You are currently on the new version of our website. Access the old version .

81 Results Found

  • Article
  • Open Access
1 Citations
1,903 Views
13 Pages

In this paper, we study the multi-objective optimization of the viscous boundary condition of an elastic rod using a hybrid method combining a genetic algorithm and simple cell mapping (GA-SCM). The method proceeds with the NSGAII algorithm to seek a...

  • Article
  • Open Access
407 Views
17 Pages

The design of a control system becomes more complex with the advancement of technology, and this requires optimization techniques to be developed. In particular, multi-objective optimal control (MOC) is a method that can be used to achieve a scheme f...

  • Article
  • Open Access
10 Citations
5,778 Views
18 Pages

This article examines the problems of multi-robot coverage and persistent monitoring of regions of interest with limited sensing robots. A group of robots, each equipped with only contact sensors and a clock, execute a simple trajectory by repeatedly...

  • Article
  • Open Access
12 Citations
3,180 Views
19 Pages

Using EMPHASIS for the Thermography-Based Fault Detection in Photovoltaic Plants

  • Antonio Pio Catalano,
  • Ciro Scognamillo,
  • Pierluigi Guerriero,
  • Santolo Daliento and
  • Vincenzo d’Alessandro

11 March 2021

In this paper, an Efficient Method for PHotovoltaic Arrays Study through Infrared Scanning (EMPHASIS) is presented; it is a fast, simple, and trustworthy cell-level diagnosis method for commercial photovoltaic (PV) panels. EMPHASIS processes temperat...

  • Review
  • Open Access
7 Citations
5,660 Views
11 Pages

The MAPPIT (mammalian protein protein interaction trap) method allows high-throughput detection of protein interactions by very simple co-transfection of three plasmids in HEK293T cells, followed by a luciferase readout. MAPPIT detects a large percen...

  • Article
  • Open Access
7 Citations
7,451 Views
11 Pages

Investigation of Reactant Conversion in the Vanadium Redox Flow Battery Using Spatially Resolved State of Charge Mapping

  • Purna C. Ghimire,
  • Arjun Bhattarai,
  • Rüdiger Schweiss,
  • Günther G. Scherer,
  • Nyunt Wai,
  • Tuti M. Lim and
  • Qingyu Yan

Segmented cells enable real time visualization of the flow distribution in vanadium redox flow batteries by local current or voltage mapping. The lateral flow of current within thick porous electrodes, however, impairs the local resolution of the det...

  • Article
  • Open Access
3 Citations
3,973 Views
12 Pages

Using the Thickness Map from Macular Ganglion Cell Analysis to Differentiate Retinal Vein Occlusion from Glaucoma

  • Nam Ho Lee,
  • Kee Sup Park,
  • Han Min Lee,
  • Jung Yeul Kim,
  • Chang-sik Kim and
  • Kyoung Nam Kim

14 October 2020

Purpose: We hypothesized that the thickness map from macular ganglion cell analysis (GCA) acquired from spectral-domain optical coherence tomography can be used to differentiate retinal vein occlusion (RVO) from glaucoma. Methods: In this retrospecti...

  • Article
  • Open Access
2,179 Views
10 Pages

20 December 2020

A three-dimensional profile reconstruction of live cells in dynamic cell cultures is a challenging problem due to the highly scattering nature of cell mediums. Furthermore, it is an interesting problem since these cultures present the optimal in vitr...

  • Article
  • Open Access
17 Citations
4,008 Views
18 Pages

15 February 2021

Semantic segmentation of room maps is an essential issue in mobile robots’ execution of tasks. In this work, a new approach to obtain the semantic labels of 2D lidar room maps by combining distance transform watershed-based pre-segmentation and a ski...

  • Article
  • Open Access
3 Citations
4,157 Views
11 Pages

A Method for Citizen Scientists to Catalogue Worldwide Chlorociboria spp. Distribution

  • Sarath M. Vega Gutierrez,
  • Olivia E. Kramer,
  • Claudia C. Andersen,
  • Patricia T. Vega Gutierrez and
  • Seri C. Robinson

The blue-green pigment known as xylindein that is produced by species in the Chlorociboria genus is under heavy investigation for its potential in textile dyes, wood dyes, and solar cells. Xylindein has not yet been synthesized, and while its product...

