Announcements

We are pleased to release the list of the 15 most cited papers of Journal of Clinical Medicine (JCM, ISSN: 2077-0383) in 2024.

As an open access academic journal, JCM is dedicated to providing medical researchers with a professional, rapid publication platform. We offer comprehensive support for the dissemination of medical research findings and their translation into clinical practice. Currently, we have 37 specialized sections open for manuscript submissions, which covers all topics related to clinical and pre-clinical practices.  Topics of interest include (but are not limited to) the following:

• Cardiology;
• Gastroenterology & Hepatopancreatobiliary Medicine;
• Clinical Neurology;
• Oncology;
• Orthopedics;
• Endocrinology & Metabolism;
• Nephrology & Urology;
• Epidemiology & Public Health;
• Stomatology;
• Pulmonology;
• Ophthalmology;
• Obstetrics & Gynecology;
• Immunology;
• Hematology;
• Clinical Psychology & Psychiatry;
• Otolaryngology;
• Dermatology;
• Clinical Pharmacology.

These 15 papers were selected and ranked by the JCM Editorial Office based on the average citation data of each paper since its publication. We hope that these high-quality research results will inspire our readers and provide a solid reference and strong support for future research in related fields.

We sincerely invite medical researchers in the field around the world to continue to pay attention to these cutting-edge results and work together to promote academic exchange and development in this field.

1. “The Prognostic Significance of Histological Subtypes in Patients with Muscle-Invasive Bladder Cancer: An Overview of the Current Literature”
by Francesco  Claps, Arianna Biasatti, Luca Di Gianfrancesco, Luca Ongaro, Gianluca Giannarini, Nicola Pavan, Antonio Amodeo, Alchiede Simonato, Alessandro Crestani, Alessia Cimadamore et al.
J. Clin. Med. 2024, 13(15), 4349; https://doi.org/10.3390/jcm13154349
Full text available online: https://www.mdpi.com/2077-0383/13/15/4349

2. “A Meta-Analysis of the Global Prevalence of Temporomandibular Disorders”
by Grzegorz  Zieliński, Beata Pająk-Zielińska and Michał Ginszt
J. Clin. Med. 2024, 13(5), 1365; https://doi.org/10.3390/jcm13051365
Full text available online: https://www.mdpi.com/2077-0383/13/5/1365

3. “Fecal Microbiota Transplantation: Insights into Colon Carcinogenesis and Immune Regulation”
by Olga  Brusnic, Danusia Onisor, Adrian Boicean, Adrian Hasegan, Cristian Ichim, Andreea Guzun, Radu Chicea, Samuel Bogdan Todor, Bogdan Ioan Vintila, Paula Anderco et al. 
J. Clin. Med. 2024, 13(21), 6578; https://doi.org/10.3390/jcm13216578
Full text available online: https://www.mdpi.com/2077-0383/13/21/6578

4. “Advanced Lung Cancer Inflammation Index as Predictor of All-Cause Mortality in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention”
by Giancarlo  Trimarchi, Fausto Pizzino, Alessio Lilli, Alberto Ranieri De Caterina, Augusto Esposito, Stefano Dalmiani, Annamaria Mazzone, Gianluca Di Bella, Sergio Berti and Umberto Paradossi
J. Clin. Med. 2024, 13(20), 6059; https://doi.org/10.3390/jcm13206059
Full text available online: https://www.mdpi.com/2077-0383/13/20/6059

5. “Global Prevalence of Sleep Bruxism and Awake Bruxism in Pediatric and Adult Populations: A Systematic Review and Meta-Analysis”
by Grzegorz  Zieliński, Agnieszka Pająk and Marcin Wójcicki
J. Clin. Med. 2024, 13(14), 4259; https://doi.org/10.3390/jcm13144259
Full text available online: https://www.mdpi.com/2077-0383/13/14/4259

6. “Clinical and Surgical Applications of Large Language Models: A Systematic Review”
by Sophia M. Pressman, Sahar Borna, Cesar A. Gomez-Cabello, Syed Ali Haider, Clifton R. Haider and Antonio Jorge Forte
J. Clin. Med. 2024, 13(11), 3041; https://doi.org/10.3390/jcm13113041
Full text available online: https://www.mdpi.com/2077-0383/13/11/3041

7. “The Brain–Gut Axis, an Important Player in Alzheimer and Parkinson Disease: A Narrative Review”
by Eugenio  Caradonna, Raffaello Nemni, Angelo Bifone, Patrizia Gandolfo, Lucy Costantino, Luca Giordano, Elisabetta Mormone, Anna Macula, Mariarosa Cuomo, Rossana Difruscolo et al. 
J. Clin. Med. 2024, 13(14), 4130; https://doi.org/10.3390/jcm13144130
Full text available online: https://www.mdpi.com/2077-0383/13/14/4130

8. “The Surgical Stress Response and Anesthesia: A Narrative Review”
by Robert  Ivascu, Ligia I. Torsin, Laura Hostiuc, Cornelia Nitipir, Dan Corneci and Madalina Dutu
J. Clin. Med. 2024, 13(10), 3017; https://doi.org/10.3390/jcm13103017
Full text available online: https://www.mdpi.com/2077-0383/13/10/3017

9. “The Effects of Obstructive Sleep Apnea on the Cardiovascular System: A Comprehensive Review”
by Michael V. DiCaro, KaChon Lei, Brianna Yee and Tahir Tak
J. Clin. Med. 2024, 13(11), 3223; https://doi.org/10.3390/jcm13113223
Full text available online: https://www.mdpi.com/2077-0383/13/11/3223

10. “A Non-Coronary, Peripheral Arterial Atherosclerotic Disease (Carotid, Renal, Lower Limb) in Elderly Patients—A Review: Part I—Epidemiology, Risk Factors, and Atherosclerosis-Related Diversities in Elderly Patients”
by Marcin  Piechocki,  Tadeusz Przewłocki, Piotr Pieniążek, Mariusz Trystuła, Jakub Podolec and Anna Kabłak-Ziembicka
J. Clin. Med. 2024, 13(5), 1471; https://doi.org/10.3390/jcm13051471
Full text available online: https://www.mdpi.com/2077-0383/13/5/1471

11. “Risk Factors of Chronic Kidney Disease Progression: Between Old and New Concepts”
by Francesca  Mallamaci and Giovanni Tripepi
J. Clin. Med. 2024, 13(3), 678; https://doi.org/10.3390/jcm13030678
Full text available online: https://www.mdpi.com/2077-0383/13/3/678

12. “Trichophyton indotineae, an Emerging Drug-Resistant Dermatophyte: A Review of the Treatment Options”
by Benedetta  Sonego, Andrea Corio, Vanessa Mazzoletti, Verena Zerbato, Alessandro Benini, Nicola di Meo, Iris Zalaudek, Giuseppe Stinco, Enzo Errichetti and Enrico Zelin
J. Clin. Med. 2024, 13(12), 3558; https://doi.org/10.3390/jcm13123558
Full text available online: https://www.mdpi.com/2077-0383/13/12/3558

13. “A Review of Intraocular Lens Power Calculation Formulas Based on Artificial Intelligence”
by Wiktor  Stopyra, David L. Cooke and Andrzej Grzybowski
J. Clin. Med. 2024, 13(2), 498; https://doi.org/10.3390/jcm13020498
Full text available online: https://www.mdpi.com/2077-0383/13/2/498

14. “Vitiligo: From Pathogenesis to Treatment”
by Reinhart  Speeckaert, Elise Van Caelenberg, Arno Belpaire, Marijn M. Speeckaert and Nanja van Geel.
J. Clin. Med. 2024, 13(17), 5225; https://doi.org/10.3390/jcm13175225
Full text available online: https://www.mdpi.com/2077-0383/13/17/5225

15. “The Transorbital Approach: A Comprehensive Review of Targets, Surgical Techniques, and Multiportal Variants”
by Matteo  De Simone, Cesare Zoia, Anis Choucha, Doo-Sik Kong and Lucio De Maria
J. Clin. Med. 2024, 13(9), 2712; https://doi.org/10.3390/jcm13092712
Full text available online: https://www.mdpi.com/2077-0383/13/9/2712

Conference: 28th EVER Congress
Date: 9–11 October 2025
Location: Florence, Italy

MDPI will be attending the 28th EVER Congress (EVER 2025) as an exhibitor, welcoming researchers from diverse backgrounds to visit and share their latest ideas.

EVER is the leading ophthalmological research association in Europe, which covers all areas of ophthalmology and the visual sciences. It can be considered as a bridge between basic scientists and clinical eye research of ophthalmology (including retina, glaucoma, cornea and ocular surface, oncology, pediatric ophthalmology, strabismus, neuro-ophthalmology, and lens disorders). It is mostly interested in translational research within all areas of ophthalmology and the visual sciences. This is being introduced during the congress annual meetings, where the best researchers and ophthalmology clinicians are present. It is essential for EVER that these congress meetings are attended by delegates from all over the world.

