Changes in Maxillary Incisor Inclination Before and After Orthodontic Treatment Across Vertical Skeletal Patterns
Abstract
1. Introduction
2. Materials and Methods
- CCA-H: The angle between the clinical crown axis (CCA) and the horizontal reference line (H). The CCA is defined as the line extending from the incisal edge of the maxillary central incisor to the most prominent point on the labial surface of the crown.
- CCA–Sn-Pg′: The angle between the CCA and the line connecting subnasale (Sn) to soft tissue pogonion (Pg′). The subnasale (Sn) is the deepest point at the junction of the nose and upper lip, where the nasal septum meets the upper cutaneous lip in the midsagittal plane. Soft tissue pogonion (Pg′) is the most anterior point on the chin.
- CCA-V: The angle between the CCA and the true vertical (V). The true vertical represents the gravitational vertical.
3. Statistical Analysis
4. Results
4.1. Comparison of Cephalometric Changes Among Skeletal Divergence Groups
- Facial axis to horizontal plane (Facial axis/H) showed a significant difference between groups (p = 0.020). Post hoc comparisons indicated a significant difference between the normodivergent and hyperdivergent groups (p = 0.019), with no significant differences between the normodivergent and hypodivergent (p = 1.000) or the hypodivergent and hyperdivergent groups (p = 0.172) (Table 3).
- Mandibular plane angle relative to SN (MP/SN) also showed a significant difference among the groups (p = 0.025). The difference between hypodivergent and hyperdivergent groups was statistically significant (p = 0.021), whereas no significant differences were found between normodivergent and hypodivergent (p = 0.197) or normodivergent and hyperdivergent groups (p = 0.694) (Table 3).
4.2. Correlations Between Maxillary Incisors Inclination and the Facial and Growth Axes Before (T1) and After (T2) Orthodontic Treatment
5. Discussion
Clinical Implications, Limitations, and Future Directions
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Doshi, P.; Kalia, A.; Patil, W.; Gupta, G.; Ahmed, D.I. Evaluation of the Effect of Maxillary Incisor Labiolingual Inclination & Antero-Posterior Position on Smiling Profile Esthetics—A Computer Aided Photographic Study. Sci. J. Res. Dent. 2017, 1, 43–49. [Google Scholar]
- Cao, L.; Zhang, K.; Bai, D.; Jing, Y.; Tian, Y.; Guo, Y. Effect of maxillary incisor labiolingual inclination and anteroposterior position on smiling profile esthetics. Angle Orthod. 2011, 81, 121–129. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Richmond, S.; Klufas, M.L.; Sywanyk, M. Assessing incisor inclination: A non-invasive technique. Eur. J. Orthod. 1998, 20, 721–726. [Google Scholar] [CrossRef] [PubMed]
- Ghahferokhi, A.E.; Elias, L.; Jonsson, S.; Rolfe, B.; Richmond, S. Critical assessment of a device to measure incisor crown inclination. Am. J. Orthod. Dentofacial Orthop. 2002, 121, 185–191. [Google Scholar] [CrossRef] [PubMed]
