Submit to Special Issue Submit Abstract to Special Issue Review for Medicina Propose a Special Issue

Journal Menu

Journal Browser

► Journal Browser

Special Issue "Advances in Oral Surgery and Implant Dentistry"

Print Special Issue Flyer
Special Issue Editors
Special Issue Information
Keywords
Published Papers

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Dentistry".

Deadline for manuscript submissions: 10 December 2023 | Viewed by 13245

Share This Special Issue

Special Issue Editor

Dr. Roberto Sacco

E-Mail Website
Guest Editor

Division of Dentistry, School of Medical Sciences, The University of Manchester, Manchester, UK
Interests: dental implants; bone healing histology and histomorphometry; autologous bone regeneration; homologue bone regeneration; clinical research; iatrogenic oral bone disease; evidence-based medicine
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Over the past few years, oral surgery (OS) and implant dentistry (ID) have experienced constant improvements in many aspects of patient care. We have witnessed a remarkable development of new surgical protocols and the implementation of new technologies into clinical practice. Although the OS and ID specialties originated in dentistry, the field has attracted collaboration and knowledge from numerous disciplines, such as medicine, radiology, as well as biomedical engineering. The specialties’ ultimate goal is to provide evidence-based practices by minimizing patient morbidity and maximizing treatment success rate outcomes.

The objective of this issue is to focus on updates in recent or emerging practices in OS and ID patients. The research topic may include but is not limited to innovative surgical techniques and or protocols, advanced imaging in planning and delivery od surgical treatments, OS surgical treatment disorders, and OS and ID clinical studies. Research may be prospective or retrospective, and review articles are encouraged.

Dr. Roberto Sacco
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

oral surgery
implant dentistry
bone reconstruction
bone regeneration
diagnostic imaging
bone disease

Published Papers (11 papers)

Download All Papers

Research

Jump to: Review, Other

Open AccessArticle

Interdental Bone Level around Immediately Placed Implants at Maxillary and Mandibular Molar Sites: A Retrospective Radiographic Analysis

Mohammed Alasqah

Khalid S. Alzahrani

and

Khalid Gufran

Medicina 2023, 59(10), 1701; https://doi.org/10.3390/medicina59101701 - 23 Sep 2023

Viewed by 191

Abstract

Background and Objectives: The current study aimed to compare the amount of interdental bone loss between early and immediate implant placements. Materials and Methods: A total of 16 immediate implants and 16 early implants radiographs were included in the current research. The bone level was assessed at two different stages: at the extraction appointment (T1) and after three to six months of implant placement (T2). A line was drawn from the cemento-enamel junction connecting adjacent teeth to the interdental line connecting the interdental alveolar crest at both stages. The difference between measurements in the T1 and T2 stages is the bone loss measurement for the early implant group. For the immediate implant placement sites, the measurements were taken from the interdental bone crest to the implant platform level. Results: A Mann–Whitney U test was performed to evaluate the differences between both groups. The descriptive statistics of the T1 and T2 stages for both groups suggest that the bone loss in the T2 stage was generally higher than T1 stage. The immediate implant group showed higher bone loss compared to the early implant group. Moreover, there was significantly higher bone loss (p = 0.039) in the immediate implant group compared to the early implant group. Conclusions: The results of this study indicate that immediate implant might have disadvantages over early implant in terms of bone loss after the extraction of maxillary and mandibular molar teeth. Full article

(This article belongs to the Special Issue Advances in Oral Surgery and Implant Dentistry)

► Show Figures

Figure 1

Open AccessArticle

The Interplay of Raloxifene and Sonochemical Bio-Oss in Early Maxillary Sinus Bone Regeneration: A Histological and Immunohistochemical Analysis in Rabbits

Anderson Maikon de Souza Santos

Rodrigo dos Santos Pereira

Pietro Montemezzi

Rafael Coutinho Mello-Machado

Roberta Okamoto

Roberto Sacco

Paulo Noronha Lisboa-Filho

Michel Reis Messora

Carlos Fernando Mourão

and

Eduardo Hochuli-Vieira

Medicina 2023, 59(9), 1521; https://doi.org/10.3390/medicina59091521 - 23 Aug 2023

