Anaemia in Focus: Challenges and Solutions in Haematology

Dear Colleagues,

Anaemia, derived from the Greek word <αν-αίμα>, meaning “without blood”, is defined as low haemoglobin (Hb) levels below specific cut-off points adjusted for age, sex, physiological status, and altitude. It remains a critical global public health issue with a multifactorial aetiology requiring collaboration among physicians to identify and address its causes effectively. Challenges in haematology include managing iron-deficiency anaemia (IDA) in vulnerable populations, addressing anaemia of chronic disease (ACD), and treating genetic disorders like sickle cell anaemia and thalassemia. Limited access to diagnostics and treatments in low-resource settings and health inequities further complicate care. Overuse of blood transfusions and resistance to oral iron supplements also pose difficulties. Solutions involve advanced diagnostics, novel therapies like HIF-prolyl hydroxylase inhibitors, public health initiatives, and emerging technologies such as gene editing and telemedicine. A comprehensive, multidisciplinary approach is essential to improve outcomes and ensure equitable access to care globally.

This Special Issue aims to collect and publish original research articles and reviews demonstrating recent advances in our knowledge on new diagnostic and therapeutic approaches in these clinical conditions with particular regard to the personalization of the patient's treatment on the basis of their clinical characteristics, comorbidities, and preference.

Dr. Efthymia Vlachaki
Guest Editor

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