Biallelic loss of function of IMPA1 causes autosomal recessive intellectual developmental disorder 59 (MRT59, OMIM #617323). MRT59 has been reported to present with significant intellectual disability and disruptive behavior, but little is known abou...
Although mTOR inhibitors have been approved as first-line therapy for treating metastatic clear cell renal cell carcinoma (ccRCC), the lack of useful markers reduces their therapeutic effectiveness. The objective of this study was to estimate if inos...
Well-known methods for seismic performance assessment, such as incremental dynamic analysis (IDA), multi-stripes analysis (MSA) and the cloud method, involve nonlinear response time-history analyses to characterize the relationship between the chosen...
Background: The aim of this study was to evaluate the correlation between skeletal class and morphological patterns of the mandibular symphysis. Methods: The sample consisted of 90 patients with an average age of 18 years (44 > x > 12). In orde...
Background: Temporary anchorage devices (TADs) have reduced the need for anterior segmental osteotomy (ASO) in Class I patients; however, ASO remains relevant in Class II patients. As previous studies were conducted before the usage of TADs, updated...
Deep learning (DL) networks have shown attractive performance in medical image processing tasks such as brain tumor classification. However, they are often criticized as mysterious “black boxes”. The opaqueness of the model and the reason...
Background and Objectives: Milk with A2/A2 β-casein (A2 milk) is currently the subject of numerous studies on the effects of its consumption on health. Commonly consumed milk contains a mixture of β-casein of different genetic variants (mos...
The article presents an innovative design solution of a balanced vane pump integrated with an electric motor that has been developed by the authors. The designed and constructed bench, which enables testing of the system: power supply, converter, nte...
In greenhouse nurseries, one of the important tasks of the automatic transplanter is replanting missing or bad seedling holes with healthy seedlings. This requires the transplanter to spend significant time moving between the supply trays and target...
Although several studies have focused on the adaptations provided by inspiratory muscle (IM) training on physical demands, the warm-up or pre-activation (PA) of these muscles alone appears to generate positive effects on physiological responses and p...
Thoracic radiography and abdominal ultrasonography are part of standard diagnostic investigations in cases of canine immune-mediated polyarthritis (IMPA). However, the clinical importance of thoracic and abdominal imaging towards the management of ca...
Immune-mediated polyarthritis (IMPA) has a relatively high relapse rate compared to other immune-mediated diseases. Leflunomide is frequently used to treat dogs with IMPA in conjunction with prednisolone. This retrospective cohort study aimed to eval...
Accurate photovoltaic (PV) output power forecasting is essential for reliable power system operation, yet rapidly changing meteorological conditions often degrade forecasting accuracy. This study proposes an attention-enhanced bidirectional gated rec...
Accurately identifying industrial loads helps to accelerate the construction of new power systems and is crucial to today’s smart grid development. Therefore, this paper proposes an industrial load classification method based on two-stage featu...
The aim of this study was to analyse if bracket systems could affect the incisors’ decompensation in a group of patients affected by dentoskeletal Class III malocclusion and on the duration of presurgical orthodontics. A single-centre retrospec...
(1) Background and aim: The effects of functional therapies on dentoalveolar and skeletal structures have been investigated in orthodontics for many years. The aim of this retrospective study was to evaluate the changes caused by fixed and removable...
Objectives: This study used fractal dimension (FD) analysis to evaluate alveolar trabecular changes associated with gingival recessions in the mandibular incisor-canine and premolar regions in the post-orthodontic retention period, compare them to no...
Background/Objectives: Clinical intraoral photographs are important for orthodontic diagnosis, treatment planning, and documentation. This study aimed to evaluate deep learning algorithms trained utilizing actual cephalometric measurements for the cl...
Autonomous underwater vehicles (AUVs) have obtained extensive application in the exploitation of marine resources. Terrain-aided navigation (TAN), as an accurate and reliable autonomous navigation method, is commonly used for AUV navigation. However,...
Cellular nucleocytoplasmic trafficking is mediated by the importin family of nuclear transport proteins. The well-characterized importin alpha (IMPA) and importin beta (IMPB) nuclear import pathway plays a crucial role in the innate immune response t...
Fusarium head blight (FHB), mainly caused by Fusarium graminearum, is one of the most destructive fungal diseases of wheat (Triticum aestivum L.). Because of the quantitative nature of FHB resistance, its mechanism is poorly understood. We conducted...
In the present study, the incremental modal pushover analysis (IMPA), a pushover-based approach already proposed and applied to buildings by the same authors, was revised and proposed for bridges (IMPAβ). Pushover analysis considers the effects...
A wireless sensor network (WSN) is a distributed network system composed of a great many sensor nodes that rely on self-organization. The random deployment of WSNs in city planning often leads to the problem of low coverage of monitoring areas. In th...
Load frequency control (LFC) serves as a crucial component of automatic generation control in renewable energy power systems. Its primary objective is to maintain a balance between the output power of generators and the load demand, thereby ensuring...
Dried urine spot (DUS) is a micro-sample collection technique, known for its advantages in handling, storage and shipping. It also uses only a small volume of urine, an essential consideration in working with small animals, or in acute medical situat...
