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259 Results Found

  • Article
  • Open Access
8 Citations
4,196 Views
14 Pages

Applicability of the Cox–Merz Relationship for Mayonnaise Enriched with Natural Extracts

  • Somaris E. Quintana,
  • Maria Zuñiga-Navarro,
  • David Ramirez-Brewer and
  • Luis A. García-Zapateiro

27 October 2023

The Cox and Merz rules are empirical correlations between the apparent viscosity of polymers with the effect of shear rate and the complex dynamic viscosity with the effect of frequency. In this study, the rheological properties of mayonnaise-type em...

  • Article
  • Open Access
18 Citations
5,243 Views
13 Pages

Applicability of the Cox-Merz Rule to High-Density Polyethylene Materials with Various Molecular Masses

  • Raffael Rathner,
  • Wolfgang Roland,
  • Hanny Albrecht,
  • Franz Ruemer and
  • Jürgen Miethlinger

9 April 2021

The Cox-Merz rule is an empirical relationship that is commonly used in science and industry to determine shear viscosity on the basis of an oscillatory rheometry test. However, it does not apply to all polymer melts. Rheological data are of major im...

(This article belongs to the Special Issue Rheology and Processing of Polymers)
  • Article
  • Open Access
4,250 Views
15 Pages

2 January 2025

This article examines nomadism through the conceptual framework of philosopher Rosi Braidotti, analyzing its implications for contemporary artistic practices. By focusing on case studies, including Italian artist Mario Merz’s igloos and Peruvia...

(This article belongs to the Section Visual Arts)
  • Article
  • Open Access
6 Citations
3,867 Views
23 Pages

14 November 2023

The high-pressure capillary rheometer (HPCR) represents a state-of-the-art instrument for the determination of rheological properties for plastics and rubber compounds. Rubber compounds have an increased tendency to exhibit flow anomalies depending o...

(This article belongs to the Special Issue Rheological Properties of Polymers and Polymer Composites)
  • Article
  • Open Access
3 Citations
4,701 Views
29 Pages

One-Year Change Methodologies for Fixed-Sum Insurance Contracts

  • Michel Dacorogna,
  • Alessandro Ferriero and
  • David Krief

30 July 2018

We study the dynamics of the one-year change in P&C insurance reserves estimation by analyzing the process that leads to the ultimate risk in the case of “fixed-sum” insurance contracts. The random variable ultimately is supposed to f...

  • Article
  • Open Access
24 Citations
4,210 Views
17 Pages

1 October 2020

Low-concentrated colloidal chitosan systems undergoing a thermally induced sol–gel phase transition are willingly studied due to their potential use as minimally invasive injectable scaffolds. Nevertheless, instrumental injectability tests to d...

(This article belongs to the Section Polymer Analysis and Characterization)
  • Article
  • Open Access
7 Citations
4,549 Views
21 Pages

Pooled Safety Analysis of IncobotulinumtoxinA in the Treatment of Neurological Disorders in Adults

  • Wolfgang H. Jost,
  • Petr Kaňovský,
  • Michael A. Hast,
  • Angelika Hanschmann and ,
  • Michael Althaus and
  • Atul T. Patel
  • + 1 author+ 0 author

23 May 2023

The pooled incidences of treatment-emergent adverse events (TEAEs) were examined by indication using the integrated clinical database of Merz-sponsored, placebo-controlled, or repeat-dose studies of incobotulinumtoxinA in adults with cervical dystoni...

  • Article
  • Open Access
8 Citations
2,728 Views
25 Pages

1 August 2023

Plastic pollution has become a global concern, demanding urgent attention and concerted efforts to mitigate its environmental impacts. Biodegradable plastics have emerged as a potential solution, offering the prospect of reduced harm through degradat...

(This article belongs to the Special Issue 3D Printing of Polymer Composites)
  • Article
  • Open Access
2 Citations
1,362 Views
18 Pages

Rescaling Flow Curves of Protein-Stabilized Emulsions

  • Santiago F. Velandia,
  • Philippe Marchal,
  • Véronique Sadtler,
  • Cécile Lemaitre and ,
  • Daniel Bonn and
  • Thibault Roques-Carmes
  • + 1 author+ 0 author

25 April 2025

In this study, we investigate the flow behavior of oil-in-water Pickering emulsions stabilized with bovine serum albumin (BSA). Through the use of a phase transition analogy and scaling parameters previously applied to surfactant-stabilized emulsions...

