Experimental Biology: From Methods to Applications. Under the Auspices of the Italian Society of Experimental Biology, SIBS-1925

A special issue of Applied Biosciences (ISSN 2813-0464).

Deadline for manuscript submissions: closed (31 August 2024) | Viewed by 1684

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Department of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, Italy
Interests: reproduction; infertility; assisted reproductive technology; cryopreservation; environmental pollutants; oocyte; ovarian follicles; spermatozoa; embryos; histology; electron microscopy
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Special Issue Information

Dear Colleagues,

Experimental biology aims to better understand natural phenomena via experiments and tests in laboratories to prove or disprove the hypotheses.

With this Special Issue, we want to invite researchers to submit their outstanding work in all the fields of experimental biology, such as  advanced microscopy and imaging, aging, human biology and anthropology, applied biochemistry, aquatic environments, artificial intelligence applied to biomedicine, biodiversity and modeling, reproduction and infertility, biomedical and pharmaceutical biotechnology, cellular stress, environment and health, micro- and nanovesicles in biomedicine, morphology, neuroscience, nutrition and food supplements, plant biology, precision medicine, regenerative medicine, structural biology, urban biodiversity, and other related topics.

This Special Issue has the auspicies of the Italian Society of Experimental Biology, SIBS-1925, which, in 2025, is going to celebrate its first centenary of scientific activities.

Prof. Dr. Francesco Cappello
Dr. Maria Grazia Palmerini
Guest Editors

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Keywords

  • aging
  • anthropology
  • biochemistry
  • biodiversity
  • biomedicine
  • cellular stress
  • extracellular vesicles
  • marine biology
  • morphology
  • neuroscience
  • nutrition
  • precision medicine
  • regenerative medicine
  • reproduction and infertility
  • structural biology

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Published Papers (1 paper)

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Research

13 pages, 2858 KiB  
Article
Deciphering the Role of the Nucleus Accumbens Shell Area on Spatial Memory Deficits Induced by Neuropathic Pain in Rats
by Mariana Cerqueira-Nunes, Clara Monteiro, Vasco Galhardo and Helder Cardoso-Cruz
Appl. Biosci. 2024, 3(2), 283-295; https://doi.org/10.3390/applbiosci3020019 - 12 Jun 2024
Viewed by 897
Abstract
The nucleus accumbens shell (NAcSh) is a major structure associated with distinct aspects of reward and mnemonic information encoding, relying on spatial data to define optimal behavioral strategies. Chronic pain-derived striatal plasticity is considered one underpinning cause of working memory (WM) impairments. However, [...] Read more.
The nucleus accumbens shell (NAcSh) is a major structure associated with distinct aspects of reward and mnemonic information encoding, relying on spatial data to define optimal behavioral strategies. Chronic pain-derived striatal plasticity is considered one underpinning cause of working memory (WM) impairments. However, it is unclear how the NAcSh is involved in these spatial deficits. To address this, we evaluated the impact of unilateral local NAcSh electrical lesions during the execution of a food-reinforced eight-shaped spatial alternation WM task. Behavioral performance was assessed in rats after the onset of the neuropathic pain model—spared nerve injury (SNI). Our findings indicate that the induction of SNI and/or NAcSh lesions did not significantly impact the animals’ performance accuracy or motor activity during the execution of the behavioral task, but altered their response latency patterns. In addition, these manipulations did not induce significant antinociceptive effects. Collectively, these results suggest that the NAcSh may participate in specific aspects of spatial information integration and processing under neuropathic pain conditions. Full article
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