Comparative analysis of the conventional methylation-specific PCR (MSP) vs. the quantitative MSP (qMSP) assessment of the O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation status in 34 snap-frozen (SF) glioma samples was performed. T...
Bovine anaplasmosis is a tick-borne disease caused by an obligate intercellular Gram-negative bacterium named Anaplasma (A.) marginale. In this study, we report the seasonal prevalence, potentially associated risk factors and phylogeny of A. marginal...
Background: Understanding the genetic structure of P. falciparum population in different regions is pivotal to malaria elimination. Genetic diversity and the multiplicity of infection are indicators used for measuring malaria endemicity across differ...
MSP1 is a Magnaporthe oryzae secreted protein that elicits defense responses in rice. However, the molecular mechanism of MSP1 action is largely elusive. Moreover, it is yet to be established whether MSP1 functions as a pathogen-associated molecular...
The measurement of recent malaria exposure can support malaria control efforts. This study evaluated serological responses to an in-house Plasmodium vivax Merozoite Surface Protein 8 (PvMSP8) expressed in a Baculovirus system as sero-marker of recent...
Anaplasma ovis is a tick-borne obligated intraerythrocytic bacterium that infects domestic sheep, goats, and wild ruminants. Recently, several studies have been carried out using 16S rRNA and msp4 genes to identify the genetic diversity of A. ov...
In order to obtain the structural intensity under the operation conditions of MSP (molten salt pump), the rotor component of MSP is taken as the research object. In this paper, the influence of material properties change on the structural performance...
This study examines the relationship between institutional resource allocation to Multicultural Student Programs and Services (MSPS) and the retention rates of students of color at public higher education institutions as operationalized by the Unit P...
Anaplasma phagocytophilum, a tick-borne Rickettsiales, causes an emerging disease among humans and animals called granulocytic anaplasmosis. The organism expresses an immunodominant surface protein, MSP2/P44, that undergoes rapid antigenic variation...
The Arabidopsis multistep-phosphorelay (MSP) is a signaling mechanism based on a phosphorelay that involves three different types of proteins: Histidine kinases, phosphotransfer proteins, and response regulators. Its bacterial equivalent, the two-com...
Vesicle-associated membrane protein (VAMP)-associated protein B (VAPB) serves as a tethering factor that interacts with various proteins and recruits these proteins to the ER surface, exerting multiple functions, such as organelle membrane tethering,...
Malaria remains a significant public health challenge, particularly in endemic regions. The extensive genetic diversity of Plasmodium falciparum (Pf) complicates outbreak prediction and transmission control. One of its most polymorphic markers, meroz...
Transdermal immunization exhibits poor immunogenic responses due to poor permeability of antigens through the skin. Elastic liposomes, the ultradeformable nanoscale lipid vesicles, overcome the permeability issues and prove a versatile nanocarrier fo...
A non-zero correlation between service times can be encountered in many real queueing systems. An attractive model for correlated service times is the Markovian service process, because it offers powerful fitting capabilities combined with analytical...
The COVID-19 pandemic has necessitated profound changes in the business and technology landscapes, compelling organizations to reassess their Enterprise Resource Planning (ERP) systems. Traditional ERP systems have demonstrated significant limitation...
Plasmodium malariae has a wide geographic distribution, but mainly at very low parasitemias and in co-infections, leading to an underestimated prevalence of this species. Studies for the detection of antibodies against Plasmodium recombinant proteins...
Background: The serological tests using blood stage antigens might be helpful for detecting recent exposure to Plasmodium parasites, and seroepidemiological studies would aid in the elimination of malaria. This work produced recombinant proteins of P...
Vaccines are highly effective tools against infectious diseases and are also considered necessary in the fight against malaria. Vaccine-induced immunity is frequently mediated by antibodies. We have recently conducted a first-in-human clinical trial...
We study waiting times in a queue with active management and correlated job/packet sizes, which induce correlated service times. In the transient case, formulae for the distribution tail, the probability density, and the expected virtual waiting time...
Ambient Intelligence (AmI) requires devices everywhere, dynamic and massively distributed networks of low-cost nodes that, among other data, manage private information or control restricted operations. MSP430, a 16-bit microcontroller, is used in WSN...
7 September 2025
Understanding Plasmodium falciparum population genetic diversity is crucial to assess the impact of malaria control interventions. This study investigated P. falciparum genetic diversity using merozoite surface protein 1 (msp1), msp2 and glutamate-ri...
The paper focuses on Maritime Spatial Planning (MSP) and the importance of incorporating participatory democracy and inclusivity, from a region-wise perspective. Traditionally MSP is a top-down (central government) process. Most responsibilities, com...
High levels of genetic variants of Plasmodium vivax have previously been reported in Thailand. Circumsporozoite surface protein (CSP), merozoite surface protein (MSP), and microsatellite markers were used to determine the genetic polymorphisms of P. ...
Compatibility of each strain in a multi-strain probiotic (MSP), along with its properties, becomes a strong base for its formulation. In this study, single-strain probiotics (SSPs) and multi-strain probiotics (MSPs) were evaluated in vitro for strain...
The 2014 EU Directive on Maritime Spatial Planning (MSP) lays down obligations for the EU Member States to establish a maritime planning process, resulting in a maritime spatial plan by 2020. Consultation should be carried out with local, national an...