  • Article
  • Open Access
25 Citations
6,692 Views
29 Pages

10 August 2020

Estimating and mapping population distributions dynamically at a city-wide spatial scale, including those covering suburban areas, has profound, practical, applications such as urban and transportation planning, public safety warning, disaster impact...

  • Article
  • Open Access
21 Citations
6,761 Views
23 Pages

A Supervised Method for Nonlinear Hyperspectral Unmixing

  • Bikram Koirala,
  • Mahdi Khodadadzadeh,
  • Cecilia Contreras,
  • Zohreh Zahiri,
  • Richard Gloaguen and
  • Paul Scheunders

22 October 2019

Due to the complex interaction of light with the Earth’s surface, reflectance spectra can be described as highly nonlinear mixtures of the reflectances of the material constituents occurring in a given resolution cell of hyperspectral data. Our...

  • Article
  • Open Access
4 Citations
5,117 Views
19 Pages

20 June 2019

The success of hydrological modeling of a high mountain basin depends in most case on the accurate quantification of the snowmelt. However, mathematically modeling snowmelt is not a simple task due to, on one hand, the high number of variables that c...

  • Feature Paper
  • Article
  • Open Access
2,245 Views
12 Pages

CrossTx: Cross-Cell-Line Transcriptomic Signature Predictions

  • Panagiotis Chrysinas,
  • Changyou Chen and
  • Rudiyanto Gunawan

3 February 2024

Predicting the cell response to drugs is central to drug discovery, drug repurposing, and personalized medicine. To this end, large datasets of drug signatures have been curated, most notably the Connectivity Map (CMap). A multitude of in silico appr...

  • Article
  • Open Access
510 Views
15 Pages

It Is Simple to Program with Spiking Neurons

  • Christian Huyck and
  • Fayokunmi Obisesan

12 November 2025

Neural and synaptic models that are relatively biologically accurate are easy to use to run efficient and distributed programs. The mechanism described in this paper uses these models to develop cell assemblies with a small number of neurons that per...

  • Article
  • Open Access
43 Citations
5,336 Views
16 Pages

9 September 2018

Although autologous nerve grafting remains the gold standard treatment for peripheral nerve injuries, alternative methods such as development of nerve guidance conduits have since emerged and evolved to counter the many disadvantages of nerve graftin...

  • Feature Paper
  • Article
  • Open Access
20 Citations
7,677 Views
20 Pages

Disdyakis Triacontahedron DGGS

  • John Hall,
  • Lakin Wecker,
  • Benjamin Ulmer and
  • Faramarz Samavati

The amount of information collected about the Earth has become extremely large. With this information comes the demand for integration, processing, visualization and distribution of this data so that it can be leveraged to solve real-world problems....

  • Review
  • Open Access
36 Citations
10,399 Views
25 Pages

Current Status and Future Perspectives of Mass Spectrometry Imaging

  • Surendra Nimesh,
  • Susantha Mohottalage,
  • Renaud Vincent and
  • Prem Kumarathasan

28 May 2013

Mass spectrometry imaging is employed for mapping proteins, lipids and metabolites in biological tissues in a morphological context. Although initially developed as a tool for biomarker discovery by imaging the distribution of protein/peptide in tiss...

  • Article
  • Open Access
60 Citations
7,291 Views
14 Pages

Boron Nitride Doped Polyhydroxyalkanoate/Chitosan Nanocomposite for Antibacterial and Biological Applications

  • Abdul Mukheem,
  • Syed Shahabuddin,
  • Noor Akbar,
  • Azizi Miskon,
  • Norazilawati Muhamad Sarih,
  • Kumar Sudesh,
  • Naveed Ahmed Khan,
  • Rahman Saidur and
  • Nanthini Sridewi

21 April 2019

The present research focused on the fabrication of biocompatible polyhydroxyalkanoate, chitosan, and hexagonal boron nitride incorporated (PHA/Ch-hBN) nanocomposites through a simple solvent casting technique. The fabricated nanocomposites were compr...

