Transcriptional Regulation in Bacteria, 2nd Edition
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Molecular Microbiology and Immunology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 366
Special Issue Editor
Interests: transcription factor; transcriptional regulation; genomic SELEX; RNA polymerase; sigma factor; Escherichia coli; genome regulation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The goal of research in the post-genomic era, now that the full extent of the genes encoded by microbial genomes is known, is to elucidate the whole mechanism by which microorganisms utilize genes through transcriptional regulation. Deciphering the genome sequence of microorganisms has revealed its gene set and the set of transcriptional regulators that regulate those genes, providing a complete overview of transcriptional regulation in microorganisms. The number of target genes depends on the function of the transcription factor; some single-target regulators target a single gene in the genome, while others are global regulators that target hundreds of genes. In some cases, these have been shown to cooperate or antagonize each other at hundreds or more sites on the genome, dynamically regulating gene transcription.
It has also become clear that transcription factors comprehensively regulate multiple genes involved in seemingly unrelated biological functions. Thus, analyses of transcriptional regulation reveal not only the molecular mechanisms of transcriptional regulation but also the functional network of genes, leading to the elucidation of new physiological mechanisms of microorganisms.
This Special Issue aims to collect recent studies on microorganisms, from detailed and precise studies on the transcriptional regulatory mechanisms of single genes, to studies on the genome regulatory networks of whole genes, to newly revealed microorganism mechanisms.
Dr. Tomohiro Shimada
Guest Editor
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Keywords
- transcription
- gene regulation
- genome regulation
- regulatory network
- RNA polymerase
- sigma factor
- transcription factor
- nucleoid
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