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5 March 2025
Journal of Clinical Medicine | Recommended Articles with Video Abstracts


Journal of Clinical Medicine (JCM, ISSN: 2077-0383) is an open access journal and has an updated 2023 Impact Factor of 3.0 and is ranked 59/329 (Q1) in the of “Medicine, General & Internal” category. All of its publications are freely available for reading and downloading and are devoted to the dissemination of important medical knowledge. In order to offer scholars more opportunities to present their research, we support the use of graphical and video abstracts. Video abstracts offer a dynamic and engaging way to present the content of submissions. They can provide a more in-depth and accessible explanation of research, increasing its reach for a wider audience.

Here are the requirements for video abstracts: (1): File formats: mp4, webm, ogv (mp4 format is usually recommended); (2): File size: no more than 200 MB; (3) Video length: no more than 5 minutes.

Video abstracts not only contribute to increasing the visibility of papers but also enhance the overall impact of research. We look forward to reading submitted papers with video abstracts.

1. “Topical Treatment Is Effective and Safe for Acute Ankle Sprains: The Multi-Center Double-Blind Randomized Placebo-Controlled TRAUMED Trial”
by Ludger Gerdesmeyer, Johannes Vester, Christian Schneider, Britt Wildemann, Christine Frank, Myron Schultz, Bernd Seilheimer, Alta Smit and Gino Kerkhoffs
J. Clin. Med. 2024, 13(3), 841; https://doi.org/10.3390/jcm13030841
Full text available online: https://www.mdpi.com/2077-0383/13/3/841

2. “Sub-Tenon’s Block in Patients with Previous Encircling Band Surgery—A Feasibility Study”
by Johannes Harte, Gesar Ugen, Joana Berger-Estilita, Andreas Ebneter and Friedrich Lersch
J. Clin. Med. 2024, 13(24), 7735; https://doi.org/10.3390/jcm13247735
Full text available online: https://www.mdpi.com/2077-0383/13/24/7735

3. “Systematic Review of Executive Function Stimulation Methods in the ADHD Population”
by Carlos Ramos-Galarza, Deyaneira Brito, Brayan Rodríguez, Brenda Guerrero, Jorge Cruz-Cárdenas and Mónica Bolaños-Pasquel
J. Clin. Med. 2024, 13(14), 4208; https://doi.org/10.3390/jcm13144208
Full text available online: https://www.mdpi.com/2077-0383/13/14/4208

4. “The Utility of Three-Dimensional Printing in Physician-Modified Stent Grafts for Aortic Lesions Repair”
by Wiktoria Antonina Zasada, Hubert Stępak, Magdalena Węglewska, Łukasz Świątek, Jerzy Kluba and Zbigniew Krasiński
J. Clin. Med. 2024, 13(10), 2977; https://doi.org/10.3390/jcm13102977
Full text available online: https://www.mdpi.com/2077-0383/13/10/2977

5. “Topographic Keratoconus Incidence in Greece Diagnosed in Routine Consecutive Cataract Procedures: A Consecutive Case Series of 1250 Cases over 5 Years”
by Anastasios John Kanellopoulos and Alexander J. Kanellopoulos
J. Clin. Med. 2024, 13(8), 2378; https://doi.org/10.3390/jcm13082378
Full text available online: https://www.mdpi.com/2077-0383/13/8/2378

6. “Fibrosis in Chronic Kidney Disease: Pathophysiology and Therapeutic Targets”
by Allison B. Reiss, Berlin Jacob, Aarij Zubair, Ankita Srivastava, Maryann Johnson and Joshua De Leon
J. Clin. Med. 2024, 13(7), 1881; https://doi.org/10.3390/jcm13071881
Full text available online: https://www.mdpi.com/2077-0383/13/7/1881

7. “The Presence of Myosteatosis Is Associated with Age, Severity of Liver Disease and Poor Outcome and May Represent a Prodromal Phase of Sarcopenia in Patients with Liver Cirrhosis”
by Eleni Geladari, Theodoros Alexopoulos, Meropi D. Kontogianni, Larisa Vasilieva, Iliana Mani, Roxane Tenta, Vasilios Sevastianos, Ioannis Vlachogiannakos and Alexandra Alexopoulou
J. Clin. Med. 2023, 12(9), 3332; https://doi.org/10.3390/jcm12093332
Full text available online: https://www.mdpi.com/2077-0383/12/9/3332

8. “Validation of an Automated Artificial Intelligence Algorithm for the Quantification of Major OCT Parameters in Diabetic Macular Edema”
by Edoardo Midena, Lisa Toto, Luisa Frizziero, Giuseppe Covello, Tommaso Torresin, Giulia Midena, Luca Danieli, Elisabetta Pilotto, Michele Figus, Cesare Mariotti and Marco Lupidi
J. Clin. Med. 2023, 12(6), 2134; https://doi.org/10.3390/jcm12062134
Full text available online: https://www.mdpi.com/2077-0383/12/6/2134

9. “Gender-Related Outcomes after Surgical Resection and Level of Satisfaction in Patients with Left Atrial Tumors”
by Viyan Sido, Annika Volkwein, Martin Hartrumpf, Christian Braun, Ralf-Uwe Kühnel, Roya Ostovar, Filip Schröter, Sofia Chopsonidou and Johannes Maximilian Albes
J. Clin. Med. 2023, 12(5), 2075; https://doi.org/10.3390/jcm12052075
Full text available online: https://www.mdpi.com/2077-0383/12/5/2075

3 March 2025
Journal of Clinical Medicine Webinar | Interaction Between Systemic Diseases and Oral Diseases, 25 March 2025


Many systemic diseases may affect oral health. This may be a manifestation of the systemic disease itself or an indirect effect due to medical treatment of this disease. Conversely, oral health can also affect the functioning of other parts of the human body. Although many such interactions between systemic diseases and oral diseases have been described in the scientific literature, the causal relationship still often remains unclear. Therefore, in this webinar, international experts will discuss some examples of interactions between systemic diseases and oral health in depth in order to gain more insight into these interactions.

Date: 25 March 2025

Time: 3:00 p.m. CET | 10:00 a.m. EDT

Webinar ID: 810 2190 0155

Webinar Secretariat:journal.webinar@mdpi.com

Webinar announcement: https://sciforum.net/event/JCM-14

Register now for free!

