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204 Results Found

  • Article
  • Open Access
20 Citations
5,039 Views
10 Pages

Evaluation of Passive Immunity Induced by Immunisation Using Two Inactivated gE-deleted Marker Vaccines against Infectious Bovine Rhinotracheitis (IBR) in Calves

  • Stefano Petrini,
  • Cecilia Righi,
  • Carmen Iscaro,
  • Giulio Viola,
  • Paola Gobbi,
  • Eleonora Scoccia,
  • Elisabetta Rossi,
  • Claudia Pellegrini and
  • Gian Mario De Mia

4 January 2020

Different types of vaccines against Infectious Bovine Rhinotracheitis (IBR) are commercially available. Among these, inactivated glycoprotein E (gE)-deleted marker vaccines are commonly used, but their ability to induce passive immunity is poorly kno...

  • Article
  • Open Access
12 Citations
3,169 Views
15 Pages

Introduction: Acrylamide (AA) is a “probably carcinogenic to humans” monomer that can form in heated starchy food and in tobacco smoke. N-Acetyl-S-(2-carbamoylethyl)-L-cysteine (AAMA) and N-Acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine...

  • Article
  • Open Access
877 Views
16 Pages

Three-Dimensional Binary Marker: A Novel Underwater Marker Applicable for Long-Term Deployment Scenarios

  • Alaaeddine Chaarani,
  • Patryk Cieslak,
  • Joan Esteba,
  • Ivan Eichhardt and
  • Pere Ridao

Traditional 2D optical markers degrade quickly in underwater applications due to sediment accumulation and marine biofouling, becoming undetectable within weeks. This paper presents a Three-Dimensional Binary Marker, a novel passive fiducial marker d...

  • Article
  • Open Access
3 Citations
3,608 Views
20 Pages

11 February 2021

In this paper, the motion of the n-vortex system as it collapses to a point in finite time is studied. The motion of vortices is described by the set of ordinary differential equations that we are able to solve analytically. The explicit formula for...

  • Article
  • Open Access
7 Citations
4,142 Views
11 Pages

Effect of Glenohumeral Internal Rotation Deficit on Shoulder in Baseball Pitchers during Fastball Pitching

  • Hwai-Ting Lin,
  • Yu-Chuan Lin,
  • You-Li Chou,
  • Hung-Chien Wu,
  • Rong-Tyai Wang and
  • Paul Pei-His Chou

Previous studies have reported that pitchers with glenohumeral internal rotation deficit (GIRD) may increase the risk of shoulder injury. However, limited information is available regarding the specific effects of GIRD in baseball pitching. The purpo...

  • Proceeding Paper
  • Open Access
4 Citations
2,945 Views
7 Pages

Assessment of Measurement Uncertainty in Optical Marker Tracking of High-Speed Motion

  • Paul Lückemann,
  • Steph Forrester,
  • Aimée Mears,
  • Jonathan Shepherd and
  • Jon Roberts

Optical marker tracking is used in research environments to understand the dynamics of moving objects of interest. Due to the complexity of the systems and the wide field of applications, there is no simple method to assess system accuracy. In this a...

  • Article
  • Open Access
19 Citations
6,110 Views
10 Pages

Development of an Embedded Myokinetic Prosthetic Hand Controller

  • Francesco Clemente,
  • Valerio Ianniciello,
  • Marta Gherardini and
  • Christian Cipriani

17 July 2019

The quest for an intuitive and physiologically appropriate human machine interface for the control of dexterous prostheses is far from being completed. In the last decade, much effort has been dedicated to explore innovative control strategies based...

  • Review
  • Open Access
11 Citations
6,450 Views
23 Pages

Sensor-Based Assessment of Social Isolation and Loneliness in Older Adults: A Survey

  • Deepa Prabhu,
  • Mahnoosh Kholghi,
  • Moid Sandhu,
  • Wei Lu,
  • Katie Packer,
  • Liesel Higgins and
  • David Silvera-Tawil

16 December 2022

Social isolation (SI) and loneliness are ‘invisible enemies’. They affect older people’s health and quality of life and have significant impact on aged care resources. While in-person screening tools for SI and loneliness exist, sta...

