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45 Results Found

  • Communication
  • Open Access
1,937 Views
11 Pages

3 January 2025

A low-power, high-speed adder circuit topology based on current-starved inverters is presented to provide a basic arithmetic function for low-power, high-frequency signal processing systems. The adder is designed in 22 nm FDSOI (Fully-Depleted Silico...

  • Article
  • Open Access
2,046 Views
21 Pages

The coupling capacitor of the MTP cell used in this paper is an NCAP-type capacitor that has only a source contact, and the layout size of the unit cell is 6.184 μm × 6.295 μm (=38.93 μm2), which is 0.44% smaller than the MTP cell that...

  • Proceeding Paper
  • Open Access
11 Citations
9,962 Views
9 Pages

Design of Efficient Phase Locked Loop for Low Power Applications

  • Chandra Keerthi Pothina,
  • Ngangbam Phalguni Singh,
  • Jagupilla Lakshmi Prasanna,
  • Chella Santhosh and
  • Mokkapati Ravi Kumar

13 March 2023

The phase-locked loop is a technique that has contributed significantly to technological advancements in many applications in the fast-evolving digital era. In this paper, a Phase Locked Loop (PLL) is designed using 90 nm CMOS technology node with 1....

  • Article
  • Open Access
12 Citations
6,070 Views
10 Pages

25 November 2016

Outbreaks of the coral-eating crown-of-thorns seastar (Acanthaster cf. solaris) threaten coral reefs of the Indo-Pacific. Movement patterns may play an important role in the spread of outbreak populations, but studies investigating adult movement beh...

  • Article
  • Open Access
17 Citations
4,116 Views
14 Pages

Food Restriction in Mice Induces Food-Anticipatory Activity and Circadian-Rhythm-Related Activity Changes

  • Theo Gabloffsky,
  • Sadaf Gill,
  • Anna Staffeld,
  • Ralf Salomon,
  • Nicole Power Guerra,
  • Sarah Joost,
  • Alexander Hawlitschka,
  • Markus Kipp and
  • Linda Frintrop

9 December 2022

Anorexia nervosa (AN) is characterized by emaciation, hyperactivity, and amenorrhea. To what extent AN-related symptoms are due to food restriction or neuronal dysfunction is currently unknown. Thus, we investigated the relevance of food restriction...

  • Article
  • Open Access
23 Citations
3,994 Views
11 Pages

Correlation between Mechanical Properties and Processing Conditions in Rubber-Toughened Wood Polymer Composites

  • Valentina Mazzanti,
  • Lorenzo Malagutti,
  • Andrea Santoni,
  • Francesca Sbardella,
  • Andrea Calzolari,
  • Fabrizio Sarasini and
  • Francesco Mollica

20 May 2020

The use of wood fibers is a deeply investigated topic in current scientific research and one of their most common applications is as filler for thermoplastic polymers. The resulting material is a biocomposite, known as a Wood Polymer Composite (WPC)....

  • Proceeding Paper
  • Open Access
1 Citations
2,230 Views
5 Pages

As the scale of computations become large and as both people and machines demand communication, collaboration and commerce at the speed of light, rapid fluctuations in the demand for computing performance and fluctuations in available resource pools,...

  • Feature Paper
  • Article
  • Open Access
2,976 Views
12 Pages

Increasing EMI Immunity and Linearity of a CMOS 180 nm Voltage-to-Delay Converter

  • Anna Richelli,
  • Luigi Colalongo and
  • Federico Angelo Bosio

This paper presents a voltage-controlled delay unit (VCDU) with a novel architecture allowing for a wide input range of linearity and an improved immunity to electromagnetic interferences. The circuit is based on a current-starved inverter with a bia...

  • Feature Paper
  • Article
  • Open Access
4 Citations
3,448 Views
14 Pages

Sensitive, Linear, Robust Current-To-Time Converter Circuit for Vehicle Automation Application

  • Nandakishor Yadav,
  • Youngbae Kim,
  • Mahmoud Alashi and
  • Kyuwon Ken Choi

Voltage-to-time and current-to-time converters have been used in many recent works as a voltage-to-digital converter for artificial intelligence applications. In general, most of the previous designs use the current-starved technique or a capacitor-b...