(This article belongs to the Section Synthesis, Interfaces and Nanostructures)
  • Article
  • Open Access
107 Views
30 Pages

Oscillatory Stiffness Versus Creep–Recovery Response of Recycled High-Density Polyethylene/Waste Engine Oil Modified Bitumen

  • Hassan Shuaibu Abdulrahman,
  • Michael Chiahemba Iorpenda,
  • Muhammed Fatih Yentimur,
  • Ali Almusawi and
  • Mustafa Albdairi

7 November 2026

Recycled high-density polyethylene (HDPE) and waste engine oil (WEO) can be combined to modify bitumen, but the high-temperature performance of such binders is often judged from oscillatory measurements alone. This study compares the oscillatory and...

(This article belongs to the Special Issue Polymer-Enabled Materials for Circular and Sustainable Pavements)
  • Article
  • Open Access
3,214 Views
7 Pages

Which Histometric Analysis Approach Is More Reliable for Assessing Histological Bone Tissue Samples?

  • Rodrigo dos Santos Pereira,
  • Carlos Fernando Mourão,
  • Adriano Piattelli,
  • Georgios E. Romanos and ,
  • Bruno Coelho Mendes,
  • Flavio Giubilato,
  • Pietro Montemezzi,
  • Jadson Júnior Conforte,
  • Geraldo Luiz Griza and
  • Eduardo Hochuli-Vieira
  • + 6 authors+ 1 author

28 September 2022

This study aims to evaluate the grid of Merz and ImageJ methods for histometric quantification, verifying which is more reliable and defining which is most suitable based on the time required to perform. Thirty histological samples of maxillary sinus...

(This article belongs to the Special Issue Advances in Oral Surgery and Implant Dentistry)
  • Article
  • Open Access
22 Citations
8,302 Views
17 Pages

28 April 2017

In the wake of the postsecular turn, we propose to reappraise both the religious as studied in anthropology and how anthropologists who have religious or spiritual interests can contribute to an emerging postsecular anthropology. Such an anthropology...

  • Article
  • Open Access
3 Citations
3,393 Views
13 Pages

Viscoelasticity and Solution Stability of Cyanoethylcellulose with Different Molecular Weights in Aqueous Solution

  • Qian Li,
  • Yuehu Li,
  • Zehua Jin,
  • Yujie Li and ,
  • Yifan Chen and
  • Jinping Zhou
  • + 1 author+ 0 author

Water-soluble cellulose ethers are widely used as stabilizers, thickeners, and viscosity modifiers in many industries. Understanding rheological behavior of the polymers is of great significance to the effective control of their applications. In this...

(This article belongs to the Special Issue Functional Biomass Derived Materials)
  • Article
  • Open Access
5 Citations
2,652 Views
23 Pages

Climate Risk and Conservation Challenges at Palermo’s Specola Museum

  • Maria Rosalia Carotenuto,
  • Ileana Chinnici,
  • Dario Camuffo,
  • Antonio della Valle and ,
  • Fernanda Prestileo,
  • Bartolomeo Megna,
  • Giuseppe Cavallaro and
  • Giuseppe Lazzara
  • + 3 authors+ 0 author

14 December 2024

The Specola Museum is housed on the premises of the old Palermo Observatory, founded in 1790, and preserves most of the observatory’s cultural heritage. Environmental monitoring following the activation of air conditioning systems in 2018 revea...

(This article belongs to the Special Issue Challenges to Heritage Conservation under Climate Change)
  • Article
  • Open Access
11 Citations
3,760 Views
12 Pages

Multicenter Retrospective Analysis of Second-Line Therapy after Gemcitabine Plus Nab-Paclitaxel in Advanced Pancreatic Cancer Patients

  • Valeria Merz,
  • Alessandro Cavaliere,
  • Carlo Messina,
  • Massimiliano Salati and ,
  • Camilla Zecchetto,
  • Simona Casalino,
  • Michele Milella,
  • Orazio Caffo and
  • Davide Melisi
  • + 4 authors+ 0 author

30 April 2020

Pancreatic cancer is one of the most lethal solid tumors. In many European countries gemcitabine plus nab-paclitaxel is the preferred first-line treatment. An increasing number of patients are eligible for second-line therapy, but the best regimen is...

  • Article
  • Open Access
17 Citations
4,421 Views
18 Pages

The Glasgow Prognostic Score at Diagnosis Is a Predictor of Clinical Outcome in Patients with Multiple Myeloma Undergoing Autologous Haematopoietic Stem Cell Transplantation

  • Hanno M. Witte,
  • Bastian Bonorden,
  • Armin Riecke,
  • Harald Biersack and ,
  • Konrad Steinestel,
  • Hartmut Merz,
  • Alfred C. Feller,
  • Veronica Bernard,
  • Sebastian Fetscher and
  • Niklas Gebauer
  • + 6 authors+ 1 author

9 April 2020

Background: Immunity and inflammatory response affect the tumour microenvironment and the progression of malignancies. Metabolic and inflammatory parameters and ratios of the peripheral blood correlate with outcome in cancer patients. There exist sev...