- Knösel, M.; Kubein-Meesenburg, D.; Sadat-Khonsari, R. The third-order angle and the maxillary incisor’s inclination to the NA line. Angle Orthod. 2007, 77, 82–87. [Google Scholar] [CrossRef] [PubMed]
- Sabri, R. The eight components of a balanced smile. J. Clin. Orthod. 2005, 39, 155–167, quiz 154. [Google Scholar] [PubMed]
- Jacobson, A. Radiographic Cephalometry from Basics to 3-D Imaging, 2nd ed.; Quintessence Publishing Co., Limited: New Malden, UK, 2006. [Google Scholar]
- Ellis, E., 3rd; McNamara, J.A., Jr. Cephalometric evaluation of incisor position. Angle Orthod. 1986, 56, 324–344. [Google Scholar] [CrossRef] [PubMed]
- Naini, F.B. Facial Aesthetics: Concepts and Clinical Diagnosis; John Wiley & Sons, Ltd.: Hoboken, NJ, USA, 2011. [Google Scholar]
- Arnett, W.; McLaughlin, R. Facial and Dental Planning for Orthodontists and Oral Surgeons; Mosby: Maryland Heights, MO, USA, 2004. [Google Scholar]
- Ricketts, R.M. Cephalometric analysis and synthesis. Angle Orthod. 1961, 31, 141–156. [Google Scholar]
- Downs, W.B. Analysis of the Dentofacial Profile. Angle Orthod. 1956, 26, 191–212. [Google Scholar]
- Andrews, W.A. AP relationship of the maxillary central incisors to the forehead in adult white females. Angle Orthod. 2008, 78, 662–669. [Google Scholar] [CrossRef] [PubMed]
- Ghaleb, N.; Bouserhal, J.; Bassil-Nassif, N. Aesthetic evaluation of profile incisor inclination. Eur. J. Orthod. 2011, 33, 228–235. [Google Scholar] [CrossRef] [PubMed]
- Albwardi, M.; Albwardi, S.; Dobaian, K.; Alqahtani, K.; Altayir, A.; Almutawa, A. The Influence of Maxillary Incisor Labiolingual Inclination on Smiling Profile Esthetics Among Saudis. Cureus 2022, 14, e20966. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Proffit, W.R.; Fields, H.W.; Larson, B.E.; Sarver, D.M. Contemporary Orthodontics, 6th ed.; Elsevier: Philadelphia, PA, USA, 2019. [Google Scholar]
- Hussels, W.; Nanda, R.S. Analysis of factors affecting angle ANB. Am. J. Orthod. 1984, 85, 411–423. [Google Scholar] [CrossRef] [PubMed]
- Bishara, S.E.; Jakobsen, J.R. Changes in overbite and face height from 5 to 45 years of age in normal subjects. Angle Orthod. 1998, 68, 209–216. [Google Scholar] [CrossRef] [PubMed]
- Assi, S.B.; Salameh, Z.; Hanna, A.; Aybout, J.; Macari, A. Orthodontic Treatment Effect on Inclination of Maxillary Incisors and Growth Axes in Adult Patients with Various Mandibular Divergent Patterns. J. Contemp. Dent. Pract. 2021, 22, 1008–1013. [Google Scholar] [CrossRef] [PubMed]
- Naini, F.B.; Manouchehri, S.; Al-Bitar, Z.B.; Gill, D.S.; Garagiola, U.; Wertheim, D. The maxillary incisor labial face tangent: Clinical evaluation of maxillary incisor inclination in profile smiling view and idealized aesthetics. Maxillofac. Plast. Reconstr. Surg. 2019, 41, 31. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Cheng, H.C.; Cheng, P.C. Factors affecting smile esthetics in adults with different types of anterior overjet malocclusion. Korean J. Orthod. 2017, 47, 31–38. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Palmares, S.; Caseiro, R.; Pereira, R.; Jardim, L. Perception of maxillary incisor inclination and its correlation with dental cephalometric measurements. J. Orthod. 2024, 51, 354–365. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Flores-Mir, C.; Silva, E.; Barriga, M.I.; Lagravere, M.O.; Major, P.W. Lay person’s perception of smile aesthetics in dental and facial views. J. Orthod. 2004, 31, 204–209, discussion 201. [Google Scholar] [CrossRef] [PubMed]