  • Article
  • Open Access
2 Citations
1,306 Views
23 Pages

Subchronic Toxicity and Effect of the Methanolic Extract of Micromeria frivaldszkyana (Degen) Velen on Cognition in Male Wistar Rats

  • Elisaveta Apostolova,
  • Kristina Stavrakeva,
  • Vesela Kokova,
  • Ivica Dimov,
  • Mariya Choneva,
  • Delyan Delev,
  • Ilia Kostadinov,
  • Iliya Bivolarski,
  • Maria Koleva and
  • Tsvetelina Mladenova
  • + 2 authors

15 June 2025

Recently, compounds of plant origin have been the focus of increased scientific interest. Micromeria frivaldszkyana is a rare species endemic to Bulgaria, whose biological activity remains unknown. This article aims to evaluate the subchronic toxicit...

  • Article
  • Open Access
4 Citations
2,386 Views
12 Pages

Assessment of BoAHV-1 Seronegative Latent Carrier by the Administration of Two Infectious Bovine Rhinotracheitis Live Marker Vaccines in Calves

  • Stefano Petrini,
  • Cecilia Righi,
  • Giulia Costantino,
  • Eleonora Scoccia,
  • Paola Gobbi,
  • Claudia Pellegrini,
  • Michela Pela,
  • Monica Giammarioli,
  • Giulio Viola and
  • Roberto Sabato
  • + 2 authors

3 February 2024

Seronegative latent carriers (SNLCs) are animals that carry the virus without detectable antibodies and pose a risk for disease transmission and diagnostic challenges, suggesting the importance of consideration of marker vaccines in managing them. Th...

  • Article
  • Open Access
2,663 Views
11 Pages

Foam Roller Post-High-Intensity Training for CrossFit Athletes: Does It Really Help with Recovery?

  • Fernando Zarzosa-Alonso,
  • Alejandra Alonso-Calvete,
  • Martín Otero-Agra,
  • María Fernández-Méndez,
  • Felipe Fernández-Méndez,
  • Francisco Martín-Rodríguez,
  • Roberto Barcala-Furelos and
  • Myriam Santos-Folgar

Background/Objectives: Foam rolling is a new and emergent recovery tool in sports. The aim of this study seeks to compare the acute effects of foam rolling and passive rest on recovery markers in CrossFit athletes following a high-intensity workout....

  • Review
  • Open Access
44 Citations
10,822 Views
43 Pages

State of the Art in Tumor Antigen and Biomarker Discovery

  • Klervi Even-Desrumeaux,
  • Daniel Baty and
  • Patrick Chames

9 June 2011

Our knowledge of tumor immunology has resulted in multiple approaches for the treatment of cancer. However, a gap between research of new tumors markers and development of immunotherapy has been established and very few markers exist that can be used...

  • Article
  • Open Access
3 Citations
4,630 Views
25 Pages

15 September 2023

The morpheme ‘give’ is among the most well-studied lexical items in the realm of grammaticalization. This study sets out to provide a typological and areal analysis of the distinct forms and multiple functions of ‘give’ in 27...

  • Article
  • Open Access
174 Views
17 Pages

3D Analysis of the Initial and End Positions of an Active and Passive Prone Hip Extension Test and Its Correlation with Lower Limb Isokinetic Neuromuscular Function of College Students: A Pilot Study

  • José Lumini,
  • Benjamin Hedirian,
  • Pedro Fonseca,
  • Andrea Ribeiro,
  • André Chenu Schneider,
  • António M. Monteiro and
  • João Paulo Vilas-Boas

1 December 2025

Introduction: Manual therapists routinely evaluate changes in pain, movement, and function through clinical tests that support clinical reasoning. The Prone Hip Extension Test (PHET) is commonly used as a self-perturbation task to assess lumbopelvic...

  • Article
  • Open Access
9 Citations
1,490 Views
8 Pages

GantryMate: A Modular MR-Compatible Assistance System for MR-Guided Needle Interventions

  • Andreas Reichert,
  • Michael Bock,
  • Michael Vogele and
  • Axel Joachim Krafft

1 June 2019

Percutaneous minimally invasive interventions are difficult to perform in closed-bore high-field magnetic resonance systems owing to the limited space between magnet and patient. To enable magnetic resonance–guided needle interventions, we combine a...

