166 Results Found

An electrochemical-DNA (E-DNA) sensor was constructed by using DNA metallization to produce an electrochemical signal reporter in situ and hybridization chain reaction (HCR) as signal amplification strategy. The cyclic voltammetry (CV) technique was...

Dowex® HCR-S ion-exchange resin was used to adsorb ectoine in a batch system under varying operation conditions in terms of contact time, temperature, pH value, initial concentration of ectoine, and type of salt. Six adsorption isotherm models (Langm...

Wear of TiAlCN coatings deposited on HCR (High Contact Ratio) gears was studied by the Niemann test during which the tested gears were loaded up to the 12th load stage. The resistance against scuffing was evaluated based on the criteria of allowable...

Sea anemones are a rich source of biologically active compounds. Among approximately 1100 species described so far, Heteractis crispa species, also known as sebae anemone, is native to the Indo-Pacific area. As part of its venom components, the Hcr 1...

This paper discusses the possible early crack detectability performances of low contact ratio (LCR) and high contact ratio (HCR) spur gears. CAD models of the LCR and HCR gears are created using the rack cutter type tool. Static bending stress analys...

Abnormal expression of miRNAs is associated with the occurrence and progression of cancer and other diseases, making miRNAs essential biomarkers for disease diagnosis and prognosis. However, the intrinsic properties of miRNAs, such as short length, l...

Tooth root bending stress and surface contact stress are two major determinants of the load carrying capacity of gear drives. Generally, a high contact ratio has the potential to enhance the gear strength. In this paper, the basic procedures and meth...

Globally, the emergence of the coronavirus disease (COVID-19) has had a significant impact on life. The need for ongoing SARS-CoV-2 screening employing inexpensive and quick diagnostic approaches is undeniable, given the ongoing pandemic and variatio...

Apurinic/apyrimidinic endonuclease 1 (APE1) selectively cleaves the apurinic/apyrimidinic site (AP site) in DNA, playing a critical role in base excision repair and genomic stability maintenance. Aberrant APE1 expression has been linked to numerous d...

Angiotensin-converting enzyme 2 (ACE2) has been identified as the cellular entry receptor for the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). High ACE2 tissue expression and low glycine levels were suggested to increase suscep...

The risk of the development of tendon disorders or ruptures increases with age, but it is unclear whether intrinsic fitness during lifetime might also affect tendon properties. To investigate this, a contrasting rat model of high-capacity runners (HC...

DNA circuits have proven to be useful amplifiers for diagnostic applications, in part because of their modularity and programmability. In order to determine whether different circuits could be modularly stacked, we used a catalytic hairpin assembly (...

Biomaterial use is a promising approach to facilitate wound healing of the bone tissue. Biomaterials induce the formation of membrane capsules and the recruitment of different types of macrophages. Macrophages are immune cells that produce diverse co...

This paper presents a novel temperature compensation approach for dual-axis Micro–Electro–Mechanical System (MEMS) accelerometers, integrating Adaptive Mode Decomposition (AMD) with Grey Wolf Optimization (GWO) and Hybrid Convolutional&nd...

Butterfly larvae display intricate cognitive capacities and behaviors, but relatively little is known about how those behaviors alter their brains at the molecular level. Here, we optimized a hybridization chain reaction 3.0 (HCR v3.0) protocol to vi...

Minimal-access cardiac surgery appears to be the future. It is increasingly desired by cardiologists and demanded by patients who perceive superiority. Minimal-access coronary artery revascularisation has been increasingly adopted throughout the worl...

Background: At an international level, the risk assessment and management process of violent offenders follows a standard method that implies well-defined theoretical models and the use of scientifically validated tools. In Italy, this process is sti...

Industries demand stringent requirements towards economical machining without hindering the surface quality while cutting high carbon high chromium (HcHcr) steel. Electrical discharge machining (EDM) of HcHcr steel aims at reducing machining cost (i....

The objective of this study is to evaluate the association between the head-to-chest circumference ratio (HCR) and birth weight (BW), colostrum intake, and average daily weight gain (ADG) at preweaning and postweaning periods. Additionally, associati...

A fluorogenic aptamer (FA)-based hybridization chain reaction (HCR) could provide a sensitive and label-free signal amplification method for imaging molecules in living cells. However, existing FA-HCR methods usually face some problems, such as a com...

This paper estimated and evaluated the spatial–temporal evolution of the concentration of healthcare resources (HCRs), in 31 provinces in China between 2004 and 2017, by using the entropy method. The spatial Durbin model (SDM) was used to furth...

Even though the hydrodynamic cavitation reactor (HCR) performs better than the mechanical stirring reactor (MSR) at producing biodiesel, and the ethylic process of biodiesel production is entirely bio-based and environmentally friendly, non-homogeneo...

Currently, five peptide modulators of acid-sensing ion channels (ASICs) attributed to structural class 1b of sea anemone toxins have been described. The APETx2 toxin is the first and most potent ASIC3 inhibitor, so its homologs from sea anemones are...

Mammary tumors are the most prevalent type of tumors in female dogs. Breast cancer 2, early onset (BRCA2) malignant mutations are associated with tumorigenesis in humans and dogs. BRCA2 plays a pivotal role in homologous recombination repair by recru...