  • Review
  • Open Access
56 Citations
7,833 Views
26 Pages

10 February 2021

Nonalcoholic fatty liver disease (NAFLD) is a rising chronic liver disease and comprises a spectrum from simple steatosis to nonalcoholic steatohepatitis (NASH) to end-stage cirrhosis and risk of hepatocellular carcinoma (HCC). The pathogenesis of NA...

  • Technical Note
  • Open Access
9 Citations
6,061 Views
16 Pages

Methods of In Situ Quantitative Root Biology

  • Taras Pasternak and
  • José Manuel Pérez-Pérez

6 November 2021

When dealing with plant roots, a multiscale description of the functional root structure is needed. Since the beginning of 21st century, new devices such as laser confocal microscopes have been accessible for coarse root structure measurements, inclu...

  • Article
  • Open Access
407 Views
16 Pages

Quantifying Early Electromechanical Integration of Cardiomyocytes Using a Minimalist PCL Nanofiber Platform

  • Vitalii Dzhabrailov,
  • Elena Turchaninova,
  • Daria V. Kononova,
  • Egor Ilin,
  • Mikhail Slotvitsky,
  • Anton Efimov,
  • Igor Agapov,
  • Valeriya Tsvelaya,
  • Alexander Romanov and
  • Konstantin Agladze

21 December 2025

A critical obstacle in cardiac cell therapy is the unpredictable and poorly understood initial electrophysiological integration of grafted cardiomyocytes into the host tissue, a process that dictates therapeutic success and arrhythmic risk. Current m...

  • Article
  • Open Access
17 Citations
9,522 Views
14 Pages

27 January 2016

Seagrass meadows, one of the most important habitats for many marine species, provide essential ecological services. Thus, society must conserve seagrass beds as part of their sustainable development efforts. Conserving these ecosystems requires info...

  • Article
  • Open Access
1 Citations
1,846 Views
14 Pages

Analysis of a Novel Method for Generating 3D Mesh at Contact Points in Packed Beds

  • Daniel F. Szambien,
  • Maximilian R. Ziegler,
  • Christoph Ulrich and
  • Roland Scharf

This study comprehensively analyzes the impact of the novel HybridBridge method, developed by the authors, for generating a 3D mesh at contact points within packed beds within the effective thermal conductivity. It compares HybridBridge with alternat...

  • Review
  • Open Access
7 Citations
6,818 Views
14 Pages

Modeling Red Blood Cell Metabolism in the Omics Era

  • Alicia Key,
  • Zachary Haiman,
  • Bernhard O. Palsson and
  • Angelo D’Alessandro

11 November 2023

Red blood cells (RBCs) are abundant (more than 80% of the total cells in the human body), yet relatively simple, as they lack nuclei and organelles, including mitochondria. Since the earliest days of biochemistry, the accessibility of blood and RBCs...

  • Article
  • Open Access
21 Citations
3,660 Views
19 Pages

Sn and Ge Complexes with Redox-Active Ligands as Efficient Interfacial Membrane-like Buffer Layers for p-i-n Perovskite Solar Cells

  • Azat F. Akbulatov,
  • Anna Y. Akyeva,
  • Pavel G. Shangin,
  • Nikita A. Emelianov,
  • Irina V. Krylova,
  • Mariya O. Markova,
  • Liliya D. Labutskaya,
  • Alexander V. Mumyatov,
  • Egor I. Tuzharov and
  • Pavel A. Troshin
  • + 4 authors

Inverted perovskite solar cells with a p-i-n configuration have attracted considerable attention from the research community because of their simple design, insignificant hysteresis, improved operational stability, and low-temperature fabrication tec...