  • Article
  • Open Access
5 Citations
3,136 Views
10 Pages

28 September 2020

This paper presents a time domain CMOS temperature sensor with a simple current source. This sensor chip only occupies a small active die area of 0.026 mm2 because it adopts a simple current source consisting of an n-type poly resistor and a PMOS tra...

  • Article
  • Open Access
16 Citations
12,531 Views
16 Pages

A 0.2 V, 23 nW CMOS Temperature Sensor for Ultra-Low-Power IoT Applications

  • Divya Akella Kamakshi,
  • Aatmesh Shrivastava and
  • Benton H. Calhoun

We propose a fully on-chip CMOS temperature sensor in which a sub-threshold (sub-VT) proportional-to-absolute-temperature (PTAT) current element starves a current-controlled oscillator (CCO). Sub-VT design enables ultra-low-power operation of this te...

  • Review
  • Open Access
8 Citations
3,037 Views
14 Pages

23 November 2023

Angiogenesis has been associated with numbers of solid tumours. Anti-angiogenesis drugs starve tumours of nutrients and oxygen but also make it difficult for a chemo reagent to distribute into a tumour, leading to aggressive tumour growth. Anti-angio...

  • Communication
  • Open Access
2 Citations
4,026 Views
9 Pages

A low-power delay-locked loop (DLL)-based frequency multiplier is presented. The multiplier is designed in 22 nm FDSOI and achieves 8× multiplication. The proposed DLL uses a new simple duty cycle correction circuit and is XOR logic-based for f...

  • Review
  • Open Access
4 Citations
2,828 Views
26 Pages

25 September 2024

The majority of bearings in the world are lubricated by grease, and nearly 80% of premature bearing damage is attributed to lubrication issues. Accurate measurement and prediction of film thickness are crucial aspects of understanding the lubrication...

  • Article
  • Open Access
17 Citations
6,505 Views
14 Pages

Starch Rich Chlorella vulgaris: High-Throughput Screening and Up-Scale for Tailored Biomass Production

  • Giorgia Carnovale,
  • Filipa Rosa,
  • Volha Shapaval,
  • Simona Dzurendova,
  • Achim Kohler,
  • Trude Wicklund,
  • Svein Jarle Horn,
  • Maria J. Barbosa and
  • Kari Skjånes

28 September 2021

The use of microalgal starch has been studied in biorefinery frameworks to produce bioethanol or bioplastics, however, these products are currently not economically viable. Using starch-rich biomass as an ingredient in food applications is a novel wa...

  • Feature Paper
  • Article
  • Open Access
5 Citations
5,980 Views
16 Pages

26 January 2022

Understanding the development of shallow seas is essential, as they provide a major environmental and economic resource. An investigation of the Holocene development and the present conditions of the Andaman Sea shelf was carried out based on hydroac...

  • Article
  • Open Access
6 Citations
4,482 Views
10 Pages

A Sensitive Potentiometric Sensor for Isothermal Amplification-Coupled Detection of Nucleic Acids

  • Kang-Ho Lee,
  • Dongkyu Lee,
  • Jongsu Yoon,
  • Ohwon Kwon and
  • Jaejong Lee

14 July 2018

A disposable potentiometric sensor was newly developed for the amplification-coupled detection of nucleic acids. The hydrogen-ion is generally released during isothermal amplification of nucleic acids. The surface potential on the oxide-functionalize...

  • Article
  • Open Access
9 Citations
3,767 Views
17 Pages

A 6.89-MHz 143-nW MEMS Oscillator Based on a 118-dBΩ Tunable Gain and Duty-Cycle CMOS TIA

  • Ahmed Kira,
  • Mohannad Y. Elsayed,
  • Karim Allidina,
  • Vamsy P. Chodavarapu and
  • Mourad N. El-Gamal

29 October 2021

This article presents a 6.89 MHz MEMS oscillator based on an ultra-low-power, low-noise, tunable gain/duty-cycle transimpedance amplifier (TIA) and a bulk Lamé-mode MEMS resonator that has a quality factor (Q) of 3.24 × 106. Self-cascoding and curren...