Objective: This paper aimed to assess the effectiveness of the Rapid Maxillary Expander (RME) II System, compared to the Sander bite-jumping appliance (SBJ) and an untreated control group, in the treatment of Class II skeletal malocclusion in childre...
(1) The aim was to evaluate the predictability of treatment outcomes using clear aligner therapy (CAT) and ClinCheck Web 1.4 (Align Technology, Inc., San Jose, CA, USA) software in mandibular incisor intrusion in both children and adults with deep bi...
The objectives of this study were to assess gingival recessions (GR) and periodontal status in patients previously treated with non-extraction orthodontic treatment and retention at a follow-up of a minimum of two years after the end of treatment. Da...
(1) Background: The objective of this study was to evaluate the efficacy of the Rapid Maxillary Expander (RME) II System compared to a Herbst appliance and a control group in the treatment of class II skeletal malocclusions in growing patients. (2) M...
In this work, the microwave-assisted reaction of 5-hydroxymethylfurfural (5-HMF) into valuable ether and acylated production formation was investigated with the help of molybdophosphoric acid encapsulated dendritic fibrous silica (KCC-1) as a catalys...
Malocclusion and morphological abnormalities of the jawbone often affect the stomatognathic function and long-term postoperative stability in patients with jaw deformities. There are few reports on the effect of maximum tongue pressure (MTP) in these...
Background: This present retrospective study aimed to introduce Lower Incisor—Pg and to assess how this new parameter varies with the skeletal sagittal and vertical relationships. Methods: A total of 1256 cephalometric analyses were performed u...
2 July 2025
Understanding consumer behavior in digital environments is increasingly becoming crucial. This study investigates the influence of key metaverse characteristics—sociability, immersiveness, and environmental fidelity—on continuance intenti...
Widespread contamination of deoxynivalenol (DON) in cereals and feed threatens global food safety. This study investigated the effects of Chlorogenic acid (CGA) and VX765 on DON-induced enterohepatic injury. A total of 48 female mice were divided int...
Background: One of the goals of orthodontic treatment is to obtain maximum facial harmony. The sagittal position of the lower incisors plays a significant role in the planning of orthodontic treatment. The aim of the study was to evaluate the relatio...
COVID-19 is the most impacting global pandemic of all time, with over 600 million infected and 6.5 million deaths worldwide, in addition to an unprecedented economic impact. Despite the many advances in scientific knowledge about the disease, much re...
Background and Objectives: The objective of this retrospective controlled study is to compare class II growing patients who underwent treatment with two different functional appliances: the Fraenkel regulator (FR-2), utilized as the control group, an...
Intermittent fasting (IF) has emerged as a promising strategy for managing obesity and related metabolic disorders. Although metabolic adaptations in adipose tissue during IF are well documented, the specific reprogramming of white adipose tissue (WA...
Background: The majority of Class II malocclusions stem from mandibular deficiency, leading to chin retrusion. In growing patients, the ideal correction—aiming for a skeletal mandibular response—should avoid common pitfalls such as &ldquo...
This study systematically evaluates the impact of sensor configuration, body location, classification granularity, and model choice on inertial-based human activity recognition in a laboratory dataset aligned with the Spanish IMPaCT cohort design. Da...
29 June 2021
Background: To compare the skeletal, dental, and esthetic changes produced by three functional devices, Fränkel-2 appliance (FR-2), Twin Block (TB), and Occlus-o-Guide® (O-o-G®), for the treatment of Class II malocclusion. Methods: Sixty-five patient...
Objective: To evaluate changes in maxillary incisor inclination before and after orthodontic treatment in adults with different vertical facial patterns (normodivergent, hypodivergent, hyperdivergent) and to assess the relationship of incisor inclina...
Background and Objectives: Accurate prediction of lip prominence changes following orthodontic treatment remains challenging because traditional profile analyses rely on isolated reference lines that do not account for combined nasal and chin morphol...
Pharyngeal airway morphology is closely linked to craniofacial development, and children with Class II malocclusion—often characterized by mandibular retrusion—may present reduced airway dimensions and a higher risk of obstructive sleep a...
COVID-19 occurs due to infection through respiratory droplets containing the SARS-CoV-2 virus, which are released when someone sneezes, coughs, or talks. The gold-standard exam to detect the virus is Real-Time Polymerase Chain Reaction (RT-PCR); howe...
(1) Objectives: The purpose of this review was to compare the effects of combining skeletal anchorage and Class II devices, both from an overall perspective and individually for each type of appliance, considering as main outcomes the vertical dimens...
Background: This study aimed to compare the measurement agreement and intramethod reliability of four cephalometric analysis workflows: manual tracing, semi-automated digital analysis (Dolphin), fully automated AI-based analysis (WebCeph), and expert...
Background/Objectives: The literature suggests that the cranial base angle is considered one of the contributing factors to sagittal jaw malpositions when its relationship with the viscerocranium is examined. Our study aims to compare and evaluate th...
Objectives: The present study aimed to evaluate the sexual dimorphism of skeletal and dental anomalies in Romanian orthodontic patients and to describe several important cephalometric measurements in patients with dental malocclusions. Materials and ...