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  • Article
  • Open Access
2 Citations
4,188 Views
26 Pages

Three-Dimensional Site Response Analysis of Clay Soil Considering the Effects of Soil Behavior and Type

  • Rania Al-Ahmar,
  • Mayada Al Ahmad Al Kousa,
  • Amjad Al-Helwani and
  • George Wardeh

8 October 2024

To understand changes in bedrock motion at the ground surface, frequency effects, and spatial distribution within the soil, it is important to look at how a site responds to earthquakes. This is important for soil–structure interaction in struc...

(This article belongs to the Collection Recent Advances and Development in Civil Engineering)
  • Article
  • Open Access
6 Citations
2,843 Views
22 Pages

Seismic Site Amplification Characteristics of Makran Subduction Zone Using 1D Non-Linear Ground Response Analysis

  • Hammad Raza,
  • Naveed Ahmad,
  • Muhammad Aaqib,
  • Turab H. Jafri and
  • Mohsin Usman Qureshi

10 February 2025

The Makran Subduction Zone (MSZ) is a tectonic plate boundary where the Arabian Plate is subducting beneath the Eurasian Plate. This study investigated the dynamic response in the Gwadar region, located in the eastern part of the MSZ. A suite of seis...

(This article belongs to the Section Civil Engineering)
  • Article
  • Open Access
1,059 Views
14 Pages

28 May 2025

The mode superposition method has been widely used for the seismic response analysis of two-dimensional (2D) sites to enhance computational efficiency. However, this method lacks a guideline of modal truncation to control errors of acceleration respo...

(This article belongs to the Section Civil Engineering)
  • Article
  • Open Access
3 Citations
2,666 Views
30 Pages

In practice, site-specific one-dimensional (1D) seismic site response analyses are conducted to compute surface acceleration time histories considering shear wave velocity profile, modulus reduction, damping, and site-specific ground motions. The com...

(This article belongs to the Section Natural Hazards)
  • Article
  • Open Access
170 Views
36 Pages

11 October 2026

This study investigates how soil–structure interaction (SSI) affects the seismic effectiveness and relative performance of high-strength masonry infill retrofit layouts for a three-story nonductile reinforced concrete building. Three retrofit c...

(This article belongs to the Section Civil Engineering)
  • Article
  • Open Access
38 Citations
9,422 Views
27 Pages

The city of Ivanec is located between valley of the Bednja River and Mt. Ivanščica and this area can be prone to significant seismic site amplification due to local site characteristics. This study presents the first assessment of seismic site...

(This article belongs to the Special Issue Seismic Sequence in Mediterranean Region)
  • Article
  • Open Access
3 Citations
3,203 Views
23 Pages

2-D Seismic Response Analysis of a Slope in the Tyrrhenian Area (Italy)

  • Antonio Cavallaro,
  • Antonio Ferraro,
  • Salvatore Grasso and
  • Antonio Puccia

2 April 2021

The Caronia area is located in the Tyrrhenian north-eastern sector of Sicily (Italy). Starting in 2010, attention focused on the study of landslides phenomena that occurred in this area, which caused significant economic damage to buildings and infra...

(This article belongs to the Special Issue Seismic Geotechnical Hazards Studies)
  • Article
  • Open Access
1 Citations
659 Views
15 Pages

Community Characteristics of Phytoplankton in Dongping Lake Revealed by eDNA and Implications for Water-Quality Assessment

  • Chunmei Leng,
  • Yunfang Gao,
  • Xuri Cong,
  • Lixia Qing,
  • Guojing Xu,
  • Xiaoli Wang,
  • Xiuqi Li,
  • Shiwen Zhu and
  • Guancang Dong

1 April 2026

Dongping Lake is a regulating lake where hydrodynamic alteration and heterogeneous inputs may reshape phytoplankton communities; this study aimed to characterize eukaryotic phytoplankton, assess water quality and identify key environmental drivers. I...

(This article belongs to the Section Biodiversity and Functionality of Aquatic Ecosystems)
  • Article
  • Open Access
15 Citations
6,291 Views
14 Pages

Chlorella has great potential as a bio-factory for production of value-added compounds. To produce the desired chemicals more efficiently in Chlorella, genetic tools for modification of Chlorella need to be developed, especially an endogenous promote...

(This article belongs to the Section Biochemistry)
  • Technical Note
  • Open Access
2 Citations
2,208 Views
12 Pages

19 August 2024

This study focuses on the application of ground-penetrating radar (GPR) in conducting field surveys and data processing at the northern campus of Jilin Jianzhu University. The research site’s geographical location and overall conditions are des...

(This article belongs to the Special Issue Ground Penetrating Radar: Data, Imaging, and Signal Analysis)
  • Article
  • Open Access
6 Citations
3,959 Views
15 Pages

Identification of Olfactory Receptors Responding to Androstenone and the Key Structure Determinant in Domestic Pig

  • Peidong Yang,
  • Tingting Luo,
  • Shuqi Yang,
  • Anjing Zhang,
  • Yuan Tang,
  • Li Chen,
  • Jinyong Wang,
  • Yongju Zhao,
  • Zhining Zhong and
  • Lu Lu
  • + 8 authors

Olfactory receptors (ORs) are members of the transmembrane G protein-coupled receptor superfamily, playing a crucial role in odor recognition, which further mediates crucial biological processes in mammals. In sows, androstenone can trigger sexual be...

(This article belongs to the Section Biochemistry, Molecular and Cellular Biology)
  • Article
  • Open Access
19 Citations
7,553 Views
28 Pages

The integration of site effects into Probabilistic Seismic Hazard Assessment (PSHA) is still an open issue within the seismic hazard community. Several approaches have been proposed varying from deterministic to fully probabilistic, through hybrid (p...

(This article belongs to the Special Issue Site-Specific Seismic Hazard Analysis: New Perspectives, Open Issues and Challenges)
  • Brief Report
  • Open Access
25 Citations
6,921 Views
16 Pages

The Role of Polymorphisms in Vitamin D-Related Genes in Response to Vitamin D Supplementation

  • Sara Tomei,
  • Parul Singh,
  • Rebecca Mathew,
  • Valentina Mattei,
  • Mathieu Garand,
  • Mariam Alwakeel,
  • Elham Sharif and
  • Souhaila Al Khodor

27 August 2020

Background. Vitamin D deficiency represents a major healthcare problem. Vitamin D status is influenced by genetic and environmental determinants. Several observational studies have evaluated the association of single-nucleotide polymorphisms (SNPs) i...

(This article belongs to the Section Micronutrients and Human Health)
  • Article
  • Open Access
398 Views
20 Pages

Tall Urban Tree Canopies May Amplify Low-Altitude UAV Noise: Evidence from Field Measurements and Psychoacoustic Assessment

  • Xurui Lyu,
  • Zhili Yao,
  • Zhiying Lin,
  • Tao Luo,
  • Binghua Zhang,
  • Hui Chen and
  • Xinchen Chester Hong

1 August 2026

The rapid growth of UAV use in urban logistics, infrastructure inspection, emergency response, and campus services has made low-altitude flights more common in residential environments. Previous studies have mainly examined aircraft acoustics, flight...

(This article belongs to the Special Issue Soundscape in Urban Forests—2nd Edition)
  • Article
  • Open Access
385 Views
28 Pages

21 August 2026

Proto-AGI describes the intermediate stage of artificial intelligence between narrow task-specific tools and fully autonomous general intelligence. This paper presents the first formal operationalisation of Proto-AGI traits within a cross-domain digi...

(This article belongs to the Section Building Structures)
  • Article
  • Open Access
64 Citations
10,128 Views
15 Pages

21 July 2021

Photosystem II (PSII) is a multi-subunit enzymatic complex embedded in the thylakoid membranes responsible for the primary photosynthetic reactions vital for plants. Many herbicides used for weed control inhibit PSII by interfering with the photosynt...

(This article belongs to the Section Plant Physiology and Metabolism)
  • Article
  • Open Access
2 Citations
2,806 Views
17 Pages

5 April 2023

When the numerical analysis of a long lined tunnel is carried out, the calculation amount of the finite element model becomes restricted large-scale parameter analysis. In this paper, an efficient and high-precision 2.5-dimensional (2.5D) frequency-d...