  • Article
  • Open Access
12 Citations
3,905 Views
25 Pages

Metastasis of Uveal Melanoma with Monosomy-3 Is Associated with a Less Glycogenetic Gene Expression Profile and the Dysregulation of Glycogen Storage

  • Siranush Vardanyan,
  • Anton Brosig,
  • Hartmut Merz,
  • Mahdy Ranjbar and ,
  • Vinodh Kakkassery,
  • Salvatore Grisanti and
  • Aysegül Tura
  • + 2 authors+ 0 author

29 July 2020

The prolonged storage of glucose as glycogen can promote the quiescence of tumor cells, whereas the accumulation of an aberrant form of glycogen without the primer protein glycogenin can induce the metabolic switch towards a glycolytic phenotype. Her...

  • Review
  • Open Access
42 Citations
10,052 Views
21 Pages

The COVID-19 Pandemic: Does Our Early Life Environment, Life Trajectory and Socioeconomic Status Determine Disease Susceptibility and Severity?

  • Cyrielle Holuka,
  • Myriam P. Merz,
  • Sara B. Fernandes,
  • Eleftheria G. Charalambous and ,
  • Snehaa V. Seal,
  • Nathalie Grova and
  • Jonathan D. Turner
  • + 2 authors+ 0 author

A poor socioeconomic environment and social adversity are fundamental determinants of human life span, well-being and health. Previous influenza pandemics showed that socioeconomic factors may determine both disease detection rates and overall outcom...

(This article belongs to the Special Issue Epigenetic and Molecular Consequences of Early-Life Trauma)
  • Perspective
  • Open Access
11 Citations
5,544 Views
14 Pages

The Interaction of the Endogenous Hydrogen Sulfide and Oxytocin Systems in Fluid Regulation and the Cardiovascular System

  • Nicole Denoix,
  • Oscar McCook,
  • Sarah Ecker,
  • Rui Wang and ,
  • Christiane Waller,
  • Peter Radermacher and
  • Tamara Merz
  • + 2 authors+ 0 author

14 August 2020

The purpose of this review is to explore the parallel roles and interaction of hydrogen sulfide (H2S) and oxytocin (OT) in cardiovascular regulation and fluid homeostasis. Their interaction has been recently reported to be relevant during physical an...

(This article belongs to the Special Issue Hydrogen Sulfide in Biology)
  • Article
  • Open Access
14 Citations
3,787 Views
12 Pages

Spatial Distribution of Focal Lesions in Whole-Body MRI and Influence of MRI Protocol on Staging in Patients with Smoldering Multiple Myeloma According to the New SLiM-CRAB-Criteria

  • Markus Wennmann,
  • Thomas Hielscher,
  • Laurent Kintzelé,
  • Bjoern H. Menze and ,
  • Georg Langs,
  • Maximilian Merz,
  • Sandra Sauer,
  • Hans-Ulrich Kauczor,
  • Heinz-Peter Schlemmer and
  • Marc-André Weber
  • + 9 authors+ 4 authors

7 September 2020

The purpose of this study was to assess how different MRI protocols (spinal vs. spinal plus pelvic vs. whole-body (wb)-MRI) affect staging in patients with smoldering multiple myeloma (SMM), according to the SLiM-CRAB-criterion ‘>1 focal les...

(This article belongs to the Section Cancer Causes, Screening and Diagnosis)
  • Article
  • Open Access
14 Citations
4,231 Views
15 Pages

In Vivo Confocal Microscopy of the Corneal-Conjunctival Transition in the Evaluation of Epithelial Renewal after SLET

  • Emilio Pedrotti,
  • Chiara Chierego,
  • Tiziano Cozzini,
  • Tommaso Merz and ,
  • Neil Lagali,
  • Alessandra De Gregorio,
  • Adriano Fasolo,
  • Erika Bonacci,
  • Jacopo Bonetto and
  • Giorgio Marchini
  • + 5 authors+ 0 author

6 November 2020

Examination of the corneal surface by in vivo confocal microscopy (IVCM) allows for objective identification of corneal and conjunctival cell phenotypes to evaluate different epithelialization patterns. Detection of a corneal-conjunctival epithelial...