Viewed by 541

Abstract

The study aimed to assess the efficacy of using Raloxifene with ultrasonic processing to enhance Bio-Oss^®, a bone graft substitute, for maxillary sinus bone height reconstruction. A total of 24 rabbit maxillary sinuses were distributed into three groups, each receiving different treatments: Bio-Oss^® only, sonicated Bio-Oss, and sonicated Bio-Oss^® with Raloxifene. Surgical procedures and subsequent histomorphometric and immunohistochemistry analyses were conducted to evaluate the bone formation, connective tissue, and remaining biomaterial, as well as the osteoblastic differentiation and maturation of collagen fibers. Results indicated that the sonicated Bio-Oss^® and Bio-Oss^® groups showed similar histological behavior and bone formation, but the Raloxifene group displayed inflammatory infiltrate, low bone formation, and disorganized connective tissue. The statistical analysis confirmed significant differences between the groups in terms of bone formation, connective tissue, and remaining biomaterial. In conclusion, the study found that while sonicated Bio-Oss^® performed comparably to Bio-Oss^® alone, the addition of Raloxifene led to an unexpected delay in bone repair. The findings stress the importance of histological evaluation for accurate bone repair assessment and the necessity for further investigation into the local application of Raloxifene. Future research may focus on optimizing bone substitutes with growth factors to improve bone repair. Full article

(This article belongs to the Special Issue Advances in Oral Surgery and Implant Dentistry)

► Show Figures

Figure 1

Open AccessArticle

Mini-Implants Retaining Removable Partial Dentures in Subjects without Posterior Teeth: A 5-Year Prospective Study Comparing the Maxilla and the Mandible

and

Medicina 2023, 59(2), 237; https://doi.org/10.3390/medicina59020237 - 27 Jan 2023

Viewed by 1710

Abstract

Background and objectives: Long-term studies of clinical outcomes of mini-implants (MDIs) in the first premolar/canine sites retaining a bilateral free-ending removable partial dentures (RPD) in Kennedy class I subjects have not been well documented. The aim was to assess clinical outcomes in a prospective 5-year cohort study comparing the mandible and maxilla. Material and Methods: Participants (n = 92) who received two MDIs each and a new RPD were reviewed after one, three and five years. A total of 71 participants (82 mini-implants in the mandible; 58 in the maxilla) completed the study. Marginal bone level change, success, survival rates, Modified Plaque (MPI) and Bleeding Indices (MBI) were assessed. Results: The five-year success rate was 93.3% and 93.4% (p > 0.05), in the mandible and the maxilla, respectively. Mean peri-implant bone loss (MBL) increased significantly over five years (p < 0.01) to 0.50 mm in the mandible and 0.52 mm in the maxilla. Age had a significant effect on the MBL (higher rates in younger participants), while jaw of insertion, gender, and antagonistic jaw status did not. MPI and MBI were not significantly correlated with MBL. Conclusions: The insertion of two MDIs in previous first premolar/canine sites for retention of a free-end saddle RPD can be a successful treatment modality in subjects with narrow alveolar ridges. Full article

(This article belongs to the Special Issue Advances in Oral Surgery and Implant Dentistry)

► Show Figures

Figure 1

Open AccessArticle

Comparison of Digital Planimetry and Ruler Methods for the Measurement of Extraction Socket Wounds

Weal I. Ibraheem

Ashok Kumar Bhati

Nazeeha Ahmed Hakami

Abdulsalam Dhafer Alshehri

Mohammed Hassan M. Wadani

and

Fai Mohammed Essa Ageeli

Medicina 2023, 59(1), 135; https://doi.org/10.3390/medicina59010135 - 10 Jan 2023

Viewed by 868

Abstract

Background and objectives: The purpose of the study was to evaluate and compare ruler and digital planimetry methods to measure extraction socket wounds. Materials and Methods: In total, 41 extraction socket wounds were selected for assessment of wound area by ruler and digital planimetry methods. In the simple ruler method, the periodontal probe was utilized to measure the length and breadth of the extraction wound, whereas in the digital planimetry technique, Pictzar software was used. Data were analyzed using R software version 4.1.1 and Excel. For intergroup comparisons of wound surface area, Welch t-tests were used, and paired t-tests were used for intragroup comparisons. Intra-class correlation coefficients (ICC) and 95% confidence intervals (CIs) were used to evaluate the inter-method reliabilities of surface area. Results: Both ruler and digital planimetry techniques showed post-operative reductions in surface area. A significant difference was reported between the two techniques; however, the ruler method measurements were overestimated compared to those obtained with digital planimetry. Conclusions: This study concludes that digital planimetry techniques provide more accurate results when compared with the simple ruler method. Full article

(This article belongs to the Special Issue Advances in Oral Surgery and Implant Dentistry)

► Show Figures

Figure 1

Open AccessArticle

Does Melatonin Associated with Nanostructured Calcium Phosphate Improve Alveolar Bone Repair?

