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Article

A Single-Use, Self-Powered, Paper-Based Sensor Patch for Detection of Exercise-Induced Hypoglycemia

Bioelectronics & Microsystems Laboratory, Department of Electrical & Computer Engineering, State University of New York-Binghamton, Binghamton, NY 13902, USA
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Author to whom correspondence should be addressed.
Micromachines 2017, 8(9), 265; https://doi.org/10.3390/mi8090265
Received: 27 July 2017 / Revised: 23 August 2017 / Accepted: 27 August 2017 / Published: 31 August 2017
(This article belongs to the Special Issue Paper-Based Transducers and Electronics)
We report a paper-based self-powered sensor patch for prevention and management of exercise-induced hypoglycemia. The article describes the fabrication, in vitro, and in vivo characterization of the sensor for glucose monitoring in human sweat. This wearable, non-invasive, single-use biosensor integrates a vertically stacked, paper-based glucose/oxygen enzymatic fuel cell into a standard Band-Aid adhesive patch. The paper-based device attaches directly to skin, wicks sweat by using capillary forces to a reservoir where chemical energy is converted to electrical energy, and monitors glucose without external power and sophisticated readout instruments. The device utilizes (1) a 3-D paper-based fuel cell configuration, (2) an electrically conducting microfluidic reservoir for a high anode surface area and efficient mass transfer, and (3) a direct electron transfer between glucose oxidase and anodes for enhanced electron discharge properties. The developed sensor shows a high linearity of current at 0.02–1.0 mg/mL glucose centration (R2 = 0.989) with a high sensitivity of 1.35 µA/mM. View Full-Text
Keywords: sweat sensor patch; self-powered glucose sensor; enzymatic fuel cell; paper-based device; exercise-induced hypoglycemia sweat sensor patch; self-powered glucose sensor; enzymatic fuel cell; paper-based device; exercise-induced hypoglycemia
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MDPI and ACS Style

Cho, E.; Mohammadifar, M.; Choi, S. A Single-Use, Self-Powered, Paper-Based Sensor Patch for Detection of Exercise-Induced Hypoglycemia. Micromachines 2017, 8, 265. https://doi.org/10.3390/mi8090265

AMA Style

Cho E, Mohammadifar M, Choi S. A Single-Use, Self-Powered, Paper-Based Sensor Patch for Detection of Exercise-Induced Hypoglycemia. Micromachines. 2017; 8(9):265. https://doi.org/10.3390/mi8090265

Chicago/Turabian Style

Cho, Eunyoung; Mohammadifar, Maedeh; Choi, Seokheun. 2017. "A Single-Use, Self-Powered, Paper-Based Sensor Patch for Detection of Exercise-Induced Hypoglycemia" Micromachines 8, no. 9: 265. https://doi.org/10.3390/mi8090265

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Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

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