  • Review
  • Open Access
20 Citations
5,080 Views
20 Pages

Elucidating the Multi-Targeted Role of Nutraceuticals: A Complementary Therapy to Starve Neurodegenerative Diseases

  • Tapan Behl,
  • Gagandeep Kaur,
  • Aayush Sehgal,
  • Sukhbir Singh,
  • Saurabh Bhatia,
  • Ahmed Al-Harrasi,
  • Gokhan Zengin,
  • Simona Gabriela Bungau,
  • Mihai Alexandru Munteanu and
  • Ciprian Brisc
  • + 2 authors

The mechanisms underlying multifactorial diseases are always complex and challenging. Neurodegenerative disorders (NDs) are common around the globe, posing a critical healthcare issue and financial burden to the country. However, integrative evidence...

  • Article
  • Open Access
4 Citations
3,978 Views
15 Pages

18 February 2021

An ultralow-power ultrawideband (UWB) transmitter with an energy-efficient injection-locked radio frequency (RF) clock harvester that generates a carrier from an RF signal is proposed for RF energy-harvesting Internet-of-Things (IoT) sensor applicati...

  • Article
  • Open Access
7 Citations
4,481 Views
16 Pages

27 September 2019

When plants are exposed to sulfur limitation, they upregulate the sulfate assimilation pathway at the expense of growth-promoting measures. Upon cessation of the stress, however, protective measures are deactivated, and growth is restored. In accorda...

  • Article
  • Open Access
7 Citations
2,987 Views
21 Pages

18 July 2019

In internal combustion engines (ICEs), the frictional performance of ring-liner conjunction (RLC) has drawn special attention because it greatly affects the fuel efficiency of the engines. In recent years, surface texture (i.e., micro dimples or groo...

  • Article
  • Open Access
11 Citations
3,615 Views
12 Pages

10 July 2021

Parasitoids are currently considered for biological control of the spotted wing drosophila (SWD) in berry crops. Releases of mass-reared parasitoids require the presence of all resources necessary to ensure their effectiveness in the crop system. The...

  • Article
  • Open Access
2 Citations
3,367 Views
15 Pages

Functional Whole Genome Screen of Nutrient-Starved Mycobacterium tuberculosis Identifies Genes Involved in Rifampin Tolerance

  • William M. Matern,
  • Harley T. Harris,
  • Carina Danchik,
  • Marissa McDonald,
  • Gopi Patel,
  • Aashish Srivastava,
  • Thomas R. Ioerger,
  • Joel S. Bader and
  • Petros C. Karakousis

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), poses a global health challenge and is responsible for over a million deaths each year. Current treatment is lengthy and complex, and new, abbreviated regimens are urgently n...

  • Review
  • Open Access
4 Citations
5,433 Views
28 Pages

8 November 2024

TinyML/DL is a new subfield of ML that allows for the deployment of ML algorithms on low-power devices to process their own data. The lack of resources restricts the aforementioned devices to running only inference tasks (static TinyML), while traini...

  • Article
  • Open Access
7 Citations
7,839 Views
21 Pages

14 February 2019

Many aspects of the present and future effects on the UK economy, industry, and households, of Brexit have been researched. One thing which appears certain about Brexit is the shadow of uncertainty it casts on the future of business in the UK and its...

  • Article
  • Open Access
4 Citations
1,933 Views
12 Pages

The high precision and low power consumption of the clock generator are critical in passive RFID transponders and passive IoT chips, but fluctuations in PVT can cause considerable degradation in the precision of the chip’s internal clocks. This...

  • Article
  • Open Access
3 Citations
2,842 Views
25 Pages

7 March 2024

Cisplatin, a powerful chemotherapy medication, has long been a cornerstone in the fight against cancer due to chemotherapeutic failure. The mechanism of cisplatin resistance/failure is a multifaceted and complex issue that consists mainly of apoptosi...

  • Article
  • Open Access
7 Citations
7,521 Views
12 Pages

22 January 2017

This paper presents a fully integrated on-chip switched-capacitor (SC) DC–DC converter that supports a programmable regulated power supply ranging from 2.6 to 3.2 V out of a 5 V input supply. The proposed 4-to-3 step-down topology utilizes two conven...

