Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.2
2.9
Journals
JCM
Special Issues
Clinical Progress of Spine Surgery
jcm-logo
Submit to Special Issue Submit Abstract to Special Issue Review for JCM Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Clinical Progress of Spine Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: 25 August 2025 | Viewed by 653

Special Issue Editors

Dr. Edoardo Mazzucchi

E-Mail
Guest Editor
Department of Neurosurgery, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy
Interests: neuro-oncology; degenerative spine surgery; functional neurosurgery; pain surgery; image-guided surgery; intraoperative imaging
Special Issues, Collections and Topics in MDPI journals
Dr. Gianluca Vadalà

E-Mail Website
Guest Editor
1. Operative Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy
2. Research Unit of Orthopaedic and Trauma Surgery, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, 00128 Rome, Italy
Interests: spine surgery; orthopedic surgery; intervertebral disk degeneration

Special Issue Information

Dear Colleagues,

Spine surgery is continuously evolving, especially in the last few years. Recent technological advancement has greatly pushed this progress in patient selection, surgical planning, intra-operative imaging, operative room equipment and post-operative care. New and old techniques are being progressively improved over the years to provide less invasive and more efficient surgical treatments. On the other hand, the ageing population and the availability of new treatments for cancer patients have progressively broadened the number of patients who can benefit from surgery both for degenerative and neoplastic conditions, thus posing new challenges to clinicians and researchers. In this Special Issue, we welcome authors to submit papers regarding the progress in the management of spine patients. 

Dr. Edoardo Mazzucchi
Dr. Gianluca Vadalà
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • spine surgery
  • rehabilitation
  • robotic surgery
  • spinal endoscopy
  • spinal tumor
  • back pain
  • minimally invasive surgery
  • spinal fusion

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

13 pages, 1127 KiB  
Article
Comparative Efficacy of Percutaneous Laser Disc Decompression (PLDD) and Conservative Therapy for Lumbar Disc Herniation: A Retrospective, Observational, Single-Center Study
by Domenico Policicchio, Benedetta Boniferro, Erica Lo Turco, Giuseppe Mauro, Antonio Veraldi, Virginia Vescio, Giuseppe Vescio and Giosuè Dipellegrini
J. Clin. Med. 2025, 14(12), 4235; https://doi.org/10.3390/jcm14124235 - 14 Jun 2025
Viewed by 406
Abstract
Background: Although percutaneous laser disc decompression (PLDD) has been proposed as an alternative to conventional surgery for lumbar disc herniation (LDH), we specifically propose it for patients with contained herniations where standard surgical intervention is not the first option. This study evaluates PLDD [...] Read more.
Background: Although percutaneous laser disc decompression (PLDD) has been proposed as an alternative to conventional surgery for lumbar disc herniation (LDH), we specifically propose it for patients with contained herniations where standard surgical intervention is not the first option. This study evaluates PLDD compared to conservative therapy as an early treatment alternative. Methods: This retrospective observational study compared PLDD to conservative treatment in adult patients with contained LDH. All patients underwent 3 months of standard conservative therapy. Those who remained dissatisfied according to the Visual Analog Scale (VAS) and/or Macnab criteria were then treated with PLDD. We analyzed outcomes from both treatment phases using the Wilcoxon signed-rank test and the Mann–Whitney U test. Results: 121 patients underwent outpatient evaluation for LDH and received an average of 90 days of conservative therapy. Of these 103 patients, dissatisfied with the outcomes of conservative treatment, subsequently underwent PLDD. Following conservative treatment, the average VAS score reduction was 4.1%. Six months after PLDD, the VAS scores demonstrated a significant reduction, with an average decrease of 30% (p < 0.0001). In terms of functional outcomes assessed by the Macnab criteria, 39.8% of patients treated with PLDD achieved ‘Excellent’ or ‘Good’ outcomes, compared to only 11.4% after conservative treatment. Conclusions: PLDD appears to be a viable alternative to conservative therapy for this subgroup of patients with contained LDH. It may be beneficial to propose PLDD early in the therapeutic regimen to accelerate short term clinical improvement. Further studies are required to evaluate the long term efficacy of this treatment approach. Full article
(This article belongs to the Special Issue Clinical Progress of Spine Surgery)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop