Journal Menu► ▼ Journal Menu
Journal Browser► ▼ Journal Browser
Special Issue "Chronic Kidney Disease: Underlying Molecular Mechanisms"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: closed (5 October 2022) | Viewed by 13776
Special Issue Editors
Interests: toxicology; drugs of abuse; amphetamines; synthetic cathinones; psychoactive substances; toxicometabolomics; cancer metabolomics; biomarkers; hepatotoxicity; nephrotoxicity; cardiotoxicity; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Special Issue in Metabolites: Toxicometabolomics
Special Issue in Psychoactives: Clinical Pharmacology and Toxicology of Cannabis-Based Medicinal Products
Interests: inflammatory; oxidative stress; cardiovascular risk factors; insulin resistance; pre-eclampsia; chronic kidney disease; obesity
Special Issue Information
Chronic kidney disease (CKD), defined as the presence of abnormalities of kidney function or structure lasting at least three months, is an epidemic health issue that requires global attention. The global rise in the incidence of CKD has been accompanied by a general increase in human longevity as well as an increase in the traditional and non-traditional risk factors for the disease. CKD is associated with significant comorbidity and mortality, being responsible for enormous healthcare costs.
An in-depth understanding of the mechanisms of CKD’s onset and progression will enable the implementation of preventive strategies and the development of drugs that have the potential to delay the onset and/or worsening of this disease. Furthermore, proper knowledge of these mechanisms can help in the identification of early biomarkers of this disease, which is crucial for timely clinical intervention.
This Special Issue aims to cover the most recent research findings in the following areas: a) the molecular mechanisms (particularly oxidative stress and inflammation) involved in the pathophysiology of CKD and associated comorbidities; b) the use of emerging methodological approaches—including omics—for unraveling the molecular pathways in CKD and proposing new disease markers; c) mechanisms cross-linking CKD and other health issues, such as cancer, obesity, and diabetes.
Prof. Dr. Márcia Carvalho
Prof. Dr. Luís Belo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Chronic kidney disease
- molecular mechanisms
- oxidative stress