Skip to Content
You are currently on the new version of our website. Access the old version .

6,530 Results Found

  • Article
  • Open Access
10 Citations
9,296 Views
13 Pages

Prediction of Lumbar Disc Bulging and Protrusion by Anthropometric Factors and Disc Morphology

  • Isabella Yu-Ju Hung,
  • Tiffany Ting-Fang Shih,
  • Bang-Bin Chen and
  • Yue Leon Guo

The relationship between reduced disc height and disc bulging and/or protrusion has been controversial. The purposes of this study were to examine the relationship between disc morphology and disc bulging and protrusion and to establish a model for p...

(This article belongs to the Section Public Health Statistics and Risk Assessment)
  • Article
  • Open Access
7 Citations
7,127 Views
11 Pages

12 October 2023

Purpose: The main purpose of this study was to evaluate the intervertebral disc height and intervertebral disc degeneration between the normal group and the group with disc herniation at the level of the L4–L5 intervertebral disc by MRI using t...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
10 Citations
3,512 Views
13 Pages

Smaller Intervertebral Disc Volume and More Disc Degeneration after Spinal Distraction in Scoliotic Children

  • Sebastian Lippross,
  • Paul Girmond,
  • Katja A. Lüders,
  • Friederike Austein and ,
  • Lena Braunschweig,
  • Stefan Lüders,
  • Konstantinos Tsaknakis,
  • Heiko M. Lorenz and
  • Anna K. Hell
  • + 4 authors+ 0 author

14 May 2021

In recent decades, magnetically controlled growing rods (MCGR) were established to treat progressive early-onset scoliosis. The aim of this investigation was to assess the effect of long-term MCGR with continuous distraction on intervertebral discs i...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
12 Citations
4,259 Views
11 Pages

Risk Factors for Cervical Disc Arthroplasty Subsidence with Bryan Disc—A Retrospective Observational Analysis

  • Cheng-Ying Lee,
  • Kuan-Kai Tung,
  • Hsi-Kai Tsou,
  • Wen-Hsien Chen and ,
  • Chung-Yuh Tzeng,
  • Ruei-Hong Lin,
  • Tse-Yu Chen,
  • Chih-Wei Huang and
  • Ting-Hsien Kao
  • + 4 authors+ 0 author

10 March 2024

Background: Cervical disc arthroplasty (CDA) is currently used instead of fusion to preserve cervical spine motion. Cervical implant subsidence is a potential complication after CDA. Methods: Radiological measurements were recorded via patient antero...

(This article belongs to the Section General Surgery)
  • Article
  • Open Access
14 Citations
3,779 Views
14 Pages

Nonlinear Relationship between Temporomandibular Joint Disc Displacement Distance and Disc Length: A Magnetic Resonance Imaging Analysis

  • Qinlanhui Zhang,
  • Zheng Ye,
  • Yange Wu,
  • Yufan Zhu and ,
  • Jiaqi Liu,
  • Wenke Yang,
  • Chengxinyue Ye,
  • Sophie Lau Rui Han,
  • Jun Wang and
  • Xin Xiong
  • + 5 authors+ 0 author

1 December 2022

Objective: to explore the association between the distance of disc displacement and disc morphology in patients with temporomandibular disorders (TMDs). Methods: a total of 717 joints in 473 subjects were enrolled in this cross-sectional study. The m...

(This article belongs to the Special Issue Clinical Updates in Oral Rehabilitation)
  • Review
  • Open Access
4 Citations
18,962 Views
17 Pages

Intervertebral Disc Disease in Dogs

  • Iván Gómez Álvarez,
  • José Manuel Verdes García and
  • Luciano Espino López

20 June 2025

Intervertebral disc disease is the most common disease of the spine in dogs and is a main cause of pain and neurologic dysfunction. This article reviews fundamental aspects of the pathophysiology, clinical presentation, diagnosis, and treatment of di...

  • Article
  • Open Access
3 Citations
2,506 Views
20 Pages

An Ex Vivo Intervertebral Disc Slice Culture Model for Studying Disc Degeneration and Immune Cell Interactions

  • Eunha G. Oh,
  • Li Xiao,
  • Zhiwen Xu,
  • Yuan Xing and ,
  • Yi Zhang,
  • Parastoo Anbaei,
  • Jialun A. Chi,
  • Li Jin,
  • Rebecca R. Pompano and
  • Xudong Li
  • + 5 authors+ 0 author

8 August 2025

Intervertebral disc degeneration is a leading cause of back and leg pain and a major contributor to disability worldwide. Despite its prevalence, treatments remain limited due to incomplete understanding of its pathology. In vivo models pose challeng...