  • Article
  • Open Access
15 Citations
4,269 Views
14 Pages

Self-Reported Exposure to ETS (Environmental Tobacco Smoke), Urinary Cotinine, and Oxidative Stress Parameters in Pregnant Women—The Pilot Study

  • Lubica Argalasova,
  • Ingrid Zitnanova,
  • Diana Vondrova,
  • Monika Dvorakova,
  • Lucia Laubertova,
  • Jana Jurkovicova,
  • Juraj Stofko,
  • Michael Weitzman,
  • Iveta Waczulikova and
  • Martin Simko

Background: Exposure to ETS (environmental tobacco smoke) is one of the most toxic environmental exposures. Objective: To investigate the association of ETS with physiological, biochemical, and psychological indicators, as well as with urine antioxid...

  • Feature Paper
  • Article
  • Open Access
14 Citations
5,966 Views
20 Pages

Critical Evaluation of Different Passive Sampler Materials and Approaches for the Recovery of SARS-CoV-2, Faecal-Indicator Viruses and Bacteria from Wastewater

  • Davey L. Jones,
  • Jasmine M. S. Grimsley,
  • Jessica L. Kevill,
  • Rachel Williams,
  • Cameron Pellett,
  • Kathryn Lambert-Slosarska,
  • Andrew C. Singer,
  • Gwion B. Williams,
  • Rafael Bargiela and
  • Robert W. Brown
  • + 2 authors

6 November 2022

During the COVID-19 pandemic, wastewater-based epidemiology (WBE) has proven to be an effective tool for monitoring the prevalence of SARS-CoV-2 in urban communities. However, low-cost, simple, and reliable wastewater sampling techniques are still ne...

  • Article
  • Open Access
1,264 Views
20 Pages

Analysis of Neurophysiological Correlates of Mental Fatigue in Both Monotonous and Demanding Driving Conditions

  • Francesca Dello Iacono,
  • Luca Guinti,
  • Marianna Cecchetti,
  • Andrea Giorgi,
  • Dario Rossi,
  • Vincenzo Ronca,
  • Alessia Vozzi,
  • Rossella Capotorto,
  • Fabio Babiloni and
  • Pietro Aricò
  • + 5 authors

16 September 2025

Background/Objectives: Mental fatigue during driving, whether passive (arising from monotony) or active (caused by cognitive overload), is a critical factor for road safety. Despite the growing interest in monitoring techniques based on neurophysiolo...

  • Communication
  • Open Access
14 Citations
3,248 Views
8 Pages

High Connectivity of the White Seabream (Diplodus sargus, L. 1758) in the Aegean Sea, Eastern Mediterranean Basin

  • Athanasios Exadactylos,
  • Dimitrios Vafidis,
  • Costas S. Tsigenopoulos and
  • Georgios A. Gkafas

15 November 2019

Population dynamics in the marine realm can shape species’ spatial structure and genetic variability between given geographical areas. Connectivity is an important factor of species’ population structure. In this study, we examined the genetic divers...

  • Article
  • Open Access
11 Citations
5,544 Views
16 Pages

Detection of Simulated Fukushima Daichii Fuel Debris Using a Remotely Operated Vehicle at the Naraha Test Facility

  • Matthew Nancekievill,
  • Jose Espinosa,
  • Simon Watson,
  • Barry Lennox,
  • Ashley Jones,
  • Malcolm J. Joyce,
  • Jun-ichi Katakura,
  • Keisuke Okumura,
  • So Kamada and
  • Michio Katoh
  • + 1 author

22 October 2019

The use of robotics in harsh environments, such as nuclear decommissioning, has increased in recent years. Environments such as the Fukushima Daiichi accident site from 2011 and the Sellafield legacy ponds highlight the need for robotic systems capab...

  • Article
  • Open Access
20 Citations
5,402 Views
15 Pages

Surface Characterization, Corrosion Resistance and in Vitro Biocompatibility of a New Ti‐Hf‐Mo‐Sn Alloy

  • Raluca Ion,
  • Silviu Iulian Drob,
  • Muhammad Farzik Ijaz,
  • Cora Vasilescu,
  • Petre Osiceanu,
  • Doina‐Margareta Gordin,
  • Anisoara Cimpean and
  • Thierry Gloriant

4 October 2016

A new superelastic Ti‐23Hf‐3Mo‐4Sn biomedical alloy displaying a particularly large recovery strain was synthesized and characterized in this study. Its native passive film is very thick (18 nm) and contains very protective TiO2, Ti2O3, HfO2, MoO2, a...

  • Article
  • Open Access
2,209 Views
15 Pages

Tobacco Smoke Exposure and Oxidative Stress: The Role of Circulating Lipopolysaccharides in Heated and Conventional Products

  • Lorenzo Loffredo,
  • Enrico Maggio,
  • Simona Bartimoccia,
  • Arianna Magna,
  • Chiara Maria Totè,
  • Chiara Bagnato,
  • Bianca Laura Cinicola,
  • Federica Armeli,
  • Angela Leonardo and
  • Alessandra D’Amico
  • + 10 authors

31 October 2025

Background: Exposure to tobacco smoke, from conventional tobacco cigarettes (CTC) or heated tobacco products (HTPs), increases oxidative stress, causing endothelial dysfunction and higher cardiovascular risk. It is unclear whether smoke exposure also...

  • Review
  • Open Access
34 Citations
12,626 Views
30 Pages

A Review of Recent Advances in Flexible Wearable Sensors for Wound Detection Based on Optical and Electrical Sensing

  • Xianyou Sun,
  • Yanchi Zhang,
  • Chiyu Ma,
  • Qunchen Yuan,
  • Xinyi Wang,
  • Hao Wan and
  • Ping Wang

23 December 2021

Chronic wounds that are difficult to heal can cause persistent physical pain and significant medical costs for millions of patients each year. However, traditional wound care methods based on passive bandages cannot accurately assess the wound and ma...

  • Article
  • Open Access
4 Citations
4,776 Views
21 Pages

A Deep Learning Model for Markerless Pose Estimation Based on Keypoint Augmentation: What Factors Influence Errors in Biomechanical Applications?

  • Ana V. Ruescas-Nicolau,
  • Enrique Medina-Ripoll,
  • Helios de Rosario,
  • Joaquín Sanchiz Navarro,
  • Eduardo Parrilla and
  • María Carmen Juan Lizandra

17 March 2024

In biomechanics, movement is typically recorded by tracking the trajectories of anatomical landmarks previously marked using passive instrumentation, which entails several inconveniences. To overcome these disadvantages, researchers are exploring dif...

  • Article
  • Open Access
16 Citations
5,212 Views
21 Pages

HMGB1 Promotes In Vitro and In Vivo Skeletal Muscle Atrophy through an IL-18-Dependent Mechanism

  • Trung-Loc Ho,
  • Chih-Hsin Tang,
  • Sunny Li-Yun Chang,
  • Chun-Hao Tsai,
  • Hsien-Te Chen and
  • Chen-Ming Su

6 December 2022

Skeletal muscle atrophy occurs due to muscle wasting or reductions in protein associated with aging, injury, and inflammatory processes. High-mobility group box-1 (HMGB1) protein is passively released from necrotic cells and actively secreted by infl...

  • Article
  • Open Access
6 Citations
4,813 Views
10 Pages

Cotinine as a Sentinel of Canine Exposure to Tobacco Smoke

  • Debora Groppetti,
  • Giulia Pizzi,
  • Alessandro Pecile,
  • Valerio Bronzo and
  • Silvia Michela Mazzola

16 February 2023

The adverse health effects of both active and passive tobacco smoke have been well-known in humans for a long time. It is presumable that even pets, which intimately share the owner’s lifestyle, may be exposed to the same risks. This study aime...

  • Article
  • Open Access
31 Citations
5,151 Views
14 Pages

Sesame Lignans Suppress Age-Related Cognitive Decline in Senescence-Accelerated Mice

  • Satomi Shimoyoshi,
  • Daisuke Takemoto,
  • Yoshiko Ono,
  • Yoshinori Kitagawa,
  • Hiroshi Shibata,
  • Susumu Tomono,
  • Keiko Unno and
  • Keiji Wakabayashi

12 July 2019

Sesame lignans, which are biologically active compounds present in sesame seeds and oil, are known to have neuroprotective effects in several models of brain dysfunction. However, the effects of sesame lignans on age-related brain dysfunction are not...