The following open access journals will be represented at the conference:

• Journal of Clinical Medicine;
• Medicina;
• Reports;
• Medical Sciences;
• Vision;
• Children;
• Diseases;
• Journal of Eye Movement Research.

If you will be attending this conference, please feel free to start a conversation with us. Our delegates look forward to meeting you in person and answering any questions that you may have. For more information about the conference, please visit https://evercongress.org/.

MDPI will be attending the GSA 2025 Annual Scientific Meeting (GSA 2025), which will be held from 12 to 15 November 2025 in Boston, the USA. 

The Gerontological Society of America (GSA) is the oldest and largest interdisciplinary organization dedicated to research, education, and practice in the field of aging. The GSA’s principal mission, shared by its 6,000+ members in more than 50 countries, is to promote the study of aging and disseminate information to scientists, decision-makers, and the general public. Founded in 1945, the GSA is pivotal in advancing innovation in the study of aging domestically and internationally. It garners approximately 4,500 professionals from across the world for its Annual Scientific Meeting, which features over 500 sessions, and it additionally publishes leading peer-reviewed journals in this research area. 

The following open access journals will be represented at this conference:

• Healthcare;
• IJERPH;
• Societies;
• EJIHPE;
• JCDD;
• JCM;
• Nutrients;
• Epidemiologia;
• Behavioral Sciences;
• JAL. 

If you are planning to attend this event, please feel free to visit our booth and speak to our representatives. We look forward to meeting you in person and will assist you with any queries that you may have. 

Journal of Clinical Medicine (JCM, ISSN: 2077-0383) is an open access and semimonthly journal published online by MDPI. Manuscripts are peer-reviewed, and a first decision is provided to authors approximately 17.7 days after submission; acceptance to publication is undertaken in 2.7 days (median values for papers published in this journal in the first half of 2025). We sincerely thank the members of our Editorial Board and our reviewers, whose meticulous review and rigorous quality control processes ensure the exceptional quality of our publications. For each issue, we have selected one article as the Issue Cover. In the first half of 2025, we have 12 articles we would like to share. These selected works cover multiple directions within the journal's scope and are dedicated to providing researchers in related disciplines with both valuable inspirational insights and reliable academic references.

In addition, you can explore more new research via this link: https://www.mdpi.com/search?q=&journal=jcm&sort=pubdate&page_count=50.