Camila Diuana de Almeida

Suelen Cristina Sartoretto

Adriana Terezinha Neves Novellino Alves

Rodrigo Figueiredo de Brito Resende

Jose de Albuquerque Calasans-Maia

and

Mônica Diuana Calasans-Maia

Medicina 2022, 58(12), 1720; https://doi.org/10.3390/medicina58121720 - 24 Nov 2022

Cited by 1 | Viewed by 995

Abstract

Background and objectives: Calcium phosphates have been widely used as bone substitutes, but their properties are limited to osteoconduction. The association of calcium phosphates with osteoinductive bioactive molecules has been used as a strategy in regenerative medicine. Melatonin has been studied due to its cell protection and antioxidant functions, reducing osteoclastic activity and stimulating newly formed bone. This study aimed to evaluate the effect of topical application of melatonin associated with nanostructured carbonated hydroxyapatite microspheres in the alveolar bone repair of Wistar rats through histological and histomorphometric analysis. Materials and Methods: Thirty female Wistar rats (300 g) were used, divided randomly into three experimental groups (n = 10), G1: nanostructured carbonated hydroxyapatite microspheres associated with melatonin gel (CHA-M); G2: nanostructured carbonated hydroxyapatite (CHA); G3: blood clot (without alveolar filling). The animals were euthanized after 7 and 42 days of the postoperative period and processed for histological and histomorphometric evaluation. Kruskal–Wallis and Dunn’s post-test were applied to investigate statistical differences between the groups at the same time point for new bone and connective tissue variables. Mann–Whitney was used to assess statistical differences between different time points and in the biomaterial variable. Results: Results showed a greater volume of residual biomaterial in the CHA-M than the CHA group (p = 0.007), and there were no significant differences in terms of newly formed bone and connective tissue between CHA and CHA-M after 42 days. Conclusions: This study concluded that both biomaterials improved alveolar bone repair from 7 to 42 days after surgery, and the association of CHA with melatonin gel reduced the biomaterial’s biodegradation at the implanted site but did not improve the alveolar bone repair. Full article

(This article belongs to the Special Issue Advances in Oral Surgery and Implant Dentistry)

► Show Figures

Figure 1

Open AccessArticle

Clinical Validation of Dental Implant Stability by Newly Designed Damping Capacity Assessment Device during the Healing Period

and

Medicina 2022, 58(11), 1570; https://doi.org/10.3390/medicina58111570 - 31 Oct 2022

Cited by 1 | Viewed by 1165

Abstract

Background and Objectives: To evaluate the stability of a dental implant and the effectiveness of a newly designed damping capacity assessment device by improving the number of blows and strength evaluated by a prospective clinical study. Materials and Method: The stability of dental implants was measured in 50 implants in a total of 38 patients. Measurements were performed using Anycheck and Periotest M devices, twice in total, divided into buccal and lingual directions. In addition, measurements were performed on the day of surgery, two weeks, one month, two months, and three months after surgery for a total of five times. After the standardization of the measured values, the differences and changes over time for each device were observed. Result: No difference in standardized values between the two devices was observed at any time point. In both devices, stability decreased at two weeks postoperatively but gradually increased thereafter. No differences were observed in the values according to the measurement direction. Conclusions: The damping capacity of Anycheck was similar to that of Periotest M. After a slight decrease in stability two weeks after implant placement, implant stability increased over time. Full article

(This article belongs to the Special Issue Advances in Oral Surgery and Implant Dentistry)

► Show Figures

Figure 1

Open AccessArticle

Which Histometric Analysis Approach Is More Reliable for Assessing Histological Bone Tissue Samples?

