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309 Results Found

  • Review
  • Open Access
13 Citations
7,574 Views
13 Pages

28 May 2015

Both the US and EU have introduced pediatric pharmaceutical legislation to facilitate clinical trials in children and development of better medicines for children. The first concerns were published in 2014 that the European Medicines Agency (EMA)’s P...

(This article belongs to the Collection Development of Medicines for Paediatric and Rare Diseases)
  • Brief Report
  • Open Access
760 Views
11 Pages

The purpose of this article is to stimulate research in orofacial myology. The research-to-practice gap may be reduced by highlighting concepts relating to evidence-based practice. Information is also presented on the International Association of Oro...

  • Perspective
  • Open Access
884 Views
17 Pages

The bacterial and toxin methods of cancer treatment date back 130 years. This paradigm rests on nonspecific bacterial-toxin-generated immunotherapy. This high-risk oncology research is experiencing a renaissance of methods that are among the most eff...

(This article belongs to the Section Molecular Immunology)
  • Article
  • Open Access
48 Citations
11,654 Views
18 Pages

Ethical Considerations Related to Return of Results from Genomic Medicine Projects: The eMERGE Network (Phase III) Experience

  • Robyn Fossey,
  • David Kochan,
  • Erin Winkler,
  • Joel E. Pacyna and ,
  • Janet Olson,
  • Stephen Thibodeau,
  • John J. Connolly,
  • Margaret Harr,
  • Meckenzie A. Behr and
  • Iftikhar J. Kullo
  • + 28 authors+ 23 authors

We examined the Institutional Review Board (IRB) process at 9 academic institutions in the electronic Medical Records and Genomics (eMERGE) Network, for proposed electronic health record-based genomic medicine studies, to identify common questions an...

  • Communication
  • Open Access
27 Citations
7,413 Views
6 Pages

N-of-1 Trials: Evidence-Based Clinical Care or Medical Research that Requires IRB Approval? A Practical Flowchart Based on an Ethical Framework

  • Bas C. Stunnenberg,
  • Jaap Deinum,
  • Tom Nijenhuis,
  • Frans Huysmans and ,
  • Gert Jan van der Wilt,
  • Baziel G.M. van Engelen and
  • Frans van Agt
  • + 2 authors+ 0 author

27 February 2020

N-of-1 trials can provide high-class evidence on drug treatment effectiveness at the individual patient level and have been given renewed interest over the past decade due to improvements of the initial single patient design. Despite these recent dev...

(This article belongs to the Special Issue N-of-1 Trials in Healthcare)
  • Article
  • Open Access
4 Citations
3,909 Views
15 Pages

Cross-Platform Gait Analysis and Fall Detection Wearable Device

  • Ming-Hung Chang,
  • Yi-Chao Wu,
  • Hsi-Yu Niu,
  • Yi-Ting Chen and
  • Shu-Han Juang

4 March 2023

Since the fall was often occurred in elders daily, this paper focused on gait analysis with fall detection to develop a wearable device. To ensure that the mobile application, APP, could be used in different platform of mobile phone, such Android or...

(This article belongs to the Special Issue Intelligent Medicine and Health Care)
  • Systematic Review
  • Open Access
12 Citations
3,089 Views
14 Pages

Background: Peripheral blood level of brain-derived neurotrophic factor (BDNF) may be used as a diagnostic and/or prognostic marker for schizophrenia. Previous studies were inconsistent. A systematic review was conducted to examine whether BDNF level...

(This article belongs to the Section Neuropsychiatry)
  • Correction
  • Open Access
1 Citations
1,841 Views
1 Page

Correction: Rubiola et al. Risk Factors for Bovine Cysticercosis in North-West Italy: A Multi-Year Case-Control Study. Animals 2021, 11, 3049

  • Selene Rubiola,
  • Barbara Moroni,
  • Luca Carisio,
  • Luca Rossi and ,
  • Francesco Chiesa,
  • Giuseppe Martano,
  • Elisa Cavallo and
  • Luisa Rambozzi
  • + 3 authors+ 0 author

3 March 2022

Error in Institutional Review Board Statement [...]

(This article belongs to the Special Issue Parasitic Diseases of Cattle)
  • Correction
  • Open Access
317 Views
1 Page

Correction: Akintola et al. An Exploration of Aquatic Food Production and Marketing Mix in the Coastal States of Nigeria. Aquac. J. 2026, 6, 18

  • Shehu L. Akintola,
  • Lateef A. Badmos,
  • Akinkunmi S. Ojo,
  • Gbenga R. Ajepe and ,
  • Matthew A. Ajibade,
  • Mary A. Gbadamosi,
  • Victor T. Okomoda,
  • Idowu J. Fasakin,
  • Sunil Siriwardena and
  • Rodrigue Yossa
  • + 7 authors+ 2 authors

4 August 2026

Error in Institutional Review Board Statement and Informed Consent Statement [...]

