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785 Results Found

  • Article
  • Open Access
1 Citations
869 Views
25 Pages

Robust Maximum Half-Normal Multivariate Control Chart Based on Det-MCD and Fast-MCD Estimators

  • Muhammad Ahsan,
  • Awang Putra Sembada R,
  • Muhammad Mashuri,
  • Wibawati and ,
  • Dinda Ayu Safira and
  • Muhammad Hisyam Lee
  • + 1 author+ 0 author

4 April 2026

Every company conducts evaluations to ensure the quality of its products and services, often utilizing multivariate simultaneous control charts to monitor the process mean and variability concurrently. The objective of this study is to overcome a sig...

  • Article
  • Open Access
12 Citations
3,230 Views
10 Pages

MCD Inhibits Lipid Deposition in Goat Intramuscular Preadipocytes

  • Changheng Yang,
  • Qi Li,
  • Yaqiu Lin,
  • Yong Wang and ,
  • Hengbo Shi,
  • Lian Huang,
  • Wangsheng Zhao,
  • Hua Xiang and
  • Jiangjiang Zhu
  • + 4 authors+ 0 author

8 February 2023

Malonyl-CoA decarboxylase (MCD) is a major regulator of fatty acid oxidation catalyzing the decarboxylation of malonyl coenzyme A (malonyl-CoA). Although its involvement in human diseases has been well studied, its role in intramuscular fat (IMF) dep...

(This article belongs to the Section Animal Genetics and Genomics)
  • Article
  • Open Access
59 Citations
10,370 Views
14 Pages

Intestinal Microbiota Protects against MCD Diet-Induced Steatohepatitis

  • Kai Markus Schneider,
  • Antje Mohs,
  • Konrad Kilic,
  • Lena Susanna Candels and ,
  • Carsten Elfers,
  • Eveline Bennek,
  • Lukas Ben Schneider,
  • Felix Heymann,
  • Nikolaus Gassler and
  • Christian Trautwein
  • + 6 authors+ 1 author

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in western countries, with a continuously rising incidence. Gut-liver communication and microbiota composition have been identified as critical drivers of the NAFLD progressio...

(This article belongs to the Special Issue Liver Cirrhosis and Hepatocellular Carcinoma: Pathogenesis, Diagnosis and Treatment)
  • Feature Paper
  • Article
  • Open Access
8 Citations
4,004 Views
12 Pages

MCD and Induced CD of a Tetraphenoxyperylene-Based Dye in Chiral Solvents: An Experimental and Computational Study

  • Simone Ghidinelli,
  • Marco Fusè,
  • Giuseppe Mazzeo,
  • Sergio Abbate and
  • Giovanna Longhi

28 May 2022

The magnetic circular dichroism (MCD) spectrum of N,N′-bis(2,6-diisopropylphenyl)-1,6,7,12-tetraphenoxyperylene-3,4:9,10-tetracarboxydiimide, also known as Lumogen Red 300 or ROT-300, has been recorded both in achiral and chiral solvents. The i...

(This article belongs to the Special Issue Asymmetric Molecules and Chirality Recognition)
  • Article
  • Open Access
6 Citations
3,698 Views
17 Pages

MCD Diet Modulates HuR and Oxidative Stress-Related HuR Targets in Rats

  • Andrea Ferrigno,
  • Lucrezia Irene Maria Campagnoli,
  • Annalisa Barbieri,
  • Nicoletta Marchesi and ,
  • Alessia Pascale,
  • Anna Cleta Croce,
  • Mariapia Vairetti and
  • Laura Giuseppina Di Pasqua
  • + 3 authors+ 0 author

The endogenous antioxidant defense plays a big part in the pathogenesis of non-alcoholic fatty liver disease (NAFLD), a common metabolic disorder that can lead to serious complications such as cirrhosis and cancer. HuR, an RNA-binding protein of the...