(This article belongs to the Special Issue Novel Insights into Mechanism and Treatment of Degenerative Disc Disease)
  • Article
  • Open Access
7 Citations
6,565 Views
15 Pages

Development of a Machine Learning Algorithm to Correlate Lumbar Disc Height on X-rays with Disc Bulging or Herniation

  • Pao-Chun Lin,
  • Wei-Shan Chang,
  • Kai-Yuan Hsiao,
  • Hon-Man Liu and ,
  • Ben-Chang Shia,
  • Ming-Chih Chen,
  • Po-Yu Hsieh,
  • Tseng-Wei Lai,
  • Feng-Huei Lin and
  • Che-Cheng Chang
  • + 5 authors+ 0 author

Lumbar disc bulging or herniation (LDBH) is one of the major causes of spinal stenosis and related nerve compression, and its severity is the major determinant for spine surgery. MRI of the spine is the most important diagnostic tool for evaluating t...

(This article belongs to the Special Issue Artificial Intelligence in Clinical Medical Imaging)
  • Case Report
  • Open Access
9 Citations
3,364 Views
10 Pages

Metabolic Biomarkers Differentiate a Surgical Intervertebral Disc from a Nonsurgical Intervertebral Disc

  • Beata Toczylowska,
  • Michal Woznica,
  • Elzbieta Zieminska and
  • Leszek Krolicki

Background: Degeneration of the intervertebral disc (IVD) is caused by disturbances in metabolic processes, which lead to structural disorders. The aim of this report is to analyze metabolic disorders in the degeneration process by comparing control...

(This article belongs to the Collection Feature Papers in Molecular Neurobiology)
  • Review
  • Open Access
252 Citations
33,819 Views
32 Pages

With an aging population, there is a proportional increase in the prevalence of intervertebral disc diseases. Intervertebral disc diseases are the leading cause of lower back pain and disability. With a high prevalence of asymptomatic intervertebral...

(This article belongs to the Special Issue Intervertebral Disc Disease: From Pathophysiology to Novel Therapies)
  • Article
  • Open Access
4 Citations
3,304 Views
19 Pages

4 April 2022

This paper investigates the effects of disc deformation on the tilting-induced vibration of a splined spinning disc with axial-fixed boundaries.The purpose is to provide an intuitive interpretation of the vibration variance of the wet clutch system w...

(This article belongs to the Topic Processing, Analysis, Modelling and Mechanics of Materials and Structures)
  • Article
  • Open Access
1 Citations
1,165 Views
11 Pages

Impact of Intervertebral Disc Degeneration and Endplate Changes on Cefazolin Penetration into the Intervertebral Disc

  • Aleksejs Repnikovs,
  • Kalvis Briuks,
  • Artūrs Paulausks,
  • Pēteris Studers and ,
  • Konstantīns Logviss,
  • Baiba Mauriņa,
  • Dace Bandere,
  • Jānis Kurlovičs and
  • Sigita Kazūne
  • + 4 authors+ 0 author

7 November 2025

Background and Objectives: Preoperative cefazolin is the standard of care for intervertebral disc surgery as it reduces the incidence of iatrogenic spondylodiscitis. The aim of this study was to determine the impact of intervertebral disc degeneratio...

(This article belongs to the Special Issue Advances in Minimally Invasive Spine Surgery: Technology Innovations and Complications Management)
  • Article
  • Open Access
10 Citations
1,162 Views
9 Pages

Inflammaging in the Intervertebral Disc

  • Aleksandra Sadowska,
  • Oliver Nic Hausmann and
  • Karin Wuertz-Kozak

Degeneration of the intervertebral disc – triggered by ageing, mechanical stress, traumatic injury, infection, inflammation and other factors – has a significant role in the development of low back pain. Back pain not only has a high prevalence, but...

  • Article
  • Open Access
7 Citations
5,083 Views
10 Pages

26 August 2024

Background: In recent years, minimally invasive treatment options for lumbar disc herniation, such as percutaneous laser disc decompression (PLDD), have been introduced to avoid more invasive surgical methods. Combining these minimally invasive appro...