  • Correction
  • Open Access
505 Views
1 Page

Correction: Weimer et al. Localisation-Dependent Variations in Articular Cartilage ECM: Implications for Tissue Engineering and Cartilage Repair. Int. J. Mol. Sci. 2025, 26, 9331

  • Laura Weimer,
  • Luisa M. Schmidt,
  • Gerhard Sengle,
  • Marcus Krüger and ,
  • Alan M. Smith,
  • Ilona Brändlin and
  • Frank Zaucke
  • + 2 authors+ 0 author

Missing Institutional Review Board Statement and Informed Consent Statement [...]

(This article belongs to the Section Molecular Biology)
  • Correction
  • Open Access
579 Views
1 Page

Correction: Cutti et al. The Effect of the Poly-Articulated Prosthetic Hand on Shoulder and Trunk Compensatory Movements during Manipulation and Grasp Tasks. Prosthesis 2023, 5, 182–196

  • Andrea Giovanni Cutti,
  • Federico Morosato,
  • Emanuele Gruppioni,
  • Gregorio Teti and ,
  • Lorenzo De Michieli and
  • Cosimo Gentile
  • + 1 author+ 0 author

“Institutional Review Board Statement” was not included in the original publication [...]

  • Correction
  • Open Access
1 Citations
1,606 Views
1 Page

Correction: Doss et al. Performance Evaluation of a PET of 7T Bruker Micro-PET/MR Based on NEMA NU 4-2008 Standards. Electronics 2022, 11, 2194

  • Kishore Krishnagiri Manoj Doss,
  • Pei En Mion,
  • Yu-Chieh Jill Kao,
  • Tsung-Ter Kuo and
  • Jyh-Cheng Chen

20 September 2022

In the original publication, the Institutional Review Board Statement was not included [...]

(This article belongs to the Special Issue Feature Papers in the Optoelectronics Section)
  • Correction
  • Open Access
1 Citations
2,203 Views
1 Page

Correction: Lin et al. Potent Anticancer Effects of Epidithiodiketopiperazine NT1721 in Cutaneous T Cell Lymphoma. Cancers 2021, 13, 3367

  • Min Lin,
  • Claudia M. Kowolik,
  • Jun Xie,
  • Sushma Yadav and ,
  • Larry E. Overman and
  • David A. Horne
  • + 1 author+ 0 author

7 December 2021

There is an omission in the Institutional Review Board Statement and Conflict of Interest statements of the paper [...]

  • Correction
  • Open Access
297 Views
1 Page

Correction of Institutional Review Board Statement and Informed Consent Statement in back matter [...]

  • Correction
  • Open Access
733 Views
2 Pages

Correction: Sakaloglou et al. Genomic and Epidemiological Surveillance of SARS-CoV-2 Epidemic in Northwestern Greece. Acta Microbiol. Hell. 2024, 69, 285–294

  • Prodromos Sakaloglou,
  • Petros Bozidis,
  • Konstadina Kourou,
  • Charilaos Kostoulas and ,
  • Athanasia Gouni,
  • Eleni Tsaousi,
  • Despoina Koumpouli,
  • Sofia Argyropoulou,
  • Petros Oikonomidis and
  • Konstantina Gartzonika
  • + 9 authors+ 4 authors

The Institutional Review Board Statement and Informed Consent Statement sections in the original publication [...]

  • Correction
  • Open Access
184 Views
1 Page
  • Correction
  • Open Access
400 Views
1 Page

The Institutional Review Board Statement and Informed Consent Statement need to be updated in the original publication [...]

(This article belongs to the Special Issue Spaces and Practices of Everyday Community Resilience)
  • Editorial
  • Open Access
1 Citations
1,050 Views
4 Pages

Pending the approval of the Institutional Review Boards (IRBs), researchers can access clinicians’ tools to explore the molecular phenomena affected by neurological disorders in living humans [...]

(This article belongs to the Special Issue Molecules at Play in Neurological Diseases)
  • Commentary
  • Open Access
4,026 Views
11 Pages

17 December 2021

To date, independent ethical oversight of many companion animal welfare initiatives has been limited and, in some instances, inadequate. Beyond a blurred line between “innovation” and “research,” the nature of the work conduct...

(This article belongs to the Section Animal Ethics)
  • Correction
  • Open Access
1 Citations
484 Views
1 Page

4 January 2026

The authors would like to make the following corrections in the published paper [1]: (1)Add the Institutional Review Board Statement:Ethical review and approval were waived for this study by Changsha University of Science and Technology as this resea...