	1. “Preclinical Identification of Poorly Controlled COPD: Patients with a Single Moderate Exacerbation Matter Too” by José David Maya Viejo and Fernando M. Navarro Ros J. Clin. Med.2025, 14(1), 22; https://doi.org/10.3390/jcm14010022 Available online: https://www.mdpi.com/2077-0383/14/1/22
	2. “Restoration of Genuine Sensation and Proprioception of Individual Fingers Following Transradial Amputation with Targeted Sensory Reinnervation as a Mechanoneural Interface” by Alexander Gardetto, Gernot R. Müller-Putz, Kyle R. Eberlin, Franco Bassetto, Diane J. Atkins, Mara Turri, Gerfried Peternell, Ortrun Neuper and Jennifer Ernst J. Clin. Med.2025, 14(2), 417; https://doi.org/10.3390/jcm14020417 Available online: https://www.mdpi.com/2077-0383/14/2/417
	3. “Five-Year Comparative Study of Zygomatic and Subperiosteal Implants: Clinical Outcomes, Complications, and Treatment Strategies for Severe Maxillary Atrophy” by Rafal Zielinski, Jakub Okulski, Martyna Piechaczek, Jan Łoś, Jerzy Sowiński, Monika Sadowska-Sowińska, Agata Kołkowska, Wojciech Simka and Marcin Kozakiewicz J. Clin. Med.2025, 14(3), 661; https://doi.org/10.3390/jcm14030661 Available online: https://www.mdpi.com/2077-0383/14/3/661
	4. “Polyamine Inhibition with DFMO: Shifting the Paradigm in Neuroblastoma Therapy” by Joseph Schramm, Chloe Sholler, Leah Menachery, Laura Vazquez and Giselle Saulnier Sholler J. Clin. Med.2025, 14(4), 1068; https://doi.org/10.3390/jcm14041068 Available online: https://www.mdpi.com/2077-0383/14/4/1068
	5. “Multi-Directional Crosswalk of the Harris Hip Score and the Hip Disability and Osteoarthritis Outcome Score” by Chan Hee Cho, Kerry Costi, Deepti Sharma, Dominic Thewlis, Lucian B. Solomon and Stuart A. Callary J. Clin. Med.2025, 14(5), 1432; https://doi.org/10.3390/jcm14051432 Available online: https://www.mdpi.com/2077-0383/14/5/1432
	6. “Bone Regeneration: A Review of Current Treatment Strategies” by Raffaella De Pace, Silvia Molinari, Elisa Mazzoni and Giuseppe Perale J. Clin. Med.2025, 14(6), 1838;  https://doi.org/10.3390/jcm14061838 Available online: https://www.mdpi.com/2077-0383/14/6/1838
	7. “Advances and New Therapies in Traumatic Spinal Cord Injury” by Antonio Montoto-Marqués, Jesús Benito-Penalva, María Elena Ferreiro-Velasco, Mark Andrew Wright, Sebastian Salvador-De la Barrera, Hatice Kumru, Nelson Gaitán-Pérez, Agustin Hernández-Navarro, Antonio Rodríguez-Sotillo and Fernando Martins Braga et al. J. Clin. Med.2025, 14(7), 2203; https://doi.org/10.3390/jcm14072203 Available online: https://www.mdpi.com/2077-0383/14/7/2203
	8. “Advances in Current Treatment Paradigms for Metastatic Hormone-Sensitive Prostate Cancer” by Shayan Smani, Julien DuBois, Ismail Ajjawi, Nishan Sohoni, Ankur U. Choksi, Soum D. Lokeshwar, Isaac Y. Kim and Joseph F. Renzulli II J. Clin. Med.2025, 14(8), 2565; https://doi.org/10.3390/jcm14082565 Available online: https://www.mdpi.com/2077-0383/14/8/2565
	9. “A Pragmatic Approach to Acute Cardiorenal Syndrome: Diagnostic Strategies and Targeted Therapies to Overcome Diuretic Resistance” by Patrick Tran, Laith Khweir, Michael Kuehl, Mithilesh Joshi, Krishna Appunu, Waqar Ayub and Prithwish Banerjee J. Clin. Med.2025, 14(9), 2996; https://doi.org/10.3390/jcm14092996 Available online: https://www.mdpi.com/2077-0383/14/9/2996
	10. “Large Language Models in Cancer Imaging: Applications and Future Perspectives” by Mickael Tordjman, Ian Bolger, Murat Yuce, Francisco Restrepo, Zelong Liu, Laurent Dercle, Jeremy McGale, Anis L. Meribout, Mira M. Liu and Arnaud Beddok et al. J. Clin. Med.2025, 14(10), 3285; https://doi.org/10.3390/jcm14103285 Available online: https://www.mdpi.com/2077-0383/14/10/3285
	11. “Cardiac Edema Is Associated with White Matter Hyperintensities in Patients with Inflammatory Arthritides: A Combined Brain/Heart MRI Study” by George Markousis-Mavrogenis, Aliki Venetsanopoulou, Ioannis Ntalas, Ioannis Pagounis, Christina Naka, Dionisis Toliopoulos, Dimitrios Apostolou, Paraskevi Voulgari and Sophie I. Mavrogeni J. Clin. Med.2025, 14(11), 3726; https://doi.org/10.3390/jcm14113726 Available online: https://www.mdpi.com/2077-0383/14/11/3726
	12. “Sodium Oxybate (SMO) as Part of Agonist Opioid Treatment in Alcohol–Heroin-Addicted Patients” by Angelo G. I. Maremmani, Filippo Della Rocca, Matteo Pacini, Silvia Bacciardi, Silvia Cimino, Luca Cerniglia, Mario Miccoliand and Icro Maremmani J. Clin. Med. 2025, 14(12), 4016; https://doi.org/10.3390/jcm14124016 Available online: https://www.mdpi.com/2077-0383/14/12/4016

MDPI will be attending the 84th Annual Meeting of the Japanese Cancer Association from 25 to 27 September 2025 in Kanazawa City, Ishikawa Prefecture, Japan. We welcome researchers from diverse backgrounds to visit our booth and share their latest ideas with us.