  • Article
  • Open Access
1 Citations
2,657 Views
13 Pages

A Paratope-Enhanced Method to Determine Breadth and Depth TCR Clonal Metrics of the Private Human T-Cell Vaccine Response after SARS-CoV-2 Vaccination

  • Dalin Li,
  • Ana Jimena Pavlovitch-Bedzyk,
  • Joseph E. Ebinger,
  • Abdul Khan,
  • Mohamed Hamideh,
  • Akil Merchant,
  • Jane C. Figueiredo,
  • Susan Cheng,
  • Mark M. Davis and
  • Jonathan Braun
  • + 3 authors

18 September 2023

Quantitative metrics for vaccine-induced T-cell responses are an important need for developing correlates of protection and their use in vaccine-based medical management and population health. Molecular TCR analysis is an appealing strategy but curre...

  • Article
  • Open Access
28 Citations
5,758 Views
10 Pages

Analysis of Thematic Similarity Using Confusion Matrices

  • José L. García-Balboa,
  • María V. Alba-Fernández,
  • Francisco J. Ariza-López and
  • José Rodríguez-Avi

The confusion matrix is the standard way to report on the thematic accuracy of geographic data (spatial databases, topographic maps, thematic maps, classified images, remote sensing products, etc.). Two widely adopted indices for the assessment of th...

  • Article
  • Open Access
13 Citations
3,720 Views
17 Pages

Development of Neuropeptide Y and Cell-Penetrating Peptide MAP Adsorbed onto Lipid Nanoparticle Surface

  • Sara Silva,
  • Joana Marto,
  • Lídia M. Gonçalves,
  • Henrique S. Fernandes,
  • Sérgio F. Sousa,
  • António J. Almeida and
  • Nuno Vale

24 April 2022

Functionalization of nanoparticles surfaces have been widely used to improve diagnostic and therapeutic biological outcome. Several methods can be applied to modify nanoparticle surface; however, in this article we focus toward a simple and less time...

  • Feature Paper
  • Article
  • Open Access
10 Citations
4,987 Views
12 Pages

Low-Temperature Crystal Structures of the Hard Core Square Shoulder Model

  • Alexander Gabriëlse,
  • Hartmut Löwen and
  • Frank Smallenburg

7 November 2017

In many cases, the stability of complex structures in colloidal systems is enhanced by a competition between different length scales. Inspired by recent experiments on nanoparticles coated with polymers, we use Monte Carlo simulations to explore the...

  • Article
  • Open Access
2 Citations
1,642 Views
19 Pages

18 October 2023

Algal cell abundance weakly depends on inherent optical properties and chlorophyll-a concentration in the Bohai Sea, so it is very hard to derive algal cell abundance (ACA) from ocean color data using a simple bio-optical model. To obtain ACA for bio...

  • Article
  • Open Access
7 Citations
3,570 Views
14 Pages

With the development of lithium-ion batteries and fuel cells, the application of hybrid power systems is becoming more and more widespread. To better optimize the energy management problem of fuel cell hybrid systems, the accuracy of system modeling...

  • Review
  • Open Access
15 Citations
6,428 Views
29 Pages

Patient-Derived Multiple Myeloma 3D Models for Personalized Medicine—Are We There Yet?

  • Diana Lourenço,
  • Raquel Lopes,
  • Carolina Pestana,
  • Ana C. Queirós,
  • Cristina João and
  • Emilie Arnault Carneiro

25 October 2022

Despite the wide variety of existing therapies, multiple myeloma (MM) remains a disease with dismal prognosis. Choosing the right treatment for each patient remains one of the major challenges. A new approach being explored is the use of ex vivo mode...

  • Article
  • Open Access
993 Views
14 Pages

A Benchmark for Symbolic Reasoning from Pixel Sequences: Grid-Level Visual Completion and Correction

  • Lei Kang,
  • Xuanshuo Fu,
  • Mohamed Ali Souibgui,
  • Andrey Barsky,
  • Lluis Gomez,
  • Javier Vazquez-Corral,
  • Alicia Fornés,
  • Ernest Valveny and
  • Dimosthenis Karatzas

4 September 2025

Grid structured visual data such as forms, tables, and game boards require models that pair pixel level perception with symbolic consistency under global constraints. Recent Pixel Language Models (PLMs) map images to token sequences with promising fl...