  • Article
  • Open Access
5 Citations
3,608 Views
14 Pages

Dps proteins (DNA-binding proteins from starved cells) are multifunctional stress defense proteins from the Ferritin family expressed in Prokarya during starvation and/or acute oxidative stress. Besides shielding bacterial DNA through binding and con...

  • Article
  • Open Access
6 Citations
2,051 Views
13 Pages

25 November 2024

This paper introduces a novel TRNG architecture that employs a wave converter to generate random outputs from the jitter noise in a customized ring oscillator (RO). Using a current-starved inverter, the proposed RO offers the option of operating thre...

  • Article
  • Open Access
34 Citations
6,189 Views
13 Pages

Stationary-Phase Mutagenesis in Stressed Bacillus subtilis Cells Operates by Mfd-Dependent Mutagenic Pathways

  • Martha Gómez-Marroquín,
  • Holly A. Martin,
  • Amber Pepper,
  • Mary E. Girard,
  • Amanda A. Kidman,
  • Carmen Vallin,
  • Ronald E. Yasbin,
  • Mario Pedraza-Reyes and
  • Eduardo A. Robleto

5 July 2016

In replication-limited cells of Bacillus subtilis, Mfd is mutagenic at highly transcribed regions, even in the absence of bulky DNA lesions. However, the mechanism leading to increased mutagenesis through Mfd remains currently unknown. Here, we repor...

  • Article
  • Open Access
44 Citations
5,826 Views
21 Pages

Phosphorus Feast and Famine in Cyanobacteria: Is Luxury Uptake of the Nutrient Just a Consequence of Acclimation to Its Shortage?

  • Alexei Solovchenko,
  • Olga Gorelova,
  • Olga Karpova,
  • Irina Selyakh,
  • Larisa Semenova,
  • Olga Chivkunova,
  • Olga Baulina,
  • Elizaveta Vinogradova,
  • Tatiana Pugacheva and
  • Elena Lobakova
  • + 3 authors

21 August 2020

To cope with fluctuating phosphorus (P) availability, cyanobacteria developed diverse acclimations, including luxury P uptake (LPU)—taking up P in excess of the current metabolic demand. LPU is underexplored, despite its importance for nutrient...

  • Review
  • Open Access
2 Citations
8,617 Views
16 Pages

PDK2: An Underappreciated Regulator of Liver Metabolism

  • Benjamin L. Woolbright and
  • Robert A. Harris

11 May 2021

Pyruvate metabolism is critical for all mammalian cells. The pyruvate dehydrogenase complex couples the pyruvate formed as the primary product of glycolysis to the formation of acetyl-CoA required as the primary substrate of the citric acid cycle. Dy...

  • Article
  • Open Access
8 Citations
2,354 Views
15 Pages

Natural Fatty Acid Guards against Brain Endothelial Cell Death and Microvascular Pathology following Ischemic Insult in the Presence of Acute Hyperglycemia

  • Zaib Ali Shaheryar,
  • Mahtab Ahmad Khan,
  • Huma Hameed,
  • Muhammad Naveed Mushtaq,
  • Sajjad Muhammad,
  • Gamal A. Shazly,
  • Ali Irfan and
  • Yousef A. Bin Jardan

18 December 2023

Ischemic stroke is worsened by the presence of sudden high blood sugar levels, even in individuals without pre-existing diabetes. This elevated glucose concentration hampers the ability of energy-starved brain cells to efficiently use it as a source...

  • Article
  • Open Access
20 Citations
5,498 Views
24 Pages

Observed Changes of a Mega Feeder Nourishment in a Coastal Cell: Five Years of Sand Engine Morphodynamics

  • Bart Roest,
  • Sierd de Vries,
  • Matthieu de Schipper and
  • Stefan Aarninkhof

Recently, mega feeder nourishments have been proposed as a new strategy to nourish sediment-starving beaches. This strategy involves the placement of a large, concentrated sediment volume at a single location along the coast. Wind, waves and currents...

