The cytochrome P450-mediated Phase I in vitro metabolism of CRV431 was studied using selective chemical inhibition and recombinant human enzymes. Additionally, the metabolic profile of CRV431 in human, rat, and monkey liver microsomes was investigate...
In this study, we detect and track extratropical cyclones using 6-hourly mean sea level pressure data taken from the Twentieth Century Reanalysis version 3 (20CRv3) over the period 1951–2015 and compare them with those in the Interim and fifth...
51CrV4 steel is extensively used in large-size damping springs for trains and vehicles. Quenching conditions play an important role in performance enhancement. The present work investigated the effects of various oil-bath temperatures and out-of-oil...
In this paper, the effects of the fatigue crack initiation position (FCIP) on fatigue life are discussed. Different modified gradient fields (MGFs) are prepared on the surface of 51CrV4 spring steel components by an ultrasonic assisted surface rollin...
Background: Canine coronavirus (CCoV), canine rotavirus (CRV), canine parvovirus (CPV), and canine distemper virus (CDV) cause gastroenteritis in dogs, and co-infections of these pathogens are common in China. In particular, CCoV and CRV are confirme...
The output of the network in a deep learning (DL) based single-user signal detector, which is a normalized 2 × 1 class score vector, needs to be transmitted to the fusion center (FC) by occupying a large amount of the communication channel (CCH) band...
Chromium (VI) is carcinogenic through intermediates formed in the cellular milieu by reduction with small reductants like glutathione (GSH), ascorbate, cysteine, and NADPH. Although the reduction of chromate by thiols has been investigated, the parti...
The influence of austenitisation temperature and time on the martensitic and isothermal bainite transformation of 51CrV4 spring steel was analysed. Based on the analysis of dilatometric curves, the martensite start temperatures (MS) were determined a...
The working load on automotive components is continuously rising, and the mechanical performance requirements for component materials are rising along with the growth trend toward light weight and high dependability in automobiles. In this study, the...
Cr/V multilayer mirrors are suitable for applications in the “water window” spectral ranges. To study factors influencing the internal microstructure of Cr/V multilayers, multilayers with different vanadium layers thicknesses varying from...
Leaf springs are components of railway rolling stock made of high-strength alloyed steel to resist loading and environmental conditions. Combining the geometric notches with the high surface roughness of its leaves, fatigue models based on local appr...
The powder-pack boriding technique with an open retort was used to form borided layers on X165CrV12 tool steel. The process was carried out at 1123, 1173, and 1223 K for 3, 6, and 9 h. As a result of boriding the high-chromium substrate, the produced...
A crossing nose is a component of railway infrastructure subject to very severe loading conditions. Depending on the severity of these loads, the occurrence of structural fatigue, severe plastic deformation, or rolling fatigue may occur. Under fatigu...
Parabolic leaf springs are components typically found in suspensions of freight railway rolling stock. These components are produced in high-strength alloyed steel, DIN 51CrV4, to resist severe loading and environmental conditions. Despite the materi...
The longevity of railway vehicles is an important factor in their mechanical and structural design. Fatigue is a major issue that affects the durability of railway components, and therefore, knowledge of the fatigue resistance characteristics of crit...
The early diagnosis of infectious diseases is demanded by digital healthcare systems. Currently, the detection of the new coronavirus disease (COVID-19) is a major clinical requirement. For COVID-19 detection, deep learning models are used in various...
The principle of symmetry is one of the general methodological principles of science. The effects of any external influences, such as deformation, stresses, temperature, etc., could lead to the anisotropy (asymmetry) of properties in constructional m...
The mechanical and structural design of railway vehicles is heavily influenced by their lifetime. Because fatigue is a significant factor that impacts the longevity of railway components, it is imperative that the fatigue resistance properties of cru...
The longevity of railway vehicles is an important factor in their mechanical and structural design. Fatigue is a major issue that affects the durability of railway components, and, therefore, knowledge of the fatigue resistance characteristics of cri...
51CrV4 spring steel is a martensitic steel grade that is heat treated by quenching and tempering. Therefore, austenitisation is an important step that influences steel properties. The main goal of austenitisation is to obtain a single-phase austenite...
The presence of MgO·Al2O3 inclusions in 51CrV4 spring steel is detrimental to the alloy’s castability and fatigue properties. To effectively suppress these inclusions during production, accretions were collected from the immersion nozzle...
(1) Background: Tuberculosis (TB) in humans is a serious chronic epidemic disease caused by Mycobacterium tuberculosis (M. tb). The diagnosis of TB, especially extra-pulmonary TB (EPTB), is difficult. Isolation of M. tb from culture has a low sensiti...
Crocodilepox virus (CRV) belongs to the Poxviridae family and mainly infects hatchling and juvenile Nile crocodiles. Most poxviruses encode inhibitors of the host antiviral protein kinase R (PKR), which is activated by viral double-stranded (ds) RNA...
Walking has been studied extensively in recent years. However, one is still hard pressed to find research examining what makes urban settings of different sizes across the Atlantic Ocean conducive to walking, especially in the presence of greenways a...
This article presents the results of experimental investigations conducted to explain the causes of premature failure of two leaves of a semi-elliptical leaf spring mounted in a four-axle heavy-duty truck. The primary intended use of the vehicle was...
Calendula officinalis, Ribes nigrum, and Vaccinium myrtillus (CRV) possess a high phenolic compound content with excellent antioxidant activity. Dietary antioxidants can reduce exercise-induced oxidative stress. Consumption of large amounts of phenol...