The Annual Meeting is a major event regularly organized by the Japanese Cancer Association to disseminate the latest achievements in cancer research. The 84th Annual Meeting, held under the theme “Believe in the power of cancer research”, emphasizes innovative basic research to deepen our understanding of cancer biology and drive the development of new therapeutic strategies. A total of 20 symposia will be held, each focusing on a specific, cutting-edge research topic, and special lectures will be presented by world-leading cancer researchers. The conference will provide participants with the opportunity to engage with the forefront of international research.

The following MDPI journals will be represented:

• Cancers;
• Journal of Clinical Medicine;
• Diseases;
• Current Oncology;
• Clinics and Practice;
• Medical Sciences;
• Onco;
• Radiation.

We welcome you to visit the MDPI booth (#J-2) at the Hotel Nikko Kanazawa. Our representatives are excited to meet you in person and address any questions you may have. For further details about the conference, please visit the following website: https://www.c-linkage.co.jp/jca2025/en/.

Journal of Clinical Medicine (JCM, ISSN: 2077-0383) held its Editorial Board meeting for the Section “Orthopedics”, which was hosted by the Section Editor-in-Chief, Dr. Nicholas David Clement. Four Editorial Board Members were in attendance on 24 June 2025. We sincerely hope that more Members can join future meetings. We would like to invite you to review the contents of the meeting.

The meeting started with a presentation about the development of the journal, as well as the Section “Orthopedics” in particular, and the following information was presented:

• Journal history and open access policy;
• Publication statistics and authors group analysis (2018–2024);
• Journal awards, conference sponsorship, and journal social media management;
• Section development statistics, decision-making statistics, active Members, and the Section’s highly cited papers. 

The following topics were covered in the discussion at this Editorial Board meeting:

• Members recognized the growth of the orthopedics section and agreed to continue strengthening cooperation with authoritative authors, focusing on publishing high-quality papers, and striving to build the journal into a high-level platform for enhancing professional expertise;
• We need to continue taking measures to mobilize academic resources and expand the influence of the journal. We will collaborate with scientific associations and professional societies to accurately meet the needs of doctors and researchers. We will pay close attention to the discussions at important international orthopedic conferences and provide a publishing platform for high-quality seminar results, enabling the latest clinical experiences and research developments to be disseminated more quickly;
• Focusing on hot topics from international conferences, we will create Special Issues on related themes. Each Special Issue should have a clearer focus, and members should provide practical suggestions for soliciting high-quality manuscripts;
• Strengthening the development of the member team, increasing members' participation, and calling on more members to participate in daily journal activities.

Attendee list (in no particular order):

• Dr. Nicholas David Clement (Section Editor-in-Chief), Edinburgh Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, UK;
• Dr. Christian Carulli, Orthopaedic Clinic, University of Florence, Florence, Italy;
• Dr. Julien Favre, Lausanne University Hospital and University of Lausanne (CHUV-UNIL), Lausanne, Switzerland;
• Prof. Dr. Mattia Loppini, ¹ Department of Biomedical Sciences, Humanitas University, Milan, Italy; ² IRCCS Humanitas Research Hospital, Milan, Italy;
• Prof. Dr. Ross K. Leighton, Department of Orthopaedics, Dalhousie University, Halifax, NS, Canada.

To access more information about the “Orthopedics” Section, please visit the following link:
https://www.mdpi.com/journal/jcm/sections/Orthopedics.

In addition, we welcome submissions of Special Issue Proposals. For more information, please refer to the following link: https://www.mdpi.com/journalproposal/sendproposalspecialissue/jcm.

JCM Editorial Office

On 27 August 2025, MDPI and Journal of Clinical Medicine (JCMI, ISSN: 2077-0383)  will host a webinar entitled “Interventional Radiology: From Diagnosis to Treatment”. This webinar is open to all those who are interested in interventional radiology and will explore the most recent advances in the diagnosis and treatment of various diseases, with a focus on the lung and liver.

Date: 27 August 2025
Time: 7:00 p.m. CEST | 1:00 p.m. EDT
Webinar ID: 849 7438 7433

Register now for free!

After registering, you will receive a confirmation email containing information on how to join the webinar. Registrations with academic or institutional email addresses will be prioritized. 

If you are unable to attend, please feel free to register nonetheless; we will inform you once a recording of the webinar becomes available.