- Sarver, D.M.; Ackerman, M.B. Dynamic smile visualization and quantification: Part 1. Evolution of the concept and dynamic records for smile capture. Am. J. Orthod. Dentofacial Orthop. 2003, 124, 4–12. [Google Scholar] [CrossRef] [PubMed]
- Burns, N.R.; Musich, D.R.; Martin, C.; Razmus, T.; Gunel, E.; Ngan, P. Class III camouflage treatment: What are the limits? Am. J. Orthod. Dentofacial Orthop. 2010, 137, 9.e1–9.e13, discussion 9–11. [Google Scholar] [CrossRef] [PubMed]
- Troy, B.A.; Shanker, S.; Fields, H.W.; Vig, K.; Johnston, W. Comparison of incisor inclination in patients with Class III malocclusion treated with orthognathic surgery or orthodontic camouflage. Am. J. Orthod. Dentofacial Orthop. 2009, 135, 146.e1–146.e9, discussion 146–147. [Google Scholar] [CrossRef] [PubMed]
- Kau, C.H.; Bakos, K.; Lamani, E. Quantifying changes in incisor inclination before and after orthodontic treatment in class I, II, and III malocclusions. J. World Fed. Orthod. 2020, 9, 170–174. [Google Scholar] [CrossRef] [PubMed]
- Schudy, F.F. Vertical growth versus anteroposterior growth as related to function and treatment. Angle Orthod. 1964, 34, 75–93. [Google Scholar]
- Enlow, D.H.; Hans, M.G. Essentials of Facial Growth; Saunders: Philadelphia, PA, USA, 1996. [Google Scholar]
- Zierhut, E.C.; Joondeph, D.R.; Artun, J.; Little, R.M. Long-term profile changes associated with successfully treated extraction and nonextraction Class II Division 1 malocclusions. Angle Orthod. 2000, 70, 208–219. [Google Scholar] [CrossRef] [PubMed]
- Chirivella, P.; Singaraju, G.S.; Mandava, P.; Reddy, V.K.; Neravati, J.K.; George, S.A. Comparison of the effect of labiolingual inclination and anteroposterior position of maxillary incisors on esthetic profile in three different facial patterns. J. Orthod. Sci. 2017, 6, 1–10. [Google Scholar] [CrossRef]
- Sarver, D.M. The importance of incisor positioning in the esthetic smile: The smile arc. Am. J. Orthod. Dentofacial Orthop. 2001, 120, 98–111. [Google Scholar] [CrossRef] [PubMed]
- Ackerman, M.B.; Ackerman, J.L. Smile analysis and design in the digital era. J. Clin. Orthod. 2002, 36, 221–236. [Google Scholar] [PubMed]
- Graber, T.M.; Vanarsdall, R.L.; Vig, K.W. Orthodontics: Current Principles and Techniques, 5th ed.; Elsevier: St. Louis, MO, USA, 2011. [Google Scholar]


| Groups | Mean ± SD | Mean ± SD | Mean ± SD | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Normo T1 (n = 66) 20 ♂ & 46 ♀ | Normo T2 (n = 66) 20 ♂ & 46 ♀ | p | Hypo T1 (n = 35) 17 ♂ & 18 ♀ | Hypo T2 (n = 35) 17 ♂ & 18 ♀ | p | Hyper T1 (n = 43) 11 ♂ & 32 ♀ | Hyper T2 (n = 43) 11 ♂ & 32 ♀ | p | |