(This article belongs to the Special Issue Updates in Ocular Surgery)
  • Article
  • Open Access
7 Citations
3,686 Views
19 Pages

Systemic Inflammation and Tumour-Infiltrating T-Cell Receptor Repertoire Diversity Are Predictive of Clinical Outcome in High-Grade B-Cell Lymphoma with MYC and BCL2 and/or BCL6 Rearrangements

  • Vito Olschewski,
  • Hanno M. Witte,
  • Veronica Bernard,
  • Konrad Steinestel and ,
  • Wolfgang Peter,
  • Hartmut Merz,
  • Johannes Rieken,
  • Harald Biersack,
  • Nikolas von Bubnoff and
  • Niklas Gebauer
  • + 6 authors+ 1 author

20 February 2021

High-grade B-cell lymphoma, with MYC and BCL2 and/or BCL6 rearrangements (double/triple-hit high grade B-cell lymphoma, HGBL-DH/TH) constitutes a provisional entity among B-cell malignancies with an aggressive behavior and dire prognosis. While evide...

(This article belongs to the Section Tumor Microenvironment)
  • Article
  • Open Access
12 Citations
3,583 Views
15 Pages

Analyzing Longitudinal wb-MRI Data and Clinical Course in a Cohort of Former Smoldering Multiple Myeloma Patients: Connections between MRI Findings and Clinical Progression Patterns

  • Markus Wennmann,
  • Thomas Hielscher,
  • Laurent Kintzelé,
  • Bjoern H. Menze and ,
  • Georg Langs,
  • Maximilian Merz,
  • Sandra Sauer,
  • Hans-Ulrich Kauczor,
  • Heinz-Peter Schlemmer and
  • Marc-André Weber
  • + 9 authors+ 4 authors

25 February 2021

The purpose of this study was to analyze size and growth dynamics of focal lesions (FL) as well as to quantify diffuse infiltration (DI) in untreated smoldering multiple myeloma (SMM) patients and correlate those MRI features with timepoint and cause...

(This article belongs to the Special Issue Gammopathies of Certain Significance: Managing MGUS and Smoldering Myeloma)
  • Article
  • Open Access
7 Citations
3,289 Views
13 Pages

ΔMST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage

  • Britta Trautwein,
  • Tamara Merz,
  • Nicole Denoix,
  • Csaba Szabo and ,
  • Enrico Calzia,
  • Peter Radermacher and
  • Oscar McCook
  • + 2 authors+ 0 author

3 February 2021

Genetic deletion of 3-mercaptopyruvate sulfurtransferase (MST) is known to result in hypertension and cardiac hypertrophy in older mice, and is associated with increased anxiety-like behaviors. Endogenous hydrogen sulfide (H2S) produced by MST in the...

(This article belongs to the Special Issue Hydrogen Sulfide in Biology)
  • Review
  • Open Access
325 Citations
65,550 Views
47 Pages

Service Robots in the Healthcare Sector

  • Jane Holland,
  • Liz Kingston,
  • Conor McCarthy,
  • Eddie Armstrong and ,
  • Peter O’Dwyer,
  • Fionn Merz and
  • Mark McConnell
  • + 2 authors+ 0 author

11 March 2021

Traditionally, advances in robotic technology have been in the manufacturing industry due to the need for collaborative robots. However, this is not the case in the service sectors, especially in the healthcare sector. The lack of emphasis put on the...

(This article belongs to the Section Medical Robotics and Service Robotics)
  • Article
  • Open Access
16 Citations
4,997 Views
17 Pages

Commissioning Results and Electron Beam Characterization with the S-Band Photoinjector at SINBAD-ARES

  • Eva Panofski,
  • Ralph Assmann,
  • Florian Burkart,
  • Ulrich Dorda and ,
  • Luca Genovese,
  • Farzad Jafarinia,
  • Sonja Jaster-Merz,
  • Max Kellermeier,
  • Willi Kuropka and
  • Sumera Yamin
  • + 10 authors+ 5 authors

Over the years, the generation and acceleration of ultra-short, high quality electron beams has attracted more and more interest in accelerator science. Electron bunches with these properties are necessary to operate and test novel diagnostics and ad...

  • Perspective
  • Open Access
6 Citations
6,672 Views
25 Pages

Biological Connection of Psychological Stress and Polytrauma under Intensive Care: The Role of Oxytocin and Hydrogen Sulfide

  • Tamara Merz,
  • Oscar McCook,
  • Nicole Denoix,
  • Peter Radermacher and ,
  • Christiane Waller and
  • Thomas Kapapa
  • + 1 author+ 0 author

25 August 2021

This paper explored the potential mediating role of hydrogen sulfide (H2S) and the oxytocin (OT) systems in hemorrhagic shock (HS) and/or traumatic brain injury (TBI). Morbidity and mortality after trauma mainly depend on the presence of HS and/or TB...