(This article belongs to the Special Issue Innovative Molecular Target and Therapeutic Approaches in Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis (NAFLD/NASH) 3.0)
  • Article
  • Open Access
3 Citations
2,007 Views
25 Pages

Portulaca oleracea Extract Modulates Diet-Dependent Neuroplasticity in a Murine Model of MCD-Induced NAFLD and Depression

  • Smaranda Ioana Mitran,
  • Mădălina Iuliana Muşat,
  • Cornelia Bejenaru,
  • George Dan Mogoşanu and ,
  • Ianis Kevyn Ştefan Boboc,
  • Robertina-Iulia Tudoraşcu,
  • Georgică Târtea,
  • Ovidiu Mircea Zlătian,
  • Antonia Blendea and
  • Ludovic Everard Bejenaru
  • + 7 authors+ 2 authors

15 October 2025

Non-alcoholic fatty liver disease (NAFLD) is increasingly recognized as a systemic condition with neuropsychiatric comorbidities, including depression. Growing evidence for the neuroprotective, antidepressant, and anxiolytic potential of Portulaca ol...

(This article belongs to the Section Bioactives and Nutraceuticals)
  • Article
  • Open Access
4 Citations
1,709 Views
22 Pages

4 January 2026

The concordance correlation coefficient (CCC) is a popular measure of agreement between two continuous variables but is highly sensitive to outliers and data contamination. In this study, we propose a robust reformulation of the CCC by replacing clas...

(This article belongs to the Special Issue Advances in Statistical Approaches with Applications for Multivariate Data Analysis)
  • Article
  • Open Access
41 Citations
10,951 Views
26 Pages

Burned Area Mapping in the North American Boreal Forest Using Terra-MODIS LTDR (2001–2011): A Comparison with the MCD45A1, MCD64A1 and BA GEOLAND-2 Products

  • José Andrés Moreno Ruiz,
  • José Rafael García Lázaro,
  • Isabel Del Águila Cano and
  • Pedro Hernández Leal

13 January 2014

An algorithm based on a Bayesian network classifier was adapted to produce 10-day burned area (BA) maps from the Long Term Data Record Version 3 (LTDR) at a spatial resolution of 0.05° (~5 km) for the North American boreal region from 2001 to 2011. T...

  • Article
  • Open Access
3 Citations
4,648 Views
20 Pages

The application of aluminum matrix composites (AMCs) allows the reduction of moving loads for increased efficiency in modern technical systems. However, the presence of reinforcing particles leads to challenges in machining of AMCs, typically requiri...

(This article belongs to the Special Issue Surface Integrity in Machining)
  • Review
  • Open Access
11 Citations
3,997 Views
17 Pages

Increase in Vascular Endothelial Growth Factor (VEGF) Expression and the Pathogenesis of iMCD-TAFRO

  • Gordan Srkalovic,
  • Sally Nijim,
  • Maya Blanka Srkalovic and
  • David Fajgenbaum

TAFRO (thrombocytopenia (T), anasarca (A), fever (F), reticulin fibrosis (F/R), renal failure (R), and organomegaly (O)) is a heterogeneous clinical subtype of idiopathic multicentric Castleman disease (iMCD) associated with a significantly poorer pr...

(This article belongs to the Special Issue Diagnosis, Pathogenesis and Treatment of TAFRO Syndrome)
  • Article
  • Open Access
24 Citations
9,240 Views
16 Pages

Assessment of MODIS BRDF/Albedo Model Parameters (MCD43A1 Collection 6) for Directional Reflectance Retrieval

  • Xianghong Che,
  • Min Feng,
  • Joseph O. Sexton,
  • Saurabh Channan and ,
  • Yaping Yang and
  • Qing Sun
  • + 1 author+ 0 author

4 November 2017

Measurements of solar radiation reflected from Earth’s surface are the basis for calculating albedo, vegetation indices, and other terrestrial attributes. However, the “bi-directional” geometry of illumination and viewing (i.e., the Bi-directional Re...