  • Article
  • Open Access
6 Citations
5,473 Views
14 Pages

21 November 2018

We apply hierarchical clustering (HC) of DNA k-mer counts on multiple Fastq files. The tree structures produced by HC may reflect experimental groups and thereby indicate experimental effects, but clustering of preparation groups indicates the presen...

  • Article
  • Open Access
8 Citations
5,369 Views
23 Pages

Mapping the Melanoma Plasma Proteome (MPP) Using Single-Shot Proteomics Interfaced with the WiMT Database

  • Natália Almeida,
  • Jimmy Rodriguez,
  • Indira Pla Parada,
  • Yasset Perez-Riverol,
  • Nicole Woldmar,
  • Yonghyo Kim,
  • Henriett Oskolas,
  • Lazaro Betancourt,
  • Jeovanis Gil Valdés and
  • Aniel Sanchez
  • + 9 authors

10 December 2021

Plasma analysis by mass spectrometry-based proteomics remains a challenge due to its large dynamic range of 10 orders in magnitude. We created a methodology for protein identification known as Wise MS Transfer (WiMT). Melanoma plasma samples from bio...

  • Article
  • Open Access
5 Citations
2,459 Views
23 Pages

Due to their high efficiency and advanced battery management capability, cascaded multilevel inverters are an exciting option for battery electric powertrains. A promising, new and highly efficient cascaded multilevel inverter is the Parallel Enhance...

  • Article
  • Open Access
9 Citations
3,520 Views
16 Pages

17 December 2022

The prediction of thermal behavior is essential for an efficient initial design of thermal management systems which equip energy sources based on electrochemical cells. In this study, the surface temperature of various cylindrical types of Li-ion bat...

  • Article
  • Open Access
23 Citations
5,472 Views
23 Pages

14 February 2023

Multi-robot exploration means constructing a finite map using a group of robots in an obstacle chaotic space. Uncertainties are reduced by distributing search tasks to robots and computing the best action in real time. Many previous methods are based...

  • Article
  • Open Access
13 Citations
3,993 Views
12 Pages

Designing Functionally Versatile, Highly Immunogenic Peptide-Based Multiepitopic Vaccines against Foot-and-Mouth Disease Virus

  • Sira Defaus,
  • Mar Forner,
  • Rodrigo Cañas-Arranz,
  • Patricia de León,
  • María J. Bustos,
  • Miguel Rodríguez-Pulido,
  • Esther Blanco,
  • Francisco Sobrino and
  • David Andreu

A broadly protective and biosafe vaccine against foot-and-mouth disease virus (FMDV) remains an unmet need in the animal health sector. We have previously reported solid protection against serotype O FMDV afforded by dendrimeric peptide structures ha...

  • Article
  • Open Access
58 Citations
3,625 Views
10 Pages

Design of a Structure for Optimized Optical Performance of a Full Colored Organic Light-Emitting Diode on a Parameter Space Map

  • Chang-Hee Lee,
  • Ju-Hyeok Choi,
  • Seo-Yong Hyun,
  • Ji-Ho Baek,
  • Bongsoon Kang and
  • Gi-Dong Lee

31 January 2022

In general, optical properties of a top-emitting organic light-emitting diode (OLED) are dependent on the cavity effect of the OLED structure. Therefore, the optical path length of the many thin solid films in the OLED, which is strongly affected by...

  • Review
  • Open Access
25 Citations
5,239 Views
31 Pages

The Fission Yeast Cell Integrity Pathway: A Functional Hub for Cell Survival upon Stress and Beyond

  • José Cansado,
  • Teresa Soto,
  • Alejandro Franco,
  • Jero Vicente-Soler and
  • Marisa Madrid

30 December 2021

The survival of eukaryotic organisms during environmental changes is largely dependent on the adaptive responses elicited by signal transduction cascades, including those regulated by the Mitogen-Activated Protein Kinase (MAPK) pathways. The Cell Int...

