Ischemic Stroke: Diagnosis and Treatment
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 61
Special Issue Editors
Interests: stroke; stroke thrombolysis; stroke imaging; cerebrovascular circulation; transcranial ultrasonography
Special Issues, Collections and Topics in MDPI journals
Interests: stroke; migraine; clinical neurology; neuroimaging; cerebrovascular circulation
Special Issue Information
Dear Colleagues,
Despite advances in acute treatment, stroke continues to represent a major cause of disability and mortality worldwide. In recent years, we witnessed the milestone of mechanical thrombectomy in acute stroke treatment. Further advances in stroke diagnosis and treatment include the application of reperfusion therapies over an extended time window based on advanced neuroimaging, better understanding of the underlying etiologies of cryptogenic stroke, promising minimally invasive techniques for hematoma evacuation, insights into the mechanisms of stroke-associated neuroinflammation and neurorepair emphasizing sex and age, and, finally, the establishment of the use of tenecteplase within the standard therapeutic window. Furthermore, although advanced neuroimaging is a useful aid in the diagnosis of stroke, it remains a supplement to and not a substitute for correct clinical evaluation. In an era of galloping technology and artificial intelligence, everyday practice of vascular neurology still requires excellent clinical skills.
In this Special Issue of JCM, we aim to focus on all promising and developing areas of clinical and basic stroke research, covering fields from experimental ischemia and neuroprotection in the era of endovascular therapies to the epidemiology of underrecognized vascular risk factors, brain–heart interaction, and advances in reperfusion therapies. Research highlighting evolving treatment and prevention paradigms, diagnostic techniques, and stroke pathophysiology using a multidisciplinary precision medicine-oriented approach lies at the core of this Special Issue.
Dr. Theodoros Karapanayiotides
Dr. Ioanna Koutroulou
Guest Editors
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Keywords
- stroke
- reperfusion therapies
- neuroimaging
- brain ischemia
- intracerebral hemorrhage
- intravenous thrombolysis
- mechanical thrombectomy
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