Rodrigo dos Santos Pereira

Carlos Fernando Mourão

Jadson Júnior Conforte

Geraldo Luiz Griza

João Paulo Bonardi

and

Eduardo Hochuli-Vieira

Medicina 2022, 58(10), 1364; https://doi.org/10.3390/medicina58101364 - 28 Sep 2022

Viewed by 1098

Abstract

This study aims to evaluate the grid of Merz and ImageJ methods for histometric quantification, verifying which is more reliable and defining which is most suitable based on the time required to perform. Thirty histological samples of maxillary sinuses grafted with xenografts were evaluated using an optical light microscope attached to an image capture camera and connected to a microcomputer. The images were digitalized and recorded as a TIFF image, and the new bone formation was evaluated using the grid of Merz and ImageJ. The Bland–Altman analysis was used to identify the agreement between the methods and determine suitable future research options. The timing of the quantification was also performed to identify a possible advantage. The mean value for the quantification analysis timing for the grid of Merz was 194.9 ± 72.0 s and for ImageJ was 871.7 ± 264.4, with statistical significance between the groups (p = 0.0001). The Bland–Altman analysis demonstrated a concordance between the methods, due to the bias being next to the maximum concordance (−1.25) in addition to the graphic showing the scattering points next to the mean of differences and inside of limits of agreement. Thus, it was demonstrated that the grid of Merz presents reliable outcomes and advantages over the ImageJ methodology regarding the time spent to contour the areas of interest. Full article

(This article belongs to the Special Issue Advances in Oral Surgery and Implant Dentistry)

► Show Figures

Figure 1

Open AccessArticle

Evaluating Soft Tissue Healing after Implant Placement Using Two Different Mouthwashes (Myrrh and Chlorhexidine Gluconate): A Randomized Control Trial

and

Medicina 2022, 58(10), 1351; https://doi.org/10.3390/medicina58101351 - 26 Sep 2022

Viewed by 1341

Abstract

The use of mouthwash is often recommended by dental experts for dental healing. A double-blind, randomized clinical study was conducted to evaluate the efficacy of two mouthwashes (myrrh and chlorhexidine gluconate) on postoperative pain and their effects on tissues after dental implant placement in 35 patients (18 in the myrrh group and 17 in the chlorhexidine gluconate group). Soft tissue healing was evaluated in terms of wound closure, soft tissue swelling, and the color of the gingiva at 1 week postoperative. To decrease the chances for error, only the participants who did not show preoperative symptoms of infection and those who committed to practicing better oral hygiene were included in the study. The samples were evaluated for the infiltration of inflammatory cells (using inflammatory extent and inflammatory cellularity grades), maturation of collagen (osteoblast activity), and arrangement of cells (for detecting the remodeling phase). A questionnaire pertaining to mouthwash satisfaction, the duration of postoperative pain after the procedure, the time of stoppage of bleeding at the surgical site, and any sensitivity at the surgical site was given to the patients. The Chi-square test and Mann–Whitney U-test were used to analyze the data. The difference in postoperative surgical swelling, pain, bleeding, and redness in the patients was not statistically significant between the myrrh and chlorhexidine gluconate mouthwash groups. However, in the acute phase, the myrrh mouthwash showed a positive impact on the process of wound healing after implant placement. The small sample size and inability to compare wound healing in different anatomical areas of the oral cavity were the study limitations. Full article

(This article belongs to the Special Issue Advances in Oral Surgery and Implant Dentistry)

► Show Figures

Figure 1

Review

Jump to: Research, Other

Open AccessReview

The Use of Human Amniotic Membrane (hAM) as a Treatment Strategy of Medication-Related Osteonecrosis of the Jaw (MRONJ): A Systematic Review and Meta-Analysis of the Literature

Monica Diuana Calasans-Maia

Massimo Maranzano

and

Sergio Olate

Medicina 2023, 59(5), 968; https://doi.org/10.3390/medicina59050968 - 17 May 2023