Webinar Chair and Speakers:

• Prof. Dr. Thomas J. Vogl, Clinic for Radiology and Nuclear Medicine, University Hospital Frankfurt, Goethe University, Theodor-Stern-Kai 7, 60590, Frankfurt Am Main, Germany;
• Dr. Hamzah Adwan, Clinic for Radiology and Nuclear Medicine, University Hospital Frankfurt, Goethe University, Theodor-Stern-Kai 7, 60590, Frankfurt Am Main, Germany;
• Prof. Dr. Tatjana Gruber-Rouh, Clinic for Radiology and Nuclear Medicine, University Hospital Frankfurt, Goethe University, Theodor-Stern-Kai 7, 60590, Frankfurt Am Main, Germany.

Relevant Special Issue:
“Current Advances in Interventional Oncology”
Guest Editor: Prof. Dr. Thomas Vogl
Deadline for manuscript submission: 25 September 2025

For more information about this webinar, please visit the following link: https://sciforum.net/event/JCM-17 .

If you have any questions about this webinar, please contact journal.webinar@mdpi.com.

JCM Webinar Secretariat

We are pleased to introduce the highly cited papers and hot Special Issues in the “Emergency Medicine” Section of Journal of Clinical Medicine (JCM, ISSN: 2077-0383).  Our “Emergency Medicine” Section’s goal is to improve the quality of care by publishing high-quality research for emergency medicine and related specialties by publishing original research related to the practice and research of emergency medicine. The subject areas include, but are not limited to, the following:

• Triage;
• Disposition;
• Risk-stratification;
• General emergency medicine;
• Acute pain;
• Out-of-hospital emergency medical services;
• Pediatric emergency medicine;
• Geriatric emergency medicine;
• Emerging new diseases;
• Injury and disease prevention.

For more details about this section and to access the latest publications, please visit: https://www.mdpi.com/journal/jcm/sections/Emergency_Med.

1. “Acute Lung Injury after Cardiopulmonary Resuscitation: A Narrative Review”
by Giuseppe Marchese, Elisabetta Bungaro, Aurora Magliocca, Francesca Fumagalli, Giulia Merigo, Federico Semeraro, Elisa Mereto, Giovanni Babini, Erik Roman-Pognuz, Giuseppe Stirparo et al.
J. Clin. Med. 2024, 13(9), 2498; https://doi.org/10.3390/jcm13092498
Full text available online: https://www.mdpi.com/2077-0383/13/9/2498

2. “Pulmonary Embolism in Pregnancy: A Review for Clinical Practitioners”
by Agata  Makowska, Thomas Treumann, Stefan Venturini and Michael Christ
J. Clin. Med. 2024, 13(10), 2863; https://doi.org/10.3390/jcm13102863
Full text available online: https://www.mdpi.com/2077-0383/13/10/2863

3. “Improved Extracorporeal Cardiopulmonary Resuscitation (ECPR) Outcomes are Associated with a Restrictive Patient Selection Algorithm”
by Benjamin Assouline, Nathalie Mentha, Hannah Wozniak, Viviane Donner, Carole Looyens, Laurent Suppan, Robert Larribau, Carlo Banfi, Karim Bendjelid and Raphaël Giraud
J. Clin. Med. 2024, 13(2), 497; https://doi.org/10.3390/jcm13020497
Full text available online: https://www.mdpi.com/2077-0383/13/2/497

4. “The Use of Thrombectomy during Primary Percutaneous Coronary Intervention: Resurrecting an Old Concept in Contemporary Practice”
by Zahir Satti, Muntaser Omari, Bilal Bawamia, Timothy Cartlidge, Mohaned Egred, Mohamed Farag and Mohammad Alkhalil
J. Clin. Med. 2024, 13(8), 2291; https://doi.org/10.3390/jcm13082291
Full text available online: https://www.mdpi.com/2077-0383/13/8/2291

5. “Traumatic Brain Injury in Patients under Anticoagulant Therapy: Review of Management in Emergency Department”
by Vincenzo G. Menditto, Giulia Rossetti, Mattia Sampaolesi, Marta Buzzo and Giovanni Pomponio
J. Clin. Med. 2024, 13(13), 3669; https://doi.org/10.3390/jcm13133669
Full text available online: https://www.mdpi.com/2077-0383/13/13/3669

6. “Evaluation of New Cardiac Damage Biomarkers in Polytrauma: GDF-15, HFABP and uPAR for Predicting Patient Outcomes”
by Aileen Ritter, Lorenz Lötterle, Jiaoyan Han, Miriam Kalbitz, Dirk Henrich, Ingo Marzi, Liudmila Leppik and Birte Weber
J. Clin. Med. 2024, 13(4), 961; https://doi.org/10.3390/jcm13040961
Full text available online: https://www.mdpi.com/2077-0383/13/4/961