(This article belongs to the Section Clinical Neurology)
  • Review
  • Open Access
100 Citations
24,312 Views
18 Pages

21 January 2016

The intervertebral disc is a complex structure responsible for flexibility, multi-axial motion, and load transmission throughout the spine. Importantly, degeneration of the intervertebral disc is thought to be an initiating factor for back pain. Due...

(This article belongs to the Special Issue Cell Fate Decisions in Development and Disease)
  • Review
  • Open Access
36 Citations
16,127 Views
19 Pages

28 April 2015

Adults suffering from lower back pain often find the cause of pain is degenerative disc disease. While non-surgical treatment is preferred, spinal fusion and total disc replacement remain surgical options for the patient. Total disc replacement is an...

(This article belongs to the Special Issue Tribological Performance of Artificial Joints)
  • Review
  • Open Access
8 Citations
2,809 Views
47 Pages

10 November 2025

This comprehensive narrative review of bioactive plant compounds, pro-resolving anti-inflammatory lipids, and statins shows their potential in the inhibition of intervertebral disc degeneration (IVDD), pain resolution, tissue repair, and disc regener...

(This article belongs to the Special Issue Intervertebral Disc Degeneration and Regeneration: New Molecular Mechanisms and Therapeutics—Second Edition)
  • Article
  • Open Access
16 Citations
4,373 Views
17 Pages

Modeling the Depth of Surface Cracks in Brake Disc

  • Wojciech Sawczuk,
  • Mateusz Jüngst,
  • Dariusz Ulbrich and
  • Jakub Kowalczyk

12 July 2021

The article presents the state of knowledge and research in the field of surface cracks occurring in disc braking systems of rail and car vehicles. The craze formed during the operation of vehicles is particularly dangerous and leads to breaking the...

(This article belongs to the Section Advanced Materials Characterization)
  • Article
  • Open Access
2 Citations
2,697 Views
25 Pages

Redesign of a Disc-on-Disc Computer Numerical Control Tribometer for a Wide-Range and Shudder-Resistant Operation

  • Matija Hoić,
  • Mario Hrgetić,
  • Nenad Kranjčević,
  • Joško Deur and
  • Andreas Tissot

26 December 2023

The paper presents a redesign of the custom disc-on-disc-type tribometer intended for the experimental characterization of the friction and wear of automotive dry clutch friction lining. The redesign is aimed at expanding the operating range at which...

(This article belongs to the Section Vehicle Engineering)
  • Review
  • Open Access
11 Citations
5,707 Views
12 Pages

Overview on Percutaneous Therapies of Disc Diseases

  • Salvatore Masala,
  • Fabio Salimei,
  • Adriano Lacchè,
  • Stefano Marcia and
  • Francesco Massari

12 August 2019

Low back pain is an extremely common pathology affecting a great share of the population, in particular, young adults. Many structures can be responsible for pain such as intervertebral discs, facet joints, nerve roots, and sacroiliac joints. This re...

  • Article
  • Open Access
4 Citations
2,404 Views
17 Pages

Long-Term Clinical Efficacy of the Disc-FX Procedure in Contained Disc Herniation: A 7-Year Follow-Up from a Single-Center Cohort Study

  • Magdalena Rybaczek,
  • Kacper Prokop,
  • Karol Sawicki,
  • Robert Rutkowski and ,
  • Aleksander Lebejko,
  • Grzegorz Perestret,
  • Zenon Mariak,
  • Paweł Grabala and
  • Tomasz Łysoń
  • + 4 authors+ 0 author

10 September 2025

Background: Contained lumbar disc herniation is a prevalent cause of chronic low back pain and functional impairment. The Disc-FX system, a minimally invasive, percutaneous technique integrating nucleotomy, nucleus ablation, and annuloplasty, offers...

