The traditional point of view regarding dairy cattle selection has been challenged by recent genomic studies indicating that livestock productivity prediction can be redefined based on the evaluation of genomic and phenotypic data. Several studies th...
Helleborus orientalis L. is a valuable winter-flowering and understory landscape plant, but its application and breeding are hindered by poor heat tolerance and the lack of a robust germplasm evaluation system. In this study, 51 Helleborus L. hybrid...
Background/Objectives: Peanut landraces (Arachis hypogaea L.) from Guizhou, a karst region of southwestern China, represent an underexploited breeding resource whose phenotypic architecture and marker associations remain insufficiently characterized....
Caryopteris incana (Thunb. ex Houtt.) Miq., an endangered species native to western Kyushu, Japan, forms locally isolated populations. In our previous studies, we conducted a distribution survey of 109 populations across four regions and performed ph...
To optimize the varietal structure of fruit crops in arid environments and screen apricot-plum varieties suitable for cultivation in the Aksu region, a systematic agronomic evaluation was conducted to comprehensively analyze the phenotypic diversity...
We used 256 apple germplasm resources for a thorough examination of the genetic diversity associated with 26 phenotypic traits (i.e., genetic diversity analysis, cluster analysis, correlation analysis, principal component analysis, and membership fun...
Late radiation-associated dysphagia (late-RAD) remains a challenge in head and neck cancer (HNC) survivorship, despite advancements in treatment methods. Although Fiberoptic Endoscopic Evaluation of Swallowing (FEES) stands as the preferred diagnosti...
Three new minor components, the pyridoacridine alkaloids 1-hydroxy-deoxyamphimedine (1), 3-hydroxy-deoxyamphimedine (2), debromopetrosamine (3), and three known compounds, amphimedine (4), neoamphimedine (5) and deoxyamphimedine (6), have been isolat...
Leprosy remains a major cause of peripheral neuropathy and permanent disability, with current multidrug regimens challenged by toxicity, treatment duration, and relapse. Although therapeutic innovation is an urgent priority, conventional Phase III ra...
Background/Objectives: Young-onset ischemic stroke shows substantial etiologic heterogeneity. However, the value and diagnostic yield of advanced cardiac and autoimmune evaluations in young adults remain uncertain. Methods: Patients aged 25–55...
Mango is a globally vital tropical commercial fruit crop boasting a sizable industry and remarkable economic benefits. Nevertheless, mango leaves, abundant in carbohydrates, polyphenols and other nutrients, remain underdeveloped in comprehensive reso...
To streamline germplasm preservation, enhance resource utilization, and improve breeding efficiency, a core germplasm bank was established using 24 phenotypic traits and DNP markers from 155 pepper resources across various regions. Selection of the o...
Background/Objectives: Phenotypic antimicrobial susceptibility testing (AST) is essential for guiding timely and effective antibiotic therapy. Rapid and accurate reporting of AST results enables earlier optimization of treatment and supports antimicr...
Toona sinensis is an important “vegetable and timber” tree species that is widely distributed in eastern and southeastern Asia. An efficient mechanism for preserving and utilizing germplasm resources is crucial for speeding up the process...
Objectives: This study aims to explore the histological dimensions of the gingiva and the alveolar mucosa and to evaluate their associations with gingival phenotypic parameters, including gingival thickness (GT), keratinized tissue width (KTW), and g...
Foxtail millet (Setaria italica L.) is an important functional food crop with high photosynthetic efficiency and drought tolerance, and it plays a significant role in arid and semi-arid agricultural systems. However, germplasm resources from Xinjiang...
The ECPGR European Evaluation Network (EVA) for Maize involves genebanks, research institutions, and private breeding companies from nine countries focusing on the valorization of maize genetic resources across Europe. This study describes a diverse...
Crabapples (Malus spp.) are important ornamental trees in northern temperate regions. However, their phenotypic diversity and ornamental values remain poorly characterized, due to a lack of systematic comparison between introduced and domestically br...
Chewing cane is primarily consumed as fresh fruit and contains a variety of essential amino acids and iron. The identification and evaluation of chewing cane germplasm resources are prerequisites for the rational utilization of these resources, and p...
To clarify the genetic background and biological characteristics of grape germplasm resources and provide theoretical support for germplasm innovation and new-variety breeding, we conducted systematic morphological identification and SSR molecular-ma...
Germplasm resources embody the genetic diversity of plants and form the foundation for breeding and the ongoing improvement of elite cultivars. The establishment of germplasm banks, along with their systematic evaluation, constitutes a critical step...
Background: Drug development for leishmaniases treatment follows a very selective process in order to propose drug candidates that possess all the qualities that meet the strict specifications of the pharmaceutical industry. Drug resistance is a limi...
Potato is a globally important staple, but postharvest diseases such as dry rot, caused by Fusarium spp., threaten production and lead to major economic losses and food safety risks. Limited resistant cultivars highlight the need for phenotypic scree...
Lonicera caerulea L. has high nutritional and health value, and it is an important emerging small berry tree species. In this study, the morphology and nutrient composition of 60 cultivars were used to analyze and evaluate the diversity of the genus....
A diploid blueberry mapping population, used previously to map quantitative trait loci (QTL) for chilling requirement and cold hardiness, was evaluated for several plant development and fruit quality traits. Specifically, the population was phenotype...