  • Article
  • Open Access
1 Citations
1,396 Views
22 Pages

5 January 2026

With the growing deployment of Flying Ad hoc Networks (FANETs) in military and civilian applications, constructing a stable and efficient communication backbone has become a critical challenge. This paper tackles the Cluster Head (CH) optimization pr...

(This article belongs to the Section Sensor Networks)
  • Article
  • Open Access
1,095 Views
11 Pages

cellMCD Effectively Discovers Drug Resistance and Sensitivity Genes for Acute Myeloid Leukemia

  • Dora Obodo,
  • Nam H. K. Nguyen,
  • Xueyuan Cao,
  • Phani Krishna Parcha and ,
  • Christopher D. Vulpe,
  • Jatinder K. Lamba and
  • Stanley B. Pounds
  • + 2 authors+ 0 author

1 January 2026

Background: Rapid advances in biotechnology provide researchers with the opportunity to integrate omics profiles (genomics, epigenomics, transcriptomics, proteomics, etc.) with multiple phenotypes or experimental conditions. In cancers such as acute...

(This article belongs to the Section Human Genomics and Genetic Diseases)
  • Article
  • Open Access
10 Citations
6,508 Views
12 Pages

The VIS/NIR Land and Snow BRDF Atlas for RTTOV: Comparison between MODIS MCD43C1 C5 and C6

  • Jérôme Vidot,
  • Pascal Brunel,
  • Marie Dumont,
  • Carlo Carmagnola and
  • James Hocking

23 December 2017

A monthly mean land and snow Bidirectional Reflectance Distribution Function (BRDF) atlas for visible and near infrared parts of the spectrum has been developed for Radiative Transfer for Television Infrared Observation Satellite (TIROS) Operational...

(This article belongs to the Special Issue Advancing Earth Surface Representation via Enhanced Use of Earth Observations in Monitoring and Forecasting Applications)
  • Review
  • Open Access
38 Views
21 Pages

6 November 2026

Debneyol biosynthesis in Nicotiana is regulated by the microRNA 1919 (miR1919)–miR1919-targeted cell death factor 1 (MCD1) module, but the mechanisms linking enzyme association to defence-metabolite output remain incompletely resolved. Although...

(This article belongs to the Special Issue Plant Interactions with Bacteria and Fungi: Mechanisms, Ecology, and Applications)
  • Article
  • Open Access
10 Citations
5,021 Views
18 Pages

Land Cover Based Landscape Pattern Dynamics of Anhui Province Using GlobCover and MCD12Q1 Global Land Cover Products

  • Jinling Zhao,
  • Jie Wang,
  • Yu Jin,
  • Lingling Fan and ,
  • Chao Xu,
  • Dong Liang and
  • Linsheng Huang
  • + 2 authors+ 0 author

22 April 2018

The development and free distribution of global land cover (GLC) products have greatly assisted in the evolution and analysis of relationships between land cover and landscape pattern. In this study, GlobCover and MCD12Q1 GLC datasets of 2005 and 200...

  • Article
  • Open Access
23 Citations
5,048 Views
18 Pages

MCD Diet Rat Model Induces Alterations in Zinc and Iron during NAFLD Progression from Steatosis to Steatohepatitis

  • Giuseppina Palladini,
  • Laura Giuseppina Di Pasqua,
  • Marta Cagna,
  • Anna Cleta Croce and ,
  • Stefano Perlini,
  • Barbara Mannucci,
  • Antonella Profumo,
  • Andrea Ferrigno and
  • Mariapia Vairetti
  • + 4 authors+ 0 author

We evaluate the effects of the methionine-choline-deficient (MCD) diet on serum and hepatic zinc (Zn) and iron (Fe) and their relationships with matrix metalloproteinases (MMPs) and their modulators (TIMPs and RECK) as well as hepatic fatty acids usi...