(This article belongs to the Special Issue Advances in Oxytocin)
  • Perspective
  • Open Access
15 Citations
5,442 Views
25 Pages

H2S and Oxytocin Systems in Early Life Stress and Cardiovascular Disease

  • Oscar McCook,
  • Nicole Denoix,
  • Peter Radermacher,
  • Christiane Waller and
  • Tamara Merz

6 August 2021

Today it is well established that early life stress leads to cardiovascular programming that manifests in cardiovascular disease, but the mechanisms by which this occurs, are not fully understood. This perspective review examines the relevant literat...

(This article belongs to the Special Issue Effects of Stress and Psychological Trauma on the Development and Progression of Cardiovascular Diseases)
  • Review
  • Open Access
24 Citations
10,062 Views
29 Pages

The Coronavirus Disease 2019 (COVID-19): Key Emphasis on Melatonin Safety and Therapeutic Efficacy

  • Eva Ramos,
  • Francisco López-Muñoz,
  • Emilio Gil-Martín,
  • Javier Egea and ,
  • Iris Álvarez-Merz,
  • Sakshi Painuli,
  • Prabhakar Semwal,
  • Natália Martins,
  • Jesús M. Hernández-Guijo and
  • Alejandro Romero
  • + 5 authors+ 0 author

Viral infections constitute a tectonic convulsion in the normophysiology of the hosts. The current coronavirus disease 2019 (COVID-19) pandemic is not an exception, and therefore the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infect...

(This article belongs to the Special Issue Melatonin and Related Compounds: Antioxidant and Anti-inflammatory Actions)
  • Article
  • Open Access
17 Citations
3,795 Views
13 Pages

Correlation of Pulse Wave Transit Time with Pulmonary Artery Pressure in a Porcine Model of Pulmonary Hypertension

  • Fabian Mueller-Graf,
  • Jonas Merz,
  • Tim Bandorf,
  • Chiara Felicitas Albus and ,
  • Maike Henkel,
  • Lisa Krukewitt,
  • Volker Kühn,
  • Susanne Reuter,
  • Brigitte Vollmar and
  • Amelie Zitzmann
  • + 8 authors+ 3 authors

13 September 2021

For the non-invasive assessment of pulmonary artery pressure (PAP), surrogates like pulse wave transit time (PWTT) have been proposed. The aim of this study was to invasively validate for which kind of PAP (systolic, mean, or diastolic) PWTT is the b...

(This article belongs to the Section Molecular and Translational Medicine)
  • Feature Paper
  • Article
  • Open Access
8 Citations
5,015 Views
21 Pages

Anammox-Based Processes for Mature Leachate Treatment in SBR: A Modelling Study

  • Anna Lanzetta,
  • Davide Mattioli,
  • Francesco Di Capua,
  • Gianpaolo Sabia and ,
  • Luigi Petta,
  • Giovanni Esposito,
  • Gianni Andreottola,
  • Giovanni Gatti,
  • Willy Merz and
  • Michela Langone
  • + 5 authors+ 0 author

19 August 2021

Mature landfill leachates are characterized by high levels of ammoniacal nitrogen which must be reduced for discharge in the sewer system and further treatment in municipal wastewater treatment plants. The use of anammox-based processes can allow for...

(This article belongs to the Special Issue Anammox-Based Processes for Wastewater Treatment)
  • Article
  • Open Access
6 Citations
12,232 Views
14 Pages

Can 18F-NaF PET/CT before Autologous Stem Cell Transplantation Predict Survival in Multiple Myeloma?

  • Christos Sachpekidis,
  • Annette Kopp-Schneider,
  • Maximilian Merz,
  • Anna Jauch and ,
  • Marc-Steffen Raab,
  • Hartmut Goldschmidt and
  • Antonia Dimitrakopoulou-Strauss
  • + 2 authors+ 0 author

23 May 2020

There is an unmet need for positron emission tomography (PET) radiotracers that can image bone disease in multiple myeloma (MM) in a more sensitive and specific way than the widely used 18F-fluorodeoxyglucose (18F-FDG). Sodium fluoride (18F-NaF) is a...