The breeding of creole cattle from the southern region of Ecuador, also known as Criollo Lojano, is a source of economic support and work for the communities located in the remote areas of the Andes mountains in this region. These cattle are grouped...
Probiotic Lactobacillus species are known to exert health benefits in hosts when administered in adequate quantities. A systematic safety assessment of the strains must be performed before the Lactobacillus strains can be designated as probiotics for...
As a unique woody oil crop in China, Camellia oleifera Abel. germplasm resources show significant genetic diversity in Ya’an City. This study measured 60 phenotypic traits (32 quantitative, 28 qualitative) of 302 accessions to analyze phenotypi...
Background/Objectives: Paracetamol is a widely analgesic and antipyretic drug; however, its limited anti-inflammatory efficacy and safety concerns motivate the search for novel non-opioid alternatives. In this study, a series of 4-hydroxyphenylamino-...
Barley remains the fourth most cultivated cereal crop worldwide and is valued for its versatility in malting and brewing, animal feed, human nutrition, and dietary supplements. The identification of genotypes suitable for breeding or specific end-use...
Background: Pseudoxanthoma elasticum (PXE) is a rare ectopic calcification genetic disease mainly caused by ABCC6 rare sequence variants. The clinical phenotype is characterized by typical dermatological, ophthalmological and cardiovascular manifesta...
Metabolic diseases have diverse etiologies, prolonged courses, and multiorgan involvement, making selection of animal models matched to the research objective and disease stage essential. Zebrafish develop rapidly, are genetically tractable, and supp...
The main objective of this study was to analyze the effects of the inbreeding degree in high-producing primiparous dairy cows genotypically and phenotypically evaluated and its impacts on production and reproductive parameters. Eighty Holstein–...
To comprehensively evaluate 212 tomato accessions and gain an in-depth understanding of their genetic background, 17 major agronomic traits were assessed, and whole-genome resequencing was performed on all materials. The results indicated that the ge...
Centella asiatica (L.) Urb., a perennial herb of the Apiaceae family, is an important medicinal plant with diverse therapeutic applications. In this study, we integrated phenotypic evaluation, SSR markers, and HPLC fingerprinting to assess the divers...
Salinity stress is one of the most severe constraints limiting rice production worldwide. Thus, the development of salt-tolerant rice promises to deal with increasing food demand due to climate change effects. This study investigated the salinity tol...
Elizabethkingia species have emerged as important nosocomial pathogens associated with multidrug resistance and persistent infections. This study aimed to characterize clinical Elizabethkingia isolates from Northern Thailand regarding antimicrobial s...
The common bean (Phaseolus vulgaris L.) is a major food legume and an important plant genetic resource for sustainable agriculture. Effective use of this diversity requires integrated evaluation of phenotypic variation and agronomic performance, with...
Salt stress severely restricts soybean seedling growth and yield formation, and the redundant indicators and low efficiency of conventional salt tolerance evaluation methods limit the large-scale screening and breeding of salt-tolerant soybean germpl...
Achieving global sustainable agriculture requires farmers worldwide to adopt smart agricultural technologies, such as autonomous ground robots. However, most ground robots are either task- or crop-specific and expensive for small-scale farmers and sm...
The Fonni’s dog is an ancient Sardinian breed for livestock and property guarding. In recent years, the number of new registrations to the breeding book has slumped and, thus, this breed risks being lost forever. This work refocuses attention t...
Low temperature exerts severe adverse effects on maize growth, particularly during the seedling stage. Screening for cold-tolerant maize genotypes is highly significant for identifying genes associated with cold tolerance and enhancing maize performa...
Powdery mildew, caused by Blumeria graminis f. sp. hordei (Bgh), severely impacts global barley Hordeum vulgare L. (Hv) production. This investigation evaluated Egyptian barley genotypes to identify novel resistance sources and molecular markers for...
(1) Background: pathological changes in hepatic Langerhans cell histiocytosis (LCH) have been observed; however, corresponding imaging findings can appear vague to physicians and radiologists. The present study aimed to comprehensively illustrate the...
Drug-resistant Klebsiella pneumoniae is a serious clinical problem, and bacteriophages are being investigated again as antibacterial agents. This study describes the phenotypic characterization and a preliminary in vivo evaluation of vB_Kpn_NIIPB-V00...
Hawthorn (Crataegus spp.), a horticultural crop with significant edible, medicinal, and ornamental values, has garnered increasing attention from breeders to markets, leading to continuous emergence of new varieties. Accurate phenotypic characterizat...
The safety profile of Lentilactobacillus buchneri KU200793, which has neuroprotective effects, was comprehensively evaluated through both phenotypic and genotypic analyses. Phenotypically, the strain exhibited no β-hemolysis, mucin degradation,...
Saccharomyces cerevisiae FOSU-QQT (SC.QQT), isolated from pineapple pomace wine, exhibits favorable aroma-producing capabilities. In this study, we performed integrated genomic and phenotypic analyses to comprehensively evaluate its safety profile, p...
This retrospective study evaluates the link between an adverse drug reaction (ADR) or a non-response to treatment and cytochromes P450 (CYP), P-glycoprotein (P-gp) or catechol-O-methyltransferase (COMT) activity in patients taking analgesic drugs for...
Weissella cibaria CMU and CMS1 are known to exert beneficial effects on the oral cavity but have not yet been determined to be generally recognized as safe (GRAS), although they are used as commercial strains in Korea. We aimed to verify the safety o...
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