Carvedilol (CRV) is a non-selective blocker of α and β adrenergic receptors, which has been extensively used for the treatment of hypertension and congestive heart failure. Owing to its poor biopharmaceutical properties, CRV has been incor...
As part of our continuous effort to find potential anti-inflammatory agents from endophytic fungi, a Fusarium solani strain, isolated from the plant Aponogeton undulatus Roxb., was investigated. Cerevisterol (CRVS) was identified from endophytic fung...
Nonalcoholic fatty liver disease (NAFLD) associated with high-fat diet (HFD) intake involves oxidative stress, inflammation, apoptosis, and genotoxicity. Carvacrol, a natural monoterpenoid phenol, exhibits potent antioxidant, anti-inflammatory, and c...
We investigated the proportions of mono vs. mixed infections for human metapneumovirus (hMPV) as compared to adenovirus (ADV), four types of coronavirus (CRV), parainfluenza virus (PIV), RSV, and enterovirus/rhinovirus (ERV) in Alberta, Canada. Using...
Despite a plethora of studies demonstrating significant morbidity and mortality due to community-acquired respiratory viral (CRV) infections in intensively treated hematology patients, and despite the availability of evidence-based guidelines for the...
Carvedilol (CRV) is a non-selective third generation beta-blocker used to treat hypertension, congestive heart failure and angina pectoris. Oral administration of CRV showed poor bioavailability (25%), which might be ascribed to its extensive first-p...
Uncontrolled proliferation and death resistance are two hallmarks of cancer cells. Breast cancer (BC) has the highest incidence and mortality in women worldwide and national; subtype triple negative (TN) is the most aggressive type because it is not...
The use of amorphous drug delivery systems is an attractive approach to improve the bioavailability of low molecular weight drug candidates that suffer from poor aqueous solubility. However, the pharmaceutical performance of many neat amorphous drugs...
The aim of this research was to prepare an antifungal soybean protein concentrate (SPC) adhesive containing carvacrol (CRV) as a bioactive agent able to delay the attack of molds and yeast during storage of SPC adhesive at 4 °C as water-based systems...
This study examined the potential use of three bacterial strains—Paraburkholderia sp. strain CRV74, Pseudomonas sp. strain CRV21, and Acinetobacter sp. strain CRV19—as biocontrol agents of Botrytis cinerea in grapevine. These strains were...
Saltwater crocodilepox virus (SwCRV), belonging to the genus Crocodylidpoxvirus, are large DNA viruses posing an economic risk to Australian saltwater crocodile (Crocodylus porosus) farms by extending production times. Although poxvirus-like particle...
The objective of the current study was to fabricate a thermosensitive in situ gelling system for the ocular delivery of carvedilol-loaded spanlastics (CRV-SPLs). In situ gel formulations were prepared using poloxamer analogs by a cold method and was...
Currently, Zambia is the second largest source of emeralds, after Colombia. In this study, emerald samples from the Zambian Kamakanga deposit were examined by UV-Vis-NIR, Miro-FTIR, Diamond ViewTM, and LA-ICP-MS. Representative UV-Vis-NIR spectra sho...
As is the case elsewhere in the world, water governance in Ethiopia is a by-product of a complex set of various global and local socio-political, economic, and ecological discourses and narratives. However, the many competitive and often conflicting...
Proper torque is an important element of orthodontic treatment. There are many factors affecting effective torque expression, e.g., the interplay between an archwire and a bracket, the precision during bracket positioning, and the morphology of the c...
The objective of this study was to estimate the direct and indirect effects of agricultural, morphological, physiological, and root traits of popcorn lines, under two conditions of water supply: full irrigation (FI) and drought stress (DS). A complet...
The assessment of milk coagulation properties (MCPs) is crucial for enhancing goat cheese production and quality. In this study, 501 bulk goat milk samples were collected from various farms to evaluate the MCPs. Traditionally, cheesemaking aptitude i...
This pre-clinical study investigated the transient receptor potential ankyrin-1 (TRPA1) channels on modulating targets for glucose homeostasis using agonists: the electrophilic agonists, cinnamaldehyde (CIN) and allyl isothiocyanate (AITC), and the n...
Background: Accurate estimation of mortality is essential for effective public health planning, policymaking, and monitoring of health interventions. In Ghana, multiple data sources are used to estimate mortality, including civil registration systems...
We studied whether myo-inositol supplementation throughout lactation, alone and combined with leptin, may reverse detrimental effects on hypothalamic structure and function caused by gestational calorie gestation (CR) in rats. Candidate early transcr...
Background: We investigate novel OCT parameters, based on the volumetric analysis of lamellar macular holes (LMHs), as prognostic indicators for visual outcomes after surgery. Methods: LMHs were divided into degenerative LMHs (D-LMHs) and ERM-foveosc...
The crop production and limited freshwater resources in the Central Rift Valley (CRV) Lake Basin of Ethiopia have been facing pressure from warmer and drier climates. Thus, irrigation with the goal of increasing water use efficiency and the productiv...
The optimization of battery electric vehicles requires advanced high-strength steels that combine ductility and toughness, enabling lightweight leaf spring constructions with improved performance. This study investigates processing optimization by co...
Undigested neutral detergent fiber (uNDF) is becoming more widely recognized as an important fiber fraction in forage quality assessment because it explains a portion of NDF that is inaccessible to digestion in the ruminant digestive system and is, t...
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