(This article belongs to the Special Issue PET/CT in Multiple Myeloma Patients)
  • Article
  • Open Access
18 Citations
6,744 Views
18 Pages

Fabrication and Characterization of Single-Crystal Diamond Membranes for Quantum Photonics with Tunable Microcavities

  • Julia Heupel,
  • Maximilian Pallmann,
  • Jonathan Körber,
  • Rolf Merz and ,
  • Michael Kopnarski,
  • Rainer Stöhr,
  • Johann Peter Reithmaier,
  • David Hunger and
  • Cyril Popov
  • + 4 authors+ 0 author

4 December 2020

The development of quantum technologies is one of the big challenges in modern research. A crucial component for many applications is an efficient, coherent spin–photon interface, and coupling single-color centers in thin diamond membranes to a...

(This article belongs to the Section D: Materials and Processing)
  • Article
  • Open Access
13 Citations
4,012 Views
19 Pages

Monosomy-3 Alters the Expression Profile of the Glucose Transporters GLUT1-3 in Uveal Melanoma

  • Tjorge Maaßen,
  • Siranush Vardanyan,
  • Anton Brosig,
  • Hartmut Merz and ,
  • Mahdy Ranjbar,
  • Vinodh Kakkassery,
  • Salvatore Grisanti and
  • Aysegül Tura
  • + 3 authors+ 0 author

8 December 2020

Monosomy-3 in uveal melanoma (UM) cells increases the risk of fatal metastases. The gene encoding the low-affinity glucose transporter GLUT2 resides on chromosome 3q26.2. Here, we analyzed the expression of the glucose transporters GLUT1, GLUT2, and...

(This article belongs to the Special Issue Genetic Basis and Molecular Mechanisms of Uveal Melanomas)
  • Article
  • Open Access
57 Citations
6,660 Views
26 Pages

Inter-Comparison of Gauge-Based Gridded Data, Reanalysis and Satellite Precipitation Product with an Emphasis on Hydrological Modeling

  • Sridhara Setti,
  • Rathinasamy Maheswaran,
  • Venkataramana Sridhar,
  • Kamal Kumar Barik and ,
  • Bruno Merz and
  • Ankit Agarwal
  • + 1 author+ 0 author

20 November 2020

Precipitation is essential for modeling the hydrologic behavior of watersheds. There exist multiple precipitation products of different sources and precision. We evaluate the influence of different precipitation product on model parameters and stream...

(This article belongs to the Special Issue Emerging Hydro-Climatic Patterns, Teleconnections and Extreme Events in Changing World at Different Timescales)
  • Article
  • Open Access
29 Citations
14,720 Views
30 Pages

Engineering Human–Machine Teams for Trusted Collaboration

  • Basel Alhaji,
  • Janine Beecken,
  • Rüdiger Ehlers,
  • Jan Gertheiss and ,
  • Felix Merz,
  • Jörg P. Müller,
  • Michael Prilla,
  • Andreas Rausch,
  • Andreas Reinhardt and
  • Jürgen Zimmermann
  • + 10 authors+ 5 authors

The way humans and artificially intelligent machines interact is undergoing a dramatic change. This change becomes particularly apparent in domains where humans and machines collaboratively work on joint tasks or objects in teams, such as in industri...

  • Article
  • Open Access
10 Citations
4,124 Views
8 Pages

Genome-Wide Survey for Microdeletions or -Duplications in 155 Patients with Lower Urinary Tract Obstructions (LUTO)

  • Luca M. Schierbaum,
  • Sophia Schneider,
  • Stefan Herms,
  • Sugirthan Sivalingam and ,
  • Julia Fabian,
  • Heiko Reutter,
  • Stefanie Weber,
  • Waltraut M. Merz,
  • Marcin Tkaczyk and
  • Alina C. Hilger
  • + 15 authors+ 10 authors

20 September 2021

Lower urinary tract obstruction (LUTO) is, in most cases, caused by anatomical blockage of the bladder outlet. The most common form are posterior urethral valves (PUVs), a male-limited phenotype. Here, we surveyed the genome of 155 LUTO patients to i...

(This article belongs to the Special Issue De novo Mutations and the Lack of Heritability in Birth Defects)
  • Article
  • Open Access
2 Citations
4,452 Views
10 Pages

23 September 2021

Within the neuropsychological assessment, clinicians are responsible for ensuring the validity of obtained cognitive data. As such, increased attention is being paid to performance validity in patients with multiple sclerosis (pwMS). Experts have pro...