(This article belongs to the Special Issue Innovative Molecular Target and Therapeutic Approaches in Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis (NAFLD/NASH) 2.0)
  • Review
  • Open Access
1 Citations
1,136 Views
11 Pages

KSHV and Human Diseases: Beyond KS, PEL and MCD

  • Caroline Grace Firmin,
  • Lu Dai and
  • Zhiqiang Qin

Kaposi’s Sarcoma-associated herpesvirus (KSHV) has been etiologically linked to several human cancers, including Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). However, recent stu...

(This article belongs to the Section Virology)
  • Article
  • Open Access
120 Citations
14,008 Views
23 Pages

16 November 2015

Land cover plays an important role in the climate and biogeochemistry of the Earth system. It is of great significance to produce and evaluate the global land cover (GLC) data when applying the data to the practice at a specific spatial scale. The ob...

(This article belongs to the Special Issue Advances in Spatio-Temporal Data Analysis and Mining)
  • Article
  • Open Access
6 Citations
3,527 Views
16 Pages

Study on Accuracy Evaluation of MCD19A2 and Spatiotemporal Distribution of AOD in Arid Zones of Central Asia

  • Zhengnan Zhu,
  • Zhe Zhang,
  • Fangqing Liu,
  • Zewei Chen and ,
  • Yuxin Ren and
  • Qingfu Guo
  • + 1 author+ 0 author

20 September 2023

The Central Asian arid zone is the largest non-territorial arid zone in the world, so it is particularly important to understand the optical properties of aerosols in this region. In this paper, we validate the MCD19A2 atmospheric aerosol optical dep...

(This article belongs to the Special Issue Theory, Model, Technology, and Application of Remote Sensing in Sustainability)
  • Article
  • Open Access
1 Citations
1,443 Views
16 Pages

Benchmarking Control Strategies for Multi-Component Degradation (MCD) Detection in Digital Twin (DT) Applications

  • Atuahene Kwasi Barimah,
  • Akhtar Jahanzeb,
  • Octavian Niculita,
  • Andrew Cowell and
  • Don McGlinchey

29 August 2025

Digital Twins (DTs) have become central to intelligent asset management within Industry 4.0, enabling real-time monitoring, diagnostics, and predictive maintenance. However, implementing Prognostics and Health Management (PHM) strategies within DT fr...

(This article belongs to the Section Internet of Things (IoT) and Industrial IoT)
  • Article
  • Open Access
12 Citations
3,831 Views
16 Pages

Tribological Performance of Microcrystalline Diamond (MCD) and Nanocrystalline Diamond (NCD) Coating in Dry and Seawater Environment

  • Hui Zhang,
  • Hui Song,
  • Ming Pang,
  • Guoyong Yang and ,
  • Fengqin Ji,
  • Nan Jiang and
  • Kazuhito Nishimura
  • + 2 authors+ 0 author

23 September 2022

In the present study, the tribological properties of diverse crystalline diamond coating with micro (MCD) and nanometer (NCD) sizes, fabricated by the microwave plasma chemical vapor deposition (MPCVD) method, are systematically investigated in dry a...

(This article belongs to the Special Issue Additive Manufacturing (AM) for Advanced Materials and Structures: Green and Intelligent Development Trend)
  • Review
  • Open Access
10 Citations
3,857 Views
10 Pages

Idiopathic multicentric Castleman disease (iMCD) and TAFRO syndrome present a variety of symptoms thought to be caused by excessive inflammatory cytokines and chemokines, but the underlying mechanisms are unknown. iMCD is broadly classified into two...

(This article belongs to the Section Gene and Cell Therapy)
  • Viewpoint
  • Open Access
4 Citations
3,671 Views
7 Pages

TAFRO (thrombocytopenia, anasarca, fever, reticulin fibrosis of bone marrow/renal dysfunction, organomegaly) syndrome is a systemic inflammatory disorder of unknown etiology. It has been recognized as a subtype of idiopathic multicentric Castleman di...

