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37 Results Found

  • Article
  • Open Access
26 Citations
9,247 Views
15 Pages

Anti-Atopic Effect of Acorn Shell Extract on Atopic Dermatitis-Like Lesions in Mice and Its Active Phytochemicals

  • Sullim Lee,
  • Hyun Jegal,
  • Sim-Kyu Bong,
  • Kyeong-No Yoon and ,
  • No-June Park,
  • Myoung-Sook Shin,
  • Min Hye Yang,
  • Yong Kee Kim and
  • Su-Nam Kim
  • + 4 authors+ 0 author

29 December 2019

To investigate the potential effects of acorn shells on atopic dermatitis (AD), we utilized oxazolone (OX)- or 2,4-dinitrochlorobenzene (DNCB)-induced AD-like lesion mouse models. Our research demonstrates that Acorn shell extract (ASE) improved the...

(This article belongs to the Special Issue Phytochemical Constituents of Medicinal Plants for the Treatment of Chronic Inflammation)
  • Article
  • Open Access
3 Citations
1,722 Views
28 Pages

24 February 2026

Background/Objectives: Stroke is a leading cause of long-term disability, and predicting functional outcome at discharge, such as the modified Rankin Scale (mRS), is important for guiding treatment and rehabilitation. Many existing approaches depend...

(This article belongs to the Special Issue Cutting-Edge Applications: Artificial Intelligence and Deep Learning Revolutionizing CT and MRI)
  • Article
  • Open Access
2 Citations
2,458 Views
12 Pages

Garden Snail Predatory Insects’ Modus Operandi Under Laboratory Conditions

  • Giulia Murgia,
  • Valentina Coroneo,
  • Carlo Zuddas,
  • Sara Maria Pani and
  • Maria Paola Cogoni

5 November 2024

Heliciculture farms are susceptible to significant biotic issues that can impact snail breeding, among them, the entomofauna predation of snails. Predatory insects can cause damage to snail shells during predation, and sometimes, the specific type of...

  • Article
  • Open Access
2 Citations
3,554 Views
13 Pages

The nucleus accumbens shell (NAcSh) is a major structure associated with distinct aspects of reward and mnemonic information encoding, relying on spatial data to define optimal behavioral strategies. Chronic pain-derived striatal plasticity is consid...

(This article belongs to the Special Issue Experimental Biology: From Methods to Applications—Under the Auspices of the Italian Society of Experimental Biology, SIBS-1925)
  • Article
  • Open Access
5 Citations
3,769 Views
13 Pages

Protective Effects of Chestnut (Castanea crenata) Inner Shell Extract in Macrophage-Driven Emphysematous Lesion Induced by Cigarette Smoke Condensate

  • Ji-Soo Jeong,
  • Jeong-Won Kim,
  • Jin-Hwa Kim,
  • Chang-Yeop Kim and ,
  • Je-Won Ko and
  • Tae-Won Kim
  • + 1 author+ 0 author

4 January 2023

Chestnut (Castanea crenata) inner shell extract (CIE), a curative herb in Korea, has diverse pharmacological effects against various diseases including pulmonary fibrosis, asthma, and chronic obstructive pulmonary disease (COPD). However, its molecul...

(This article belongs to the Section Phytochemicals and Human Health)
  • Article
  • Open Access
1 Citations
3,136 Views
11 Pages

26 June 2024

Background and Objectives: Peri-acetabular metastases often lead to significant pain and functional impairment. Surgical interventions, including the Harrington procedure, aim to address these challenges. This study evaluates a modified Harrington pr...

(This article belongs to the Special Issue Trends and Developments in Hip and Knee Arthroplasty Technology)
  • Communication
  • Open Access
4 Citations
2,784 Views
8 Pages

Evaluation of Mud Worm (Polydora spp.) Infestation in Cupped (Crassostrea gigas) and Flat Oyster (Ostrea edulis) Broodstocks: Comparison between Magnetic Resonance Imaging and Computed Tomography

  • Livio Galosi,
  • Fabrizio Dini,
  • Marina C. T. Meligrana,
  • Lorenzo Gennari and ,
  • Elena Tamburini and
  • Alessandra Roncarati
  • + 1 author+ 0 author

12 January 2024

The Polichete worms of the genus Polydora are considered very destructive for oysters, excavating channels in their shell and inducing oysters to create mud blisters in response to the irritation, interfering with their physiology and ethology. The p...

