Petasin, a lipophilic sesquiterpene ester isolated from Petasites hybridus, exhibits well-documented anti-inflammatory and anti-allergic activities, although its molecular mechanisms of action remain incompletely understood. Here, we investigated its...
Polymeric membranes are widely applied in biomedical applications, including in vitro organ models. In such models, they are mostly used as supports on which cells are cultured to create functional tissue units of the desired organ. To this end, the...
This study aims to investigate the effect of operational conditions on organic fouling occurring in a direct contact membrane distillation (DCMD) system used to treat wastewater. A mixed solution of sodium alginate (SA) and bovine serum albumin (BSA)...
The proton exchange membrane fuel cell (PEMFC) is the fastest growing fuel cell technology on the market. Due to their sustainable nature, PEMFCs are widely adopted as a renewable energy resource. Fabricating a PEMFC is a costly process; hence, mathe...
In this study, polysulfone/polyvinylpyrrolidone (PSf/PVP, 20 wt%/5 wt%)-based ultrafiltration (UF) membranes reinforced with different ratios (0.5 and 1 wt%) of cellulose nanocrystals (CNCs) and cellulose nanofibres (CNFs) were prepared by the phase...
In order to alleviate membrane fouling and improve removal efficiency, a series of pretreatment technologies were applied to the ultrafiltration process. In this study, ClO2 was used as a pre-oxidation strategy for the ultrafiltration (UF) process. H...
The intestine is a complex organ whose main functions are food digestion and nutrient absorption. It is therefore of great interest for pharmaceutical research as a preferred route for drug delivery. In vitro intestinal models are valuable tools for...
Routine manipulation of the mouse genome has become a landmark in biomedical research. Traits that are only associated with advanced developmental stages can now be investigated within a living organism, and the in vivo analysis of corresponding phen...
A series of novel vanillin-derived halolactones bearing a phenolic ring at the β-position were comprehensively evaluated for their antioxidant and anti-inflammatory properties. The most active derivative, trans-4-(4′-hydroxy-3′-metho...
Membrane-based processes are taking a more and more prominent position in the search for sustainable and energy-efficient gas separation applications. It is known that the separation performance of pure polymers may significantly be improved by the d...
Colorectal cancer (CRC) is the third most common cancer worldwide, imposing a significant burden on public health. Despite the use of various therapeutic strategies, the prognosis for patients with metastatic and drug-resistant CRC remains poor, whic...
Research on how a stratified oral epithelium gained the capability to create the hardest hydroxyapatite-based mineralized tissue produced biologically to protect the surfaces of teeth has been ongoing for at least 175 years. Many advances have been m...
The increasing prevalence of multidrug-resistant bacteria necessitates alternative therapeutic strategies that combine antimicrobial efficacy with immunomodulatory properties. Here, we report the immunostimulatory activity and antibacterial potential...
Recently, the need for energy-saving and eco-friendly energy systems is increasing as problems such as rapid climate change and air pollution are getting more serious. While research on a power generation system using hydrogen energy-based fuel cells...
The Fluid–Mosaic Model has been the accepted general or basic model for biomembrane structure and organization for the last 50 years. In order to establish a basic model for biomembranes, some general principles had to be established, such as t...
In this work, we combined the non-solvent induced phase separation (NIPS) and further cross-linking by cations towards the preparation of nanofiltration membranes based on sodium alginate, a biodegradable, natural polymer. Acetone, ethanol, toluene,...
The pervaporation separation of organic compounds from acetone-butanol-ethanol (ABE) fermentation model solutions was studied using activated carbon (AC) nanoparticle-poly (dimethylsiloxane) (PDMS) mixed matrix membranes (MMM). The effects of the ope...
Uveal melanoma (UM) is the most common intraocular tumor in adults, and nearly 50% of patients develop metastatic disease with a high mortality rate. Therefore, the development of relevant preclinical in vivo models that accurately recapitulate the m...
The plasma membrane (PM) has undergone important conceptual changes during the history of scientific research, although it is undoubtedly a cellular organelle that constitutes the first defining characteristic of cellular life. Throughout history, th...
The goal of this study was to elucidate the interaction of complex feed solutions under modified membrane fouling models for constant flux operation. The polyvinylidene fluoride membrane (PVDF) was tested for three types of solutions containing inorg...
In recent years, electrochemical methods utilizing reactive electrochemical membranes (REM) have been considered as a promising technology for efficient degradation and mineralization of organic compounds in natural, industrial and municipal wastewat...
The use of reactive electrochemical membranes (REM) in flow-through mode during the anodic oxidation of organic compounds makes it possible to overcome the limitations of plate anodes: in the case of REM, the area of the electrochemically active surf...
A daily consumption of cranberry juice (CJ) is linked to many beneficial health effects due to its richness in polyphenols but could also awake some intestinal discomforts due to its organic acid content and possibly lead to intestinal inflammation....
Supramolecular self-assembly of membrane constituents within a phospholipid bilayer creates complex functional platforms in biological cells that operate in intracellular signaling, trafficking and membrane remodeling. Synthetic polyphilic compounds...
A performance simulator of spiral wound membrane (SWM) modules used for desalination is a valuable tool for process design and optimization. The existing state-of-the-art mesoscale simulation tools account for the spatial non-uniformities created by...