(This article belongs to the Special Issue Diagnosis, Pathogenesis and Treatment of TAFRO Syndrome)
  • Article
  • Open Access
22 Citations
3,856 Views
10 Pages

13 September 2018

The drilling of carbon fiber reinforced plastics (CFRP) is a significant topic for the aircraft industry. However, CFRP are materials which are difficult to cut due to their unique properties. This paper studies tools with excellent cutting performan...

(This article belongs to the Section Mechanical Engineering)
  • Communication
  • Open Access
9 Citations
3,933 Views
14 Pages

T-Cells Subsets in Castleman Disease: Analysis of 28 Cases Including Unicentric, Multicentric and HHV8-Related Clinical Forms

  • Sara Fraticelli,
  • Marco Lucioni,
  • Giuseppe Neri,
  • Deborah Marchiori and ,
  • Caterina Cristinelli,
  • Michele Merli,
  • Rodolfo Monaco,
  • Tiziana Borra,
  • Antonio Lazzaro and
  • Marco Paulli
  • + 7 authors+ 2 authors

Castleman disease (CD) is a rare lymphoproliferative disorder that includes various clinico-pathological subtypes. According to clinical course, CD is divided into unicentric CD (UCD) and multicentric CD (MCD). MCD is further distinguished based on t...

(This article belongs to the Special Issue Immunophenotyping in Autoimmune Diseases and Cancer, 3rd Edition)
  • Article
  • Open Access
6 Citations
3,500 Views
19 Pages

The high-purity G5 graphite material is widely used for glass moulding and provides high hardness and brittleness because it is sintered to fine particles unlike other graphite materials. Hence, tool cutting of a G5 workpiece is performed by local fr...

(This article belongs to the Special Issue Ultra-Precision Manufacturing Technology)
  • Article
  • Open Access
21 Citations
4,748 Views
23 Pages

About Validation-Comparison of Burned Area Products

  • Germán M. Valencia,
  • Jesús A. Anaya,
  • Éver A. Velásquez,
  • Rubén Ramo and
  • Francisco J. Caro-Lopera

4 December 2020

This paper proposes a validation-comparison method for burned area (BA) products. The technique considers: (1) bootstrapping of scenes for validation-comparison and (2) permutation tests for validation. The research focuses on the tropical regions of...

  • Article
  • Open Access
3 Citations
2,040 Views
15 Pages

Target Detection Method for Soil-Dwelling Termite Damage Based on MCD-YOLOv8

  • Peidong Jiang,
  • Lai Jiang,
  • Fengyan Wu,
  • Tengteng Che and ,
  • Ming Wang and
  • Chuandong Zheng
  • + 1 author+ 0 author

31 March 2025

With global climate change and the deterioration of the ecological environment, the safety of hydraulic engineering faces severe challenges, among which soil-dwelling termite damage has become an issue that cannot be ignored. Reservoirs and embankmen...

(This article belongs to the Section Industrial Sensors)
  • Article
  • Open Access
18 Citations
4,702 Views
23 Pages

22 September 2020

This paper presents an accuracy assessment of the main global scale Burned Area (BA) products, derived from daily images of the Moderate-Resolution Imaging Spectroradiometer (MODIS) Fire_CCI 5.1 and MCD64A1 C6, as well as the previous versions of bot...

(This article belongs to the Special Issue Remote Sensing and Geoinformatics in Wildfire Management)
  • Article
  • Open Access
16 Citations
3,799 Views
15 Pages

20 October 2023

As the principal factor affecting global food production, accurate identification of agricultural pests and diseases is crucial in ensuring a sustainable food supply. However, existing methods lack sufficient performance in terms of accuracy and real...

  • Article
  • Open Access
1,234 Views
27 Pages

Accurate classification of cognitive levels in instructional dialogues is essential for personalized education and intelligent teaching systems. However, most existing methods predominantly rely on static textual features and a shallow semantic analy...

