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  • Article
  • Open Access
2,652 Views
32 Pages

Construction of a Structurally Unbiased Brain Template with High Image Quality from MRI Scans of Saudi Adult Females

  • Noura Althobaiti,
  • Kawthar Moria,
  • Lamiaa Elrefaei,
  • Jamaan Alghamdi and
  • Haythum Tayeb

In brain mapping, structural templates derived from population-specific MRI scans are essential for normalizing individual brains into a common space. This normalization facilitates accurate group comparisons and statistical analyses. Although templa...

(This article belongs to the Section Biosignal Processing)
  • Article
  • Open Access
48 Citations
5,196 Views
16 Pages

Refined Automatic Brain Tumor Classification Using Hybrid Convolutional Neural Networks for MRI Scans

  • Fatma E. AlTahhan,
  • Ghada A. Khouqeer,
  • Sarmad Saadi,
  • Ahmed Elgarayhi and
  • Mohammed Sallah

23 February 2023

Refined hybrid convolutional neural networks are proposed in this work for classifying brain tumor classes based on MRI scans. A dataset of 2880 T1-weighted contrast-enhanced MRI brain scans are used. The dataset contains three main classes of brain...

(This article belongs to the Special Issue Artificial Intelligence for Magnetic Resonance Imaging)
  • Article
  • Open Access
12 Citations
4,827 Views
16 Pages

Blockchain-Based Deep CNN for Brain Tumor Prediction Using MRI Scans

  • Farah Mohammad,
  • Saad Al Ahmadi and
  • Jalal Al Muhtadi

Brain tumors are nonlinear and present with variations in their size, form, and textural variation; this might make it difficult to diagnose them and perform surgical excision using magnetic resonance imaging (MRI) scans. The procedures that are curr...

(This article belongs to the Special Issue Medical Image Processing and Analysis)
  • Article
  • Open Access
47 Citations
3,826 Views
20 Pages

Within-Modality Synthesis and Novel Radiomic Evaluation of Brain MRI Scans

  • Seyed Masoud Rezaeijo,
  • Nahid Chegeni,
  • Fariborz Baghaei Naeini,
  • Dimitrios Makris and
  • Spyridon Bakas

10 July 2023

One of the most common challenges in brain MRI scans is to perform different MRI sequences depending on the type and properties of tissues. In this paper, we propose a generative method to translate T2-Weighted (T2W) Magnetic Resonance Imaging (MRI)...

(This article belongs to the Special Issue Role of Novel Imaging Technique in Brain Tumors)
  • Article
  • Open Access
5 Citations
3,497 Views
15 Pages

Generation of Synthetic Rat Brain MRI Scans with a 3D Enhanced Alpha Generative Adversarial Network

  • André Ferreira,
  • Ricardo Magalhães,
  • Sébastien Mériaux and
  • Victor Alves

11 May 2022

Translational brain research using Magnetic Resonance Imaging (MRI) is becoming increasingly popular as animal models are an essential part of scientific studies and more ultra-high-field scanners are becoming available. Some disadvantages of MRI are...

(This article belongs to the Section Computing and Artificial Intelligence)
  • Article
  • Open Access
4 Citations
4,735 Views
15 Pages

In-scanner head motion often leads to degradation in MRI scans and is a major source of error in diagnosing brain abnormalities. Researchers have explored various approaches, including blind and nonblind deconvolutions, to correct the motion artifact...

(This article belongs to the Special Issue Deep Learning in Medical Image Analysis, Volume II)
  • Article
  • Open Access
16 Citations
3,346 Views
28 Pages

14 January 2026

This work presents the development and evaluation of Artificial Intelligence (AI) models for the automatic classification of brain tumors in Magnetic Resonance Imaging (MRI) scans. Several deep learning architectures were implemented and compared, in...

(This article belongs to the Section Applied Biosciences and Bioengineering)
  • Article
  • Open Access
12 Citations
4,477 Views
24 Pages

8 July 2022

In this paper, we propose a novel squeeze M-SegNet (SM-SegNet) architecture featuring a fire module to perform accurate as well as fast segmentation of the brain on magnetic resonance imaging (MRI) scans. The proposed model utilizes uniform input pat...