  • Article
  • Open Access
2 Citations
4,109 Views
10 Pages

A New Test for Achilles Tendinopathy Based on Kager’s Fat Pad Clinical Assessment Predictive Values

  • David Rodríguez-Sanz,
  • Marta Elena Losa-Iglesias,
  • Ricardo Becerro de Bengoa-Vallejo,
  • Zacarías Sánchez-Milá,
  • Hend Adel Abdelhalim Dorgham,
  • Ahmed Ebrahim Elerian,
  • Tian Yu,
  • César Calvo-Lobo,
  • Jorge Velázquez-Saornil and
  • Eva María Martínez Jimene

9 August 2023

Background This study aimed to check the diagnostic accuracy of a new test to identify Achilles tendinopathy. Study Design: Observational study. Methods: Seventy patients recruited from a private medical centre met the diagnostic criteria for unilate...

  • Article
  • Open Access
56 Citations
8,292 Views
25 Pages

Global DNA Hypomethylation in Epithelial Ovarian Cancer: Passive Demethylation and Association with Genomic Instability

  • Wa Zhang,
  • David Klinkebiel,
  • Carter J. Barger,
  • Sanjit Pandey,
  • Chittibabu Guda,
  • Austin Miller,
  • Stacey N. Akers,
  • Kunle Odunsi and
  • Adam R. Karpf

24 March 2020

A hallmark of human cancer is global DNA hypomethylation (GDHO), but the mechanisms accounting for this defect and its pathological consequences have not been investigated in human epithelial ovarian cancer (EOC). In EOC, GDHO was associated with adv...

  • Article
  • Open Access
18 Citations
6,251 Views
15 Pages

Skin Strain Analysis of the Scapular Region and Wearables Design

  • Arianna Carnevale,
  • Emiliano Schena,
  • Domenico Formica,
  • Carlo Massaroni,
  • Umile Giuseppe Longo and
  • Vincenzo Denaro

26 August 2021

Monitoring scapular movements is of relevance in the contexts of rehabilitation and clinical research. Among many technologies, wearable systems instrumented by strain sensors are emerging in these applications. An open challenge for the design of th...

  • Article
  • Open Access
19 Citations
5,122 Views
39 Pages

Monocular-Based Pose Estimation Based on Fiducial Markers for Space Robotic Capture Operations in GEO

  • Roberto Opromolla,
  • Claudio Vela,
  • Alessia Nocerino and
  • Carlo Lombardi

8 September 2022

This paper tackles the problem of spacecraft relative navigation to support the reach and capture of a passively cooperative space target using a chaser platform equipped with a robotic arm in the frame of future operations such as On Orbit Servicing...

  • Article
  • Open Access
4 Citations
2,754 Views
12 Pages

27 April 2021

Clinical use of portable optical tracking system in dentistry could improve the analysis of mandibular movements for diagnostic and therapeutic purposes. A new workflow for the acquisition of mandibular kinematics was developed. Reproducibility of me...

  • Article
  • Open Access
5 Citations
2,344 Views
27 Pages

Vision-Based Underwater Docking Guidance and Positioning: Enhancing Detection with YOLO-D

  • Tian Ni,
  • Can Sima,
  • Wenzhong Zhang,
  • Junlin Wang,
  • Jia Guo and
  • Lindan Zhang

This study proposed a vision-based underwater vertical docking guidance and positioning method to address docking control challenges for human-operated vehicles (HOVs) and unmanned underwater vehicles (UUVs) under complex underwater visual conditions...

  • Study Protocol
  • Open Access
6 Citations
4,125 Views
19 Pages

ECOCAPTURE@HOME: Protocol for the Remote Assessment of Apathy and Its Everyday-Life Consequences

  • Valérie Godefroy,
  • Richard Levy,
  • Arabella Bouzigues,
  • Armelle Rametti-Lacroux,
  • Raffaella Migliaccio and
  • Bénédicte Batrancourt

Apathy, a common neuropsychiatric symptom associated with dementia, has a strong impact on patients’ and caregivers’ quality of life. However, it is still poorly understood and hard to define. The main objective of the ECOCAPTURE programme is to defi...