  • Review
  • Open Access
25 Citations
8,093 Views
14 Pages

The Emerging Role of Ferumoxytol-Enhanced MRI in the Management of Cerebrovascular Lesions

  • Nohra Chalouhi,
  • Pascal Jabbour,
  • Vincent Magnotta and
  • David Hasan

13 August 2013

Inflammation is increasingly being understood to be a key component to the pathophysiology of cerebrovascular lesions. Ferumoxytol, an iron oxide nanoparticle coated by a carbohydrate shell, has been used in MRI studies as an inflammatory marker beca...

  • Review
  • Open Access
56 Citations
9,752 Views
40 Pages

Wound Dressing with Electrospun Core-Shell Nanofibers: From Material Selection to Synthesis

  • Nariman Rajabifar,
  • Amir Rostami,
  • Shahnoosh Afshar,
  • Pezhman Mosallanezhad and ,
  • Payam Zarrintaj,
  • Mohsen Shahrousvand and
  • Hossein Nazockdast
  • + 2 authors+ 0 author

5 September 2024

Skin, the largest organ of the human body, accounts for protecting against external injuries and pathogens. Despite possessing inherent self-regeneration capabilities, the repair of skin lesions is a complex and time-consuming process yet vital to pr...

(This article belongs to the Special Issue Electrospun Nanofibers: Current Advances and Future Perspective)
  • Article
  • Open Access
1 Citations
3,866 Views
13 Pages

Enhanced Cell Inactivation and Double-Strand Break Induction in V79 Chinese Hamster Cells by Monochromatic X-Rays at Phosphorus K-Shell Absorption Peak

  • Teruaki Konishi,
  • Daichi Yoshihara,
  • Munetoshi Maeda,
  • Daisuke Ohsawa and ,
  • Noriko Usami and
  • Kotaro Hieda
  • + 1 author+ 0 author

The cell inactivation and DNA double-strand break (DSB) induction by K-shell ionization of phosphorus atoms and Auger electrons were investigated. Monochromatic X-rays of on and below the phosphorus K-shell absorption peak, 2.153 keV and 2.147 keV we...

(This article belongs to the Special Issue Advanced Synchrotron Radiation as a Quantum Tool for Exploring Deep Life Sciences)
  • Article
  • Open Access
3 Citations
2,205 Views
30 Pages

Multifunctional Fe3O4@ZIF-8 Nanoparticles with Antibiosis and Osteogenesis for Treatment of Jaw Osteomyelitis

  • Heng Li,
  • Zhiyue Zhang,
  • Yu Wang,
  • Ting Mou and ,
  • Jiaqi Tian,
  • Chong Huang,
  • Lu Zhao,
  • Zeyang Ge,
  • Dandan Wang and
  • Chunlin Zong
  • + 9 authors+ 4 authors

Background/Objectives: Jaw osteomyelitis (OM) is a refractory purulent inflammation caused by bacterial infection, characterized by persistent infection, excessive bone resorption, and resultant bone defects. Currently, mainstream therapies for jaw O...

(This article belongs to the Section Nanomedicine and Nanotechnology)
  • Feature Paper
  • Article
  • Open Access
10 Citations
4,345 Views
16 Pages

Noble Pen Shell (Pinna nobilis) Mortalities along the Eastern Adriatic Coast with a Study of the Spreading Velocity

  • Željko Mihaljević,
  • Željko Pavlinec,
  • Ivana Giovanna Zupičić,
  • Dražen Oraić and ,
  • Aleksandar Popijač,
  • Osvin Pećar,
  • Ivan Sršen,
  • Miroslav Benić,
  • Boris Habrun and
  • Snježana Zrnčić
  • + 5 authors+ 0 author

Noble pen shells (Pinna nobilis) along the Eastern Adriatic coast were affected by mass mortalities similarly to the populations across the Mediterranean basin. Samples of live animals and organs originating from sites on Mljet Island on the south an...

