Next Article in Journal
Visualization Study of Oil-in-Water-in-Oil (O/W/O) Double Emulsion Formation in a Simple and Robust Co-Flowing Microfluidic Device
Next Article in Special Issue
Rethinking the Design of Low-Cost Point-of-Care Diagnostic Devices
Previous Article in Journal
Towards Multiplex Molecular Diagnosis—A Review of Microfluidic Genomics Technologies
Open AccessFeature PaperArticle

A Single-Use, Self-Powered, Paper-Based Sensor Patch for Detection of Exercise-Induced Hypoglycemia

Bioelectronics & Microsystems Laboratory, Department of Electrical & Computer Engineering, State University of New York-Binghamton, Binghamton, NY 13902, USA
*
Author to whom correspondence should be addressed.
Micromachines 2017, 8(9), 265; https://doi.org/10.3390/mi8090265
Received: 27 July 2017 / Revised: 23 August 2017 / Accepted: 27 August 2017 / Published: 31 August 2017
(This article belongs to the Special Issue Paper-Based Transducers and Electronics)
We report a paper-based self-powered sensor patch for prevention and management of exercise-induced hypoglycemia. The article describes the fabrication, in vitro, and in vivo characterization of the sensor for glucose monitoring in human sweat. This wearable, non-invasive, single-use biosensor integrates a vertically stacked, paper-based glucose/oxygen enzymatic fuel cell into a standard Band-Aid adhesive patch. The paper-based device attaches directly to skin, wicks sweat by using capillary forces to a reservoir where chemical energy is converted to electrical energy, and monitors glucose without external power and sophisticated readout instruments. The device utilizes (1) a 3-D paper-based fuel cell configuration, (2) an electrically conducting microfluidic reservoir for a high anode surface area and efficient mass transfer, and (3) a direct electron transfer between glucose oxidase and anodes for enhanced electron discharge properties. The developed sensor shows a high linearity of current at 0.02–1.0 mg/mL glucose centration (R2 = 0.989) with a high sensitivity of 1.35 µA/mM. View Full-Text
Keywords: sweat sensor patch; self-powered glucose sensor; enzymatic fuel cell; paper-based device; exercise-induced hypoglycemia sweat sensor patch; self-powered glucose sensor; enzymatic fuel cell; paper-based device; exercise-induced hypoglycemia
Show Figures

Graphical abstract

MDPI and ACS Style

Cho, E.; Mohammadifar, M.; Choi, S. A Single-Use, Self-Powered, Paper-Based Sensor Patch for Detection of Exercise-Induced Hypoglycemia. Micromachines 2017, 8, 265.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop