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Journal of Clinical Medicine, Volume 14, Issue 20

October-2 2025 - 323 articles

Cover Story: Artificial intelligence (AI) is increasingly applied to enhance diagnostic accuracy and efficiency. This study aimed to evaluate the precision of an AI-based method for assessing facial asymmetry. A total of 130 patients were analyzed using 3D facial images captured with the Vectra® M3 system, comparing manual and AI-based methods. Seven bilateral landmarks were identified manually to calculate an asymmetry index, while the AI algorithm automatically detected the same landmarks and computed the index. The accuracy of automated landmark identification was compared with manual measurements. The results demonstrated strong agreement between the two methods for five landmarks. The AI-based approach provides an efficient and reliable tool for facial asymmetry analysis using 3D imaging. View this paper
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Articles (323)

  • Article
  • Open Access
843 Views
10 Pages

21 October 2025

Objective: As the survival of individuals born with congenital heart disease (CHD) improves into adulthood, the focus has shifted from traditional clinical outcomes to patient-reported outcome measures that better reflect the impact of the disease on...

  • Systematic Review
  • Open Access
958 Views
14 Pages

Breastfeeding During and After Breast Cancer Diagnosis—A Systematic Review of the Literature

  • Anna Ampatzi,
  • Nikoleta Aikaterini Xixi,
  • Rozeta Sokou,
  • Eleni Karapati,
  • Zoi Iliodromiti,
  • Paraskevi Volaki,
  • Styliani Paliatsiou,
  • Nicoletta Iacovidou and
  • Theodora Boutsikou

21 October 2025

Background/Objectives: Breast cancer diagnosis in lactating women is relatively uncommon. The term Pregnancy-Associated Breast Cancer (PABC) refers to breast cancer diagnosed during pregnancy or within the first year postpartum. There are several fac...

  • Article
  • Open Access
1 Citations
510 Views
22 Pages

Comparative Biomechanical Evaluation of Bicortical Screw Versus Plate Fixation in Jones Fractures of the Fifth Metatarsal Using 3D-Printed Models

  • Robert Daniel Dobrotă,
  • Mark Pogărășteanu,
  • Dumitru Ferechide,
  • Ioana-Codruța Lebada and
  • Marius Moga

21 October 2025

Background: Jones fractures of the 5th metatarsal are frequently associated with nonunion due to limited vascularization and repetitive mechanical stress. The aim of the study was to compare the biomechanical performance of T-plate and bicortical scr...

  • Article
  • Open Access
776 Views
12 Pages

Surgical Pulmonary Embolectomy Versus Systemic Thrombolysis in High-Risk Pulmonary Embolism: A Retrospective Single-Center Analysis

  • Arash Motekallemi,
  • Linus C. Markus Rohrwild,
  • Jonas Ajouri,
  • Ridvan Dryana,
  • Tamari Tvildiani,
  • Verena Vach,
  • Ralf M. Muellenbach and
  • Ali Asghar Peivandi

21 October 2025

Background: Pulmonary embolism (PE) is a life-threatening condition with high mortality, particularly in high-risk cases where rapid clinical deterioration is common. The optimal management strategy for high-risk PE remains debated. Systemic thrombol...

  • Protocol
  • Open Access
1 Citations
1,317 Views
15 Pages

Sleep Disturbances Across Dementias and Cognitive Decline: Study Protocol for a Systematic Review and Network Meta-Analysis of Polysomnographic Findings

  • Annibale Antonioni,
  • Arianna Della Valle,
  • Caterina Leitner,
  • Emanuela Maria Raho,
  • Edward Cesnik,
  • Jay Guido Capone,
  • Maria Elena Flacco,
  • Francesca Casoni,
  • Paola Proserpio and
  • Luigi Ferini-Strambi
  • + 1 author

21 October 2025

Sleep disturbances are increasingly recognized as early and clinically meaningful features in the pathophysiology of neurodegenerative diseases. Polysomnography (PSG), i.e., the gold standard for objectively characterizing sleep architecture, may pro...

  • Feature Paper
  • Article
  • Open Access
552 Views
15 Pages

Interventions for Fontan Pathway Obstruction in Patients Following Total Cavopulmonary Connection

  • Nicole Piber,
  • Christina Ruda,
  • Thibault Schaeffer,
  • Muneaki Matsubara,
  • Jonas Palm,
  • Teresa Lemmen,
  • Paul Philipp Heinisch,
  • Stanimir Georgiev,
  • Alfred Hager and
  • Peter Ewert
  • + 3 authors

21 October 2025

Background/Objectives: Obstruction of the Fontan pathway is a severe morbidity after total cavopulmonary connection (TCPC). This study aimed to evaluate the incidence and location of TCPC pathway obstruction and corresponding interventions. Methods:...

  • Article
  • Open Access
575 Views
11 Pages

21 October 2025

Background: We aimed to analyze various gait parameters before and after THA for patients with a highly dislocated hip to examine gait recovery and whether it is continued. Methods: This was a retrospective, single-center study. We enrolled 10 patien...

  • Article
  • Open Access
1,059 Views
15 Pages

Home Is Not Always Safe: Pediatric Unintentional Home Injuries in a Tertiary Emergency Department Setting

  • Göksel Vatansever,
  • Erkan Şimşekli,
  • İdil Sivaslı,
  • Ayşe Elçin Özge,
  • Ahmet Hakan Aksu,
  • Adnan Barutçu,
  • İhsan Özdemir,
  • Emre Yaşar Karbancıoğlu,
  • Gülnur Göllü and
  • Ufuk Ateş
  • + 3 authors

21 October 2025

Background/Objectives: Unintentional home injuries (UHIs) are a major yet preventable cause of morbidity and mortality among children. This study aimed to analyze the epidemiological characteristics, injury mechanisms, and clinical outcomes of pediat...

  • Article
  • Open Access
954 Views
22 Pages

Development and Validation of Prognostic Models for Treatment Response of Patients with B-Cell Lymphoma: Standard Statistical and Machine-Learning Approaches

  • Adugnaw Zeleke Alem,
  • Itismita Mohanty,
  • Nalini Pati,
  • Cameron Wellard,
  • Eliza Chung,
  • Eliza A. Hawkes,
  • Zoe K. McQuilten,
  • Erica M. Wood,
  • Stephen Opat and
  • Theophile Niyonsenga

21 October 2025

Background: Achieving a complete response after therapy is an important predictor of long-term survival in lymphoma patients. However, previous predictive models have primarily focused on overall survival (OS) and progression-free survival (PFS), oft...

  • Article
  • Open Access
1,078 Views
13 Pages

Short-Term Outcomes After Transtibial Repair of Medial Meniscus Posterior Root Tears: A Case Series

  • Dan Viorel Nistor,
  • Samuel Piu,
  • Diana Raluca Mihu and
  • Romana von Mengershausen

21 October 2025

Background/Objectives: While arthroscopic repair is established for the treatment of medial meniscus posterior root tears (MMPRT), the relationship between physiotherapy (PT) exposure, meniscal extrusion (ME), and structural healing remains unclear....

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J. Clin. Med. - ISSN 2077-0383