Speaker/Presentation

Time in CET

Time in EST

Dr. Henk S. Brand

Chair Introduction

3:00–3:10 p.m.

10:00–10:10 a.m.

Prof. Dr. Petra Surlin

Periodontitis and gastrointestinal cancers

3:10–3:30 p.m.

10:10–10:30 a.m.

Prof. Dr. Frank A. Scannapieco

Progress in the understanding of oral–lung disease associations

3:30–3:50 p.m.

10:30–10:50 a.m.

Prof. Dr. Andreea Cristiana Didilescu

Oral health of liver-transplant recipients

3:50–4:10 p.m.

10:50–11:10 a.m.

Q&A Session

4:10–4:25 p.m.

10:10–10:25 a.m.

Dr. Henk S. Brand

Closing of Webinar

4:25–4:30 p.m.

10:25–10:30 a.m.

After registering, you will receive a confirmation email containing information on how to join the webinar. Registrations with academic or institutional email addresses will be prioritized. 

Unable to attend? Feel free to still register and we will inform you when the recording is available.

Webinar Chair and Keynote Speakers:

  • Dr. Henk S. Brand, Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, the Netherlands;
  • Prof. Dr. Petra Șurlin, Department of Periodontology, Faculty of Dental Medicine, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania;
  • Prof. Dr. Frank A. Scannapieco, Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, NY 14214, USA;
  • Prof. Dr. Andreea Cristiana Didilescu, Department of Embryology and Microbiology, Faculty of Dentistry, The “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Relevant Special Issue:

Interaction Between Systemic Diseases and Oral Diseases

Guest Editor: Dr. Henk S. Brand

Deadline for manuscript submission: 31 March 2025

28 February 2025
Journal of Clinical Medicine | Highly Cited Papers in 2023—Part I


Journal of Clinical Medicine (JCM, ISSN: 2077-0383) is an open access journal with an updated CiteScore (2023) of 5.7, ranked 80/636 (Q1) in the “General Medicine” category. This is a direct result of the numerous high-quality, highly cited papers that have graced their pages. These papers not only showcase cutting-edge research in clinical medicine but also contribute significantly to the journal. A huge thank you to all the authors for their invaluable contributions. We invite you to enjoy and review part I of these papers together, hoping to bring different inspirations.

1. “2023 Update on Sepsis and Septic Shock in Adult Patients: Management in the Emergency Department”
by Matteo Guarino, Benedetta Perna, Alice Eleonora Cesaro, Martina Maritati, Michele Domenico Spampinato, Carlo Contini and Roberto De Giorgio
J. Clin. Med. 2023, 12(9), 3188; https://doi.org/10.3390/jcm12093188
Full text available online: https://www.mdpi.com/2077-0383/12/9/3188

2. “Polycystic Ovary Syndrome: Etiology, Current Management, and Future Therapeutics”
by Samradhi Singh, Namrata Pal, Swasti Shubham, Devojit Kumar Sarma, Vinod Verma, Francesco Marotta and Manoj Kumar
J. Clin. Med. 2023, 12(4), 1454; https://doi.org/10.3390/jcm12041454
Full text available online: https://www.mdpi.com/2077-0383/12/4/1454

3. “Noise-Induced Hearing Loss”
by Nirvikalpa Natarajan, Shelley Batts and Konstantina M. Stankovic
J. Clin. Med. 2023, 12(6), 2347; https://doi.org/10.3390/jcm12062347
Full text available online: https://www.mdpi.com/2077-0383/12/6/2347

4. “Chronic Low Back Pain: A Narrative Review of Recent International Guidelines for Diagnosis and Conservative Treatment”
by Vanina Nicol, Claire Verdaguer, Camille Daste, Hélène Bisseriex, Éric Lapeyre, Marie-Martine Lefèvre-Colau, François Rannou, Alexandra Rören, Julia Facione and Christelle Nguyen
J. Clin. Med. 2023, 12(4), 1685; https://doi.org/10.3390/jcm12041685
Full text available online: https://www.mdpi.com/2077-0383/12/4/1685

5. “Systemic Immune Inflammation Index (SII), System Inflammation Response Index (SIRI) and Risk of All-Cause Mortality and Cardiovascular Mortality: A 20-Year Follow-Up Cohort Study of 42,875 US Adults”
by Yiyuan Xia, Chunlei Xia, Lida Wu, Zheng Li, Hui Li and Junxia Zhang
J. Clin. Med. 2023, 12(3), 1128; https://doi.org/10.3390/jcm12031128
Full text available online: https://www.mdpi.com/2077-0383/12/3/1128

6. “Advances in Therapies to Treat Neonatal Hypoxic-Ischemic Encephalopathy”
by Amaresh K. Ranjan and Anil Gulati
J. Clin. Med. 2023, 12(20), 6653; https://doi.org/10.3390/jcm12206653
Full text available online: https://www.mdpi.com/2077-0383/12/20/6653

7. “Current Treatment Landscape for Early Triple-Negative Breast Cancer (TNBC)”
by Jieun Lee
J. Clin. Med. 2023, 12(4), 1524; https://doi.org/10.3390/jcm12041524
Full text available online: https://www.mdpi.com/2077-0383/12/4/1524

8. “Past, Present and (Foreseeable) Future of Biological Anti-TNF Alpha Therapy”
by Gian Marco Leone, Katia Mangano, Maria Cristina Petralia, Ferdinando Nicoletti and Paolo Fagone
J. Clin. Med. 2023, 12(4), 1630; https://doi.org/10.3390/jcm12041630
Full text available online: https://www.mdpi.com/2077-0383/12/4/1630

9. “Stage IV Colorectal Cancer Management and Treatment”
by Oscar Hernandez Dominguez, Sumeyye Yilmaz and Scott R. Steele
J. Clin. Med. 2023, 12(5), 2072; https://doi.org/10.3390/jcm12052072
Full text available online: https://www.mdpi.com/2077-0383/12/5/2072

10. “Recurrent Pregnancy Loss Etiology, Risk Factors, Diagnosis, and Management. Fresh Look into a Full Box”
by Akbayan Turesheva, Gulzhanat Aimagambetova, Talshyn Ukybassova, Aizada Marat, Perizat Kanabekova, Lyazzat Kaldygulova, Ainur Amanzholkyzy, Svetlana Ryzhkova, Anastassiya Nogay, Zaituna Khamidullina et al.
J. Clin. Med. 2023, 12(12), 4074; https://doi.org/10.3390/jcm12124074
Full text available online: https://www.mdpi.com/2077-0383/12/12/4074

11. “Irritable Bowel Syndrome and the Gut Microbiome: A Comprehensive Review”
by Sofia D. Shaikh, Natalie Sun, Andrew Canakis, William Y. Park and Horst Christian Weber
J. Clin. Med. 2023, 12(7), 2558; https://doi.org/10.3390/jcm12072558
Full text available online: https://www.mdpi.com/2077-0383/12/7/2558

12. “The Global Burden of Valvular Heart Disease: From Clinical Epidemiology to Management”
by Gloria Santangelo, Francesca Bursi, Andrea Faggiano, Silvia Moscardelli, Pasquale Simone Simeoli, Marco Guazzi, Roberto Lorusso, Stefano Carugo and Pompilio Faggiano
J. Clin. Med. 2023, 12(6), 2178; https://doi.org/10.3390/jcm12062178
Full text available online: https://www.mdpi.com/2077-0383/12/6/2178

27 February 2025
More than 300 MDPI Journals Indexed in Web of Science

MDPI is pleased to share a significant milestone in its mission to advance scholarly research and promote the dissemination of knowledge—300+ MDPI journals are now indexed in Web of Science (WoS). This milestone highlights the global recognition, interdisciplinary impact and enhanced visibility of our journals. It also reflects our adherence to rigorous editorial standards, scientific integrity, and our mission to foster open scientific exchange in all forms, across all disciplines. 

To explore the full list of our journals indexed in WoS, please visit https://www.mdpi.com/about/journals/wos. Beyond expanding the coverage of our publications in the leading academic databases, we are dedicated to ensuring that our journals are included in as many scope-specific databases as possible. This increases the visibility of our authors’ work and extends the reach of their significant data. 

This milestone would not have been possible without the efforts and expertise of our academic editors, reviewers and authors. Their commitment and collaboration have been instrumental in creating an inclusive, accessible, and impactful publishing platform. We also extend our gratitude to the global research community for their trust as we continue to break new ground in academic publishing. This milestone is not just a celebration of MDPI’s progress but also recognition of the collective strides made by researchers worldwide. 

As we celebrate this remarkable accomplishment, MDPI remains steadfast in its commitment to open access publishing and ensuring that high-quality research reaches and inspires a global audience.

24 February 2025
Journal of Clinical Medicine | Highly Cited Papers and Hot Topic Special Issues on Epilepsy


Epilepsy is a chronic brain disorder that cannot be ignored and affects many patients. Its causative factors are complex, and clinicians and scientists are constantly updating their research on the condition. Journal of Clinical Medicine (JCM, ISSN: 2077-0383) has collected open academic research on epilepsy. Some relevant Special Issues are currently open for the submissions; we encourage you to read these highly popular works in depth. Please click the links below to learn more about these papers:

1. “Epilepsy in Dravet Syndrome—Current and Future Therapeutic Opportunities”
by Chao Gao, Mikolaj Pielas, Fuyong Jiao, Daoqi Mei, Xiaona Wang, Katarzyna Kotulska and Sergiusz Jozwiak
J. Clin. Med. 2023, 12(7), 2532; https://doi.org/10.3390/jcm12072532
Full text available online: https://www.mdpi.com/2077-0383/12/7/2532

2. “Glycaemic Imbalances in Seizures and Epilepsy of Paediatric Age: A Literature Review”
by Emanuele Bartolini, Anna Rita Ferrari, Simona Fiori and Stefania Della Vecchia
J. Clin. Med. 2023, 12(7), 2580; https://doi.org/10.3390/jcm12072580
Full text available online: https://www.mdpi.com/2077-0383/12/7/2580

3. “Characteristics and Challenges of Epilepsy in Children with Cerebral Palsy—A Population-Based Study”
by Ana Dos Santos Rufino, Magnus Påhlman, Ingrid Olsson and Kate Himmelmann
J. Clin. Med. 2023, 12(1), 346; https://doi.org/10.3390/jcm12010346
Full text available online: https://www.mdpi.com/2077-0383/12/1/346

4. “Therapeutic Strategies in Children with Epilepsy: A Quality-of-Life-Related Perspective”
by Hideaki Kanemura
J. Clin. Med. 2024, 13(2), 405; https://doi.org/10.3390/jcm13020405
Full text available online: https://www.mdpi.com/2077-0383/13/2/405

5. “Cenobamate Plasma Levels in Patients with Epilepsy: Correlation with Efficacy and Tolerability?”
by Bernhard J. Steinhoff, Dimitra Georgiou, Daniel Dietmann and Tassanai Intravooth
J. Clin. Med. 2024, 13(10), 2757; https://doi.org/10.3390/jcm13102757
Full text available online: https://www.mdpi.com/2077-0383/13/10/2757

6. “Cognitive Impairment in People with Epilepsy”
by Ajda Novak, Karmen Vizjak and Martin Rakusa
J. Clin. Med. 2022, 11(1), 267; https://doi.org/10.3390/jcm11010267
Full text available online: https://www.mdpi.com/2077-0383/11/1/267

7. “Detecting Reasons for Nonadherence to Medication in Adults with Epilepsy: A Review of Self-Report Measures and Key Predictors”
by Sarah Mendorf, Tino Prell and Aline Schönenberg
J. Clin. Med. 2022, 11(15), 4308; https://doi.org/10.3390/jcm11154308
Full text available online: https://www.mdpi.com/2077-0383/11/15/4308

8. “Vagus Nerve Stimulation for Drug Resistant Epilepsy: Clinical Outcome, Adverse Events, and Potential Prognostic Factors in a Single Center Experience”
by Ming Shan, Hongliang Mao, Hutao Xie, Yifei Gan, Delong Wu, Jian Song, Yutong Bai and Jianguo Zhang
J. Clin. Med. 2022, 11(24), 7536; https://doi.org/10.3390/jcm11247536
Full text available online: https://www.mdpi.com/2077-0383/11/24/7536

9. “Early Epilepsy Surgery in Benign Cerebral Tumors: Avoid Your ‘Low-Grade’ Becoming a ‘Long-Term’ Epilepsy-Associated Tumor”
by Catrin Mann, Nadine Conradi, Elisabeth Neuhaus, Jürgen Konczalla, Thomas M. Freiman, Andrea Spyrantis, Katharina Weber, Patrick Harter, Felix Rosenow, Adam Strzelczyk et al.
J. Clin. Med. 2022, 11(19), 5892; https://doi.org/10.3390/jcm11195892
Full text available online: https://www.mdpi.com/2077-0383/11/19/5892

10. “A Multi-Disciplinary Team Approach to Genomic Testing for Drug-Resistant Epilepsy Patients—The GENIE Study”
by Lata Vadlamudi, Carmen Maree Bennett, Melanie Tom, Ghusoon Abdulrasool, Kristian Brion, Ben Lundie, Hnin Aung, Chiyan Lau, Jonathan Rodgers, Kate Riney et al.
J. Clin. Med. 2022, 11(14), 4238; https://doi.org/10.3390/jcm11144238
Full text available online: https://www.mdpi.com/2077-0383/11/14/4238

Special Issues:

Clinical Therapeutic and Management Strategies of Epilepsy—Social and Neuropsychological
Aspects

Guest Editor: Dr. Hideaki Kanemura
Submission deadline: 20 May 2025

Neurosurgery: Current Challenges and New Perspectives
Guest Editors: Dr. Adip G. Bhargav and Prof. Dr. Paul J. Camarata
Submission deadline: 30 June 2025

18 February 2025
Journal of Clinical Medicine | Issue Cover Articles in 2024 (II)


Journal of Clinical Medicine
(JCM, ISSN: 2077-0383) is a semimonthly journal, published online by MDPI. The Editorial Office has selected 24 articles as issue cover articles in 2024. We welcome you to read the second part of these articles to learn about the current trends, challenges, and innovative solutions in clinical medicine. To access the full Volume 13, please visit https://www.mdpi.com/2077-0383/13.

1. “Diagnosis of Pulmonary Embolism: A Review of Evidence-Based Approaches”
by Sneha E. Thomas, Ido Weinberg, Robert M. Schainfeld, Kenneth Rosenfield and Gaurav M. Parmar
J. Clin. Med. 2024, 13(13), 3722; https://doi.org/10.3390/jcm13133722
Available online: https://www.mdpi.com/2077-0383/13/13/3722

2. “A Review of Myositis-Associated Interstitial Lung Disease”
by Renuka Kannappan, Raagni Kumar, Kimberly Cichelli and Lawrence H. Brent
J. Clin. Med.
2024, 13(14), 4055; https://doi.org/10.3390/jcm13144055
Available online: https://www.mdpi.com/2077-0383/13/14/4055

3. “Visual Outcomes of Cataract Surgery in Patients with Previous History of Implantable Collamer Lens”
by Norma E. Del Risco, Chad L. Talbot, Kayvon A. Moin, Garrett N. Manion, Alex H Brown, Stephen M. Walker, Ping-Shou Zhong, Hanting Zhang, Phillip C. Hoopes and Majid Moshirfar
J. Clin. Med. 2024, 13(15), 4292; https://doi.org/10.3390/jcm13154292
Available online: https://www.mdpi.com/2077-0383/13/15/4292

4. “Could Vaccination against COVID-19 Trigger Immune-Mediated Inflammatory Diseases?”
by Aikaterini I. Liakou, Andreas G. Tsantes, Eleni Routsi, Efthymia Agiasofitou, Magdalini Kalamata, Evangelia-Konstantina Bompou, Konstantina A. Tsante, Soultana Vladeni, Eleni Chatzidimitriou, Ourania Kotsafti et al.
J. Clin. Med. 2024, 13(16), 4617; https://doi.org/10.3390/jcm13164617
Available online: https://www.mdpi.com/2077-0383/13/16/4617

5. “Transthoracic Cross Clamp versus Endoaortic Balloon Occlusion in Minimally Invasive Mitral Valve Surgery: A Pooled Study with Subgroup Analyses”
by Dimitrios E. Magouliotis, Serge Sicouri, Massimo Baudo, Yoshiyuki Yamashita, Andrew Xanthopoulos, Arian Arjomandi Rad, Thanos Athanasiou and Basel Ramlawi
J. Clin. Med. 2024, 13(17), 4989; https://doi.org/10.3390/jcm13174989
Available online: https://www.mdpi.com/2077-0383/13/17/4989

6. “Hospitalization and Health Resource Utilization in Emergency Department Cases of Diabetic Foot Infections in the U.S. from 2012 to 2021: A Nationally Representative Analysis”
by Matthew C. Dickson and Grant H. Skrepnek
J. Clin. Med. 2024, 13(18), 5361; https://doi.org/10.3390/jcm13185361
Available online: https://www.mdpi.com/2077-0383/13/18/5361

7. “Chiropractic and Spinal Manipulation: A Review of Research Trends, Evidence Gaps, and Guideline Recommendations”
by Robert J. Trager, Geronimo Bejarano, Romeo-Paolo T. Perfecto, Elizabeth R. Blackwood and Christine M. Goertz
J. Clin. Med. 2024, 13(19), 5668; https://doi.org/10.3390/jcm13195668
Available online: https://www.mdpi.com/2077-0383/13/19/5668

8. “Association of Hypertension with Different Cognitive Disorders”
by Lillian Huang and Wilbert S. Aronow
J. Clin. Med. 2024, 13(20), 6029; https://doi.org/10.3390/jcm13206029
Available online: https://www.mdpi.com/2077-0383/13/20/6029

9. “Chest Tubes and Pleural Drainage: History and Current Status in Pleural Disease Management”
by Claudio Sorino, David Feller-Kopman, Federico Mei, Michele Mondoni, Sergio Agati, Giampietro Marchetti and Najib M. Rahman
J. Clin. Med. 2024, 13(21), 6331; https://doi.org/10.3390/jcm13216331
Available online: https://www.mdpi.com/2077-0383/13/21/6331

10. “Challenges and Considerations in Diagnosing and Managing p16+-Related Oropharyngeal Squamous Cell Carcinoma (OPSCC) with Neck Metastasis: Implications of p16 Positivity, Tobacco Exposure, and De-Escalation Strategies”
by Giovanni Motta, Benedetta Brandolini, Tonia Di Meglio, Salvatore Allosso, Massimo Mesolella, Filippo Ricciardiello, Marco Bocchetti, Domenico Testa and Gaetano Motta
J. Clin. Med. 2024, 13(22), 6773; https://doi.org/10.3390/jcm13226773
Available online: https://www.mdpi.com/2077-0383/13/22/6773

11. “Comparative Analysis of Real-World Clinical Outcomes of a Novel Pulsed Field Ablation System for Pulmonary Vein Isolation: The Prospective CIRCLE-PVI Study”
by Lyuboslav Katov, Yannick Teumer, Carlo Bothner, Wolfgang Rottbauer and Karolina Weinmann-Emhardt
J. Clin. Med. 2024, 13(23), 7040; https://doi.org/10.3390/jcm13237040
Available online: https://www.mdpi.com/2077-0383/13/23/7040

12. “Screening for Alcohol Use Disorder Among Hospitalised Patients: Learning from a Retrospective Cohort Study in Secondary Care”
by Mohsan Subhani, Dipaka Rani Nath, Usman Talat, Aqsa Imtiaz, Amardeep Khanna, Awais Ali, Guruprasad P. Aithal, Stephen D. Ryder and Joanne R. Morling
J. Clin. Med. 2024, 13(24), 7617; https://doi.org/10.3390/jcm13247617
Available online: https://www.mdpi.com/2077-0383/13/24/7617

17 February 2025
MDPI Celebrates Excellence in Medical Research with Early Career Researcher Awards


MDPI, a pioneer in scholarly open access publishing, and the Lee Kong Chian School of Medicine (LKCMedicine), Singapore, proudly announce the successful conclusion of the first edition the MDPI Early Career Researcher Awards. The awards, which recognize outstanding contributions to medical and biomedical research, were presented to six exceptional researchers during an awards ceremony held at LKCMedicine HQ Building on 28 November 2024.

Honoring Excellence in Research

The awards recognize exceptional postdoctoral researchers and Ph.D. students who have demonstrated outstanding originality, innovation, and impact in their respective fields. We are honored to announce the winners of the 2024 edition:

Early Career Researcher (Postdoc) Award:

  • Dr. Theresia Handayani Mina, “Adiposity and Metabolic Health in Asian Populations: An Epidemiological Study Using Dual-Energy X-Ray Absorptiometry in Singapore”;
  • Dr. Erfan Rezvani Ghomi, “Wound Healing Improvement by Novel Aligned Antimicrobial Nanofibrous 3D Scaffolds”;
  • Dr. Yadollah Ranjbar Slamloo, “Functional Alterations of The Prefrontal Circuit Underlying Cognitive Aging in Mice”.

Early Career Researcher (Ph.D.) Award:

  • Pritisha Rozario, “Mechanistic Basis for Potassium Efflux-Driven Activation of the Human NLRP1 Inflammasome”;
  • Michelle Law Cheok Yien, “Chikungunya Virus Nonstructural Protein 1 is a Versatile RNA Capping and Decapping Enzyme”;
  • Yin Ruoyu, “The Use of Digital Mental Health and Wellbeing Tools in Older Adults: A Mixed Method Study”.

Our collaboration highlights a shared commitment to recognizing exceptional talent and research within the academic community, addressing today’s healthcare challenges, and inspiring continued innovation.

Looking Ahead to 2025

Building on the success of the first edition, MDPI and LKCMedicine are excited to announce that the 2025 MDPI Early Researcher Awards will continue to celebrate excellence and innovation in medical research. The next edition promises to expand its scope, introducing new categories and providing even greater recognition for impactful research.

Further details on the 2025 awards, including nomination criteria and timelines, will be shared in the coming months. We remain committed to fostering a culture of research excellence and collaboration within the global scientific community.

13 February 2025
Journal of Clinical Medicine | Title Story Articles for the Second Half of 2024


We are delighted to share a list of title story articles, selected from the publications in the second half of 2024, for display at the top of the homepage of Journal of Clinical Medicine (JCM, ISSN: 2077-0383). These articles cover a wide range of topics at the heart of the most recent trends in medical research, including vitiligo, ablation, low back pain, and heart failure. All of these articles can be accessed online by clicking on the appropriate link. We hope that medical practitioners, researchers, and those who are curious about medical knowledge can be inspired by these articles.

1. “Vitiligo: From Pathogenesis to Treatment”
by Reinhart Speeckaert, Elise Van Caelenberg, Arno Belpaire, Marijn M. Speeckaert and Nanja van Geel
J. Clin. Med. 2024, 13(17), 5225; https://doi.org/10.3390/jcm13175225
Full text available online: https://www.mdpi.com/2077-0383/13/17/5225

2. “Pulsed Field Ablation: A Comprehensive Update”
by Fatima M. Ezzeddine, Samuel J. Asirvatham and Duy T. Nguyen
J. Clin. Med. 2024, 13(17), 5191; https://doi.org/10.3390/jcm13175191
Full text available online: https://www.mdpi.com/2077-0383/13/17/5191

3. “The Importance of Mind–Body in Pilates Method in Patients with Chronic Non-Specific Low Back Pain—A Randomized Controlled Trial”
by Pablo Vera-Saura, Jesús Agudo-Pavón, Dara María Velázquez-Torres, María Martín-Alemán, Felipe León-Morillas, Aday Infante-Guedes and David Cruz-Díaz
J. Clin. Med. 2024, 13(16), 4731; https://doi.org/10.3390/jcm13164731
Full text available online: https://www.mdpi.com/2077-0383/13/16/4731

4. “Bronchoscopic Diagnosis of Severe Respiratory Infections”
by Maire Röder, Anthony Yong Kheng Cordero Ng and Andrew Conway Morris
J. Clin. Med. 2024, 13(19), 6020; https://doi.org/10.3390/jcm13196020
Full text available online: https://www.mdpi.com/2077-0383/13/19/6020

5. “Acute Ischemic Stroke during Extracorporeal Membrane Oxygenation (ECMO): A Narrative Review of the Literature”
by Konstantinos Themas, Marios Zisis, Christos Kourek, Giorgos Konstantinou, Lucio D’Anna, Panagiotis Papanagiotou, George Ntaios, Stavros Dimopoulos and Eleni Korompoki
J. Clin. Med. 2024, 13(19), 6014; https://doi.org/10.3390/jcm13196014
Full text available online: https://www.mdpi.com/2077-0383/13/19/6014