(This article belongs to the Special Issue Microbial Diseases of Marine Organisms)
  • Article
  • Open Access
18 Citations
4,602 Views
17 Pages

A Unique Core–Shell Structured, Glycol Chitosan-Based Nanoparticle Achieves Cancer-Selective Gene Delivery with Reduced Off-Target Effects

  • Bei Cheng,
  • Hye-Hyun Ahn,
  • Hwanhee Nam,
  • Zirui Jiang and ,
  • Feng J. Gao,
  • Il Minn and
  • Martin G. Pomper
  • + 2 authors+ 0 author

The inherent instability of nucleic acids within serum and the tumor microenvironment necessitates a suitable vehicle for non-viral gene delivery to malignant lesions. A specificity-conferring mechanism is also often needed to mitigate off-target tox...

(This article belongs to the Special Issue Nanoparticle Delivery to Tumors: Challenges and Advances)
  • Article
  • Open Access
8 Citations
4,232 Views
18 Pages

Synthesis of Radioluminescent CaF2:Ln Core, Mesoporous Silica Shell Nanoparticles for Use in X-ray Based Theranostics

  • Hayden Winter,
  • Megan J. Neufeld,
  • Lydia Makotamo,
  • Conroy Sun and
  • Andrea M. Goforth

24 July 2020

X-ray radiotherapy is a common method of treating cancerous tumors or other malignant lesions. The side effects of this treatment, however, can be deleterious to patient quality of life if critical tissues are affected. To potentially lower the effec...

(This article belongs to the Special Issue Nanopharmaceutics)
  • Article
  • Open Access
19 Citations
3,495 Views
15 Pages

Contrast-Enhanced Ultrasound in Distinguishing between Malignant and Benign Peripheral Pulmonary Consolidations: The Debated Utility of the Contrast Enhancement Arrival Time

  • Carla Maria Irene Quarato,
  • Beatrice Feragalli,
  • Donato Lacedonia,
  • Gaetano Rea and ,
  • Giulia Scioscia,
  • Evaristo Maiello,
  • Concetta Di Micco,
  • Cristina Borelli,
  • Antonio Mirijello and
  • Marco Sperandeo
  • + 8 authors+ 3 authors

10 February 2023

Background. Limited studies and observations conducted on a too small number of patients prevent determining the actual clinical utility of pulmonary contrast-enhanced ultrasound (CEUS). The aim of the present study was to examine the efficacy of con...

(This article belongs to the Special Issue Advances in Chest Imaging Diagnostics)
  • Article
  • Open Access
21 Citations
4,537 Views
19 Pages

Docosahexaenoic Acid-Loaded Polylactic Acid Core-Shell Nanofiber Membranes for Regenerative Medicine after Spinal Cord Injury: In Vitro and In Vivo Study

  • Zhuo-Hao Liu,
  • Yin-Cheng Huang,
  • Chang-Yi Kuo,
  • Chao-Ying Kuo and ,
  • Chieh-Yu Chin,
  • Ping K. Yip and
  • Jyh-Ping Chen
  • + 2 authors+ 0 author

24 September 2020

Spinal cord injury (SCI) is associated with disability and a drastic decrease in quality of life for affected individuals. Previous studies support the idea that docosahexaenoic acid (DHA)-based pharmacological approach is a promising therapeutic str...

(This article belongs to the Special Issue Optimization of Biomaterials for Reconstructive and Regenerative Medicine)
  • Article
  • Open Access
24 Citations
5,076 Views
13 Pages

10 July 2020

Photodynamic therapy (PDT) is a promising treatment for malignancy. However, the low molecular solubility of photosensitizers (PSs) with a low accumulation at borderline malignant potential lesions results in the tardy and ineffective management of r...