  • Article
  • Open Access
12 Citations
6,243 Views
18 Pages

iPla2β Deficiency Suppresses Hepatic ER UPR, Fxr, and Phospholipids in Mice Fed with MCD Diet, Resulting in Exacerbated Hepatic Bile Acids and Biliary Cell Proliferation

  • Yanan Ming,
  • Xingya Zhu,
  • Sabine Tuma-Kellner,
  • Alexandra Ganzha and ,
  • Gerhard Liebisch,
  • Hongying Gan-Schreier and
  • Walee Chamulitrat
  • + 2 authors+ 0 author

12 August 2019

Background: Group VIA calcium-independent phospholipase A2 (iPla2β) regulates homeostasis and remodeling of phospholipids (PL). We previously showed that iPla2β−/− mice fed with a methionine-choline-deficient diet (MCD) exhibite...

(This article belongs to the Special Issue Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis)
  • Article
  • Open Access
3 Citations
2,254 Views
19 Pages

Myeloid-Specific STAT3 Deletion Aggravates Liver Fibrosis in Mice Fed a Methionine- and Choline-Deficient Diet via Upregulation of Hepatocyte-Derived Lipocalin-2

  • Kyung Eun Kim,
  • Hyun Joo Shin,
  • Hyeong Seok An,
  • Eun Ae Jeong and ,
  • Yundong Sun,
  • Jiwon Oh,
  • Jiwoo Park,
  • Jaewoong Lee,
  • Seung-Soon Im and
  • Gu Seob Roh
  • + 5 authors+ 0 author

29 September 2025

The signal transducer and activator of transcription 3 (STAT3) in myeloid cells suppresses proinflammatory cytokine production and reduces collagen deposition. However, its role in methionine- and choline-deficient (MCD) diet-fed mice remains unclear...

  • Article
  • Open Access
2 Citations
1,433 Views
19 Pages

MCD-Net: Robust Multi-UAV Cooperative Detection via Secondary Matching and Hybrid Fusion for Occluded Objects

  • Huijie Zhou,
  • Zijun Yang,
  • Aitong Ma,
  • Wei Zhang and ,
  • Hong Zhang and
  • Yifeng Niu
  • + 1 author+ 0 author

24 October 2025

Multi-Unmanned Aerial Vehicle (UAV) cooperative detection systems enhance perception by sharing object information from well-perceived UAVs to perception-limited UAVs via cross-view projection. However, such projections often suffer from misalignment...

(This article belongs to the Section Artificial Intelligence in Drones (AID))
  • Case Report
  • Open Access
2 Citations
2,576 Views
10 Pages

Tacrolimus Treatment for TAFRO Syndrome

  • Taiichiro Shirai,
  • Shinya Ichikawa and
  • Jun Saegusa

TAFRO syndrome is an acute systemic inflammatory disorder characterized by thrombocytopenia, anasarca, fever, reticulin myelofibrosis, renal dysfunction, and organomegaly. While its lymph node pathology is similar to that of idiopathic multicentric C...

(This article belongs to the Special Issue Diagnosis, Pathogenesis and Treatment of TAFRO Syndrome)
  • Case Report
  • Open Access
5 Citations
4,085 Views
6 Pages

Background: POEMS syndrome (POEMS) is a rare plasma cell clonal paraneoplastic syndrome consisting of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes presenting with idiopathic multicentric Castleman disease (iMCD)...

(This article belongs to the Topic Diagnostic Imaging and Pathology in Cancer Research)
  • Article
  • Open Access
14 Citations
4,004 Views
16 Pages

Atractylodes lancea Rhizome Polysaccharide Alleviates MCD Diet-Induced NASH by Inhibiting the p53/mTOR Pathway

  • Dajin Pi,
  • Zheng Liang,
  • Maoxing Pan,
  • Jianwei Zhen and ,
  • Chuiyang Zheng,
  • Jinyue Pan,
  • Wen Fan,
  • Qingliang Song,
  • Qinhe Yang and
  • Yupei Zhang
  • + 5 authors+ 0 author

16 October 2024

Nonalcoholic steatohepatitis (NASH) is a form of chronic liver disease that is characterized by liver inflammation and steatosis, with possible progression to fibrosis. Currently, no drugs have been approved for the treatment of NASH. In this study,...