(This article belongs to the Section Orthopedics)
  • Review
  • Open Access
577 Views
18 Pages

Diagnostic Role of Multimodal Imaging in Optic Disc Diseases

  • Claudia Fossataro,
  • Maria Cristina Savastano,
  • Francesco Mottola,
  • Francesco De Dominicis and ,
  • Giorgia Campaniello,
  • Martina Cocuzza,
  • Clara Rizzo,
  • Filippo Amore,
  • Tommaso Salgarello and
  • Stanislao Rizzo
  • + 6 authors+ 1 author

16 August 2026

The aim of this narrative review was to provide a disease-oriented diagnostic framework for selecting and integrating multimodal imaging techniques according to the suspected optic disc disorder. A non-systematic PubMed search was performed to identi...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Feature Paper
  • Review
  • Open Access
15 Citations
6,830 Views
15 Pages

Advances in Tissue Engineering for Disc Repair

  • Chang Kyu Lee,
  • Dong Hwa Heo,
  • Hungtae Chung,
  • Eun Ji Roh and ,
  • Anjani Darai,
  • Jae Won Kyung,
  • Hyemin Choi,
  • Su Yeon Kwon,
  • Basanta Bhujel and
  • Inbo Han
  • + 5 authors+ 0 author

22 February 2021

Intervertebral disc (IVD) degeneration is a leading cause of chronic low back pain (LBP) that results in serious disability and significant economic burden. IVD degeneration alters the disc structure and spine biomechanics, resulting in subsequent st...

(This article belongs to the Special Issue Intervertebral Disc Regeneration)
  • Article
  • Open Access
2 Citations
3,225 Views
9 Pages

Characteristics and Short-Term Surgical Outcomes of Patients with Recurrent Lumbar Disc Herniation after Percutaneous Laser Disc Decompression

  • Hidetomi Terai,
  • Koji Tamai,
  • Masayoshi Iwamae,
  • Kunikazu Kaneda and ,
  • Hiroshi Katsuda,
  • Nagakazu Shimada and
  • Hiroaki Nakamura
  • + 2 authors+ 0 author

10 November 2021

Background and Objectives: Although percutaneous laser disc decompression (PLDD) is one of the common treatment methods for patients with lumbar disc herniation (LDH), the recurrence of LDH after PLDD is estimated at 4–5%. This study compares the pre...

(This article belongs to the Special Issue Lumbar Spinal Stenosis: Diagnosis and Treatment Options)
  • Article
  • Open Access
9 Citations
4,475 Views
10 Pages

Full-Endoscopic Lumbar Interbody Fusion for Treating Lumbar Disc Degeneration Involving Disc Height Loss: Technical Report

  • Tsuyoshi Harakuni,
  • Hiroki Iwai,
  • Yasushi Oshima,
  • Hirokazu Inoue and ,
  • Tomoaki Kitagawa,
  • Hirohiko Inanami and
  • Hisashi Koga
  • + 2 authors+ 0 author

17 September 2020

Background and Objectives: Lumbar disc degeneration (LDD) is the main cause of lower back pain and leads to corresponding disc height loss. Although lumbar interbody fusion (LIF) is commonly used for treating LDD, several different treatment strategi...

(This article belongs to the Special Issue Complex and Minimally Invasive Spine Surgery)
  • Article
  • Open Access
6 Citations
5,039 Views
12 Pages

Association between Occupation and Cervical Disc Degeneration in 1211 Asymptomatic Subjects

  • Masaaki Machino,
  • Hiroaki Nakashima,
  • Keigo Ito,
  • Kei Ando and ,
  • Sadayuki Ito,
  • Fumihiko Kato and
  • Shiro Imagama
  • + 2 authors+ 0 author

9 June 2022

Magnetic resonance imaging (MRI) system has frequently observed degenerative changes in the cervical discs of healthy subjects. Although there are concerns regarding the link between an individual’s occupation and intervertebral disc degenerati...

(This article belongs to the Section Orthopedics)
  • Review
  • Open Access
54 Citations
9,205 Views
26 Pages

9 February 2022

Intervertebral disc (IVD) degeneration is a common cause of low back pain and most spinal disorders. As IVD degeneration is a major obstacle to the healthy life of so many individuals, it is a major issue that needs to be overcome. Currently, there i...

  • Review
  • Open Access
171 Citations
17,237 Views
19 Pages

29 August 2021

Intervertebral disc degeneration (IVDD) occurs as a result of an imbalance of the anabolic and catabolic processes in the intervertebral disc, leading to an alteration in the composition of the extracellular matrix (ECM), loss of nucleus pulposus (NP...

(This article belongs to the Collection Stem Cells in Tissue Engineering and Regeneration)
  • Review
  • Open Access
18 Citations
5,743 Views
24 Pages

The Evolution of Brake Disc Materials for Trains: A Review

  • Yelong Xiao,
  • Leliang Zhou,
  • Huoping Zhao,
  • Tianyong Wang and ,
  • Junhua Du and
  • Mingxue Shen
  • + 1 author+ 0 author

As a key component of the train braking system, the comprehensive performance of brake discs plays a vital role in ensuring the operational safety of trains. With the advent of high-speed and heavy-haul trains, the thermal energy generated by braking...