6. “Physiology-Guided Resuscitation: Monitoring and Augmenting Perfusion during Cardiopulmonary Arrest”
by Samuel Bernard, Raymond A. Pashun, Bhavya Varma and Eugene Yuriditsky
J. Clin. Med. 2024, 13(12), 3527; https://doi.org/10.3390/jcm13123527
Full text available online: https://www.mdpi.com/2077-0383/13/12/3527

7. “Bridge to Life: Current Landscape of Temporary Mechanical Circulatory Support in Heart-Failure-Related Cardiogenic Shock”
by Panayotis K. Vlachakis, Panagiotis Theofilis, Ioannis Leontsinis, Maria Drakopoulou, Paschalis Karakasis, Evangelos Oikonomou, Christina Chrysohoou, Konstantinos Tsioufis and Dimitris Tousoulis
J. Clin. Med. 2024, 13(14), 4120; https://doi.org/10.3390/jcm13144120
Full text available online: https://www.mdpi.com/2077-0383/13/14/4120

8. “Dobutamine in the Management of Advanced Heart Failure”
by Tanjeev Ahmad, Shamitha A. Manohar, Jason D. Stencel and Thierry H. Le Jemtel
J. Clin. Med. 2024, 13(13), 3782; https://doi.org/10.3390/jcm13133782
Full text available online: https://www.mdpi.com/2077-0383/13/13/3782

7 February 2025
Journal of Clinical Medicine | Highly Cited Papers in 2024 and Hot Topic Special Issues in the Section “Cardiovascular Medicine”


We are delighted to share some highly cited papers from the “Cardiovascular Medicine” Section that were published in the Journal of Clinical Medicine (JCM, ISSN: 2077-0383) in 2024. You are welcome to read these highly cited papers and find the latest publications through this link: https://www.mdpi.com/search?journal=jcm&section=1662. Additionally, some Special Issues in the “Cardiovascular Medicine” Section are currently open for submissions. The following is a list of articles and Special Issues that we believe may interest you:

1. “Systemic Immune-Inflammation Index and Systemic Inflammatory Response Index as Predictors of Mortality in ST-Elevation Myocardial Infarction”
by Federica Marchi, Nataliya Pylypiv, Alessandra Parlanti, Simona Storti, Melania Gaggini, Umberto Paradossi, Sergio Berti and Cristina Vassalle
J. Clin. Med. 2024, 13(5), 1256; https://doi.org/10.3390/jcm13051256
Full text available online: https://www.mdpi.com/2077-0383/13/5/1256

2. “The Effects of Obstructive Sleep Apnea on the Cardiovascular System: A Comprehensive Review”
by Michael V. DiCaro, KaChon Lei, Brianna Yee and Tahir Tak
J. Clin. Med. 2024, 13(11), 3223; https://doi.org/10.3390/jcm13113223
Full text available online: https://www.mdpi.com/2077-0383/13/11/3223

3. “Optical Coherence Tomography in Myocardial Infarction Management: Enhancing Precision in Percutaneous Coronary Intervention”
by Angela Buonpane, Giancarlo Trimarchi, Marco Ciardetti, Michele Alessandro Coceani, Giulia Alagna, Giovanni Benedetti, Sergio Berti, Giuseppe Andò, Francesco Burzotta and Alberto Ranieri De Caterina
J. Clin. Med. 2024, 13(19), 5791; https://doi.org/10.3390/jcm13195791
Full text available online: https://www.mdpi.com/2077-0383/13/19/5791

4. “Advanced Lung Cancer Inflammation Index as Predictor of All-Cause Mortality in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention”
by Giancarlo Trimarchi, Fausto Pizzino, Alessio Lilli, Alberto Ranieri De Caterina, Augusto Esposito, Stefano Dalmiani, Annamaria Mazzone, Gianluca Di Bella, Sergio Berti and Umberto Paradossi
J. Clin. Med. 2024, 13(20), 6059; https://doi.org/10.3390/jcm13206059
Full text available online: https://www.mdpi.com/2077-0383/13/20/6059

5. “Pregnancy Arrhythmias: Management in the Emergency Department and Critical Care”
by Elena Conti, Nunzio Dario Cascio, Patrizia Paluan, Giulia Racca, Yaroslava Longhitano, Gabriele Savioli, Manfredi Tesauro, Roberto Leo, Fabrizio Racca and Christian Zanza
J. Clin. Med. 2024, 13(4), 1095; https://doi.org/10.3390/jcm13041095
Full text available online: https://www.mdpi.com/2077-0383/13/4/1095

6. “Rosuvastatin-Based Lipid-Lowering Therapy for the Control of LDL Cholesterol in Patients at High Vascular Risk”
by Jose María Mostaza and Carlos Escobar
J. Clin. Med. 2024, 13(7), 1894; https://doi.org/10.3390/jcm13071894
Full text available online: https://www.mdpi.com/2077-0383/13/7/1894

7. “Obesity in Hypertensive Patients Is Characterized by a Dawn Phenomenon in Systolic Blood Pressure Values and Variability”
by Dawid Lipski, Dorota Marzyńska, Paulina Sytek, Patrycja Rzesoś, Agnieszka Rabiza, Sebastian Żurek, Artur Radziemski, Łukasz Stryczyński, Andrzej Tykarski and Paweł Uruski
J. Clin. Med. 2024, 13(2), 371; https://doi.org/10.3390/jcm13020371
Full text available online: https://www.mdpi.com/2077-0383/13/2/371

8. “Heart Rate Variability and Cognition: A Narrative Systematic Review of Longitudinal Studies”
by Paola Nicolini, Gabriella Malfatto and Tiziano Lucchi
J. Clin. Med. 2024, 13(1), 280; https://doi.org/10.3390/jcm13010280
Full text available online: https://www.mdpi.com/2077-0383/13/1/280

9. “Multiparametric Monitoring of Disease Progression in Contemporary Patients with Wild-Type Transthyretin Amyloid Cardiomyopathy Initiating Tafamidis Treatment”
by Svenja Ney, Roman Johannes Gertz, Lenhard Pennig, Richard J. Nies, Udo Holtick, Linus A. Völker, Gilbert Wunderlich, Katharina Seuthe, Christopher Hohmann, Clemens Metze et al.
J. Clin. Med. 2024, 13(1), 284; https://doi.org/10.3390/jcm13010284
Full text available online: https://www.mdpi.com/2077-0383/13/1/284

10. “Focal Pulsed Field Ablation for Atrial Arrhythmias: Efficacy and Safety under Deep Sedation”
by Sebastian Weyand, Viola Adam, Paloma Biehler, Patricia Hägele, Simon Hanger, David Heinzmann, Stephanie Löbig, Andrei Pinchuk, Christian Waechter and Peter Seizer
J. Clin. Med. 2024, 13(2), 576; https://doi.org/10.3390/jcm13020576
Full text available online: https://www.mdpi.com/2077-0383/13/2/576

Special Issues:
Advances in the Diagnosis and Treatment of Pulmonary Hypertension
Guest Editors: Dr. Takayuki Fujiwara
and Dr. Shun Minatsuki
Submission deadline: 31 March 2025
Cardiovascular Disease and Diabetes: Management of Risk Factors
Guest Editors: Dr. Alfredo Caturano and Dr. Teresa Salvatore
Submission deadline: 20 April 2025
Advanced Techniques for the Treatment of Complex Coronary Artery Disease: 2nd Edition
Guest Editor: Dr. Simone Calcagno
Submission deadline: 31 May 2025
Current Trends and Innovations in Coronary Artery Disease and Myocardial Ischemia
Guest Editor: Dr. Edoardo Conte
Submission deadline: 30 June 2025

5 February 2025
MDPI INSIGHTS: The CEO's Letter #20 - Beijing, Singapore, Bangkok, JAMS, Jisc

Welcome to the MDPI Insights: The CEO's Letter.

In these monthly letters, I will showcase two key aspects of our work at MDPI: our commitment to empowering researchers and our determination to facilitating open scientific exchange.


Opening Thoughts

2024 Annual Meeting – Beijing (15 January 2025)

You haven’t truly experienced a New Year’s celebration until you’ve attended one of MDPI’s Chinese Annual Meeting festivities. This year I visited our annual meeting in Beijing, held on the 15th of January.

Imagine this: stepping into a banquet hall filled with 140 tables and about 1,400 colleagues from our Beijing offices, all gathered to share in a six-hour event. The agenda included year-end speeches and presentations, a variety of performances by our colleagues, a selection of awards honouring local employees for their work, group photos for the memories, and a dinner.

This may have been one of the largest events I have attended. For those unaccustomed to such an event, it might seem overwhelming, but it was quite the opposite. The atmosphere was one of celebration as everyone came together to support their peers and celebrate the achievements of 2024.

I was honoured to deliver the opening speech and a presentation highlighting our growth and investment in MDPI’s most valuable asset: our people.

“Our editorial teams represent MDPI at its finest”

I want to give special recognition to the editorial department, across all of our offices, which forms the heart of our business. These teams are the frontline communicators with our authors, reviewers, and guest editors, creating a smooth experience of processing our manuscripts. Their professionalism and kindness are often highlighted as key drivers of satisfaction with MDPI. For this, I extend my deepest gratitude to all our editorial staff, across every office. They truly represent MDPI at its finest.

Beijing is home to two of our offices, with just over 800 employees in Tongzhou and over 600 in Haidian. Thank you to our administrative teams and everyone involved in organizing these New Year’s celebrations across all offices. These events provide a moment to reflect on our shared accomplishments and appreciate the positive impact each of you has on our culture.

MDPI Offices in China

While the history of MDPI begins in Basel, Switzerland, the story of MDPI is very much rooted in China. Below is a list of MDPI’s current offices in China and their respective dates of inauguration:

  • 2008: Beijing (Tongzhou, Haidian)
  • 2013: Wuhan (Hankou, Guanggu)
  • 2019: Tianjin
  • 2021: Dalian
  • 2021: Nanjing

To date, over 381,000 MDPI research articles have been published by authors affiliated with Chinese institutions, making China our largest market. This is reflected not only in the volume of publications but also in the scale of our workforce supporting local operations and contributing to global success.

While no new offices in China were launched between 2022 and 2024 due to the pandemic and strategic planning, we remain committed to future growth here. Our plans include expanding operations as we continue to build our global workforce.

We look forward to a year filled with continued collaboration, growth, and shared success.

“We remain committed to future growth in China”

Impactful Research

MDPI and Jisc Consortium Extend Open Access Agreement for 2025

I’m pleased to share that MDPI has extended its agreement with the Jisc consortium in the UK for 2025. This renewal strengthens our partnership with UK institutions and reaffirms our shared commitment to advancing open access publishing.

Jisc is the UK’s not-for-profit digital, data, and technology agency supporting tertiary education, research, and innovation. Through initiatives such as our agreement, Jisc helps institutions access essential digital resources and infrastructure to support researchers. Currently, 62 UK institutions are part of our Institutional Open Access Program (IOAP) through this partnership.

Authors from participating institutions benefit from discounts on article processing charges (APCs), with even greater support for institutions that centrally fund APCs. This helps researchers focus on their work while simplifying the publishing process.

A full list of participating institutions can be found here.

As Becky Castellon, our Institutional Partnerships Manager, puts it: “Extending our agreement with Jisc is a reward for the strong partnership we’ve built with research institutions throughout the UK.”

At MDPI, we are dedicated to making research more accessible while reducing administrative burdens for institutions and authors. Open access publishing is at the heart of what we do, and we’re proud to expand its reach in the UK and beyond.

Inside MDPI

Visit to MDPI's Singapore office

During my January trip to some of our APAC offices, I also had the pleasure of visiting our Singapore office for the first time. It’s exciting to see how much the team has grown, now numbering over 55 staff members, with more joining us in February.

Welcoming and Supporting New Team Members

“Experienced staff play an important role in mentoring new hires”

I had the opportunity to connect with both experienced colleagues and new team members who are currently embarking on their careers. This visit reminded me of what it was like when I was in their shoes. I encourage all of us to engage new colleagues with empathy, as we have all been in their position. By creating a welcoming and supportive environment, we can help them settle in and learn about the corporate world, MDPI and our mission.

Experienced staff play an important role in mentoring and guiding new hires, most of whom are transitioning from academia to their first job. I’m especially grateful to colleagues such as Colin Chen, Alicia Ren, Yu Nwe Soe, Colin Wee, Amy Cham and other senior members who have contributed to shaping the culture and work environment in Singapore.