7. “Cardiac Arrest Mortality and Disposition Patterns in United States Emergency Departments”
by Kenneth M. Zabel, Mohammed A. Quazi, Katarina Leyba, Alexandra C. Millhuff, Mikel Madi, Wilfredo Henriquez Madrid, Aman Goyal, Muhammad Ibraiz Bilal, Amir H. Sohail, Shazib Sagheer et al.
J. Clin. Med. 2024, 13(18), 5585; https://doi.org/10.3390/jcm13185585
Full text available online: https://www.mdpi.com/2077-0383/13/18/5585

8. “Evolution of Cardiogenic Shock Management and Development of a Multidisciplinary Team-Based Approach: Ten Years Experience of a Single Center”
by Leonardo Belfioretti, Matteo Francioni, Ilaria Battistoni, Luca Angelini, Maria Vittoria Matassini, Giulia Pongetti, Matilda Shkoza, Luca Piangerelli, Tommaso Piva, Elisa Nicolini et al.
J. Clin. Med. 2024, 13(7), 2101; https://doi.org/10.3390/jcm13072101
Full text available online: https://www.mdpi.com/2077-0383/13/7/2101

9. “Vasopressor Therapy”
by Jean-Louis Vincent and Filippo Annoni
J. Clin. Med. 2024, 13(23), 7372; https://doi.org/10.3390/jcm13237372
Full text available online: https://www.mdpi.com/2077-0383/13/23/7372

10. “The Multidisciplinary Mobile Unit (MMU) Program Bringing Hospital Specialist Geriatric Competencies at Home: A Feasible Alternative to Admission in Older Patients with Urgent Complaints”
by Antonio Nouvenne, Andrea Ticinesi, Carmine Siniscalchi, Martina Rendo, Nicoletta Cerundolo, Alberto Parise, Giampiero Castaldo, Giulia Chiussi, Richard Carrassi, Angela Guerra et al.
J. Clin. Med. 2024, 13(9), 2720; https://doi.org/10.3390/jcm13092720
Full text available online: https://www.mdpi.com/2077-0383/13/9/2720

Special Issues:
“Cardiopulmonary Resuscitation—from Research to Clinical Implementation” Guest Editor: Prof. Dr. Endre Zima Submission deadline: 20 November 2025	“Recent Advances in Therapy of Trauma and Surgical Critical Care ” Guest Editor: Dr. Rita Galeiras Submission deadline: 20 December 2025
“New Advances in Extracorporeal Membrane Oxygenation (ECMO) ” Guest Editor: Dr. Camilla L’Acqua Submission deadline: 20 December 2025	“New Insights in Trauma and Emergency Surgery” Guest Editors: Dr. Kai Oliver Jensen and Prof. Dr. Valentin Neuhaus Submission deadline: 20 February 2026

Stroke is an acute nervous system disease caused by a variety of factors, such as cerebral vascular damage and focal or whole brain damage, and it has become a threat to global health. At present, medical research is deeply involved in the fields of early detection and timely intervention of stroke, prognosis management, and rehabilitation intervention, which injects new impetus into helping patients recover their functions, reduce recurrence, and improve their quality of life. We welcome you to read the following highly cited papers published in the Journal of Clinical Medicine (JCM, ISSN: 2077-0383), and hope that these articles can bring new ideas for stroke research. In addition, some Special Issues on this topic are currently open for submission.

1. “The Impact of Anti-Amyloid Immunotherapies on Stroke Care”
by Philippe A. Bilodeau, John R. Dickson and Mariel G. Kozberg
J. Clin. Med. 2024, 13(5), 1245; https://doi.org/10.3390/jcm13051245
Full text available online: https://www.mdpi.com/2077-0383/13/5/1245

2. “Sex-Related Differences in Mortality, Delayed Cerebral Ischemia, and Functional Outcomes in Patients with Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis”
by Sarah Berli, Massimo Barbagallo, Emanuela Keller, Giuseppe Esposito, Alberto Pagnamenta and Giovanna Brandi
J. Clin. Med. 2024, 13(10), 2781; https://doi.org/10.3390/jcm13102781
Full text available online: https://www.mdpi.com/2077-0383/13/10/2781