(This article belongs to the Special Issue Urban Underground Engineering: Excavation, Monitoring, and Control)
  • Article
  • Open Access
2 Citations
2,798 Views
18 Pages

9 December 2022

In the seismic response analysis of liquefiable sites, the existing soil dynamic constitutive model is challenging to simulate saturated sand’s post-liquefaction deformation, and the current pore-water pressure buildup model cannot reflect the...

(This article belongs to the Special Issue Earthquake Engineering Technology and Its Application)
  • Article
  • Open Access
2 Citations
2,314 Views
19 Pages

Exploring the Application of NeRF in Enhancing Post-Disaster Response: A Case Study of the Sasebo Landslide in Japan

  • Jinge Zhang,
  • Yan Du,
  • Yujing Jiang,
  • Sunhao Zhang,
  • Hongbin Chen and
  • Dongqi Shang

Rapid acquisition of 3D reconstruction models of landslides is crucial for post-disaster emergency response and rescue operations. This study explores the application potential of Neural Radiance Fields (NeRF) technology for rapid post-disaster site...

(This article belongs to the Topic Geotechnics for Hazard Mitigation)
  • Article
  • Open Access
1 Citations
2,242 Views
17 Pages

10 December 2023

In this study, dynamic numerical analysis was conducted on the existing sound barrier wall structure and the recently developed double-sided solar-module-integrated sound barrier wall structure using the finite-difference method for numerical modelin...

(This article belongs to the Section Building Energy, Physics, Environment, and Systems)
  • Systematic Review
  • Open Access
893 Views
15 Pages

Efficacy and Safety of Intralesional Purified Protein Derivative Versus Vitamin D for the Treatment of Cutaneous Warts: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • Ahmed Abu-Zaid,
  • Samira Hilali,
  • Zainab Albasheer,
  • Shouq Alkhatlan,
  • Fanr F. Alraqum,
  • Abdulmuhsin H. Al-Rashid,
  • Malak A. Alshamali,
  • Faisal Fahad AlSuwailem,
  • Abdullah N. Almutairi and
  • Abdullah M. Alharran
  • + 1 author

7 May 2026

Background: Cutaneous warts, caused by HPV, are common, and conventional destructive treatments often fail to prevent recurrence. Intralesional immunotherapy offers a promising alternative. Specifically, purified protein derivative (PPD) and vitamin...

(This article belongs to the Section Dermatology)
  • Article
  • Open Access
1 Citations
2,123 Views
13 Pages

Changes in DNA Methylation and mRNA Expression in Lung Tissue after Long-Term Supplementation with an Increased Dose of Cholecalciferol

  • Alicja Wierzbicka,
  • Ewelina Semik-Gurgul,
  • Małgorzata Świątkiewicz,
  • Tomasz Szmatoła,
  • Anna Steg and
  • Maria Oczkowicz

29 December 2023

Maintaining an appropriate concentration of vitamin D is essential for the proper functioning of the body, regardless of age. Nowadays, there are more and more indications that vitamin D supplementation at higher than standard doses may show protecti...

(This article belongs to the Section Molecular Genetics and Genomics)
  • Article
  • Open Access
7 Citations
5,288 Views
15 Pages

19 March 2020

The modified vaccinia virus Ankara (MVA), a severely attenuated strain of vaccinia virus, is a promising vector platform for viral-vectored vaccine development because of its attributes of efficient transgene expression and safety profile, among othe...

(This article belongs to the Special Issue Genomic Medicine and Advances in Vaccine Technology and Development in the Developing and Developed World)
  • Article
  • Open Access
1 Citations
3,120 Views
24 Pages

Seismic Microzonation Map for a Fixed-Jacket Platform in the Malay Basin

  • Mohamad Mazlina,
  • M. S. Liew,
  • Kamaluddeen Usman Danyaro,
  • Azlan Adnan and
  • Nor Hayati Ab Hamid

14 September 2022

The existence of soft soil in offshore areas may lead to the amplification of vibration received from offshore facilities, especially from the existing fixed-jacket platforms, which were designed without provision to seismicity, as in Malaysian water...

  • Review
  • Open Access
24 Citations
10,621 Views
15 Pages

The first step for learning any calculation code for seismic response analysis is an adequate understanding of how to properly set the boundary conditions and the properties of the soil model at the initial stage, i.e., before the shaking event. To p...