The sustainment of replication and transcription of damaged DNA is essential for cell survival under genotoxic stress; however, the damage tolerance of these key cellular functions comes at the expense of fidelity. Thus, translesion DNA synthesis (TL...

Bone is a very complex tissue that is constantly changing throughout the lifespan. The precise mechanism of bone regeneration remains poorly understood. Large bone defects can be caused by gunshot injury, trauma, accidents, congenital anomalies and t...

To ensure sustainability, the Ecosystem Approach to Fisheries (EAF) requires the evaluation of the impacts of fisheries beyond the main targeted species, to include those on bycaught, endangered, threatened and protected populations and keystone spec...

Rev7 is a regulatory protein with roles in translesion synthesis (TLS), double strand break (DSB) repair, replication fork protection, and cell cycle regulation. Rev7 forms a homodimer in vitro using its HORMA (Hop, Rev7, Mad2) domain; however, the f...

The invention of the microscope has been fundamental for the understanding of tissue architecture and subcellular structures. With the advancement of higher magnification microscopes came the development of various molecular biology tools such as För...

POU genes are a family of evolutionarily conserved transcription factors with key functions in cell type specification and neurogenesis. In vitro experiments have indicated that the expression of some POU genes is controlled by the intercellular sign...

Management Strategy Evaluation (MSE) tools are inspired by the need for transparency, efficiency, and collaboration in harvest control rule (HCR) management. MSEs provide quantified metrics of the HCR performances and indicate the goodness in multipl...

Heifer conception rate to the first service (HCR1) is defined as the number of heifers that become pregnant to the first breeding service compared to the heifers bred. This study aimed to identify loci associated and gene sets enriched for HCR1 for h...

Heifer conception rate (HCR) is defined as the percentage of inseminated heifers that become pregnant at each service. The genome-wide association analyses in this study focused on identifying the loci associated with Holstein heifer (n = 2013) conce...

Rats artificially selected over several generations for high intrinsic endurance/aerobic capacity resulting in high capacity runners (HCR) has been developed to study the links between high aerobic fitness and protection from metabolic diseases (Wisl...

Human context recognition (HCR) using sensor data is a crucial task in Context-Aware (CA) applications in domains such as healthcare and security. Supervised machine learning HCR models are trained using smartphone HCR datasets that are scripted or g...

Exercise capacity has been related to morbidity and mortality. It consists of an inherited and an acquired part and is dependent on mitochondrial function. We assessed skeletal muscle mitochondrial function in rats with divergent inherited exercise c...

In this study, polyolefin elastomer (POE) was blended with a chemically modified hydrocarbon resin (m-HCR), which was modified through a simple radical grafting reaction using γ-methacryloxypropyl trimethoxy silane (MTS) as an adhesion promotor...

Multi-hop data collection in wireless sensor networks (WSNs) is a challenge issue due to the limited energy resource and transmission range of wireless sensors. The hybrid clustering and routing (HCR) strategy has provided an effective solution, whic...

Hybrid coronary revascularisation (HCR) integrates coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) to combine the benefits of minimally invasive surgery and advanced stent technology. Typically, HCR involves off-pu...

Background: Deaths due to traffic accidents are preventable and the access to health care is an important determinant of traffic accident case fatality. This study aimed to assess the relation between mortality due to traffic accidents and health car...

The conventional hybridization chain reaction (HCR)-based electrochemical biosensors usually require the immobilization of probes on the electrode surface. This will limit the applications of biosensors due to the shortcomings of complex immobilizati...

Today, with the globalization of the food trade progressing, food safety continues to warrant widespread attention. Foodborne diseases caused by contaminated food, including foodborne pathogens, seriously threaten public health and the economy. This...

Presently, there is a paradoxical situation in the global energy market related to a gap between the image of hydrocarbon resources (HCR) and their real value for the economy. On the one hand, we face an increase in expected HCR production and consum...

Exercise in humans and animals increases plasma bilirubin levels, but the mechanism by which this occurs is unknown. In the present study, we utilized rats genetically selected for high capacity running (HCR) and low capacity running (LCR) to determi...

In the past few decades, a considerable number of old houses have been demolished in China’s urban redevelopment projects, which led to the disappearance of some historic buildings and the relocation of the original residents. Recently, the str...

Surface Plasmon Resonance (SPR) is widely used in biological and chemical sensing with fascinating properties. However, the application of SPR to detect trace targets is hampered by non-specific binding and poor signal. A variety of approaches for am...

Synthetic scaffolds with the ability to prevent fibrous tissue penetration and promote bone augmentation may realize guided bone regeneration without the use of a barrier membrane for dental implantation. Here, we fabricated two types of honeycomb sc...

The unmixing-based spatiotemporal fusion model is one of the effective ways to solve limitations in temporal and spatial resolution tradeoffs in a single satellite sensor. By using fusion data from different satellite platforms, high resolution in bo...

In the present work, the sludge treatment performance of a sludge treatment using a rotor-stator type hydrodynamic cavitation reactor (HCR) was investigated. To verify the performance, a comparison with an ultrasonic bath was conducted in four experi...

Assays for the high throughput screening of crops for virus monitoring need to be quick, easy, and low cost. One method involves using tissue blot immunoassays (TBIA), where plant stems are blotted onto nitrocellulose membrane and screened with avail...