(This article belongs to the Section Biomedical Sensors)
  • Article
  • Open Access
29 Citations
4,629 Views
20 Pages

21 December 2022

Accurately identifying tumors from MRI scans is of the utmost importance for clinical diagnostics and when making plans regarding brain tumor treatment. However, manual segmentation is a challenging and time-consuming process in practice and exhibits...

(This article belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)
  • Article
  • Open Access
1 Citations
4,118 Views
19 Pages

26 December 2023

With the advancements in neuroimaging techniques, understanding the relationship between brain morphology and behavioral tendencies such as criminal behavior has garnered interest. This research addresses the investigation of disparities in neuroanat...

  • Article
  • Open Access
90 Citations
8,503 Views
17 Pages

Exploring the Power of Deep Learning: Fine-Tuned Vision Transformer for Accurate and Efficient Brain Tumor Detection in MRI Scans

  • Abdullah A. Asiri,
  • Ahmad Shaf,
  • Tariq Ali,
  • Unza Shakeel and ,
  • Muhammad Irfan,
  • Khlood M. Mehdar,
  • Hanan Talal Halawani,
  • Ali H. Alghamdi,
  • Abdullah Fahad A. Alshamrani and
  • Samar M. Alqhtani
  • + 5 authors+ 0 author

A brain tumor is a significant health concern that directly or indirectly affects thousands of people worldwide. The early and accurate detection of brain tumors is vital to the successful treatment of brain tumors and the improved quality of life of...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
7 Citations
1,407 Views
19 Pages

Introduction: Brain tumor, marked by abnormal and rapid cell growth, poses severe health risks and requires accurate diagnosis for effective treatment. Classifying brain tumors using deep learning techniques applied to Magnetic Resonance Imaging (MRI...

(This article belongs to the Special Issue Machine Learning in Precise and Personalized Diagnosis)
  • Article
  • Open Access
2 Citations
3,672 Views
18 Pages

15 October 2024

As an alternative to true isotropic 3D imaging, image super-resolution (SR) has been applied to reconstruct an isotropic 3D volume from multiple anisotropic scans. However, traditional SR methods struggle with inadequate performance, prolonged proces...

(This article belongs to the Special Issue Multi-Source Image Fusion, Restoration, and Understanding and Its Application in Sensing)
  • Article
  • Open Access
49 Citations
8,484 Views
16 Pages

The accurate segmentation of brain tumors from medical images is critical for diagnosis and treatment planning. However, traditional segmentation methods struggle with complex tumor shapes and inconsistent image quality which leads to suboptimal resu...

(This article belongs to the Special Issue Biomedical Imaging and Data Analytics for Disease Diagnosis and Treatment, 2nd Edition)
  • Article
  • Open Access
10 Citations
3,498 Views
21 Pages

Brain Tumor Classification in MRI Scans Using Edge Computing and a Shallow Attention-Guided CNN

  • Niraj Anil Babar,
  • Junayd Lateef,
  • ShahNawaz Syed,
  • Julia Dietlmeier and ,
  • Noel E. O’Connor,
  • Gregory B. Raupp and
  • Andreas Spanias
  • + 2 authors+ 0 author

Background/Objectives: Brain tumors arise from abnormal, uncontrolled cell growth due to changes in the DNA. Magnetic Resonance Imaging (MRI) is vital for early diagnosis and treatment planning. Artificial intelligence (AI), especially deep learning,...

(This article belongs to the Special Issue Advances in Brain Tumor Diagnosis: Innovations and Emerging Technologies)
  • Article
  • Open Access
9 Citations
4,937 Views
21 Pages

14 August 2023

In this study, an automated medical decision support system is presented to assist physicians with accurate and immediate brain tumor detection, segmentation, and volume estimation from MRI which is very important in the success of surgical operation...

(This article belongs to the Section E: Life Sciences)
  • Systematic Review
  • Open Access
12 Citations
8,482 Views
41 Pages

Brain-Computer Interfaces and AI Segmentation in Neurosurgery: A Systematic Review of Integrated Precision Approaches

  • Sayantan Ghosh,
  • Padmanabhan Sindhujaa,
  • Dinesh Kumar Kesavan,
  • Balázs Gulyás and
  • Domokos Máthé

Background: BCI and AI-driven image segmentation are revolutionizing precision neurosurgery by enhancing surgical accuracy, reducing human error, and improving patient outcomes. Methods: This systematic review explores the integration of AI technique...