(This article belongs to the Special Issue Nonalcoholic Fatty Liver Disease/Metabolic Associated Fatty Liver Disease: New Insights 3.0)
  • Article
  • Open Access
413 Views
16 Pages

Schisandrin B Targets the PPARγ-MAPK Signaling Axis to Ameliorate High-Fat MCD Diet-Induced MASLD in Mice

  • Xi-Yuan Feng,
  • Meng Gao,
  • Fei-Long Liu,
  • Ming-Ze Li and ,
  • Xiao-Li Cui,
  • Meng-Yang Wang,
  • Zhi-Hong Zhang,
  • He Li,
  • Chun-Mei Wang and
  • Jing-Hui Sun
  • + 5 authors+ 0 author

28 August 2026

Objectives: This study focuses on exploring the mechanism by which Schisandrin B (Sch B) regulates metabolic dysfunction-associated steatotic liver disease (MASLD) mice induced by a high-fat methionine–choline-deficient (MCD) diet through the a...

(This article belongs to the Section Pharmacology)
  • Article
  • Open Access
21 Citations
4,713 Views
21 Pages

Potential Urine Proteomic Biomarkers for Focal Segmental Glomerulosclerosis and Minimal Change Disease

  • Natalia V. Chebotareva,
  • Anatoliy Vinogradov,
  • Alexander G. Brzhozovskiy,
  • Daria N. Kashirina and ,
  • Maria I. Indeykina,
  • Anna E. Bugrova,
  • Marina Lebedeva,
  • Sergey Moiseev,
  • Evgeny N. Nikolaev and
  • Alexey S. Kononikhin
  • + 5 authors+ 0 author

20 October 2022

Primary focal segmental glomerulosclerosis (FSGS), along with minimal change disease (MCD), are diseases with primary podocyte damage that are clinically manifested by the nephrotic syndrome. The pathogenesis of these podocytopathies is still unknown...

(This article belongs to the Special Issue Chronic Kidney Disease: Underlying Molecular Mechanisms)
  • Case Report
  • Open Access
2 Citations
3,206 Views
6 Pages

4 January 2022

Idiopathic multicentric Castleman disease (iMCD) is characterized by the benign proliferation of lymphoid cells in multiple regions. However, the co-occurrence of epithelial malignancy and idiopathic multicentric Castleman disease (iMCD) is rarely re...

  • Feature Paper
  • Article
  • Open Access
6 Citations
4,499 Views
26 Pages

17 June 2022

This paper introduces a closed-form expression for the Kullback–Leibler divergence (KLD) between two central multivariate Cauchy distributions (MCDs) which have been recently used in different signal and image processing applications where non-...

(This article belongs to the Special Issue Information and Divergence Measures)
  • Case Report
  • Open Access
6 Citations
2,967 Views
8 Pages

19 September 2022

Idiopathic multicentric Castleman disease (iMCD) can be challenging to distinguish clinically and histopathologically from Immunoglobulin G4-related disease (IgG4RD). A 73-year-old man was referred to a rheumatologist for suspected autoimmune-related...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Case Report
  • Open Access
1,559 Views
9 Pages

The Utility of IgG4/IgG Ratio in the Diagnosis of Multicentric Castleman Disease: A Case Report of HHV8+ Castleman Disease in a Patient with Classical Hodgkin’s Lymphoma

  • Adam Hagele,
  • Philip Kay,
  • Kevin Nishino,
  • Akhil Mehta and ,
  • Yan Liu,
  • Anthony L. Nguyen and
  • Eric Lau
  • + 2 authors+ 0 author

Background/Objectives: Multicentric Castleman Disease (MCD) is a rare lymphoproliferative disorder that can mimic IgG4-related disease (IgG4-RD), particularly in patients presenting with elevated serum IgG4. Accurate diagnosis is crucial given differ...