(This article belongs to the Special Issue Nanobiophotonics, Photomedicine, and Imaging)
  • Article
  • Open Access
2 Citations
3,653 Views
10 Pages

Hydration of Nucleobase as Probed by Electron Emission of Uridine-5′-Mono-Phosphate (UMP) in Aqueous Solution Induced by Nitrogen K-Shell Ionization

  • Yasuaki Takeda,
  • Hiroyuki Shimada,
  • Ryosuke Miura,
  • Masatoshi Ukai and ,
  • Kentaro Fujii,
  • Yoshihiro Fukuda and
  • Yuji Saitoh
  • + 2 authors+ 0 author

To identify the precise early radiation processes of DNA lesions, we measure electron kinetic energy spectra emitted from uridine-5′ monophosphate (UMP) in aqueous solution for the photoionization of the N 1s orbital electron and for the follow...

(This article belongs to the Special Issue Advanced Synchrotron Radiation as a Quantum Tool for Exploring Deep Life Sciences)
  • Interesting Images
  • Open Access
13 Citations
3,456 Views
4 Pages

4 May 2022

Coral reefs in the Caribbean are known to be affected by many coral diseases, yet the ecology and etiology of most diseases remain understudied. The Caribbean ciliate infection (CCI) caused by ciliates belonging to the genus Halofolliculina is a comm...

(This article belongs to the Special Issue Diversity of Coral-Associated Fauna II)
  • Article
  • Open Access
8 Citations
4,103 Views
21 Pages

Bioinspired Remineralization of Artificial Caries Lesions Using PDMAEMA/Carbomer/Calcium Phosphates Hybrid Microgels

  • Alexander Bonchev,
  • Marin Simeonov,
  • Pavletta Shestakova,
  • Radosveta Vasileva and ,
  • Rositsa Titorenkova,
  • Anton Apostolov,
  • Elena Dyulgerova and
  • Elena Vassileva
  • + 3 authors+ 0 author

21 October 2022

Dental caries remains one of the most prevalent bacterium-caused chronic diseases affecting both adults and children worldwide. The development of new materials for enhancing its remineralization is one of the most promising approaches in the field o...

(This article belongs to the Special Issue Functional Hydrogels for Biomedical Applications)
  • Article
  • Open Access
931 Views
17 Pages

4 March 2026

Post-harvest deterioration in strawberries is an urgent and critical issue that requires significant attention. Glycerol monolaurate (GML), a broad-spectrum food-grade antimicrobial agent, faces limited applicability due to its poor water solubility....

(This article belongs to the Section Food Packaging and Preservation)
  • Article
  • Open Access
27 Citations
5,074 Views
18 Pages

5 January 2024

Motivation: Clustered DNA-lesions are predominantly induced by ionizing radiation, particularly by high-LET particles, and considered as lethal damage. Quantification of this specific type of damage as a function of radiation parameters such as LET,...

  • Review
  • Open Access
70 Citations
4,845 Views
21 Pages

Oxidative Stress in Aquaculture: Pathogenic Mechanisms and Preventive Strategies in Farmed Aquatic Animals

  • Wenjing Ma,
  • Wenting Zeng,
  • Disen Zhang,
  • Yiling Zhou and ,
  • Yi Huang and
  • Yuhang Hong
  • + 1 author+ 0 author

Oxidative stress (OS), defined as a disturbance in the balance between the production and elimination of reactive oxygen species (ROS), has been widely recognized as a key factor in the pathogenesis of various aquatic animal diseases. With the intens...

(This article belongs to the Special Issue Innovations in Marine Biotechnology and Molecular Biology)
  • Case Report
  • Open Access
317 Views
9 Pages

Histopathological Diagnosis of Pulmonary Paragonimiasis: A Case Report from Ecuador

  • Katherine Fuentes-Ortiz,
  • Ligia Gabriela Velalcázar-Oñate,
  • Bruna Espín-Nuñez and
  • Manuel Calvopiña

Paragonimiasis is a foodborne trematode infection caused by Paragonimus spp. that primarily affects the lungs and may mimic tuberculosis, pulmonary mycoses, abscess, or malignancy because of its nonspecific clinical and radiological manifestations. D...