  • Review
  • Open Access
11,689 Views
13 Pages

Status of Brain Imaging in Gastroparesis

  • Zorisadday Gonzalez and
  • Richard W. McCallum

The pathophysiology of nausea and vomiting in gastroparesis is complicated and multifaceted involving the collaboration of both the peripheral and central nervous systems. Most treatment strategies and studies performed in gastroparesis have focused...

(This article belongs to the Special Issue Gastroparesis)
  • Article
  • Open Access
1 Citations
898 Views
21 Pages

2 December 2025

The design of an accurate cross-domain model for Alzheimer disease AD classification from MRI scans faces critical challenges, including domain shifts caused by acquisition protocol variations. To address this issue, we propose a novel unsupervised t...

(This article belongs to the Section Human–Computer Interactions)
  • Article
  • Open Access
28 Citations
6,299 Views
12 Pages

MRI Brain Classification Using the Quantum Entropy LBP and Deep-Learning-Based Features

  • Ali M. Hasan,
  • Hamid A. Jalab,
  • Rabha W. Ibrahim,
  • Farid Meziane and ,
  • Ala’a R. AL-Shamasneh and
  • Suzan J. Obaiys
  • + 1 author+ 0 author

15 September 2020

Brain tumor detection at early stages can increase the chances of the patient’s recovery after treatment. In the last decade, we have noticed a substantial development in the medical imaging technologies, and they are now becoming an integral p...

(This article belongs to the Special Issue Exploring the NP-Complexity of Nature: Critical Phenomena, Chaos, Fractals, Graphs, Boson Sampling, Quantum Computing and More)
  • Article
  • Open Access
10 Citations
4,408 Views
17 Pages

Clinical and Radiological Profiles of COVID-19 Patients with Neurological Symptomatology: A Comparative Study

  • Maria de Fatima Viana Vasco Aragao,
  • Mariana de Carvalho Leal,
  • Pedro Henrique Pereira Andrade,
  • Ocelio Queiroga Cartaxo Filho and ,
  • Lucas Vasco Aragao,
  • Tatiana Moreira Fonseca,
  • Marcelo Andrade Valenca,
  • Maria Regina Vendas Carneiro Leao,
  • Joao Pedro Vasco Aragao and
  • Marcelo Moraes Valenca
  • + 8 authors+ 3 authors

6 May 2021

Patients with COVID-19 can require radiological examination, with chest CT being more frequent than neuro-imaging. The objective is to identify epidemiological, clinical and radiological factors considered as predictors of neurological involvement in...

(This article belongs to the Special Issue COVID-19—Advances in Clinical and Epidemiological Aspects)
  • Article
  • Open Access
2 Citations
4,027 Views
13 Pages

Non-Optic Glioma-like Lesions in Adult Neurofibromatosis Type 1 Patients

  • Walter Taal,
  • Bart Zick,
  • Bart J. Emmer and
  • Martin J. van den Bent

Background/Objectives: Physicians face clinical dilemmas in the diagnosis of non-optic intraparenchymal lesions on MRI brain scans of patients with neurofibromatosis type 1. As the incidence and evolution of these lesions into adulthood remain unclea...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
1 Citations
2,304 Views
14 Pages

First Clinical Experiences with the Ultra-Fast Time-of-Flight BIOGRAPH One Next-Generation Hybrid PET/MRI System

  • Otto M. Henriksen,
  • Kirsten Korsholm,
  • Annika Loft,
  • Johanna M. Hall and ,
  • Annika R. Langkilde,
  • Vibeke A. Larsen,
  • Thomas S. Kristensen,
  • Caroline Ewertsen,
  • Frederikke E. Høi-Hansen and
  • Ian Law
  • + 9 authors+ 4 authors

Objective: We present the first clinical experience with the BIOGRAPH One next-generation PET/MRI system scanner, evaluating its performance for body and brain imaging in patients across multiple tracers. Methods: A total of 59 patients were scanned...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
6 Citations
4,892 Views
15 Pages

A Causal Analysis of the Effect of Age and Sex Differences on Brain Atrophy in the Elderly Brain

  • Jaime Gómez-Ramírez,
  • Miguel A. Fernández-Blázquez and
  • Javier J. González-Rosa

12 October 2022

We studied how brain volume loss in old age is affected by age, the APOE gene, sex, and the level of education completed. The quantitative characterization of brain volume loss at an old age relative to a young age requires—at least in principl...

