbalance of the left and right moments during construction, tempora...
The success of cell therapy approaches is greatly dependent on the ability to precisely deliver and monitor transplanted stem cell grafts at treated sites. Iron oxide particles, traditionally used in vivo for magnetic resonance imaging (MRI), have be...
Leash tension forces exerted by dog and handler during walks affect their welfare. We developed a novel ambulatory measurement device using a load cell and a tri-axial accelerometer to record both the tension and direction of forces exerted on the le...
A crank press is converted into a smart fatigue testing machine for 3-point bending of polymer matrix composite specimens. The press is retrofitted with a load cell base for work holding, which monitors the bending force applied by the ram, a cycle c...
Magnetoelastic sensors, which undergo mechanical resonance when interrogated with magnetic fields, can be functionalized to measure various physical quantities and chemical/biological analytes by tracking their resonance behaviors. The unique wireles...
Magnetic nanoparticles (MNPs) are widely known as valuable agents for biomedical applications. Recently, MNPs were further suggested to be used for a remote and non-invasive manipulation, where their spatial redistribution or force response in a magn...
Atomic force microscopy (AFM) has emerged as a powerful platform for quantifying nanoscale mechanical properties of cells, tissues, and extracellular matrix (ECM) components, providing candidate biomarkers for disease diagnosis, classification, progn...
The plant cell mechanics, including turgor pressure and wall mechanical properties, not only determine the growth of plant cells, but also reflect the functional and structural changes of plant cells under biotic and abiotic stresses. However, there...
Prestressed Concrete Wire and Strand (PC) strands are the most used materials to introduce prestress in a Pre-Stressed Concrete (PSC) structure. However, it is difficult to evaluate the final prestress force of the PC strand after prestressing or its...
Lithium-ion batteries (LIBs) in electric vehicle battery packs are assembled under mechanical constraints that exert compression force during operation. During operation, battery cells undergo volumetric changes that cause thickness variations, known...
This study investigates the simulation of interactions between cells and antibacterial nanostructured surfaces. Understanding the physical interaction forces between cells and nanostructured surfaces is crucial for developing antibacterial materials,...
There is a group of measurement techniques that can be used in the task of force identification in steel bolts. In this paper, the potential of elastic wave propagation signals was studied for possible application in force monitoring systems. A serie...
The electrochemical cell is designed with a conductive substrate (working electrode) where deposition takes place within a three-electrode cell. In order to complete the electrochemical circuit, the cell has been equipped with a counter electrode (CE...
Lithium-ion batteries are being implemented in different large-scale applications, including aerospace and electric vehicles. For these utilizations, it is essential to improve battery cells with a great life cycle because a battery substitute is cos...
Flow perfusion bioreactors have been extensively investigated as a promising culture method for bone tissue engineering, due to improved nutrient delivery and shear force-mediated osteoblastic differentiation. However, a major drawback impeding the t...
Transforming growth factor β1 (TGF-β1) is critical to cell differentiation, proliferation, and apoptosis. It is important to understand the binding affinity between TGF-β1 and its receptors. In this study, their binding force was measu...
Greenhouse cultivation has gained a special importance in recent years and become the basis of the economy in south-eastern Spain. The structures used are light and, due to weather events, often collapse completely or partially, which has generated i...
The actual grip force provided by a hand prosthesis is an important parameter to evaluate its efficiency. To this end, a split cylindrical handlebar embedding a single-axis load cell was designed, 3D printed and assembled. Various measurements were m...
This work introduces a neuromorphic sensor (NS) based on force-sensing resistors (FSR) and spiking neurons for robotic systems. The proposed sensor integrates the FSR in the schematic of the spiking neuron in order to make the sensor generate spikes...
Monitoring biomechanics of cells or tissue biopsies employing atomic force microscopy (AFM) offers great potential to identify diagnostic biomarkers for diseases, such as colorectal cancer (CRC). Data on the mechanical properties of CRC cells, howeve...
The development of cell-based biomaterial alternatives holds significant promise in tissue engineering applications, but it requires accurate mechanical assessment. Herein, we present the development of a novel 3D-printed confined compression apparat...
The major challenge of the cell cycle is to deliver an intact, and fully duplicated, genetic material to the daughter cells. To this end, progression of DNA synthesis is monitored by a feedback mechanism known as replication checkpoint that is untime...
As cancer mortality rates rise globally, malignancies have become the second leading cause of death. Recently, efforts have been made to understand the impact of the tumor microenvironment that involves fluid shear forces. Biomechanical stimulation,...
This study proposes an indirect approach that estimates roll force from motor current signals in a rolling mill. Motor current is first converted to motor torque using an induction-motor equivalent-circuit model, then to roll torque via the gear rati...
This work investigates the role of preload pressure in governing the electro-chemo-mechanical (ECM) behavior of lithium iron phosphate (LFP)/graphite pouch cells during calendar aging. Cells aged at 60 °C under different preload levels were syste...
A great breadth of questions remains in cellular biology. Some questions cannot be answered using traditional analytical techniques and so demand the development of new tools for research. In the near future, the development of highly integrated micr...
Culture platform surface topography plays an important role in the regulation of biological cell behaviour. Understanding the mechanisms behind the roles of surface topography in cell response are central to many developments in a Lab on a Chip, medi...
We investigated the immediate molecular consequences of traumatic brain injuries (TBIs) using a novel proteomics approach. We simulated TBIs using an innovative laboratory apparatus that employed a 5.1 kg dummy head that held neuronal cells and gener...
Humanoid robots operating near humans require short protective reaction times in physical human–robot interaction (pHRI). Safety standards distinguish between quasi-static and transient contact. This paper quantifies the reaction timing of a co...
Despite the attractive merits of high-capacity strands, the application in bridge girders is limited due to concerns, including concrete cracking, excessive stress, and cambers. An efficient and defect-free production is the first step to wide applic...
Fibroblast cell migration plays a crucial role in the wound-healing process. Hence, its quantitative investigation is important to understand the mechanism of the wound-healing process. The dynamic nature of the wound-healing process can be easily im...
Since blood flow is a physiologically important parameter in determining the state of the tissue (e.g., viability and activity), various blood flow measurement techniques have been developed. However, existing blood flow measurement methods require c...
We report a paper-based self-powered sensor patch for prevention and management of exercise-induced hypoglycemia. The article describes the fabrication, in vitro, and in vivo characterization of the sensor for glucose monitoring in human sweat. This...
Low back pain is a major cause of disability worldwide, often associated with deficits in trunk extensor strength control. Accurate assessment of trunk extension strength control is crucial for diagnosing impairments and monitoring interventions. Thi...
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