Viewed by 908

Abstract

Background and objectives: Although it is very uncommon, medication-induced osteonecrosis of the jaw (also known as MRONJ) can have serious consequences. Traditionally, this adverse event has been recognised in patients who were treated with bisphosphonate (BP) drugs. Nevertheless, in recent years, it has been established that individuals having treatment with various types of medications, such as a receptor activator of nuclear factor kappa-Β ligand inhibitor (denosumab) and antiangiogenic agents, have had the same issue. The purpose of this research is to determine if the application of human amniotic membrane (hAM) may be used as a therapy for MRONJ. Material and Methods: A multi-source database (MEDLINE, EMBASE, AMED, and CENTRAL) systematic search was performed. The major objective of this study is to obtain an understanding of the efficacy of hAM when it is employed as a treatment modality for MRONJ. The protocol of this review was registered in the INPLASY register under the number NPLASY202330010. Results: The authors were able to include a total of five studies for the quality analysis, whereas for the quantity evaluation, only four studies were eligible. A total of 91 patients were considered for the investigation. After treatment with human amniotic membrane (hAM), a recurrence of osteonecrosis was observed in n = 6 cases (8.8%). The combined efficacy of surgical therapy and the use of hAM resulted in an overall success rate of 91.2%. Intraoperative complications were only documented in one article, and they were mostly caused by the positioning of the hAM, which led to wound breakdown at the surgical site. Conclusions: Based on the small amount of data and low-quality research included in this study, using human amniotic membranes to treat MRONJ might represent a feasible option. Nevertheless, further studies with a wider patient population are required to understand the long-term impacts. Full article

(This article belongs to the Special Issue Advances in Oral Surgery and Implant Dentistry)

► Show Figures

Figure 1

Other

Jump to: Research, Review

Open AccessCase Report

Regeneration of Horizontal Bone Defect in Edentulous Maxilla Using the Allogenic Bone-Plate Shell Technique and a Composite Bone Graft—A Case Report

and

Medicina 2023, 59(3), 494; https://doi.org/10.3390/medicina59030494 - 02 Mar 2023

Viewed by 1329

Abstract

An insufficient volume of the alveolar bone may prevent implants from being placed in the prosthetically optimal position. Complex restoration of bony structures is required to achieve long-term peri-implant bone stability and represents an adequate prosthetic solution. Background and Objectives: The shell technique has become a widespread and important method for guided bone regeneration in dentistry. Allogeneic bone materials appear to be the most similar substitution for autogenous bone transplants. However, there are few studies using cortical bone allografts in combination with a mix of autogenous and xenograft materials for the augmentation of horizontal ridge defects. This combination offers the advantage of reduced patient morbidity while adding adequate volume and contour to the alveolar ridge. Case report: The present case study aimed to clinically and radiographically evaluate the efficacy of allogenic cortical bone lamina combined with a composite bone graft in the augmentation of a horizontal bone defect in the edentulous maxilla during a 6-year follow-up period. Three CB CT scans taken before treatment, 6 months after the augmentation period/before implant placement, and after a 6-year follow-up period, were analyzed using stable referent points. After the 6 -year follow-up period, the average resorption rate was 21.65% on the augmented buccal side, with no implant exposure being observed. Conclusions: The bone shell technique used in conjunction with allogenic bone plates combined with autogenous bone, xenografts, and collagen membranes is an effective technique to manage horizontal ridge defects. Full article

(This article belongs to the Special Issue Advances in Oral Surgery and Implant Dentistry)

► Show Figures

Figure 1

Open AccessCase Report

Digital Workflow for Implant Placement and Immediate Chairside Provisionalization of a Novel Implant System without Abutment—A Case Report

and

Medicina 2022, 58(11), 1612; https://doi.org/10.3390/medicina58111612 - 08 Nov 2022

Cited by 1 | Viewed by 2324

Abstract

Dental implants have been placed millions of times worldwide, and the surgical procedure and implant design have steadily improved. The basic prosthetic connection, which makes use of an abutment, has changed little over the past decades. These days, implant placement with immediate provisionalization is an essential stage in implant dentistry and interdisciplinary treatment strategies. Temporary computer-aided design and computer-aided manufacturing (CAD/CAM) of implant-supported crowns restore esthetics and guarantee function during the restoration process and the osseointegration of the dental implant. This case report describes the digital planning; the immediate, static, computer-assisted implant surgery, and the immediate chairside provisionalization of a novel implant system that is directly screw-retained without an abutment. Full article

(This article belongs to the Special Issue Advances in Oral Surgery and Implant Dentistry)

► Show Figures

Figure 1

Journal Menu

Journal Browser

Special Issue "Advances in Oral Surgery and Implant Dentistry"

Share This Special Issue

Special Issue Editor

Special Issue Information

Keywords

Published Papers (11 papers)

Research

Review

Other

Further Information

Guidelines

MDPI Initiatives

Follow MDPI