  • Article
  • Open Access
7 Citations
2,280 Views
14 Pages

19 March 2024

To date, clinical expert opinion is the gold standard diagnostic technique for Parkinson’s disease (PD), and continuous monitoring is a promising candidate marker. This study assesses the feasibility and performance of a new wearable tool for s...

  • Communication
  • Open Access
4 Citations
4,924 Views
11 Pages

Relationships between Serum Biomarkers of Oxidative Stress and Tobacco Smoke Exposure in Patients with Mental Disorders

  • Ana-Maria Vlasceanu,
  • Daniela Gradinaru,
  • Miriana Stan,
  • Viorela G. Nitescu and
  • Daniela Luiza Baconi

The role of cigarette smoking as an aggravating factor of systemic oxidative stress in patients with mental disorders has not been extensively investigated, although significantly higher rates of smoking are recorded in these subjects in comparison w...

  • Article
  • Open Access
6,095 Views
13 Pages

Effects of Cold-Water Immersion on Muscle Damage Markers, Physical Performance, and Skin Temperature of Kung Fu Athletes

  • Gilvandro Oliveira Barros,
  • Felipe J. Aidar,
  • Raphael Fabricio de Souza,
  • Ciro José Brito,
  • Renato Méndez-delCanto,
  • Jymmys Lopes dos Santos,
  • Paulo Francisco Almeida-Neto,
  • Breno Guilherme de Araújo Tinoco Cabral,
  • Nuno Domingos Garrido and
  • Victor Machado Reis
  • + 2 authors

Objective: This study aimed to evaluate the effects of cold-water immersion (CWI) on post-training recovery in Kung Fu athletes. Methods: In a 3-week crossover design, 16 Kung Fu athletes (22.00 ± 5.95 years, 76.90 ± 9.74 kg) were divid...

  • Article
  • Open Access
7 Citations
3,046 Views
12 Pages

Changes in Volatile Composition of Cape Hake Fillets under Modified Atmosphere Packaging Systems during Cold Storage

  • Umezuruike Linus Opara,
  • Tobi Fadiji,
  • Oluwafemi James Caleb and
  • Adebanji Olasupo Oluwole

29 April 2022

Fresh ready-to-cook fish fillets are susceptible to loss of freshness and accumulation of off-odour due to accelerated microbial spoilage. Suboptimal storage temperature and packaging conditions accelerate this process, limiting the economic potentia...

  • Article
  • Open Access
2 Citations
3,005 Views
14 Pages

Clinical and Ultrasound Evaluation of Hemiplegic Shoulder Pain in Stroke Patients: A Longitudinal Observational Study Starting in the First Hours After Stroke

  • Filippo Cotellessa,
  • William Campanella,
  • Luca Puce,
  • Maria Cesarina May,
  • Marta Ponzano,
  • Riccardo Picasso,
  • Matteo Mordeglia,
  • Davide Subbrero,
  • Ester Cecchella and
  • Laura Mori
  • + 4 authors

11 March 2025

Background and Objectives: Hemiplegic shoulder pain (HSP) is a common and disabling complication in stroke patients, yet its pathogenesis remains unclear. This longitudinal study aimed to investigate the clinical and ultrasound characteristics of HSP...

  • Article
  • Open Access
1,327 Views
16 Pages

7 June 2025

This study analyses for the first time the genetic diversity, connectivity, and evolutionary dynamics of the small red scorpionfish (Scorpaena notata) in the Balearic Islands, using two mitochondrial DNA markers: Cytochrome c oxidase subunit I (COI)...

  • Article
  • Open Access
25 Citations
5,536 Views
18 Pages

Personal NO2 and Volatile Organic Compounds Exposure Levels are Associated with Markers of Cardiovascular Risk in Women in the Cape Town Region of South Africa

  • Frans Everson,
  • Patrick De Boever,
  • Tim S. Nawrot,
  • Nandu Goswami,
  • Mashudu Mthethwa,
  • Ingrid Webster,
  • Dries S. Martens,
  • Nyiko Mashele,
  • Sana Charania and
  • Festus Kamau
  • + 1 author

Exposure to ambient NO2 and benzene, toluene ethyl-benzene and m+p- and o-xylenes (BTEX) is associated with adverse cardiovascular effects, but limited information is available on the effects of personal exposure to these compounds in South African p...