3. “Benefits of Robot-Assisted Upper-Limb Rehabilitation from the Subacute Stage after a Stroke of Varying Severity: A Multicenter Randomized Controlled Trial”
by So Young Ahn, Soo-Kyung Bok, Ji Young Lee, Hyeon Woo Ryoo, Hoo Young Lee, Hye Jung Park, Hyun Mi Oh and Tae-Woo Kim
J. Clin. Med. 2024, 13(3), 808; https://doi.org/10.3390/jcm13030808
Full text available online: https://www.mdpi.com/2077-0383/13/3/808

4. “Blood Pressure Variability in Acute Stroke: A Narrative Review”
by Christina Zompola, Lina Palaiodimou, Konstantinos Voumvourakis, Leonidas Stefanis, Aristeidis H. Katsanos, Else C. Sandset, Estathios Boviatsis and Georgios Tsivgoulis
J. Clin. Med. 2024, 13(7), 1981; https://doi.org/10.3390/jcm13071981
Full text available online: https://www.mdpi.com/2077-0383/13/7/1981

5. “Effectiveness of Virtual Reality in Occupational Therapy for Post-Stroke Adults: A Systematic Review”
by Síbila Floriano Landim, Roberto López, Antonia Caris, Constanza Castro, Ramon D. Castillo, Daniela Avello, Braulio Henrique Magnani Branco, Pablo Valdés-Badilla, Florencia Carmine, Cristian Sandoval et al.
J. Clin. Med. 2024, 13(16), 4615; https://doi.org/10.3390/jcm13164615
Full text available online: https://www.mdpi.com/2077-0383/13/16/4615

6. “Flow Diversion for Endovascular Treatment of Intracranial Aneurysms: Past, Present, and Future Directions”
by Michael Gaub, Greg Murtha, Molly Lafuente, Matthew Webb, Anqi Luo, Lee A. Birnbaum, Justin R. Mascitelli and Fadi Al Saiegh
J. Clin. Med. 2024, 13(14), 4167; https://doi.org/10.3390/jcm13144167
Full text available online: https://www.mdpi.com/2077-0383/13/14/4167

7. “A Long-Term Comparative Analysis of Endovascular Coiling and Clipping for Ruptured Cerebral Aneurysms: An Individual Patient-Level Meta-Analysis Assessing Rerupture Rates”
by Johannes Wach, Martin Vychopen, Agi Güresir, Alexandru Guranda, Ulf Nestler and Erdem Güresir
J. Clin. Med. 2024, 13(6), 1778; https://doi.org/10.3390/jcm13061778
Full text available online: https://www.mdpi.com/2077-0383/13/6/1778

8. “Influence of High-Intensity Interval Training on Neuroplasticity Markers in Post-Stroke Patients: Systematic Review”
by Gines Montero-Almagro, Carlos Bernal-Utrera, Noelia Geribaldi-Doldán, Pedro Nunez-Abades, Carmen Castro and Cleofas Rodriguez-Blanco
J. Clin. Med. 2024, 13(7), 1985; https://doi.org/10.3390/jcm13071985
Full text available online: https://www.mdpi.com/2077-0383/13/7/1985

9. “Stroke in Young Adults”
by Syed Bukhari, Shadi Yaghi and Zubair Bashir
J. Clin. Med. 2023, 12(15), 4999; https://doi.org/10.3390/jcm12154999
Full text available online: https://www.mdpi.com/2077-0383/12/15/4999

10. “Age Stratification and Stroke Severity in the Telestroke Network”
by Cassie A. Simmons, Nicolas Poupore and Thomas I. Nathaniel
J. Clin. Med. 2023, 12(4), 1519; https://doi.org/10.3390/jcm12041519
Full text available online: https://www.mdpi.com/2077-0383/12/4/1519

Special Issues:
“Recent Advances in Intracranial Aneurysm Treatment” Guest Editor: Dr. Victor Volovici Submission deadline: 25 November 2025	“Neurovascular Diseases: Clinical Advances and Challenges” Guest Editors: Dr. Roberto Colasanti; Dr. Silky Chotai; Dr. Alessandro Di Rienzo and Dr. Joham Choque-Velasquez Submission deadline: 25 November 2025
“Current Situation and Challenges of Endovascular Treatment Strategies for Acute Ischemic Stroke ” Guest Editor: Prof. Dr. Fusao Ikawa Submission deadline: 20 January 2026	“Revolutionizing Neurosurgery: Cutting-Edge Techniques and Innovations” Guest Editor: Dr. Yoichi Morofuji Submission deadline: 31 January 2026