(This article belongs to the Section Radiobiology and Nuclear Medicine)
  • Article
  • Open Access
6 Citations
5,139 Views
21 Pages

Brain Extraction Methods in Neonatal Brain MRI and Their Effects on Intracranial Volumes

  • Tânia F. Vaz,
  • Nuno Canto Moreira,
  • Lena Hellström-Westas,
  • Nima Naseh and ,
  • Nuno Matela and
  • Hugo A. Ferreira
  • + 1 author+ 0 author

6 February 2024

Magnetic resonance imaging (MRI) plays an important role in assessing early brain development and injury in neonates. When using an automated volumetric analysis, brain tissue segmentation is necessary, preceded by brain extraction (BE) to remove non...

(This article belongs to the Special Issue Methods, Applications and Developments in Biomedical Informatics)
  • Article
  • Open Access
70 Citations
7,768 Views
19 Pages

Handcrafted Deep-Feature-Based Brain Tumor Detection and Classification Using MRI Images

  • Prakash Mohan,
  • Sathishkumar Veerappampalayam Easwaramoorthy,
  • Neelakandan Subramani,
  • Malliga Subramanian and
  • Sangeetha Meckanzi

14 December 2022

An abnormal growth of cells in the brain, often known as a brain tumor, has the potential to develop into cancer. Carcinogenesis of glial cells in the brain and spinal cord is the root cause of gliomas, which are the most prevalent type of primary br...

(This article belongs to the Special Issue Artificial Intelligence in Healthcare: Theory, Methods and Applications)
  • Article
  • Open Access
6 Citations
3,409 Views
13 Pages

Brain Extraction Using Active Contour Neighborhood-Based Graph Cuts Model

  • Shaofeng Jiang,
  • Yu Wang,
  • Xuxin Zhou,
  • Zhen Chen and
  • Suhua Yang

4 April 2020

The extraction of brain tissue from brain MRI images is an important pre-procedure for the neuroimaging analyses. The brain is bilaterally symmetric both in coronal plane and transverse plane, but is usually asymmetric in sagittal plane. To address t...

  • Article
  • Open Access
32 Citations
4,919 Views
16 Pages

In the domain of radiological diagnostics, accurately detecting and classifying brain tumors from magnetic resonance imaging (MRI) scans presents significant challenges, primarily due to the complex and diverse manifestations of tumors in these scans...

(This article belongs to the Special Issue Revolutionizing Medical Image Analysis with Deep Learning)
  • Article
  • Open Access
20 Citations
5,486 Views
12 Pages

Magnetic Resonance Imaging Findings in Infants with Severe Traumatic Brain Injury and Associations with Abusive Head Trauma

  • Nikki Miller Ferguson,
  • Susan Rebsamen,
  • Aaron S. Field,
  • Jose M. Guerrero and ,
  • Bedda L. Rosario,
  • Aimee T. Broman,
  • Paul J. Rathouz,
  • Michael J. Bell,
  • Andrew L. Alexander and
  • Peter A. Ferrazzano
  • + 5 authors+ 0 author

21 July 2022

Young children with severe traumatic brain injury (TBI) have frequently been excluded from studies due to age and/or mechanism of injury. Magnetic resonance imaging (MRI) is now frequently being utilized to detect parenchymal injuries and early cereb...

(This article belongs to the Special Issue Pediatric Neurocritical Care and Neurotrauma Recovery)
  • Case Report
  • Open Access
1 Citations
4,643 Views
12 Pages

Distinguishing between tumefactive demyelinating lesions (TDLs) and brain tumors in multiple sclerosis (MS) can be challenging. A progressive course is highly common with brain tumors in MS and no single neuroimaging technique is foolproof when disti...

  • Article
  • Open Access
22 Citations
5,694 Views
14 Pages

Diagnosis of Intracranial Tumors via the Selective CNN Data Modeling Technique

  • Vinayak Singh,
  • Mahendra Kumar Gourisaria,
  • Harshvardhan GM,
  • Siddharth Swarup Rautaray and ,
  • Manjusha Pandey,
  • Manoj Sahni,
  • Ernesto Leon-Castro and
  • Luis F. Espinoza-Audelo
  • + 3 authors+ 0 author

11 March 2022

A brain tumor occurs in humans when a normal cell turns into an aberrant cell inside the brain. Primarily, there are two types of brain tumors in Homo sapiens: benign tumors and malignant tumors. In brain tumor diagnosis, magnetic resonance imaging (...

