A Sensitive Potentiometric Sensor for Isothermal Amplification-Coupled Detection of Nucleic Acids
Abstract
:1. Introduction
2. Materials and Methods
2.1. Device Structure and First-Order Model of the Device
2.2. Design of an FET Sensor with a Ring Oscillator Circuit
2.3. Functionalized Electrodes and Electrical Readout Circuits
2.4. Extraction and Amplification of Nucleic Acids
3. Results
3.1. Performance of the Designed Sensor
3.2. Isothermal Amplification of Nucleic Acids
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Lee, K.-H.; Lee, D.; Yoon, J.; Kwon, O.; Lee, J. A Sensitive Potentiometric Sensor for Isothermal Amplification-Coupled Detection of Nucleic Acids. Sensors 2018, 18, 2277. https://doi.org/10.3390/s18072277
Lee K-H, Lee D, Yoon J, Kwon O, Lee J. A Sensitive Potentiometric Sensor for Isothermal Amplification-Coupled Detection of Nucleic Acids. Sensors. 2018; 18(7):2277. https://doi.org/10.3390/s18072277
Chicago/Turabian StyleLee, Kang-Ho, Dongkyu Lee, Jongsu Yoon, Ohwon Kwon, and Jaejong Lee. 2018. "A Sensitive Potentiometric Sensor for Isothermal Amplification-Coupled Detection of Nucleic Acids" Sensors 18, no. 7: 2277. https://doi.org/10.3390/s18072277