  • Article
  • Open Access
2 Citations
2,541 Views
13 Pages

Subaqueous Topographic Deformation in Abandoned Delta Lobes—A Case Study in the Yellow River Delta, China

  • Yunfeng Zhang,
  • Yingying Chai,
  • Caiping Hu,
  • Yijun Xu,
  • Yuyan Zhou,
  • Huanliang Chen,
  • Zijun Li,
  • Shenting Gang and
  • Shuwei Zheng

28 May 2023

Reduction in river discharge and sediment load has left deltaic lobes in the world’s many river deltas starving, but knowledge of how the subaqueous topography of these abandoned subdeltas responds to environmental changes is limited. In this study,...

  • Article
  • Open Access
17 Citations
9,246 Views
26 Pages

Scenario-Based Analysis on Water Resources Implication of Coal Power in Western China

  • Jiahai Yuan,
  • Qi Lei,
  • Minpeng Xiong,
  • Jingsheng Guo and
  • Changhong Zhao

16 October 2014

Currently, 58% of coal-fired power generation capacity is located in eastern China, where the demand for electricity is strong. Serious air pollution in China, in eastern regions in particular, has compelled the Chinese government to impose a ban on...

  • Review
  • Open Access
453 Views
15 Pages

16 January 2026

Background: Organ transplant offers patients a second chance at life, yet chronic rejection remains a formidable barrier to long-term success. Unlike the instantaneous storm of acute rejection, chronic rejection is a slow, unremitting process that si...

  • Article
  • Open Access
78 Citations
10,349 Views
18 Pages

Melatonin Effects on Non-Alcoholic Fatty Liver Disease Are Related to MicroRNA-34a-5p/Sirt1 Axis and Autophagy

  • Alessandra Stacchiotti,
  • Ilaria Grossi,
  • Raquel García-Gómez,
  • Gaurangkumar Arvindbhai Patel,
  • Alessandro Salvi,
  • Antonio Lavazza,
  • Giuseppina De Petro,
  • Maria Monsalve and
  • Rita Rezzani

8 September 2019

Melatonin, an indole produced by pineal and extrapineal tissues, but also taken with a vegetarian diet, has strong anti-oxidant, anti-inflammatory and anti-obesogenic potentials. Non-alcoholic fatty liver disease (NAFLD) is the hepatic side of the me...

  • Article
  • Open Access
24 Citations
6,363 Views
11 Pages

23 January 2018

Authentication is a crucial security service for the wireless sensor networks (WSNs) in versatile domains. The deployment of WSN devices in the untrusted open environment and the resource-constrained nature make the on-chip authentication an open cha...

  • Article
  • Open Access
5 Citations
3,787 Views
11 Pages

19 September 2022

(1) Background: Rapid sequence induction (RSI) is carried out by anaesthetists to secure the airway promptly in patients who are at risk of aspirating gastric content during induction of anaesthesia. RSI requires variation in the paediatric populatio...

  • Article
  • Open Access
11 Citations
3,793 Views
16 Pages

Bioactivities and Mode of Actions of Dibutyl Phthalates and Nocardamine from Streptomyces sp. H11809

  • Fauze Mahmud,
  • Ngit Shin Lai,
  • Siew Eng How,
  • Jualang Azlan Gansau,
  • Khairul Mohd Fadzli Mustaffa,
  • Chiuan Herng Leow,
  • Hasnah Osman,
  • Hasidah Mohd Sidek,
  • Noor Embi and
  • Ping-Chin Lee

31 March 2022

Dibutyl phthalate (DBP) produced by Streptomyces sp. H11809 exerted inhibitory activity against human GSK-3β (Hs GSK-3β) and Plasmodiumfalciparum 3D7 (Pf 3D7) malaria parasites. The current study aimed to determine DBP’s plausible mod...

  • Review
  • Open Access
4 Citations
1,945 Views
30 Pages

28 August 2025

Wood–plastic composites (WPCs) are polymeric materials, usually thermoplastic, filled with wood flour or fibers. They are relatively durable and stiff and resistant to water. They are also, importantly, relatively cheap compared to materials wi...

  • Article
  • Open Access
1 Citations
2,279 Views
14 Pages

In recent years, significant progress has been made in China in the field of deep-sea large yellow croaker (Larimichthys crocea) farming. Compared with the traditional inshore aquaculture model, deep-sea culture of large yellow croaker enjoys a wider...