(This article belongs to the Section Applied Biosciences and Bioengineering)
  • Article
  • Open Access
4 Citations
3,256 Views
27 Pages

Effect of Magnetic Resonance Image Quality on Structural and Functional Brain Connectivity: The Maastricht Study

  • Joost J. A. de Jong,
  • Jacobus F. A. Jansen,
  • Laura W. M. Vergoossen,
  • Miranda T. Schram and ,
  • Coen D. A. Stehouwer,
  • Joachim E. Wildberger,
  • David E. J. Linden and
  • Walter H. Backes
  • + 3 authors+ 0 author

In population-based cohort studies, magnetic resonance imaging (MRI) is vital for examining brain structure and function. Advanced MRI techniques, such as diffusion-weighted MRI (dMRI) and resting-state functional MRI (rs-fMRI), provide insights into...

(This article belongs to the Section Neurotechnology and Neuroimaging)
  • Feature Paper
  • Article
  • Open Access
1 Citations
1,581 Views
14 Pages

Brain Volume Measures in Adults with MOG-Antibody-Associated Disease: A Longitudinal Multicenter Study

  • Riccardo Orlandi,
  • Sara Mariotto,
  • Francesca Gobbin,
  • Francesca Rossi and ,
  • Valentina Camera,
  • Massimiliano Calabrese,
  • Francesca Calabria and
  • Alberto Gajofatto
  • + 3 authors+ 0 author

3 April 2025

Background/Objectives: Little is known about the impact of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) on brain atrophy. This multicenter longitudinal study compares brain MRI volumes and T2 lesion volume between MOGAD pat...

(This article belongs to the Special Issue Multiple Sclerosis and Demyelinating Diseases: Diagnosis, Treatment and Prognosis)
  • Article
  • Open Access
55 Citations
5,827 Views
20 Pages

Grade Classification of Tumors from Brain Magnetic Resonance Images Using a Deep Learning Technique

  • Saravanan Srinivasan,
  • Prabin Selvestar Mercy Bai,
  • Sandeep Kumar Mathivanan,
  • Venkatesan Muthukumaran and ,
  • Jyothi Chinna Babu and
  • Lucia Vilcekova
  • + 1 author+ 0 author

To improve the accuracy of tumor identification, it is necessary to develop a reliable automated diagnostic method. In order to precisely categorize brain tumors, researchers developed a variety of segmentation algorithms. Segmentation of brain image...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
78 Citations
23,831 Views
21 Pages

18 November 2016

Brain tumor segmentation in magnetic resonance imaging (MRI) is considered a complex procedure because of the variability of tumor shapes and the complexity of determining the tumor location, size, and texture. Manual tumor segmentation is a time-con...

(This article belongs to the Special Issue Symmetry in Complex Networks II)
  • Article
  • Open Access
33 Citations
4,358 Views
13 Pages

Dosimetric Validation of a GAN-Based Pseudo-CT Generation for MRI-Only Stereotactic Brain Radiotherapy

  • Vincent Bourbonne,
  • Vincent Jaouen,
  • Clément Hognon,
  • Nicolas Boussion and ,
  • François Lucia,
  • Olivier Pradier,
  • Julien Bert,
  • Dimitris Visvikis and
  • Ulrike Schick
  • + 4 authors+ 0 author

3 March 2021

Purpose: Stereotactic radiotherapy (SRT) has become widely accepted as a treatment of choice for patients with a small number of brain metastases that are of an acceptable size, allowing for better target dose conformity, resulting in high local cont...