(This article belongs to the Section Natural Hazards)
  • Article
  • Open Access
10 Citations
5,754 Views
17 Pages

Analysis of the Molecular Interactions between Cytochromes P450 3A4 and 1A2 and Aflatoxins: A Docking Study

  • Isui Abril García-Montoya,
  • Norma Rosario Flores-Holguín,
  • Linda-Lucila Landeros-Martínez,
  • Mónica Alvarado-González,
  • Quintín Rascón-Cruz,
  • María Elena Fuentes-Montero,
  • Pedro Palomares-Báez and
  • Luz María Rodríguez-Valdez

17 June 2019

Mycotoxins known as aflatoxins (AF) are produced as a secondary metabolite by some species of Aspergillus fungi. They are considered carcinogenic, hepatotoxic, teratogenic, and mutagenic. In this study, the molecular structure, chemical reactivity, a...

(This article belongs to the Section Applied Biosciences and Bioengineering)
  • Article
  • Open Access
8 Citations
2,627 Views
15 Pages

Modelling and Stability Assessment of the Rock Cliffs and Xrobb l-Ġħaġin Neolithic Structure in Malta

  • George Volanis,
  • Demitrios Galanakis,
  • Nikolaos Bolanakis,
  • Emmanuel Maravelakis,
  • Ruben Paul Borg and
  • Georgios E. Stavroulakis

3 June 2024

The stability of rock cliffs is a longstanding issue and is of practical significance. This case study demonstrates the application and use of advanced 3D modeling techniques, concentrating on the geological formations of the Xrobb l-Ġħa...

  • Article
  • Open Access
3 Citations
2,628 Views
14 Pages

Low temperatures are the most significant abiotic stressor for the conservation and production of Phalaenopsis in non-tropical areas. CBF/DREB1 transcription factors play an important role in the plant abiotic stress response. In this study, 31 DREB...

(This article belongs to the Special Issue Abiotic Stress Responses in Ornamental Crops: The State of the Art 2024)
  • Article
  • Open Access
9 Citations
5,281 Views
25 Pages

3 September 2021

Site amplification factors in National Building Codes are typically specified as a function of the average shear wave velocity over the first 30 m (Vs30) or site class (A, B, C, D and E) for defined ranges of Vs30 and/or ranges of depth to bedrock. H...

  • Article
  • Open Access
27 Citations
5,322 Views
23 Pages

Sequence Deep Learning for Seismic Ground Response Modeling: 1D-CNN, LSTM, and Transformer Approach

  • Yongjin Choi,
  • Huyen-Tram Nguyen,
  • Taek Hee Han,
  • Youngjin Choi and
  • Jaehun Ahn

30 July 2024

Accurate seismic ground response analysis is crucial for the design and safety of civil infrastructure and establishing effective mitigation measures against seismic risks and hazards. This is a complex process due to the nonlinear soil properties an...

(This article belongs to the Special Issue Smart Geotechnical Engineering)
  • Feature Paper
  • Article
  • Open Access
15 Citations
8,868 Views
11 Pages

26 April 2022

Human lysozyme is a natural non-specific immune protein that participates in the immune response of infants against bacterial and viral infections. Lysozyme is a well-known hydrolase that cleaves peptidoglycan in bacterial cell walls. Several crystal...

(This article belongs to the Special Issue Enzyme Catalysis: Advances, Techniques, and Outlooks)
  • Article
  • Open Access
12 Citations
7,003 Views
20 Pages

The Leaning Tower of Pisa was built between 1173 and 1360 and began to lean at the beginning of its construction. Extensive investigations to reveal the causes of the tilting only began in the early 20th century. Although few earthquakes have been re...

(This article belongs to the Special Issue Site-Specific Seismic Hazard Analysis: New Perspectives, Open Issues and Challenges)
  • Article
  • Open Access
1,404 Views
21 Pages

Salinity is one of the major factors limiting the growth, development, and yield of cotton. Although the mechanisms of cotton tolerance to salt stress have been studied, the regulatory roles and mechanisms of protein kinases and phosphatases in cotto...