(This article belongs to the Special Issue Advances in Multiple Sclerosis)
  • Feature Paper
  • Article
  • Open Access
14 Citations
5,649 Views
15 Pages

Biosynthesis of Furfurylamines in Batch and Continuous Flow by Immobilized Amine Transaminases

  • Tobias Heinks,
  • Luisa M. Merz,
  • Jan Liedtke,
  • Matthias Höhne and ,
  • Luuk M. van Langen,
  • Uwe T. Bornscheuer,
  • Gabriele Fischer von Mollard and
  • Per Berglund
  • + 3 authors+ 0 author

11 May 2023

Building blocks with amine functionality are crucial in the chemical industry. Biocatalytic syntheses and chemicals derived from renewable resources are increasingly desired to achieve sustainable production of these amines. As a result, renewable ma...

(This article belongs to the Special Issue Supported Biocatalysts for Sustainable Chemistry)
  • Article
  • Open Access
9 Citations
13,807 Views
16 Pages

21 March 2023

Gratitude interventions can provide cost-effective support for mental health to under-resourced schools. This study aims to better understand the effects of a promising intervention Bono et al. evaluated in 2020. Using a quasi-experimental design (wh...

(This article belongs to the Special Issue Social and Emotional Education in Schools)
  • Brief Report
  • Open Access
1 Citations
2,168 Views
6 Pages

Maternal and Perinatal Outcome in a Contemporary Cohort of Patients with Portal Hypertension: A Single-Center Experience

  • Philipp Kosian,
  • Christian Jansen,
  • Johannes Chang,
  • Michael Praktiknjo and ,
  • Tiyasha Hosne Ayub,
  • Ulrich Gembruch and
  • Waltraut M. Merz
  • + 2 authors+ 0 author

24 April 2023

Background: Portal hypertension in pregnancy is characterized by an increased perinatal and maternal complication rate. The purpose of this study was to evaluate the perinatal and maternal outcomes of these high-risk pregnancies at our tertiary cente...

(This article belongs to the Section Obstetrics & Gynecology)
  • Article
  • Open Access
4 Citations
2,627 Views
14 Pages

Effect of Lifestyle Interventions during Pregnancy on Maternal Leptin, Resistin and Offspring Weight at Birth and One Year of Life

  • Nina Ferrari,
  • Nikola Schmidt,
  • Lisa Schmidt,
  • Waltraut M. Merz and ,
  • Konrad Brockmeier,
  • Jörg Dötsch,
  • Inga Bae-Gartz,
  • Esther Mahabir and
  • Christine Joisten
  • + 4 authors+ 0 author

Lifestyle during pregnancy impacts the health of the mother and child. However, the extent to which physical activity affects maternal biomarkers and factors that might influence birth weight remains unclear. We analysed data from two lifestyle inter...

(This article belongs to the Special Issue 10th Anniversary of Biomedicines—Recent Advances on Adipokines)
  • Systematic Review
  • Open Access
18 Citations
7,995 Views
23 Pages

Perioperative Drug Treatment in Pancreatic Surgery—A Systematic Review and Meta-Analysis

  • Ingmar F. Rompen,
  • Daniela C. Merz,
  • Karam T. Alhalabi,
  • Rosa Klotz and ,
  • Eva Kalkum,
  • Thomas M. Pausch,
  • Hendrik Strothmann and
  • Pascal Probst
  • + 3 authors+ 0 author

22 February 2023

Introduction: Pancreatic resections for malignant or benign diseases are associated with major morbidity and changes in physiology. To reduce perioperative complications and enhance recovery, many types of perioperative medical management have been i...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Protocol
  • Open Access
1 Citations
2,566 Views
11 Pages

Targeting FGFR Pathway Is Not an Effective Therapeutic Strategy in Patients with Unselected Metastatic Esophagogastric Cancer Resistant to Trastuzumab

  • Camilla Zecchetto,
  • Alberto Quinzii,
  • Simona Casalino,
  • Marina Gaule and ,
  • Camilla Pesoni,
  • Valeria Merz,
  • Silvia Pietrobono,
  • Domenico Mangiameli,
  • Martina Pasquato and
  • Davide Melisi
  • + 10 authors+ 5 authors

11 March 2023

Trastuzumab plus chemotherapy is the standard of care for the first-line treatment of patients with HER2+ advanced esophagogastric (EG) cancer. Nevertheless, patients frequently develop resistance. In preclinical models, we identified the overexpress...

(This article belongs to the Section Omics/Informatics)
  • Article
  • Open Access
13 Citations
6,982 Views
19 Pages

Vaccination of Zoo Birds against West Nile Virus—A Field Study

  • Felicitas Bergmann,
  • Dominik Fischer,
  • Luisa Fischer,
  • Heike Maisch and ,
  • Tina Risch,
  • Saskia Dreyer,
  • Balal Sadeghi,
  • Dietmar Geelhaar,
  • Lisa Grund and
  • Ute Ziegler
  • + 7 authors+ 2 authors

14 March 2023

West Nile virus (WNV) is known to cause disease and death in humans and various animals worldwide. WNV has circulated in Germany since 2018. In 2020, four birds tested positive for the WNV genome at Zoopark Erfurt (Thuringia). Moreover, virus neutral...