(This article belongs to the Special Issue Cancer Radiotherapy)
  • Article
  • Open Access
16 Citations
1,522 Views
9 Pages

Language Mapping Using T2-Prepared BOLD Functional MRI in the Presence of Large Susceptibility Artifacts—Initial Results in Patients With Brain Tumor and Epilepsy

  • Jun Hua,
  • Xinyuan Miao,
  • Shruti Agarwal,
  • Chetan Bettegowda and ,
  • Alfredo Quiñones-Hinojosa,
  • John Laterra,
  • Peter C. M. Van Zijl,
  • James J. Pekar and
  • Jay J. Pillai
  • + 4 authors+ 0 author

1 June 2017

At present, presurgical functional mapping is the most prevalent clinical application of functional magnetic resonance imaging (fMRI). Signal dropouts and distortions caused by susceptibility effects in the current standard echo planar imaging (EPI)-...

  • Article
  • Open Access
54 Citations
4,620 Views
17 Pages

A Robust End-to-End Deep Learning-Based Approach for Effective and Reliable BTD Using MR Images

  • Naeem Ullah,
  • Mohammad Sohail Khan,
  • Javed Ali Khan,
  • Ahyoung Choi and
  • Muhammad Shahid Anwar

6 October 2022

Detection of a brain tumor in the early stages is critical for clinical practice and survival rate. Brain tumors arise in multiple shapes, sizes, and features with various treatment options. Tumor detection manually is challenging, time-consuming, an...

(This article belongs to the Special Issue The Convergence of Artificial Intelligence, Sensor and System for Sustainable E-healthcare Services and Biomedical Applications)
  • Article
  • Open Access
36 Citations
5,684 Views
12 Pages

Transfer-Learning Approach for Enhanced Brain Tumor Classification in MRI Imaging

  • Amarnath Amarnath,
  • Ali Al Bataineh and
  • Jeremy A. Hansen

Background: Intracranial neoplasm, often referred to as a brain tumor, is an abnormal growth or mass of tissues in the brain. The complexity of the brain and the associated diagnostic delays cause significant stress for patients. This study aims to e...

(This article belongs to the Section Computational Biology and Medicine)
  • Article
  • Open Access
24 Citations
5,588 Views
9 Pages

16 December 2020

Hypoxic-ischemic encephalopathy (HIE) is a severe neonatal complication with up to 40–60% long-term morbidity. This study evaluates the distribution and burden of MRI changes as a prognostic indicator of neurodevelopmental (ND) outcomes at 18&n...

(This article belongs to the Section Neurotechnology and Neuroimaging)
  • Article
  • Open Access
18 Citations
4,662 Views
22 Pages

Neurologic Injury and Brain Growth in the Setting of Long-Gap Esophageal Atresia Perioperative Critical Care: A Pilot Study

  • Samuel S. Rudisill,
  • Jue T. Wang,
  • Camilo Jaimes,
  • Chandler R. L. Mongerson and ,
  • Anne R. Hansen,
  • Russell W. Jennings and
  • Dusica Bajic
  • + 2 authors+ 0 author

17 December 2019

We previously showed that infants born with long-gap esophageal atresia (LGEA) demonstrate clinically significant brain MRI findings following repair with the Foker process. The current pilot study sought to identify any pre-existing (PRE-Foker proce...

(This article belongs to the Section Developmental Neuroscience)
  • Article
  • Open Access
2 Citations
2,932 Views
27 Pages

A Unified Deep Learning Framework for Robust Multi-Class Tumor Classification in Skin and Brain MRI

  • Mohamed A. Sayedelahl,
  • Ahmed G. Gad,
  • Reham M. Essa,
  • Zakaria G. Hussein and
  • Amr A. Abohany

Early detection of cancer is critical for effective treatment, particularly for aggressive malignancies like skin cancer and brain tumors. This research presents an integrated deep learning approach combining augmentation, segmentation, and classific...

(This article belongs to the Special Issue Application of Artificial Intelligence in Medical Image Analysis)
  • Article
  • Open Access
9 Citations
2,713 Views
9 Pages

Prevalence of Brain Incidental Lesions Detected by 68Ga-DOTA Peptides PET/CT

  • Domenico Albano,
  • Giorgio Treglia,
  • Francesco Dondi and
  • Francesco Bertagna

10 July 2022

Background and Objectives: 68Ga-DOTA peptides positron emission tomography/computed tomography (PET/CT) is usually applied for the study of neuroendocrine tumours, but other tumours such as meningioma may also have an increased radiopharmaceutical up...

(This article belongs to the Section Neurology)
  • Article
  • Open Access
37 Citations
12,048 Views
20 Pages

23 April 2021

The diagnosis of brain pathologies usually involves imaging to analyze the condition of the brain. Magnetic resonance imaging (MRI) technology is widely used in brain disorder diagnosis. The image quality of MRI depends on the magnetostatic field str...