(This article belongs to the Special Issue Advancements in Surface Engineering, Coatings and Tribology)
  • Review
  • Open Access
41 Citations
8,419 Views
17 Pages

Biological Treatments for Temporomandibular Joint Disc Disorders: Strategies in Tissue Engineering

  • Daniela Trindade,
  • Rachel Cordeiro,
  • Henrique Cardoso José,
  • David Faustino Ângelo and ,
  • Nuno Alves and
  • Carla Moura
  • + 1 author+ 0 author

23 June 2021

The temporomandibular joint (TMJ) is an important structure for the masticatory system and the pathologies associated with it affect a large part of the population and impair people’s lifestyle. It comprises an articular disc, that presents low regen...

  • Review
  • Open Access
52 Citations
10,252 Views
30 Pages

The Role of Z-disc Proteins in Myopathy and Cardiomyopathy

  • Kirsty Wadmore,
  • Amar J. Azad and
  • Katja Gehmlich

The Z-disc acts as a protein-rich structure to tether thin filament in the contractile units, the sarcomeres, of striated muscle cells. Proteins found in the Z-disc are integral for maintaining the architecture of the sarcomere. They also enable it t...

(This article belongs to the Special Issue Molecular Research on Muscle Protein and Myopathies)
  • Article
  • Open Access
28 Citations
6,606 Views
19 Pages

Comparative Study on the Friction Behaviour and the Particle Formation Process between a Laser Cladded Brake Disc and a Conventional Grey Cast Iron Disc

  • Christopher Hamatschek,
  • Klaus Augsburg,
  • David Schobel,
  • Sebastian Gramstat and ,
  • Anton Stich,
  • Florian Gulden and
  • David Hesse
  • + 2 authors+ 0 author

1 February 2023

Brake-wear particle emissions are the result of the components of a friction brake being in tribological contact, and they are classified as non-exhaust emissions. Since most of the emitted particles belong to the size classes of particulate matter (...

(This article belongs to the Special Issue New Developments in Friction Brake Materials)
  • Proceeding Paper
  • Open Access
2 Citations
1,305 Views
12 Pages

Effect of Temperature Variations on Brake Squeal Characteristics in Disc Brake Systems

  • Akif Yavuz,
  • Osman Taha Sen,
  • Mustafa Enes Kırmacı and
  • Tolga Gündoğdu

13 January 2026

Brake squeal is an undesirable high-frequency noise caused by vibrations induced by friction in disc brake systems. The noise is strongly affected by temperature, as this influences the material properties of the friction pair and the dynamic behavio...

(This article belongs to the Proceedings of The 17th International Scientific Conference on Aerospace, Automotive, and Railway Engineering)
  • Article
  • Open Access
11 Citations
4,385 Views
11 Pages

17 June 2021

To analyze the effect of a groove cross-sectional shape on disc filters, a head loss analysis and filtration performance test were conducted using disc filters with different groove shapes (semi-elliptical- and trapezoidal-shaped grooves). Furthermor...

  • Article
  • Open Access
2 Citations
701 Views
14 Pages

Degree of Inflammation in Surgically Obtained Intervertebral Disc Extrusions in a Population of 74 Dogs

  • Iván Gómez Álvarez,
  • José Manuel Verdes García and
  • Luciano Espino López

16 June 2026

Intervertebral disc disease remains the most common spinal pathology in dogs and is characterized by degeneration of the intervertebral disc, primarily through chondroid metaplasia of the nucleus pulposus. Current histological grading systems for dis...

(This article belongs to the Topic Research Advances in Animal Pathophysiology)
  • Article
  • Open Access
2 Citations
4,476 Views
13 Pages

Histological and Immunohistochemical Insights into Disc Perforation in the Temporomandibular Joint: A Case Report

  • Josè Freni,
  • Antonio Centofanti,
  • Fabiana Nicita,
  • Davide Labellarte and ,
  • Giovanna Vermiglio and
  • Michele Runci Anastasi
  • + 1 author+ 0 author

Background/Objectives: Anterior disc displacement without reduction (ADDwoR) is a temporomandibular joint (TMJ) disorder characterized by progressive dysfunction and potential complications. Persistent displacement leads to abnormal mechanical stress...