The widespread use of surfactants increasingly requires the development and application of reliable methods for the demineralization of wastewaters, preventing environmental pollution. One of the most reliable and effective methods of demineralizatio...
The plasma membrane of mammalian cells is involved in a wide variety of cellular processes, including, but not limited to, endocytosis and exocytosis, adhesion and migration, and signaling. The regulation of these processes requires the plasma membra...
Photocatalytic ceramic membranes have attracted considerable attention for industrial wastewater treatment. However, morphological control of the membrane surface to improve its photocatalytic reactivity for the degradation of organic pollutants rema...
Membrane fouling is a non-negligible issue affecting the performance of membrane systems. Particularly, organic fouling is the most persistent and severe form of fouling. The complexation between inorganic and organic matter may exacerbate membrane o...
Cell membranes are crucial elements in living organisms, serving as protective barriers and providing structural support for cells. They regulate numerous exchange and communication processes between cells and their environment, including interaction...
Lateral phase separation within lipid bilayer membranes has attracted considerable attention in the fields of biophysics and cell biology. Living cells organize laterally segregated compartments, such as raft domains in an ordered phase, and regulate...
Studies on the budding yeast Saccharomyces cerevisiae have revealed that fungal plasma membranes are organized into different subdomains. One new domain termed MCC/eisosomes consists of stable punctate patches that are distinct from lipid rafts. The...
Background/Objectives: BRI is a synthetic arylamide polymer designed to mimic the electrostatic and amphiphilic features of defensin-type antimicrobial peptides (AMPs), although its molecular organization and activity have not been experimentally val...
Membrane fouling caused by complex greywater synthesized by personal care products and detergents commercially available for household applications was investigated using dead-end microfiltration (MF) and analyzed systematically by a multistage Hermi...
Recently, dynamic membrane bioreactor (DMBR) has gradually gained the interest of researchers for the development of membrane technology. In this paper, we set up parallel experiments to investigate the effect of powder activated carbon (PAC) on orga...
The lipid composition of eye lens fiber cell membranes varies among species, and these differences increase as a function of lifespan. However, the way in which the lipids of the fiber cell membranes are organized in different animals has not yet bee...
In this numerical study, the performance of ceramic-based mullite hollow fiber (HF) membranes in a direct contact membrane distillation (DCMD) process was evaluated. Three types of membranes were tested: (i) hydrophobic membrane C8-HFM, (ii) rod-like...
Organic fouling in the forward osmosis process is complex and influenced by different parameters in the forward osmosis such as type of feed and draw solution, operating conditions, and type of membrane. In this article, we reviewed organic fouling i...
Membranes play a key role in many organ-on-a-chip (OOC) platforms due to nutrient and mass transport, barrier formation, and mechanical signaling. However, despite their key role in OOC devices, the relationship between membrane design parameters and...
Membrane fouling is a major hindrance to widespread wastewater treatment applications. This study optimizes operating parameters in membrane rotating biological contactors (MRBC) for maximized membrane fouling through Response Surface Methodology (RS...
This work has been focused on the one-step fabrication by electrospinning of polyamide 6 (PA6) nanofibre membranes modified with titanium dioxide nanoparticles (TiO2), where these TiO2 nanoparticles aggregates could induce a photocatalytic activity....
A porcine model with a stabilized segmental femoral defect was used, in which commercial or experimental bone cements were implanted following the principles of the Masquelet technique. After 45 days, considered long enough for induced membrane matur...
Cellular organization relies on both membrane-bound organelles and membraneless biomolecular condensates formed through liquid–liquid phase separation. Recent discoveries reveal intricate coupling between lipid membrane organization and condens...
Cake-enhanced concentration polarization (CECP) has been ascribed as the main cause of flux decline in dead-end filtration. An unfamiliar approach was used to investigate the role of CECP effects in the fouling of a nanofiltration membrane (NF-270) t...
Ultrafiltration membranes are widely used in wastewater reuse systems, but membrane fouling caused by effluent organic matter (EfOM) remains a major limitation. In this study, electrocatalytic oxidation (EO) was applied as a pretreatment strategy to...
Organic micropollutants (OMPs) present in water and wastewater are in the spotlight because of their potentially harmful effects even at low concentrations and the difficulties of their elimination in urban wastewater treatment plants (UWWTPs). This...
This work presents the photocatalytic degradation of organic pollutants in water with TiO2 and TiO2/Ag membranes prepared by immobilising photocatalysts on ceramic porous tubular supports. The permeation capacity of TiO2 and TiO2/Ag membranes was che...
We conduct molecular dynamics simulations of model heterogeneous membranes and their interactions with a 24-amino acid peptide—NAF-144–67. NAF-144–67 is an anticancer peptide that selectively permeates and kills malignant cells; it...
Archaeal membranes exhibit remarkable stability under extreme environmental conditions, a feature attributed to their unique lipid composition. While it is widely accepted that tetraether lipids confer structural integrity by forming monolayers, the...
Breast cancer remains one of the leading causes of cancer-related mortality among women worldwide, highlighting the urgent need for novel therapeutic agents with improved efficacy and selectivity. In this study, we investigated the anticancer potenti...
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