Background and Objective: In the first trimester of pregnancy, fetal growth, and abnormalities can be assessed using the exact middle sagittal plane (MSP) of the fetus. However, the ultrasound (US) image quality and operator experience affect the acc...
A single-institution observational study with 43 newly diagnosed diffuse gliomas defined the isocitrate dehydrogenase 1 and 2 (IDH1/2) gene mutation status and evaluated the prognostic relevance of the methylation status of the epigenetic marker O6-m...
9 January 2025
The COVID-19 pandemic led to a rapid shift to remote working, which affected ergonomic conditions and increased the risk of upper body musculoskeletal pain (MSP). This study assessed the prevalence and impact of upper body MSP (affecting the head, ne...
Biomarkers for the classification of rheumatoid arthritis (RA), and particularly for anti-citrullinated peptide antibody (ACPA)-negative patients, remain an important hurdle for the early initiation of treatment. Taking advantage of DNA-methylation p...
It was demonstrated that the mechanical shot peening (MSP) technique was a viable way to obtain a nanocrystalline layer on a large size pure titanium plate due to the MSP provided for severe plastic deformation (SPD) of surface high velocity balls im...
European strategic policy directions toward a sustainable blue economy have strengthened interest in maritime investments, thus increasing sectoral competition for marine space. Emerging repercussions out of such a rising interest need to be handled...
Recycled concrete incorporating additional super-absorbent polymer (SAP) and machine-made stone powder (MSP) was prepared using a two-factor, four-level orthogonal test. To enhance the frost resistance of recycled concrete and improve its mechanical...
In early 2021, the Erasmus+ knowledge flows partnership organised a session to discuss the future of marine spatial planning (MSP) at an international conference. We, a group of nine early career researchers, came together after the conference to con...
Bovine anaplasmosis is endemic in South Africa and it has a negative economic impact on cattle farming. An improved understanding of Anaplasma marginale and Anaplasma marginale variety centrale (A. centrale) transmission, together with improved tools...
The multiple anthropogenic activities taking place in the marine environment increase and create a high demand for maritime space. The pressures generated thereof on coastal and marine resources require an integrated planning and management approach....
This paper introduces smart marine ecosystem-based planning (SMEP), a marine spatial planning (MSP) strategy for more participatory and responsive marine governance by leveraging “smart” digital services. SMEP denotes an iterative MSP pro...
Nesprin-1 is a large scaffold protein connecting nuclei to the actin cytoskeleton via its KASH and Calponin Homology domains, respectively. Nesprin-1 disconnection from nuclei results in altered muscle function and myonuclei mispositioning. Furthermo...
Plasmodium parasites’ invasion of their target cells is a complex, multi-step process involving many protein-protein interactions. Little is known about how complex the interaction with target cells is in Plasmodium vivax and few surface molecules re...
In this paper, we present the first constant-time implementations of four-dimensional Gallant–Lambert–Vanstone and Galbraith–Lin–Scott (GLV-GLS) scalar multiplication using curve - on 8-bit AVR, 16-bi...
Background and Objective. A T-to-C polymorphism that creates a recognition site for the MspA1 restriction enzyme in the 5’ promoter region of CYP17 has been implicated as a risk factor for prostate cancer. To date, many studies have evaluated associa...
We have previously identified proteins in poplar which belong to an osmosensing (OS) signaling pathway, called a multistep phosphorelay (MSP). The MSP comprises histidine-aspartate kinases (HK), which act as membrane receptors; histidine phosphotrans...
DNA methylation is an epigenetic modification of the genome, with methylation-based biomarkers showing promise for cancer detection. Quantitative Methylation-Specific PCR (qMSP) is widely used to assess DNA methylation; however, its application to li...
In the context of carbon peaking and carbon neutrality (“double carbon”), it is urgent to clarify the effect of marine spatial planning (MSP) on carbon sink increases and emission reductions, since such planning acts as a spatial governan...
Multi-sided platforms (MSPs) can enable multiple user groups to create coordinated value. Like all transformative business models, these platforms emerged to resolve platform-related issues. Among the well-known MSPs, this research has focused on the...
Spatial tools to calculate cumulative impact assessments on the environment (CIA) are important contributors to the implementation of an ecosystem-based approach to maritime spatial planning (MSP). Ecosystem dynamics are increasingly important to und...
Managed Service Providers (MSPs) have increasingly become prime targets for cyberattacks due to their privileged access across multiple client environments. Utilizing a qualitative thematic synthesis and an Open-Source Intelligence (OSINT) methodolog...
Italy and Slovenia have recently adopted their first Maritime Spatial Plans (MSP). These plans belong to a new generation of spatial planning acts that introduce numerous innovations. This article presents the differences and similarities between the...
Background: Diversity in Plasmodium falciparum poses a major threat to malaria control and elimination interventions. This study utilized 12 polymorphic microsatellite (MS) markers and the Msp2 marker to examine diversity, multiplicity of infection (...
Valosin-containing protein (VCP) gene mutations have been associated with a rare autosomal dominant, adult-onset progressive disease known as multisystem proteinopathy 1 (MSP1), or inclusion body myopathy (IBM), Paget’s disease of bone (PDB), f...
Virus-like particles (VLP) are a highly efficient vaccine platform used to present multiple antigenic proteins. Merozoite surface protein 8 (MSP-8), 9 (MSP-9) and rhoptry-associated protein 1 (RAP1) of Plasmodium berghei are the important proteins in...
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