(This article belongs to the Section Molecular Plant Sciences)
  • Article
  • Open Access
659 Views
14 Pages

A Novel Mutation in Maize D1 (Dwarf 1) Confers a Severe Dwarf Phenotype

  • Bingpeng Yang,
  • Yanhui Wang,
  • Yufei Teng,
  • Yan Liu,
  • Xinjun Fan,
  • Qianrui Yang,
  • Na Li,
  • Binwen Shi,
  • Wanchao Zhu and
  • Jiquan Xue
  • + 2 authors

Plant height is a fundamental quantitative phenotypic trait affecting maize (Zea mays) planting density and is an important focus in the breeding of varieties suitable for mechanical harvesting. In this study, we found a natural extreme dwarf mutant...

(This article belongs to the Section Molecular Plant Sciences)
  • Article
  • Open Access
5 Citations
1,548 Views
17 Pages

Curli fimbriae are a major component of biofilm formation in Escherichia coli, and their expression is regulated by numerous transcription factors and small regulatory RNAs (sRNAs). The RcsD-RcsC-RcsB phosphorelay system, which is involved in the env...

(This article belongs to the Special Issue Transcriptional Regulation in Bacteria, 2nd Edition)
  • Article
  • Open Access
16 Citations
5,235 Views
13 Pages

Antigenic Site Variation in the Hemagglutinin of Pandemic Influenza A(H1N1)pdm09 Viruses between 2009–2017 in Ukraine

  • Oksana Zolotarova,
  • Iryna Budzanivska,
  • Liudmyla Leibenko,
  • Larysa Radchenko and
  • Alla Mironenko

18 October 2019

The hemagglutinin (HA) is a major influenza virus antigen, which, once recognized by antibodies and substitutions in HA genes, helps virus in escaping the human immune response. It is therefore critical to perform genetic and phylogenetic analysis of...

(This article belongs to the Section Human Pathogens)
  • Article
  • Open Access
6 Citations
3,513 Views
17 Pages

Genomic Determinants Potentially Associated with Clinical Manifestations of Human-Pathogenic Tick-Borne Flaviviruses

  • Artem N. Bondaryuk,
  • Nina V. Kulakova,
  • Ulyana V. Potapova,
  • Olga I. Belykh,
  • Anzhelika V. Yudinceva and
  • Yurij S. Bukin

2 November 2022

The tick-borne flavivirus group contains at least five species that are pathogenic to humans, three of which induce encephalitis (tick-borne encephalitis virus, louping-ill virus, Powassan virus) and another two species induce hemorrhagic fever (Omsk...

(This article belongs to the Section Molecular Genetics and Genomics)
  • Article
  • Open Access
16 Citations
5,708 Views
12 Pages

Detailed Evolutionary Analyses of the F Gene in the Respiratory Syncytial Virus Subgroup A

  • Mariko Saito,
  • Hiroyuki Tsukagoshi,
  • Mitsuru Sada,
  • Soyoka Sunagawa,
  • Tatsuya Shirai,
  • Kaori Okayama,
  • Toshiyuki Sugai,
  • Takeshi Tsugawa,
  • Yuriko Hayashi and
  • Hirokazu Kimura
  • + 4 authors

15 December 2021

We performed evolution, phylodynamics, and reinfection-related antigenicity analyses of respiratory syncytial virus subgroup A (RSV-A) fusion (F) gene in globally collected strains (1465 strains) using authentic bioinformatics methods. The time-scale...

(This article belongs to the Special Issue RNA Viruses: Structure, Adaptation, and Evolution)
  • Article
  • Open Access
862 Views
15 Pages

Serotype-Specific Biochemical and Immunological Signatures of Dengue Virus Envelope Proteins

  • Iasmin V. Costa,
  • Ana Cecília R. Cruz and
  • Carlos Alberto M. Carvalho

Dengue is an arboviral disease of global significance caused by Orthoflavivirus denguei (DENV), which has four antigenically distinct serotypes. The envelope (E) protein plays a critical role in viral entry and eliciting immune responses. This study...

(This article belongs to the Section Molecular Microbiology)
  • Article
  • Open Access
433 Views
17 Pages

Weathered marl hillslopes fail repeatedly across peri-urban Morocco, yet engineers investigating them rarely know which soil or geometric property most deserves their limited testing budget. This study answers that question for the landslide-prone sl...

  • Article
  • Open Access
6 Citations
2,885 Views
14 Pages

23 February 2022

Due to the potential applications of transition metal nitrides in modern electronic and spintronic devices, we have systematically studied the magnetic properties of δ-MoN induced by the Mn dopant, with the goal of identifying the origin of mag...