(This article belongs to the Special Issue New Approaches in Vaccine Development for the Control of Vectors and Vector-Borne Diseases)
  • Article
  • Open Access
6 Citations
4,265 Views
9 Pages

Achieving Ultra-Low Friction with Diamond/Metal Systems in Extreme Environments

  • Pantcho Stoyanov,
  • Rolf Merz,
  • Markus Stricker,
  • Michael Kopnarski and
  • Martin Dienwiebel

7 July 2021

In the search for achieving ultra-low friction for applications in extreme environments, we evaluate the interfacial processes of diamond/tungsten sliding contacts using an on-line macro-tribometer and a micro-tribometer in an ultra-high vacuum. The...

(This article belongs to the Special Issue Tribology and Surface Engineering 2021)
  • Article
  • Open Access
8 Citations
3,582 Views
12 Pages

Relationship between Physical Activity and the Metabolic, Inflammatory Axis in Pregnant Participants

  • Adeline Bockler,
  • Nina Ferrari,
  • Clara Deibert,
  • Anne Flöck and ,
  • Waltraut M. Merz,
  • Ulrich Gembruch,
  • Christina Ehrhardt,
  • Jörg Dötsch and
  • Christine Joisten
  • + 4 authors+ 0 author

Physical activity (PA) during pregnancy is beneficial for mother and child. Little is known regarding the effects of PA on specific adipokines/myokines and their impact during pregnancy. This study investigates the correlation between PA during late...

(This article belongs to the Special Issue Physical Activity and Public Health: Addressing Gaps in Research for Special Population Subgroups)
  • Article
  • Open Access
4 Citations
2,712 Views
8 Pages

Deleterious Association of Inhalant Use on Sleep Quality during the COVID-19 Pandemic

  • Deepti Gunge,
  • Jordan Marganski,
  • Ira Advani,
  • Shreyes Boddu and ,
  • Yi Jan Ella Chen,
  • Sagar Mehta,
  • William Merz,
  • Ana Lucia Fuentes,
  • Atul Malhotra and
  • Laura E. Crotty Alexander
  • + 6 authors+ 1 author

The COVID-19 pandemic generated large amounts of stress across the globe. While acute stress negatively impacts health, defining exact consequences and behavioral interventions can be difficult. We hypothesized that a generalized increase in stress a...

(This article belongs to the Section Health Behavior, Chronic Disease and Health Promotion)
  • Article
  • Open Access
19 Citations
3,858 Views
11 Pages

Intravitreal Application: Physicochemical Properties of Drugs Dissolved in Silicone Oils of Different Density in Comparison to the Porcine Vitreous Body

  • Maximilian Hammer,
  • Sonja K. Schickhardt,
  • Patrick R. Merz,
  • Ramin Khoramnia and ,
  • Alexander F. Scheuerle,
  • Walter Mier,
  • Philipp Uhl and
  • Gerd U. Auffarth
  • + 3 authors+ 0 author

Silicone oil endotamponades provide a reservoir for drugs in the eye. Following vitrectomy surgery to treat retinal detachments, extensive diabetic retinopathy or endophthalmitis, they can be used as long-term lipophilic depots. This study aimed to i...

(This article belongs to the Special Issue Recent Advances in Ocular Drug Delivery)
  • Article
  • Open Access
5 Citations
2,933 Views
11 Pages

Brain-Derived Neurotrophic Factor in Gestational Diabetes: Analysis of Maternal Serum and Cord Blood Pairs and Comparison of Dietary- and Insulin-Dependent GDM

  • Michael Robert Jaskolski,
  • Anna Katharina Diedrich,
  • Alexandru Odainic,
  • Susanne Viktoria Schmidt and ,
  • Marie-Therese Schmitz,
  • Brigitte Strizek,
  • Ulrich Gembruch,
  • Waltraut Maria Merz and
  • Anne Flöck
  • + 4 authors+ 0 author

The Objective of our study was to investigate the influence of dietary (dGDM) and insulin-dependent (iGDM) gestational diabetes (GDM) on BDNF blood levels of corresponding maternal-neonatal pairs and compare them to pregnancies unaffected by GDM. Blo...

(This article belongs to the Section Integrative Metabolomics)

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