(This article belongs to the Section Functional Anatomy and Musculoskeletal System)
  • Article
  • Open Access
2,329 Views
19 Pages

Improved Fixture Layout for a Floating Brake Disc

  • Mîndru Tedor Daniel,
  • Ciofu Ciprian Dumitru,
  • Grigorean Ştefan,
  • Marica Mariana and ,
  • Ilie Dumitru,
  • Tiberiu Mîrze and
  • Nedelcu Dumitru
  • + 2 authors+ 0 author

29 December 2025

The design and construction of a racing car often involve determining the optimal technological solution and designing the subassemblies, taking into account the required specifications. The case presented in this paper details improvements to the fi...

(This article belongs to the Special Issue Advances in Dynamics and Control of Vehicles)
  • Article
  • Open Access
24 Citations
14,013 Views
25 Pages

24 December 2018

Tesla turbines are a kind of unconventional bladeless turbines, which utilize the viscosity of working fluid to rotate the rotor and realize energy conversion. They offer an attractive substitution for small and micro conventional bladed turbines due...

(This article belongs to the Special Issue Engineering Fluid Dynamics 2018)
  • Article
  • Open Access
8 Citations
4,318 Views
16 Pages

A Dynamic Analysis of the Cycloid Disc Stress-Strain State

  • Milos Matejic,
  • Mirko Blagojevic,
  • Aleksandar Disic,
  • Marija Matejic and ,
  • Vladimir Milovanovic and
  • Ivan Miletic
  • + 1 author+ 0 author

30 March 2023

The problem of internal forces that occur on the cycloid disc during the cycloid speed reducer operation so far has not been considered in a way that reflects its actual workloads and stresses in the cycloid disc itself. This paper presents a dynamic...

(This article belongs to the Special Issue Modern Research of Gears and Power Transmission)
  • Review
  • Open Access
22 Citations
8,232 Views
31 Pages

Animal Models of Intervertebral Disc Diseases: Advantages, Limitations, and Future Directions

  • Jin Young Hong,
  • Hyunseong Kim,
  • Wan-Jin Jeon,
  • Changhwan Yeo and ,
  • Hyun Kim,
  • Junseon Lee,
  • Yoon Jae Lee and
  • In-Hyuk Ha
  • + 3 authors+ 0 author

9 December 2024

Animal models are valuable tools for studying the underlying mechanisms of and potential treatments for intervertebral disc diseases. In this review, we discuss the advantages and limitations of animal models of disc diseases, focusing on lumbar spin...

  • Article
  • Open Access
7 Citations
9,019 Views
13 Pages

Outcomes in Dogs with Multiple Sites of Cervical Intervertebral Disc Disease Treated with Single Ventral Slot Decompression

  • Ya-Pei Chang,
  • Wei-Hsiang Huang,
  • Wan-Zhen Lua,
  • Wenyi Wong and ,
  • I-Hsuan Liu and
  • Chen-Hsuan Liu
  • + 1 author+ 0 author

In dogs with acute myelopathy but showing multiple sites of spinal compression from intervertebral disc disease (IVDD) on imaging, one approach is surgical decompression of the single acute disc extrusion while ignoring other previously extruded or p...

(This article belongs to the Special Issue Neurology and Neurosurgery in Small Animals)
  • Article
  • Open Access
14 Citations
4,124 Views
20 Pages

Frictional Heating during Braking of the C/C Composite Disc

  • Aleksander Yevtushenko,
  • Michal Kuciej and
  • Katarzyna Topczewska

12 June 2020

An analytical model to determine temperature in a single brake disc of multi-disc system is proposed. The model considers the convective cooling on the lateral surfaces of the disc and structure of composite friction material. Calculations were carri...

(This article belongs to the Special Issue Friction and Wear of Engineering Materials )
  • Article
  • Open Access
44 Citations
11,805 Views
31 Pages

A Histopathological Scheme for the Quantitative Scoring of Intervertebral Disc Degeneration and the Therapeutic Utility of Adult Mesenchymal Stem Cells for Intervertebral Disc Regeneration

  • Cindy C. Shu,
  • Margaret M. Smith,
  • Susan M. Smith,
  • Andrew J. Dart and ,
  • Christopher B. Little and
  • James Melrose
  • + 1 author+ 0 author

The purpose of this study was to develop a quantitative histopathological scoring scheme to evaluate disc degeneration and regeneration using an ovine annular lesion model of experimental disc degeneration. Toluidine blue and Haematoxylin and Eosin (...