(This article belongs to the Special Issue Nanocomposite Design for Energy-Related Applications)
  • Article
  • Open Access
1,384 Views
20 Pages

Characterization of the Glutamine Synthetase Gene Family in Wheat (Triticum aestivum L.) and Expression Analysis in Response to Various Abiotic Stresses

  • Zhiyong Zhang,
  • Xiaojiao Zhang,
  • Yanling Mu,
  • Huali Wang,
  • Lulu Wang,
  • Furong Nai,
  • Yihao Wei,
  • Shuping Xiong,
  • Xinming Ma and
  • Xiaochun Wang
  • + 1 author

26 September 2025

Glutamine synthetase plays an essential role in regulating plant growth and development. However, few studies have analyzed the roles of TaGS in wheat under abiotic stress conditions. In this study, we identified and analyzed the members of the TaGS...

(This article belongs to the Section Molecular Biology)
  • Article
  • Open Access
9 Citations
4,853 Views
27 Pages

Urban tunnelling can be highly challenging, especially in areas where limited ground settlements and environmental disturbance is required. Mechanised tunnelling is usually preferred in such ground environments, specifically Slurry or EPBM (Earth Pre...

(This article belongs to the Special Issue Advanced Numerical Modelling and Analysis in Geotechnical Engineering)
  • Article
  • Open Access
18 Citations
5,845 Views
18 Pages

Interaction between Saikosaponin D, Paeoniflorin, and Human Serum Albumin

  • Guo-Wu Liang,
  • Yi-Cun Chen,
  • Yi Wang,
  • Hong-Mei Wang,
  • Xiang-Yu Pan,
  • Pei-Hong Chen and
  • Qing-Xia Niu

27 January 2018

Saikosaponin D (SSD) and paeoniflorin (PF) are the major active constituents of Bupleuri Radix and Paeonia lactiflora Pall, respectively, and have been widely used in China to treat liver and other diseases for many centuries. We explored the binding...

(This article belongs to the Collection Herbal Medicine Research)
  • Article
  • Open Access
5 Citations
2,644 Views
22 Pages

16 November 2022

As the hydropower development strategies of China continue to be implemented, a host of large hydropower projects have been completed or are being constructed in southwest China. During construction of the Jinchuan hydropower station, this study exam...

(This article belongs to the Section Earth Sciences)
  • Article
  • Open Access
2 Citations
2,719 Views
22 Pages

25 May 2023

To comprehensively evaluate the seismic performance of offshore bridges, a seismic risk analysis of an example bridge was developed based on improved two-dimensional (2D) seismic fragility analysis. Taking a simply-supported beam bridge in an offshor...

(This article belongs to the Special Issue Geotechnical Earthquake Engineering: Current Progress and Road Ahead)
  • Article
  • Open Access
1 Citations
4,087 Views
12 Pages

28 April 2022

A ditopic nitrogen ligand (E)-N′-(pyridin-4-ylmethylene)isonicotinohydrazide (L) containing both divergent pyridyl coordination sites and a hydrogen-bonding hydrazide–hydrazone moiety was synthesized. The Co(NCS)2-mediated self-assembly o...

(This article belongs to the Special Issue Earth-Abundant Metal Chemistry and Catalysis)
  • Article
  • Open Access
5 Citations
2,778 Views
21 Pages

4 November 2024

In recent years, numerous studies highlighted the crucial role of the soil–structure interaction (SSI) in the seismic performance of basement structures. However, there remains a limited understanding of how this interaction affects buildings w...

(This article belongs to the Special Issue Advances in Soil-Structure Interaction for Building Structures)
  • Article
  • Open Access
6 Citations
3,207 Views
13 Pages

Water shortages around the world have intensified the search for substitute sources. Greywater can serve as a solution for water requirements. Compared to two-dimensional electrochemical processes for water treatment, the addition of particle activat...

  • Article
  • Open Access
13 Citations
6,216 Views
11 Pages

Landslide triggered by earthquake or rainstorm often results in serious property damage and human casualties. It is, therefore, necessary to establish an emergency management system to facilitate the processes of damage assessment and decision-making...

(This article belongs to the Special Issue Advances in Geo-Information for Environmental Forensics and Environmental Risk Management in the Anthropocene)

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