  • Perspective
  • Open Access
2 Citations
8,072 Views
14 Pages

For Indigenous populations, one of the most recognized acts of historical trauma has come from boarding schools. These institutions were established by federal and state governments to forcibly assimilate Indigenous children into foreign cultures thr...

(This article belongs to the Special Issue Advances in Indigenous and American Indian and Alaska Native Health and Wellness)
  • Review
  • Open Access
1 Citations
1,138 Views
17 Pages

Optimizing Precision Oncology: Structural Frameworks for Local MTB Integration and Outcome Assessment

  • Nicoleta Zenovia Antone,
  • Flaviu Andreicovici,
  • Andrada Larisa Deac,
  • Roxana Pintican and ,
  • Maria Miclaus,
  • Adrian Pavel Trifa,
  • Andreea Catana,
  • Ovidiu Balacescu,
  • Cătălin Vlad and
  • Patriciu Achimas-Cadariu
  • + 5 authors+ 0 author

Background/Objectives: Molecular tumor profiling has recently transformed oncologic care delivery, establishing precision medicine as an essential approach for defining cancer biology and revealing intratumoral heterogeneity. The growing accessibilit...

(This article belongs to the Section Cancer and Cancer-Related Research)
  • Editorial
  • Open Access
4 Citations
11,452 Views
2 Pages

On behalf of the Editorial Board and the editorial management staff of MDPI, it is my great pleasure to introduce this new journal Geosciences. Geosciences is an international, peer-reviewed open access journal, which publishes original papers, rapid...

  • Systematic Review
  • Open Access
3 Citations
1,763 Views
16 Pages

The Experience of Frail Older Patients in the Boarding Area in the Emergency Department: A Qualitative Systematic Review

  • Pasquale Iozzo,
  • Giovanna Cannizzaro,
  • Stefano Bambi,
  • Luana Maria Amato and ,
  • Simona Fanuli,
  • Dhurata Ivziku,
  • Giuliano Anastasi,
  • Alberto Lucchini,
  • Noemi Spina and
  • Roberto Latina
  • + 5 authors+ 0 author

19 May 2025

Background/Objectives: Boarding refers to the period when patients deemed stable in the emergency department (ED) are temporarily monitored, wait to be admitted, and receive appropriate care. As life expectancy increases, so does the importance of un...

(This article belongs to the Special Issue Current Trends and Prospects of Critical Emergency Medicine)
  • Article
  • Open Access
4 Citations
4,934 Views
12 Pages

This descriptive study investigates breast thermal characteristics in females histologically diagnosed with unilateral breast cancer and in their contralateral normal breasts. The multi-institutional clinical pilot study was reviewed and approved by...

  • Communication
  • Open Access
12 Citations
3,945 Views
8 Pages

Overall Survival and Adjuvant Therapy in Women with Ovarian Carcinosarcoma: A Single-Institution Experience

  • Aaron Nizam,
  • Bethany Bustamante,
  • Weiwei Shan,
  • Karin K. Shih and ,
  • Jill S. Whyte,
  • Antoinette Sakaris,
  • Lisa dos Santos,
  • Marina Frimer,
  • Andrew W. Menzin and
  • Gary L. Goldberg
  • + 6 authors+ 1 author

Background: Carcinosarcoma of the ovary (CSO) is a rare and aggressive variant of ovarian cancer. Due to the rare nature of the disease there is insufficient evidence to make recommendations regarding standard management and overall prognosis. Method...

(This article belongs to the Special Issue Ovarian Cancer: Characteristics, Screening, Diagnosis and Treatment)
  • Review
  • Open Access
17 Citations
176 Views

Recently, there has been a resurgence of interest in potential phototherapy technologies for the local treatment of bacterial and fungal infection. Currently, onychomycosis is the principle disease that is the target of these phototherapies in podiat...

  • Article
  • Open Access
11 Citations
5 Pages

The aim of this article is to investigate a retrocaruncular approach for repairing medial orbital wall fractures. A total of 10 fresh cadaver orbits were dissected to investigate a transconjunctival approach to the orbit posterior to the caruncle. Me...

  • Review
  • Open Access
11 Citations
9,679 Views
22 Pages

We aim to provide a comprehensive systematic analysis of scholarly publications in the field of board compensation in financial sectors extending through the years 1987 to 2021. Hence, the most notable themes, theories, and contributions to the liter...