(This article belongs to the Special Issue Advances in Bone and Cartilage Research)
  • Article
  • Open Access
3 Citations
6,236 Views
13 Pages

An Integrated Approach for Designing and Analyzing Lumbar Vertebral Biomodels with Artificial Disc Replacement

  • Mhd Ayham Darwich,
  • Katreen Ebrahem,
  • Maysaa Shash,
  • Hasan Mhd Nazha and ,
  • Szabolcs Szávai,
  • Yicha Zhang and
  • Daniel Juhre
  • + 2 authors+ 0 author

8 December 2023

This study aims to develop an integrated approach for 3D lumbar vertebral biomodel design and analysis, specifically targeting unilevel disc degeneration and the replacement of lumbar artificial discs. Key objectives include improving existing design...

  • Article
  • Open Access
4 Citations
9,016 Views
10 Pages

Lumbar Disc Degeneration Is Linked to Dorsal Subcutaneous Fat Thickness at the L1–L2 Intervertebral Disc Level Measured by MRI

  • Ibrahem Hussain Kanbayti,
  • Abdulrahman S. Al-Buqami,
  • Mohammad H. Alsheikh,
  • Saad M. Al-Malki and ,
  • Ibrahim Hadadi,
  • Adnan Alahmadi,
  • Bander S. Almutairi and
  • Hamzah H. Ahmed
  • + 3 authors+ 0 author

17 January 2024

Background: Obese individuals have a higher risk of degenerative disc disease (DDD). Currently, body mass index is not sensitive enough to differentiate between muscle and fat distribution, and obesity-related health issues are linked to the way body...

  • Review
  • Open Access
67 Citations
14,025 Views
15 Pages

Intervertebral Disc Nucleus Repair: Hype or Hope?

  • Gauri Tendulkar,
  • Tao Chen,
  • Sabrina Ehnert,
  • Hans-Peter Kaps and
  • Andreas K Nüssler

Chronic back pain is a common disability, which is often accredited to intervertebral disc degeneration. Gold standard interventions such as spinal fusion, which are mainly designed to mechanically seal the defect, frequently fail to restore the nati...

(This article belongs to the Special Issue Molecular and Tissue Engineering Approaches in Musculoskeletal Regenerative Medicine)
  • Article
  • Open Access
902 Views
12 Pages

The degradation of intervertebral disc proteoglycans, including the loss or shortening of their hydrophilic glycosaminoglycan chains, causes a loss of disc hydration, leading to an increase in solid matrix stresses. This illustrates one aspect of the...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
13 Citations
3,049 Views
17 Pages

Insulator Umbrella Disc Shedding Detection in Foggy Weather

  • Rui Xin,
  • Xi Chen,
  • Junying Wu,
  • Ke Yang and ,
  • Xinying Wang and
  • Yongjie Zhai
  • + 1 author+ 0 author

28 June 2022

The detection of insulator umbrella disc shedding is very important to the stable operation of a transmission line. In order to accomplish the accurate detection of the insulator umbrella disc shedding in foggy weather, a two-stage detection model co...

(This article belongs to the Special Issue Deep Power Vision Technology and Intelligent Vision Sensors)
  • Article
  • Open Access
668 Views
15 Pages

The Phaistos Disc is an undeciphered Minoan-era artifact bearing 242 stamped occurrences of 45 distinct signs. We test whether it encodes one or more protein sequences, with each sign representing an amino acid or post-translationally modified amino...

  • Article
  • Open Access
6 Citations
2,922 Views
17 Pages

Accurate Intervertebral Disc Segmentation Approach Based on Deep Learning

  • Yu-Kai Cheng,
  • Chih-Lung Lin,
  • Yi-Chi Huang,
  • Guo-Shiang Lin and ,
  • Zhen-You Lian and
  • Cheng-Hung Chuang
  • + 1 author+ 0 author

Automatically segmenting specific tissues or structures from medical images is a straightforward task for deep learning models. However, identifying a few specific objects from a group of similar targets can be a challenging task. This study focuses...

(This article belongs to the Special Issue Recent Advances in Artificial Intelligence-Based Medical Image Analysis)

of 131