Innovative Therapies and Management of Complications in Hemoglobinopathies
A special issue of Thalassemia Reports (ISSN 2039-4365). This special issue belongs to the section "Innovative Treatment of Thalassemia".
Deadline for manuscript submissions: closed (31 May 2025) | Viewed by 2036
Special Issue Editors
Interests: thalassemia and sickle cell disease; complications; transfusion medicine; infections; molecular issues of haemo-globinopathies; adverse reactions and other complications of transfusiondpendent thalassaemia; patient blood management; blood donor management; pathogen reduction technologies; transfusion transmitted infections
Interests: transfusion medicine; clinical practices; quality and safety issues; regulatory issues; transfusion education for medical and nursing staff; haemovigilance; epidemiology; blood transfusion in the context of thalassaemia and sickle cell disease; molecular issues of haemoglobinopathies; adverse reactions and other complications of transfusion-dependent thalassaemia; patient blood management; risk management: an important tool for improving quality; blood donor management; pathogen reduction technologies; pathogen inactivation technologies; transfusion transmitted infections; surveillance for substances of human origin (SoHOs): blood, tissues, cells, medically assisted reproduction
Interests: thalassemia and sickle cell disease; complications; transfusion medicine; infections
Interests: thalassemia and sickle cell disease; complications; transfusion medicine; infections; pediatrics
Special Issue Information
Dear Colleagues,
Hemoglobinopathies, such as thalassemia and sickle cell disease, are common genetic disorders that constitute a major healthcare challenge worldwide. Advances in treatments and management strategies, particularly for complications such as transfusional iron overload and secondary iron overload, have improved patient outcomes. However, gaps remain in the management of emerging complications, including hepatocellular carcinoma, cardiovascular issues, and alloimmunization. The aim of this Special Issue is to explore cutting-edge therapies encompassing gene therapy, innovative iron chelation, and pharmacological approaches to improve the management of hemoglobinopathies.
This Special Issue will concentrate on comprehensive strategies for the management of transfusion-related complications and chronic issues that arise, with a focus on long-term patient survival. These will also include multidisciplinary care, early recognition of complications, and improving the safety of blood transfusions. Topics of interest comprise novel therapeutic interventions, long-term monitoring of iron overload, and personalized transfusion protocols to optimize patient outcomes.
Aimed at hematologists, clinical researchers, and allied health professionals, this Special Issue invites original research, systematic reviews, and case reports that bridge the gap between clinical practice and advanced research. It aims to advance knowledge and standards of care for patients with hemoglobinopathies, with an emphasis on improving quality of life and innovative, patient-centered management.
Dr. Sophia Delicou
Prof. Dr. Constantina Politis
Guest Editors
Dr. Aikaterini Xydaki
Dr. Maria Moraki
Guest Editor Assistants
Manuscript Submission Information
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Keywords
- hemoglobinopathies
- thalassemia
- sickle cell disease
- transfusion medicine
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