The Antarctic limpet, Nacella concinna, is one of the most abundant benthic marine invertebrates found in the intertidal zone of King George Island, Antarctica. The shell of N. concinna is often encrusted with the coralline algae Clathromorphum obtec...
The oil and gas industry faces increasing pressure to remove people from dangerous offshore environments. Robots present a cost-effective and safe method for inspection, repair, and maintenance of topside and marine offshore infrastructure. In this w...
This study was conducted to elucidate how shell form contributes to functional adaptation and mechanical optimization in seven limpet species inhabiting intertidal zones along the Korean coast. Ten morphological and weight-related parameters were mea...
Seafood is a crucial source of nutrients, with global consumption steadily increasing. Among seafood-related allergies, shellfish are a significant cause of food allergy and anaphylaxis worldwide, affecting approximately 0.5–2.5% of the general...
This study investigated the microbial diversity associated with the digestive tract of the seaweed grazing marine limpet Patella pellucida. Using a modified indirect DNA extraction protocol and performing metagenomic profiling based on specific proka...
CaCO3 spherulites were found in the myostracum layer of common limpet shells collected from East Sands, St Andrews, Scotland. Their microstructures were revealed by using powder X-ray diffraction, scanning electron microscopy, high-resolution transmi...
This study aimed to investigate a cost-effective alternative to man-made calcium phosphate ceramics for treating bone defects. The slipper limpet is an invasive species in European coastal waters, and its shells composed of calcium carbonate could po...
Keyhole limpet hemocyanin (KLH) is a large copper-containing glycoprotein derived from the marine gastropod Megathura crenulata. Originally functioning as an oxygen transport molecule, KLH has gained considerable attention in biomedical research due...
Satellite DNA (sat-DNA) was previously described as junk and selfish DNA in the cellular economy, without a clear functional role. However, during the last two decades, evidence has been accumulated about the roles of sat-DNA in different cellular fu...
Canine urothelial carcinoma (UC) is commonly managed with non-steroidal anti-inflammatory drugs (NSAIDs), alone or combined with cytotoxic chemotherapy. Evidence supporting subcutaneous keyhole limpet hemocyanin (KLH) in canine UC is lacking. We desc...
Diverse non-methylene-interrupted (NMI) fatty acids (FAs) with odd-chain lengths have been recognized in triacylglycerols and polar lipids from the ovaries of the limpet Cellana toreuma, however their biological properties remain unclear. In this stu...
Limpets are pivotal for structuring and regulating the ecological balance of littoral communities and are widely collected for human consumption and as fishing bait. Limpets of the species Patella caerulea were collected between April 2016 and April...
Seawater acidification and freshening in the intertidal zone of Marian Cove, Antarctica, which occurs by the freshwater inflow from snow fields and glaciers, could affect the physiology and behavior of intertidal marine organisms. In this study, we e...
Limpet teeth contain a desirable combination of material properties: they are auxetic (i.e., they have a negative Poisson’s ratio) and have high stiffness and strength. In contrast, synthetic auxetic structures presented in the literature to da...
Background: The giant keyhole limpet Megathura crenulata is a gastropod mollusk (Fissurella superfamily) that is endemic to the eastern Pacific coast from southern California, USA, to Baja California Sur, Mexico. M. crenulata is socioeconomically imp...
The population genetics of Patella ferruginea Gmelin, 1791, an endangered limpet endemic to the western Mediterranean, has been analysed using 11 polymorphic microsatellite markers on 533 individuals from 18 localities throughout its distribution are...
The present study aimed to describe the reproductive cycle of the black-footed limpet (Patella depressa Pennant, 1777) from an intertidal rocky shore on the Algarve coast (southern Portugal). Samples were collected monthly between January 2017 and De...
Measurement of the elemental composition of shells is increasingly emerging as an avenue for obtaining high-resolution insights into paleoclimate and past seasonality. Several studies have shown significant correlations between Mg/Ca ratios measured...
The presence of a 13-desmethyl Spirolide C isomer (Iso-13-desm SPX C) is very common in some infaunal mollusks in Galicia contaminated with this toxin. Its possible origin by biological transformation was investigated by incubating homogenates of the...
A novel polyclonal antibody against tetrodotoxin (TTX) was raised using its haptenic antigen, where 4,9-anhydroTTX was reacted with 1,2-ethanedithiol and this derivative was further reacted with keyhole limpet hemocyanin (KLH). This newly designed an...
The Mediterranean limpet (Patella caerulea, Linnaeus, 1758) is a native species in Türkiye that is not yet a major commercial species but has potential for future commercialisation, particularly given the country’s substantial mollusc expo...
We study 2D RVEs based on microstructures inspired by limpet teeth with the objective of efficiently identifying auxetic designs and building surrogates for effective elastic response. The starting point is an unbalanced database; thus, we run a weig...
A native strain of the entomopathogenic fungus Beauveria bassiana (Bb-C001) was isolated from a naturally infected Triatoma infestans, Klug (Hemiptera: Reduviidae) adult cadaver in the Gran Chaco region, Salta province, Argentina. The isolate was bot...
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Paraquat (PQ) is a toxic non-selective herbicide. To date, the effect of PQ on memory immune response is still unknown. We investigated the impact of PQ on memory immune response. Adult C57BL/6 mice were subcutaneously injected with 2 mg/kg PQ, 20 mg...
Limpets are molluscs widely used in food diet and much appreciated in many regions. The consumption of fishery products rich in polyunsaturated fatty acids has been increasing through filleted products and restructured products. Since food oxidation...
Limpets are marine gastropod molluscs well adapted to intertidal rocky environments, yet their taxonomic resolution remains challenging due to extensive morphological convergence and the presence of cryptic species. In this study, we applied an integ...
Antibacterial resistance has become a major problem where new promising drugs are needed. The extracts obtained from marine invertebrates Mytilus galloprovincialis, Patella sp., Gibbula sp. and Arbacia lixula were tested against bacteria using the di...
The seasonal availability of food for Antarctic zoobenthic consumers affects, among other factors, the levels of excreted metabolites that can serve as a source of nitrogen (N) and phosphorus (P) for autotrophs. This study tested the effects of prolo...
To further understand the origin and evolution of Patellogastropoda, we determined the mitochondrial genome sequence of Cellana toreuma, and compared its mitogenome characteristics with the other four limpets of Nacellidae. The ratio of Ka and Ks ind...
Mussel beds form important intertidal matrices that provide thermal buffering to associated invertebrate communities, especially under stressful environmental conditions. Mussel shells are often colonized by photoautotrophic euendoliths, which have i...
Aberrantly glycosylated mucin 1 (MUC1) is a recognized tumor-specific antigen on epithelial cell tumors. A wide variety of MUC1 glycopeptide anti-cancer vaccines have been formulated by many research groups. Some researchers have used MUC1 alone as a...
We have conjugated the S9 peptide, a mimic of the group B streptococcal type III capsular polysaccharide, to different carriers in an effort to elicit an optimal immune response. As carriers, we utilized the soluble protein keyhole limpet hemocyanin...
Segmentation is one of the most important stages in the 3D reconstruction of macromolecule structures in cryo-electron microscopy. Due to the variability of macromolecules and the low signal-to-noise ratio of the structures present, there is no gener...
A rapid, simple, and sensitive immunochromatographic test strip has been developed for testing residues of ciprofloxacin (CIP). A specific and sensitive monoclonal antibody (mAb) for CIP was generated by immunizing BALB/c mice with well-characterize...
Antibodies against citrinin (CTN) were generated from rabbits, which were injected with CTN-keyhole limpet hemocyanin (KLH). This work involved the development of a sensitive competitive direct enzyme-linked immunosorbent assay (cdELISA) and a rapid...
Enzyme-linked immunosorbent assay (ELISA) based on a monoclonal antibody (MoAb) was developed for the neonicotinoid insecticide clothianidin. A new clothianidin hapten (3-[5-(3-methyl-2-nitroguanidinomethyl)-1,3-thiazol-2-ylthio] propionic acid) was...
At a depth of approximately 9 m off the coast of Banderas Bay, hydrothermal activity occurs through various seabed vents, discharging liquids and gases that reach temperatures of up to 89 °C and pH values lower than the surrounding seawater. This...
This paper examines the exploitation of marine molluscs in the Western Isles of Scotland, from the Bronze Age to Norse periods (2500 BCE–1266 CE). Through analysis of shell assemblages from thirteen archaeological sites, we investigate changing...
The increasing activity in morphological studies has provided new tools to analyses the shape quantitatively, these quantitative measurements allow the researcher to examine the variation in shape and perform analysis to examine the quantitative diff...
The interactions between fungi and plants can yield metabolites that are toxic in animal systems. Certain fungi are known to produce sesquiterpenoid trichothecenes, such as T-2 toxin, that are biotransformed by several mechanisms including glucosylat...
Background: Personalized cancer vaccines based on tumor neoantigens show great potential in cancer immunotherapy due to their high safety and specificity. However, it is inherently difficult to realize the efficiently targeted delivery of personalize...
Nivalenol (NIV) is a trichothecene mycotoxin that is more toxic than deoxynivalenol. It accumulates in grains due to infection with Fusarium species, which are the causative agents of scab or Fusarium head blight. An immunoassay, which is a rapid and...
Background: Siphonaria is a genus of false limpets belonging to the Gastropoda class. Only two species of this genus have been described with mitochondrial genomes. Moreover, the codon usage patterns and factors influencing them have not been studied...
A synthetic 20 amino acid peptide of the ribosomal protein P0 from ticks, when conjugated to keyhole limpet hemocyanin from Megathura crenulata and used as an immunogen against Rhipicephalus microplus and Rhipicephalus sanguineus s.l. species, has sh...
The latest vaccination campaign has actualized the potential impact of antigenic stimuli on reproductive functions. To address this, we mimicked vaccination’s effects by administering keyhole limpet hemocyanin (KLH ) to CD1 male mice and used their s...
Humic substances and beneficial microorganisms are key biostimulants for sustainable agriculture and global food security in the face of climate change. Marine bacteria are emerging as a promising source of plant-beneficial microbes, tapping into a m...
The most advanced malaria vaccine, RTS,S, includes the central repeat and C-terminal domains of the Plasmodium falciparum circumsporozoite protein (PfCSP). We have recently isolated human antibodies that target the junctional region between the N-ter...
The malaria vaccine candidate merozoite surface protein 2 (MSP2) has shown promise in clinical trials and is in part responsible for a reduction in parasite densities. However, strain-specific reductions in parasitaemia suggested that polymorphic reg...
The consumption of shellfish contaminated with brevetoxins, a family of ladder-frame polyether toxins formed during blooms of the marine dinoflagellate Karenia brevis, can cause neurotoxic poisoning, leading to gastroenteritis and neurotoxic effects....
Genotype 4 hepatitis E virus (HEV) is a zoonotic pathogen transmitted to humans through food and water. Previously, three genotype 4 swine HEV ORF2 peptides (407EPTV410, 410VKLYTS415, and 458PSRPF462) were identified as epitopes of virus-neutralizing...
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