(This article belongs to the Section Physical Sensors)
  • Article
  • Open Access
5 Citations
3,051 Views
12 Pages

In current research processes, mathematical learning has significantly impacted the brain’s plasticity and cognitive functions. While biochemical changes in brain have been investigated by magnetic resonance spectroscopy, our study attempts to...

(This article belongs to the Section Educational Neuroscience)
  • Article
  • Open Access
3 Citations
2,269 Views
10 Pages

How Can Specialist Advice Influence the Neuroimaging Practice for Childhood Headache in Emergency Department?

  • Alberto M. Cappellari,
  • Gaia Bruschi,
  • Gisella B. Beretta,
  • Maria T. Molisso and
  • Giuseppe Bertolozzi

22 November 2023

Differentiating between primary and secondary headaches can be challenging, especially in the emergency department (ED). Since symptoms alone are inadequate criteria for distinguishing between primary and secondary headaches, many children with heada...

(This article belongs to the Special Issue Pediatric Headaches: Diagnostic and Therapeutic Issues)
  • Article
  • Open Access
5 Citations
3,258 Views
22 Pages

A Case for Automated Segmentation of MRI Data in Neurodegenerative Diseases: Type II GM1 Gangliosidosis

  • Connor J. Lewis,
  • Jean M. Johnston,
  • Precilla D’Souza,
  • Josephine Kolstad and ,
  • Christopher Zoppo,
  • Zeynep Vardar,
  • Anna Luisa Kühn,
  • Ahmet Peker,
  • Zubir S. Rentiya and
  • Maria T. Acosta
  • + 9 authors+ 4 authors

Background: Volumetric analysis and segmentation of magnetic resonance imaging (MRI) data is an important tool for evaluating neurological disease progression and neurodevelopment. Fully automated segmentation pipelines offer faster and more reproduc...

  • Article
  • Open Access
11 Citations
3,897 Views
17 Pages

Effects of Different Scan Duration on Brain Effective Connectivity among Default Mode Network Nodes

  • Nor Shafiza Abdul Wahab,
  • Noorazrul Yahya,
  • Ahmad Nazlim Yusoff,
  • Rozman Zakaria and ,
  • Jegan Thanabalan,
  • Elza Othman,
  • Soon Bee Hong,
  • Ramesh Kumar Athi Kumar and
  • Hanani Abdul Manan
  • + 4 authors+ 0 author

Background: Resting-state functional magnetic resonance imaging (rs-fMRI) can evaluate brain functional connectivity without requiring subjects to perform a specific task. This rs-fMRI is very useful in patients with cognitive decline or unable to re...

(This article belongs to the Topic Medical Image Analysis)
  • Article
  • Open Access
10 Citations
2,178 Views
18 Pages

Hybrid of VGG-16 and FTVT-b16 Models to Enhance Brain Tumors Classification Using MRI Images

  • Eman M. Younis,
  • Ibrahim A. Ibrahim,
  • Mahmoud N. Mahmoud and
  • Abdullah M. Albarrak

12 August 2025

Background: The accurate classification of brain tumors from magnetic resonance imaging (MRI) scans is pivotal for timely clinical intervention, yet remains challenged by tumor heterogeneity, morphological variability, and imaging artifacts. Methods:...

(This article belongs to the Special Issue Deep Learning and Multimodal Large Language Models in Tumor/Cancer Diagnosis, Prediction and Prognosis)
  • Article
  • Open Access
3 Citations
1,624 Views
13 Pages

Automatic Brain Tumor Segmentation in 2D Intra-Operative Ultrasound Images Using Magnetic Resonance Imaging Tumor Annotations

  • Mathilde Gajda Faanes,
  • Ragnhild Holden Helland,
  • Ole Solheim,
  • Sébastien Muller and
  • Ingerid Reinertsen

16 October 2025

Automatic segmentation of brain tumors in intra-operative ultrasound (iUS) images could facilitate localization of tumor tissue during the resection surgery. The lack of large annotated datasets limits the current models performances. In this paper,...

(This article belongs to the Special Issue Progress and Challenges in Biomedical Image Analysis—2nd Edition)

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