| Age (year) | 26.805 ± 11.585 | 32.102 ± 24.984 | 0.065 | 26.929 ± 9.344 | 29.824 ± 9.911 | 0.000 | 28.005 ± 9.381 | 30.900 ± 9.866 | 0.000 |
| Maxillary incisors/NA | 22.086 ± 9.635 | 22.109 ± 7.690 | 0.984 | 23.994 ± 9.181 | 26.326 ± 6.857 | 0.130 | 20.063 ± 7.790 | 20.495 ± 6.650 | 0.718 |
| Maxillary incisors/PP | 112.212 ± 9.563 | 112.423 ± 7.709 | 0.839 | 113.464 ± 10.254 | 116.077 ± 7.971 | 0.145 | 109.321 ± 8.177 | 109.614 ± 7.575 | 0.804 |
| Maxillary incisors/SN | 102.935 ± 15.655 | 104.921 ± 7.184 | 0.297 | 106.966 ± 10.211 | 109.457 ± 7.617 | 0.135 | 98.640 ± 9.221 | 96.058 ± 14.929 | 0.308 |
| ANB | 3.073 ± 2.940 | 3.003 ± 3.156 | 0.765 | 2.343 ± 2.419 | 2.646 ± 4.231 | 0.671 | 4.444 ± 2.184 | 4.512 ± 2.017 | 0.676 |
| Facial axis/NBa | 90.236 ± 3.822 | 90.788 ± 3.561 | 0.058 | 93.737 ± 4.766 | 93.520 ± 4.572 | 0.636 | 84.179 ± 4.670 | 83.886 ± 4.454 | 0.488 |
| Facial axis/H | 117.092 ± 3.506 | 118.213 ± 5.873 | 0.067 | 120.328 ± 4.370 | 120.851 ± 6.375 | 0.555 | 111.358 ± 4.969 | 109.460 ± 7.647 | 0.069 |
| Growth axis/NBa | 93.454 ± 3.452 | 93.466 ± 4.105 | 0.973 | 95.085 ± 6.027 | 94.971 ± 6.081 | 0.771 | 88.253 ± 4.818 | 87.669 ± 4.439 | 0.181 |
| Growth axis/H | 120.377 ± 3.064 | 120.755 ± 3.752 | 0.251 | 122.585 ± 3.852 | 122.526 ± 4.128 | 0.873 | 115.619 ± 5.287 | 115.533 ± 5.690 | 0.822 |
| Maxillary incisors/NBa | 85.857 ± 11.856 | 86.071 ± 9.497 | 0.829 | 89.208 ± 14.383 | 91.551 ± 12.003 | 0.141 | 80.267 ± 8.900 | 80.383 ± 7.672 | 0.926 |
| Maxillary incisors/H | 112.058 ± 9.360 | 111.980 ± 7.243 | 0.939 | 114.183 ± 10.581 | 116.449 ± 7.771 | 0.177 | 107.207 ± 8.982 | 106.265 ± 7.981 | 0.478 |
| MP/SN | 32.165 ± 2.464 | 32.365 ± 3.706 | 0.609 | 23.857 ± 4.306 | 25.297 ± 5.078 | 0.011 | 41.812 ± 3.771 | 41.258 ± 4.325 | 0.276 |
| IMPA | 94.917 ± 9.420 | 94.936 ± 9.509 | 0.983 | 96.014 ± 7.711 | 98.974 ± 8.861 | 0.014 | 93.502 ± 8.124 | 95.409 ± 7.751 | 0.064 |
| Interincisal angle | 128.350 ± 13.045 | 127.211 ± 10.659 | 0.403 | 131.380 ± 13.863 | 125.503 ± 9.752 | 0.061 | 126.902 ± 13.602 | 123.674 ± 10.403 | 0.074 |
| Groups | Mean ± SD | p | Mean ± SD | p | Mean ± SD | p | |||
|---|---|---|---|---|---|---|---|---|---|
| Normo T1 (n = 66) 20 ♂ & 46 ♀ | Normo T2 (n = 66) 20 ♂ & 46 ♀ | Hypo T1 (n = 35) 17 ♂ & 18 ♀ | Hypo T2 (n = 35) 17 ♂ & 18 ♀ | Hyper T1 (n = 43) 11 ♂ & 32 ♀ | Hyper T2 (n = 43) 11 ♂ & 32 ♀ | ||||
| CCA/V | −4.74 ± 9.124 | −4.62 ± 6.841 | 0.902 | −4.83 ± 7.610 | −3.43 ± 7.397 | 0.219 | −6.35 ± 9.365 | −4.30 ± 8.484 | 0.194 |
| CCA/Sn′ | 0.45 ± 8.862 | 0.06 ± 6.704 | 0.710 | −0.69 ± 9.698 | −0.31 ± 7.936 | 0.770 | 0.88 ± 9.008 | 2.67 ± 6.802 | 0.241 |
| CCA/H | 85.05 ± 9.008 | 85.35 ± 6.813 | 0.754 | 85.34 ± 7.604 | 86.57 ± 7.397 | 0.284 | 83.60 ± 8.862 | 85 ± 8.053 | 0.383 |
| Groups | Mean ± SD | p | Σ | ||||
|---|---|---|---|---|---|---|---|
| Normo δ (n = 66) 20 ♂ & 46 ♀ | Hypo δ (n = 35) 17 ♂ & 18 ♀ | Hyper δ (n = 43) 17 ♂ & 18 ♀ | Between Normo & Hypo | Between Normo & Hyper | Between Hypo & Hyper | ||