  • Article
  • Open Access
2 Citations
3,817 Views
17 Pages

12 September 2024

Cerebral ischemic stroke is a major cause of death worldwide due to brain cell death resulting from ischemia-reperfusion injury. However, effective treatment approaches for patients with ischemic stroke are still lacking in clinical practice. This st...

  • Article
  • Open Access
17 Citations
4,183 Views
13 Pages

The Vascular Side of Chronic Bed Rest: When a Therapeutic Approach Becomes Deleterious

  • Anna Pedrinolla,
  • Alessandro L. Colosio,
  • Roberta Magliozzi,
  • Elisa Danese,
  • Emine Kirmizi,
  • Stefania Rossi,
  • Silvia Pogliaghi,
  • Massimiliano Calabrese,
  • Matteo Gelati and
  • Ettore Muti
  • + 6 authors

27 March 2020

The interplay between chronic constraint and advanced aging on blood flow, shear-rate, vascular function, nitric oxide (NO)-bioavailability, microcirculation, and vascular inflammation factors is still a matter of debate. Ninety-eight individuals (Yo...

  • Article
  • Open Access
3 Citations
3,541 Views
10 Pages

Characteristics of Pedaling Muscle Stiffness among Cyclists of Different Performance Levels

  • Isaac López-Laval,
  • Rafel Cirer-Sastre,
  • Francisco Corbi and
  • Sebastian Sitko

11 June 2021

Background and Objectives: The aim of the present study was to compare the impact of an incremental exercise test on muscle stiffness in the rectus femoris (RF), vastus lateralis (VL), biceps femoris (BF), and gastrocnemius (GL) among road cyclists o...

  • Article
  • Open Access
2,086 Views
17 Pages

19 March 2025

Loneliness is a global issue which is particularly prevalent among college students, where it poses risks to mental health and academic success. Chronic loneliness can manifest in two primary forms: social loneliness, which is defined by a lack of be...

  • Article
  • Open Access
18 Citations
4,944 Views
18 Pages

Extracellular Vesicles Tropism: A Comparative Study between Passive Innate Tropism and the Active Engineered Targeting Capability of Lymphocyte-Derived EVs

  • Tania Limongi,
  • Francesca Susa,
  • Bianca Dumontel,
  • Luisa Racca,
  • Michela Perrone Donnorso,
  • Doriana Debellis and
  • Valentina Cauda

18 November 2021

Cellular communications take place thanks to a well-connected network of chemical–physical signals, biomolecules, growth factors, and vesicular messengers that travel inside or between cells. A deep knowledge of the extracellular vesicle (EV) system...

  • Article
  • Open Access
17 Citations
4,126 Views
19 Pages

Role of Sphingosine 1-Phosphate Signalling Axis in Muscle Atrophy Induced by TNFα in C2C12 Myotubes

  • Caterina Bernacchioni,
  • Veronica Ghini,
  • Roberta Squecco,
  • Eglantina Idrizaj,
  • Rachele Garella,
  • Elisa Puliti,
  • Francesca Cencetti,
  • Paola Bruni and
  • Chiara Donati

28 January 2021

Skeletal muscle atrophy is characterized by a decrease in muscle mass causing reduced agility, increased fatigability and higher risk of bone fractures. Inflammatory cytokines, such as tumor necrosis factor-alpha (TNFα), are strong inducers of...

  • Article
  • Open Access
12 Citations
3,692 Views
16 Pages

7 July 2020

Banhasasim-tang (BHS) is an herbal medicine that has been widely used in East Asia to treat various symptoms associated with upper abdomen swelling. BHS has not been studied previously for neuroinflammation or cognitive disorder. Here, we use a lipop...

  • Review
  • Open Access
18 Citations
5,209 Views
20 Pages

Gauging the Impact of Cancer Treatment Modalities on Circulating Tumor Cells (CTCs)

  • Trevor J. Mathias,
  • Katarina T. Chang,
  • Stuart S. Martin and
  • Michele I. Vitolo

21 March 2020

The metastatic cascade consists of multiple complex steps, but the belief that it is a linear process is diminishing. In order to metastasize, cells must enter the blood vessels or body cavities (depending on the cancer type) via active or passive me...

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