  • Article
  • Open Access
17 Citations
3,106 Views
13 Pages

Optimisation Study of Co Deposition on Chars from MAP of Waste Tyres as Green Electrodes in ORR for Alkaline Fuel Cells

  • Maurizio Passaponti,
  • Leonardo Lari,
  • Marco Bonechi,
  • Francesca Bruni,
  • Walter Giurlani,
  • Gabriele Sciortino,
  • Luca Rosi,
  • Lorenzo Fabbri,
  • Martina Vizza and
  • Massimo Innocenti
  • + 2 authors

28 October 2020

Oxygen Reduction Reaction (ORR) catalysts, from waste automobile tyres obtained from Microwave assisted pyrolysis (MAP), were enriched with Co and Cu using the simple treatments sonochemical and electrochemical deposition. Catalytic activity was eval...

  • Article
  • Open Access
7 Citations
3,241 Views
11 Pages

Mechanistic Association of Quantitative Trait Locus with Malate Secretion in Lentil (Lens culinaris Medikus) Seedlings under Aluminium Stress

  • Chandan Kumar Singh,
  • Dharmendra Singh,
  • Shristi Sharma,
  • Shivani Chandra,
  • Ram Sewak Singh Tomar,
  • Arun Kumar,
  • K. C. Upadhyaya and
  • Madan Pal

28 July 2021

Aluminium (Al) toxicity acts as a major delimiting factor in the productivity of many crops including lentil. To alleviate its effect, plants have evolved with Al exclusion and inclusion mechanisms. The former involves the exudation of organic acid t...

  • Article
  • Open Access
10 Citations
3,978 Views
32 Pages

30 June 2021

In the current study, a simple in silico approach using free software was used with the experimental studies to optimize the antiproliferative activity and predict the potential mechanism of action of pyrrolizine-based Schiff bases. A compound librar...

  • Article
  • Open Access
468 Views
13 Pages

1 December 2025

We previously developed a bead-coupled ligase detection reaction (LDR) assay that enables simple and rapid detection of single-nucleotide variations (SNVs) using synthetic oligonucleotide templates. In the present study, this approach was extended to...

  • Article
  • Open Access
11,755 Views
10 Pages

4 November 2022

Equivalent circuit models of solar cells are important for understanding the behavior of photovoltaic systems under different weather conditions. They provide an equation F(V,I)=0 that expresses the correspondence between voltage V and current I a ce...

  • Article
  • Open Access
13 Citations
4,010 Views
20 Pages

Molecular Recognition of Surface Trans-Sialidases in Extracellular Vesicles of the Parasite Trypanosoma cruzi Using Atomic Force Microscopy (AFM)

  • Alexa Prescilla-Ledezma,
  • Fátima Linares,
  • Mariano Ortega-Muñoz,
  • Lissette Retana Moreira,
  • Ana Belén Jódar-Reyes,
  • Fernando Hernandez-Mateo,
  • Francisco Santoyo-Gonzalez and
  • Antonio Osuna

Trans-sialidases (TS) are important constitutive macromolecules of the secretome present on the surface of Trypanosoma cruzi (T. cruzi) that play a central role as a virulence factor in Chagas disease. These enzymes have been related to infectivity,...

  • Feature Paper
  • Article
  • Open Access
27 Citations
14,358 Views
23 Pages

Li-ion Electrode Microstructure Evolution during Drying and Calendering

  • Mojdeh Nikpour,
  • Baichuan Liu,
  • Paul Minson,
  • Zachary Hillman,
  • Brian A. Mazzeo and
  • Dean R. Wheeler

1 September 2022

The drying process of electrodes might seem to be a simple operation, but it has profound effects on the microstructure. Some unexpected changes can happen depending on the drying conditions. In prior work, we developed the multiphase-smoothed-partic...

  • Article
  • Open Access
2 Citations
2,455 Views
16 Pages

High-Resolution Ultrasound Platform for Infant Meningitis Detection: An In Vitro Demonstration

  • Manuel Navarrete,
  • David Castells-Rufas,
  • Hassane Baghdad Kichou,
  • Guillermo Navarro-Patron,
  • Javier Jimenez and
  • Jordi Carrabina

23 July 2024

Infant meningitis remains a severe burden on global health, particularly for young infants. Traditional ultrasound imaging techniques are limited in spatial resolution to visualize white blood cells (WBCs) in the cerebrospinal fluid (CSF), which is c...

of 2