| Age (year) | 2.459 ± 1.356 | 2.895 ± 1.923 | 2.895 ± 1.437 | 0.240 | |||
| Maxillary incisors/NA | 0.0227 ± 8.914 | 2.331 ± 8.889 | 0.432 ± 7.808 | 0.427 | |||
| Maxillary incisors/PP | 0.210 ± 8.406 | 2.431 ± 9.654 | 0.293 ± 7.687 | 0.419 | |||
| Maxillary incisors/SN | 1.986 ± 15.354 | 2.491 ± 9.633 | −2.581 ± 16.410 | 0.202 NS | |||
| ANB | −0.697 ± 1.883 | 0.302 ± 4.184 | 0.067 ± 1.049 | 0.774 | |||
| Facial axis/NBa | 0.551 ± 2.320 | −0.217 ± 2.688 | −0.293 ± 2.743 | 0.165 | |||
| Facial axis/H | 1.121 ± 4.891 | 0.522 ± 5.185 | −1.897 ± 6.671 | 0.020 | 1.000 | 0.019 | 0.172 |
| Growth axis/NBa | 0.012 ± 2.849 | −0.114 ± 2.309 | −0.583 ± 2.814 | 0.525 | |||
| Growth axis/H | 0.377 ± 2.645 | −0.060 ± 2.205 | −0.086 ± 2.493 | 0.559 | |||
| Maxillary incisors/NBa | 0.213 ± 8.006 | 2.342 ± 9.194 | 0.116 ± 8.215 | 0.413 | |||
| Maxillary incisors/H | −0.077 ± 8.223 | 2.265 ± 9.719 | −0.941 ± 8.629 | 0.255 | |||
| MP/SN | 0.200 ± 3.159 | 1.440 ± 3.155 | −0.553 ± 3.289 | 0.025 | 0.197 | 0.694 | 0.021 |
| IMPA | 0.019 ± 7.512 | 2.960 ± 7.742 | 1.906 ± 6.580 | 0.113 | |||
| Interincisal angle | −1.139 ± 10.995 | −5.877 ± 11.736 | −3.227 ± 11.536 | 0.137 | |||
| Hypodivergent n = 35 | Normodivergent n = 66 | Hyperdivergent n = 43 | |||||
|---|---|---|---|---|---|---|---|
| CCA/V | CCA/Snpg′ | CCA/V | CCA/Snpg′ | CCA/V | CCA/Snpg′ | ||
| Facial axis/NBa | T1 | 0.44 ** | 0.27 | 0.37 ** | 0.15 | 0.02 | −0.09 |
| T2 | 0.16 | −0.01 | 0.21 | −0.01 | 0.042 | −0.11 | |
| Facial axis/H | T1 | 0.44 ** | 0.13 | 0.30 * | 0.06 | −0.06 | −0.13 |
| T2 | 0.27 | 0.04 | −0.05 | −0.15 | 0.19 | 0.09 | |
| G axis/NBa | T1 | −0.23 | −0.27 | 0.25 * | 0.04 | 0.05 | −0.05 |
| T2 | −0.34 * | −0.52 ** | 0.14 | −0.09 | 0.09 | 0.45 | |
| G axis/H | T1 | 0.01 | −0.26 | 0.24 | 0.01 | −0.06 | −0.11 |
| T2 | −0.02 | −0.34 * | −0.13 | −0.27 * | −0.11 | −0.19 | |
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Bou Assi, S.; Hanna, A.E.; Khoury, R.P.; Macari, A.T. Changes in Maxillary Incisor Inclination Before and After Orthodontic Treatment Across Vertical Skeletal Patterns. Diagnostics 2025, 15, 2933. https://doi.org/10.3390/diagnostics15222933
Bou Assi S, Hanna AE, Khoury RP, Macari AT. Changes in Maxillary Incisor Inclination Before and After Orthodontic Treatment Across Vertical Skeletal Patterns. Diagnostics. 2025; 15(22):2933. https://doi.org/10.3390/diagnostics15222933
Chicago/Turabian StyleBou Assi, Samar, Antoine E. Hanna, Rita Pamela Khoury, and Anthony T. Macari. 2025. "Changes in Maxillary Incisor Inclination Before and After Orthodontic Treatment Across Vertical Skeletal Patterns" Diagnostics 15, no. 22: 2933. https://doi.org/10.3390/diagnostics15222933
APA StyleBou Assi, S., Hanna, A. E., Khoury, R. P., & Macari, A. T. (2025). Changes in Maxillary Incisor Inclination Before and After Orthodontic Treatment Across Vertical Skeletal Patterns. Diagnostics, 15(22), 2933. https://doi.org/10.3390/diagnostics15222933