(This article belongs to the Section Neglected and Emerging Tropical Diseases)
  • Article
  • Open Access
19 Citations
4,147 Views
13 Pages

An Endoscope-like SERS Probe Based on the Focusing Effect of Silica Nanospheres for Tyrosine and Urea Detection in Sweat

  • Rongyuan Cai,
  • Lijun Yin,
  • Qian Huang,
  • Ruiyun You and ,
  • Shangyuan Feng and
  • Yudong Lu
  • + 1 author+ 0 author

27 January 2022

In this work, we developed a new type of SERS probe, which was composed of glass-SiO2-Au@MBN@Ag nanoparticles (NPs) three-dimensional Surface-enhanced Raman spectroscopy (SERS) substrate. When the laser passed through the quartz glass sheet, on the o...

(This article belongs to the Section Nanoelectronics, Nanosensors and Devices)
  • Article
  • Open Access
4 Citations
4,160 Views
10 Pages

22 May 2023

This paper describes novel and innovative amorphous calcium magnesium fluoride phosphate (ACMFP) core-shell microparticles that may be applied in preventive dentistry for the prevention of caries and the treatment of dentin hypersensitivity. The part...

(This article belongs to the Special Issue Dental Materials: Latest Advances and Prospects - Volume II)
  • Article
  • Open Access
23 Citations
4,711 Views
20 Pages

Radio-Enhancing Properties of Bimetallic Au:Pt Nanoparticles: Experimental and Theoretical Evidence

  • Daniela Salado-Leza,
  • Ali Traore,
  • Erika Porcel,
  • Diana Dragoe and ,
  • Antonio Muñoz,
  • Hynd Remita,
  • Gustavo García and
  • Sandrine Lacombe
  • + 3 authors+ 0 author

12 November 2019

The use of nanoparticles, in combination with ionizing radiation, is considered a promising method to improve the performance of radiation therapies. In this work, we engineered mono- and bimetallic core-shell gold–platinum nanoparticles (NPs)...

(This article belongs to the Special Issue Radiation-Induced Damage to DNA)
  • Article
  • Open Access
9 Citations
2,859 Views
16 Pages

Background: Nonalcoholic fatty liver disease (NAFLD) poses a risk for numerous metabolic diseases. To date, the U.S. Food and Drug Administration has not yet approved any medications for the treatment of NAFLD, for which developing therapeutic drugs...

(This article belongs to the Special Issue Delivery System for Biomacromolecule Drugs: Design and Application)
  • Article
  • Open Access
48 Citations
6,528 Views
16 Pages

Erythrocyte Membrane-Coated Arsenic Trioxide-Loaded Sodium Alginate Nanoparticles for Tumor Therapy

  • Yumei Lian,
  • Xuerui Wang,
  • Pengcheng Guo,
  • Yichen Li and ,
  • Faisal Raza,
  • Jing Su and
  • Mingfeng Qiu
  • + 2 authors+ 0 author

Arsenic trioxide (ATO) has a significant effect on the treatment of acute promyelocytic leukemia (APL) and advanced primary liver cancer, but it still faces severe side effects. Considering these problems, red blood cell membrane-camouflaged ATO-load...

(This article belongs to the Special Issue Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules)
  • Review
  • Open Access
46 Citations
12,405 Views
14 Pages

Etiology of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL): Current Directions in Research

  • Anand K. Deva,
  • Suzanne D. Turner,
  • Marshall E. Kadin,
  • Mark R. Magnusson and ,
  • H. Miles Prince,
  • Roberto N. Miranda,
  • Giorgio G. Inghirami and
  • William P. Adams
  • + 3 authors+ 0 author

21 December 2020

Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a CD30-positive, anaplastic lymphoma kinase-negative T-cell lymphoma. Where implant history is known, all confirmed cases to date have occurred in patients with exposure to textur...

  • Article
  • Open Access
628 Views
24 Pages

A Reproducible Digital Workflow for Patient-Specific 3D-Printed Teeth with Anatomically Stratified Enamel and Multi-Material Caries for Preclinical Operative Dentistry

  • Alexandru Mihai Micu,
  • Robert Mihai Bacalu,
  • Teodor Raul Constantin,
  • Alexia-Ecaterina Cârstea and ,
  • Lucian Toma Ciocan,
  • Vlad-Gabriel Vasilescu,
  • Bogdan Dimitriu,
  • Mihaela Pantea,
  • Silviu-Mirel Pițuru and
  • Marina Imre
  • + 5 authors+ 0 author

Conventional typodonts for preclinical operative dentistry are idealised and lack the variability and tactile feedback of natural teeth; virtual-reality and haptic simulators remain costly for large cohorts. This study developed a reproducible, low-c...