  • Article
  • Open Access
430 Views
20 Pages

Fifteen-Year Referral Trends and the Gender-Affirming Care Pathway in a Predominantly Adult Gender Dysphoria Cohort: A Retrospective Cohort Study from a University-Based Center in Türkiye

  • Hanife Yılmaz Abaylı,
  • Diğdem Göverti,
  • İlay Dalkıran,
  • Seray Sultan Karakoç and ,
  • Aila Gareayaghi,
  • Ezgi Şişman,
  • Niyazi Umut Yıldırımoğlu and
  • Aslıhan Polat
  • + 3 authors+ 0 author

22 September 2026

Background/Objectives: Most long-term cohort data on gender-affirming care come from adolescent and young adult populations in Western Europe and North America. In a Muslim-majority setting where legal gender recognition is contingent on a court ruli...

(This article belongs to the Section Mental Health and Psychosocial Well-being)
  • Review
  • Open Access
797 Views
39 Pages

Digital money has transformed from a technological experiment into a central concern of monetary economics, financial regulation, and public policy. Despite rapid growth in cryptocurrencies, stablecoins, central bank digital currencies (CBDCs), and t...

(This article belongs to the Collection Encyclopedia of Digital Society, Industry 5.0 and Smart City)
  • Editorial
  • Open Access
2 Citations
2,607 Views
3 Pages

26 October 2020

The development of high-throughput techniques has permitted the accumulation of enormous amounts of genomic information. As increasing numbers of studies aim to utilize individual genomic information for diagnostic, preventive, or therapeutic purpose...

  • Article
  • Open Access
1 Citations
5,120 Views
24 Pages

Relevant Information for the Accountability of Private Institutions of Social Solidarity: Results from Fieldwork

  • Helena Inácio,
  • Alberto J. Costa,
  • Ana Maria Bandeira,
  • Augusta Ferreira and ,
  • Brízida Tomé,
  • Carla Joaquim,
  • Carlos Santos,
  • Cristina Góis,
  • Denise Curi and
  • Rui Pedro Marques
  • + 11 authors+ 6 authors

28 January 2022

The social economy (SE) has emerged as an interesting alternative for dealing with social problems. However, there are some concerns related to the abilities of these institutions regarding accountability. Thus, the present work aimed to determine if...

  • Review
  • Open Access
502 Views
32 Pages

26 August 2026

This article reviews CFO gender as a role-specific executive diversity issue and addresses the fragmented literature in which gender effects are often interpreted without separating appointment selection from the authority and organizational context...

  • Article
  • Open Access
5 Citations
7,491 Views
20 Pages

Deploying a Mental Health Chatbot in Higher Education: The Development and Evaluation of Luna, an AI-Based Mental Health Support System

  • Phillip Olla,
  • Ashlee Barnes,
  • Lauren Elliott,
  • Mustafa Abumeeiz and ,
  • Venus Olla and
  • Joseph Tan
  • + 1 author+ 0 author

Rising mental health challenges among postsecondary students have increased the demand for scalable, ethical solutions. This paper presents the design, development, and safety evaluation of Luna, a GPT-4-based mental health chatbot. Built using a mod...

(This article belongs to the Special Issue Transformative Approaches in Education: Harnessing AI, Augmented Reality, and Virtual Reality for Innovative Teaching and Learning)
  • Protocol
  • Open Access
3 Citations
2,781 Views
18 Pages

Navigating Gender-Affirming Healthcare in Adverse Political Climates: Experience from a University-Based Transgender Clinic in Türkiye

  • Aslıhan Polat,
  • Hanife Yılmaz Abaylı,
  • İlay Dalkıran,
  • Aila Gareayaghi and ,
  • Seray Karakoç,
  • Nezihe Gül,
  • Zeynep Büyükkaraca,
  • Ezgi Şişman,
  • Seher Kocaayan and
  • Seher Şirin
  • + 17 authors+ 12 authors

14 October 2025

Background/Objectives: Gender-affirming care is a complex, multidisciplinary process that has gained increasing recognition worldwide. This practice report presents the unique clinical model developed at the Kocaeli University Hospital Gender Dysphor...

(This article belongs to the Special Issue Psychology in Sex and Gender)
  • Article
  • Open Access
1,369 Views
12 Pages

Development and Validation of a Consensus-Based Checklist for Regional Anesthesia: The LRA Checklist as a Tool for Safety, Standardization, and Value-Based Care

  • Antonio Clemente,
  • Domenico Pietro Santonastaso,
  • Mario Bosco,
  • Fabio Costa and ,
  • Grazia De Angelis,
  • Romualdo Del Buono,
  • Fabio Gori,
  • Giuseppe Lubrano,
  • Valeria Mossetti and
  • Fabrizio Fattorini
  • + 14 authors+ 9 authors

Background: Regional anesthesia is a fundamental aspect of contemporary perioperative care. However, variability in practice, incomplete documentation, and inconsistent safety protocols continue to pose preventable risks. Although there are internati...

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