Building MDPI’s Positive Reputation

During my visit, I spoke with the office staff about the importance of their roles in building a positive reputation that helps create trust in MDPI. I shared how every interaction and communication point contributes to the marketing of MDPI and our journals. I also highlighted the career development opportunities available as MDPI continues to grow.

Connecting with the Singapore Marketing Team

I also spent time connecting directly with the Singapore Marketing team, which has quickly grown to 15 young and ambitious members. They are eager to learn and are actively contributing to our journal and corporate marketing activities. I shared insights into our corporate marketing structure and strategy and look forward to supporting them as they grow. 

During the visit, I was joined by my colleague Dr. Constanze Schelhorn, Head of Indexing, who provided training on indexing. This training was greatly appreciated by the local staff.

Meeting with Prof. Dr. Manoj Gupta

Lastly, we had the privilege of meeting Prof. Dr. Manoj Gupta, Editor-in-Chief (EiC) of Technologies since 2016 and Section EiC of Metals.

Prof. Gupta is an active decision-maker for the journal and a great brand ambassador for MDPI.

Prof. Gupta has helped sustainably scale Technologies, which now has a 4.2 Impact Factor and a 6.7 CiteScore, ranking Q1 in the JCR category of Engineering and Q1 in the CiteScore category of Computer Science.

During our meeting, we discussed strategies for Institutional Open Access Partnership agreements and ways to promote MDPI journals in Singapore.

PS. During the visit, we also had the chance to participate in Lo Hei, also known as Yee Sang or the “prosperity toss.” This is a raw fish salad traditionally enjoyed during Chinese New Year and is particularly popular among Chinese communities in Singapore, Malaysia, and Indonesia. Everyone gathers around the table as the ingredients are added one by one, and then the salad is mixed together. It was a fun experience to take part in this New Year tradition!

 

Coming Together for Science

JAMS – Journal & Article Management System

I am excited to announce the official relaunch of JAMS (Journal & Article Management System), one of MDPI’s key initiatives to support academic publishers worldwide.

With this relaunch, JAMS now offers new pricing models and flexible solutions for small-scale journals, commercial publishers, and university presses. We have also redesigned the JAMS website to enhance the user experience.

“JAMS is a testament to our commitment to simplifying the publishing process”

Explore the new website here: jams.pub

It’s also great to see the JAMS team expanding our presence at conferences and on social media to engage more effectively with the academic community.

Recently, Facundo Santomé (Senior Marketing Manager) and Alex Ramos (Senior Marketing Specialist) represented JAMS at the APE 2025 conference in Berlin, highlighting how our platform empowers small and independent publishers to streamline and scale their journal management.

JAMS was built to change that by adapting to the unique requirements of each publisher.

At MDPI, we continually invest in our growth – not only by expanding our operations and staff but also by developing innovative products that serve the academic and publishing community at large. JAMS, with its comprehensive suite of journal management tools, is a testament to our commitment to simplifying the publishing process for our partners.

Imagine a submission system that frees up your time for strategy, innovation, and impactful publishing.

Under the leadership of Silvano Bonfatti (Product Manager, MDPI), the JAMS team has conducted in-depth market research to understand the challenges publishers face: endless administrative tasks, inefficient workflows, and systems that don’t always meet their needs.

If you believe JAMS could benefit any of your network contacts, please share our website. Contact the JAMS team. They are always ready to assist with your publishing needs.

What Sets JAMS Apart?

  • Scalability – Whether you're a niche journal or managing thousands of submissions, JAMS grows with you.
  • End-to-End Workflow – From submission to peer review and final publication, everything is in one place.
  • Automation That Works for You – Say goodbye to chasing reviewers and formatting issues, so that you can focus on quality instead.
  • Built by Publishers, for Publishers – JAMS is backed by MDPI’s expertise; we know exactly what it takes to run a journal smoothly.
  • Flexible & Fair Pricing – Supporting journals of all sizes, with special rates for non-profits and publishers in the Global South.

Partners Who Already Trust JAMS

If you believe JAMS could benefit any of your network contacts, please share our website. Contact the JAMS team. They are always ready to assist with your publishing needs.

Closing Thoughts

Visit to MDPI's Bangkok office

To conclude my APAC trip, I had the pleasure of visiting our Bangkok office from 22 to 24 January. The office has grown significantly, closing 2024 with a total of 445 colleagues across various departments, including Editorial, Production, Conference, Training, Journal Relationship Specialists (JRS), Managing Editors, and supporting teams in HR, Admin, IT, and Finance.

I would like to praise our Bangkok management team for their excellent work in supporting our growth and creating a positive work environment. Our colleagues here are humble, talented, hardworking, and appreciative of MDPI’s mission.

Thailand was among MDPI’s top 30 markets in 2024 for total publications. With our office in Bangkok, we have an opportunity to further promote open access while supporting local researchers and institutions. This includes open access discounts, author training sessions, conference sponsorships, and other initiatives. We currently have 25 Editorial Board Members (EBMs) from Thailand and will work on expanding this network.

Engaging with Group Leads

“Group leads play an important role in creating a safe, positive environment”

During my visit, I met with our group leads to highlight their crucial role in managing journal performance and mentoring new employees, especially given our increased hiring targets. Many new hires are early in their careers and require training, development, and support. Group leads play an important role in creating a safe, positive environment that fosters professional growth while maintaining MDPI’s reputation for service quality.

To wrap up the session, I added a personal touch by holding the door and giving everyone high-fives – a small gesture to show appreciation, boost morale, and strengthen team spirit. It’s important for our colleagues to feel seen, heard, and valued.

University Visit: King Mongkut’s University of Technology North Bangkok (KMUTNB)

We also visited King Mongkut’s University of Technology North Bangkok (KMUTNB) to explore collaboration opportunities.

Our discussions focused on: Institutional Open Access Partnership (IOAP), Author training sessions, Conference sponsorships, Student employment initiatives, and more.

This visit reinforced the importance of building strong relationships with local universities, ensuring we continue to support and engage with the academic community in Thailand.

“My time in Bangkok was productive and inspiring”

My time in Bangkok was productive and inspiring. The senior team has done a great job in growing the office and creating a supportive, high-performing environment. I look forward to seeing continued success from our colleagues in Thailand.

Stefan Tochev
Chief Executive Officer
MDPI AG

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