(This article belongs to the Special Issue Application of Biomaterials and Techniques in Dental Surgical Treatment (2nd Edition))
  • Article
  • Open Access
16 Citations
5,012 Views
15 Pages

Upconversion Nanoparticles Intercalated in Large Polymer Micelles for Tumor Imaging and Chemo/Photothermal Therapy

  • Polina A. Demina,
  • Kirill V. Khaydukov,
  • Gulalek Babayeva,
  • Pavel O. Varaksa and ,
  • Alexandra V. Atanova,
  • Maxim E. Stepanov,
  • Maria E. Nikolaeva,
  • Ivan V. Krylov,
  • Irina I. Evstratova and
  • Alla N. Generalova
  • + 10 authors+ 5 authors

Frontiers in theranostics are driving the demand for multifunctional nanoagents. Upconversion nanoparticle (UCNP)-based systems activated by near-infrared (NIR) light deeply penetrating biotissue are a powerful tool for the simultaneous diagnosis and...

(This article belongs to the Section Materials Science)
  • Article
  • Open Access
2 Citations
2,284 Views
18 Pages

Docosahexaenoic Acid-Infused Core–Shell Fibrous Membranes for Prevention of Epidural Adhesions

  • Zhuo-Hao Liu,
  • Yin-Cheng Huang,
  • Chang-Yi Kuo,
  • Darshan Tagadur Govindaraju and ,
  • Nan-Yu Chen,
  • Ping K. Yip and
  • Jyh-Ping Chen
  • + 2 authors+ 0 author

3 December 2024

Avoiding epidural adhesion following spinal surgery can reduce clinical discomfort and complications. As the severity of epidural adhesion is positively correlated with the inflammatory response, implanting a fibrous membrane after spinal surgery, wh...

(This article belongs to the Section Materials Science)
  • Article
  • Open Access
6 Citations
2,333 Views
20 Pages

D-glucuronolactone (DGL), a hepatoprotective compound widely used in clinical and energy products, was evaluated for its effects on Chinese soft-shelled turtles (Pelodiscus sinensis) through an 8-week feeding trial with dietary supplementation (0, 20...

(This article belongs to the Special Issue The Role of Oxidative Stress in Aquaculture)
  • Article
  • Open Access
580 Views
15 Pages

NO-Responsive Oleanolic Acid Self-Assembled Micelles Co-Loaded with BAY 11-7082 for Synergistic Chondroprotection and Anti-Osteoarthritis Therapy

  • Dandan Zhang,
  • Zhigang Zhang,
  • Dingxing Huang,
  • Zhuoran Sun and ,
  • Jiamin Huang,
  • Chi Zhang,
  • Qingyang Zeng,
  • Qiling Liu and
  • Wenzhuo Chen
  • + 4 authors+ 0 author

Osteoarthritis is an irreversible degenerative joint disease driven by sustained NF-κB-mediated inflammatory responses, and conventional intra-articular hyaluronic acid or small-molecule NF-κB inhibitors cannot achieve targeted on-demand...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
26 Citations
7,464 Views
22 Pages

Genetic Characteristics and Enzymatic Activities of Bacillus velezensis KS04AU as a Stable Biocontrol Agent against Phytopathogens

  • Roderic Gilles Claret Diabankana,
  • Elena Urievna Shulga,
  • Shamil Zavdatovich Validov and
  • Daniel Mawuena Afordoanyi

Bacillus velezensis has a broad application in the agricultural and industrial sectors for its biocontrol properties and its potential active secondary metabolites. The defined phenotypic characteristics of a strain vary according to its ecosystem. W...

  • Review
  • Open Access
33 Citations
29,190 Views
26 Pages

26 June 2015

This review summarises the findings of a series of studies in which the histological changes, induced in the reproductive system of Fasciola hepatica following treatment of the ovine host with the anthelmintic triclabendazole (TCBZ), were examined. A...

(This article belongs to the Special Issue Host-Parasite Interactions)