  • Article
  • Open Access
15 Citations
7,347 Views
15 Pages

Carbohydrate-restricted diets have become very popular due to their numerous health benefits. The aim of this study was to determine the influence of 4 weeks of a well-planned, low-energy moderate-carbohydrate diet (MCD) and a low-energy mixed diet (...

(This article belongs to the Section Global Health)
  • Article
  • Open Access
48 Citations
6,152 Views
12 Pages

MicroRNA-29a Disrupts DNMT3b to Ameliorate Diet-Induced Non-Alcoholic Steatohepatitis in Mice

  • Ya-Ling Yang,
  • Hsing-Chun Kuo,
  • Feng-Sheng Wang and
  • Ying-Hsien Huang

MicroRNA-29 (miR-29) has been found to reduce liver inflammation and fibrosis following a liver injury. Meanwhile, DNA methyltransferase has been reported to participate in the development of non-alcoholic steatohepatitis (NASH). The aim of this stud...

(This article belongs to the Section Biochemistry)
  • Article
  • Open Access
36 Citations
9,479 Views
22 Pages

4 February 2015

Non-alcoholic fatty liver disease, including non-alcoholic steatohepatitis (NASH), appears to be increasingly common worldwide. The aim of the study was to investigate the effects of 6-gingerol ((S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone)...

  • Article
  • Open Access
2 Citations
2,443 Views
10 Pages

Novel 4H-SiC Double-Trench MOSFETs with Integrated Schottky Barrier and MOS-Channel Diodes for Enhanced Breakdown Voltage and Switching Characteristics

  • Peiran Wang,
  • Chenglong Li,
  • Chenkai Deng,
  • Qinhan Yang and ,
  • Shoucheng Xu,
  • Xinyi Tang,
  • Ziyang Wang,
  • Wenchuan Tao,
  • Nick Tao and
  • Hongyu Yu
  • + 6 authors+ 1 author

18 June 2025

In this study, a novel silicon carbide (SiC) double-trench MOSFET (DT-MOS) combined Schottky barrier diode (SBD) and MOS-channel diode (MCD) is proposed and investigated using TCAD simulations. The integrated MCD helps inactivate the parasitic body d...

(This article belongs to the Section Nanoelectronics, Nanosensors and Devices)
  • Case Report
  • Open Access
4 Citations
3,472 Views
10 Pages

A Case of Castleman’s Disease with a Marked Infiltration of IgG4-Positive Cells in the Renal Interstitium

  • Erika Sawada,
  • Yuya Shioda,
  • Kohki Ogawa,
  • Takatsugu Iwashita and ,
  • Yuko Ono,
  • Hajime Hasegawa and
  • Akito Maeshima
  • + 2 authors+ 0 author

23 February 2024

Multicentric Castleman’s disease (MCD) is a benign lymphoproliferative disorder with heterogenous clinical symptoms, and involves systemic organs in addition to lymph nodes. Herein, we present the case of a 55-year-old man with MCD characterize...

(This article belongs to the Special Issue Diagnosis and Treatment of Kidney Disease)
  • Article
  • Open Access
1 Citations
3,273 Views
9 Pages

Role of 18F-FDG PET/CT in the Management of Patients Affected by HHV-8-Associated Multicentric Castleman’s Disease

  • Domenico Albano,
  • Francesco Bertagna,
  • Elisabetta Cerudelli,
  • Francesco Dondi and
  • Raffaele Giubbini

20 June 2021

Our aim was to investigate the usefulness of 18fluorine-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in the diagnosis, treatment response evaluation, and follow-up of human herpesvirus-8 (HHV-8)-associated mult...

(This article belongs to the Section Radiolabeled Blood Elements and Other Imaging Modalities)

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