Background: One important determinant in choosing a treatment modality is spinal instability. Clear management guidelines are suggested for stable and unstable spinal metastatic lesions, but lesions in the intermediate instability category (SINS [spi...
Objectives: The current study aimed to evaluate the effect of denosumab on patients with impending instability due to spinal metastasis, including whether it can improve spinal instability neoplastic score (SINS) and reduce the need for surgical trea...
Background: Adequate assessment of spinal instability using the spinal instability neoplastic score (SINS) frequently guides surgical therapy in spinal epidural osseous metastases and subsequently influences neurological outcome. However, how to surg...
2 April 2013
It is clear that high-dose radiation is harmful. However, despite extensive research, assessment of potential health-risks associated with exposure to low-dose radiation (at doses below or equal to 0.1 Gy) is still challenging. Recently, we reported...
This study explores the influence of chinstrap stiffness in baseball helmets on brain stress distribution during high-velocity impacts through a computational biomechanical model integrating neuroanatomical structures and helmet components. Using a f...
Telomeres are highly susceptible to oxidative DNA damage, particularly 8-oxoguanine (8-oxoG), which is processed by glycosylase-initiated base excision repair (BER). OGG1 removes 8-oxoG opposite C, and MUTYH removes A misinserted opposite 8-oxoG to p...
The instability of hard and brittle rock often leads to disastrous consequences in underground engineering. Under various surrounding rock pressure conditions, in situ stress induces corresponding deformation and damage to the floor post-mining. Ther...
The occurrence of adiabatic shear bands, as an instability phenomenon, is viewed as a precursor to failure caused by instability at high strain rates. Metastable β titanium alloys are extensively utilized due to their excellent mechanical proper...
Gas–liquid two-phase flow instability is a key issue affecting the safety and efficiency of industrial systems, and the accurate characterization of its multiscale dynamic characteristics remains a challenge. This study proposes a novel approac...
The onset of convection in an inclined porous layer which is heated internally by a uniform distribution of heat sources is considered. We investigate the combined effects of inclination, anisotropy and internal heat generation on the linear instabil...
When eccentric live loads are applied on the deck overhang of steel-box girder bridges, torsional moments, comprising pure torsional and distortional moments are generated on the box sections. The torsional moment on the bridge girders distorts the b...
Osaka’s public high school admissions system uses a common score-based priority order and schools’ preferences, while restricting each student to reporting a single school. We show that the Osaka mechanism is neither priority-stable nor p...
Recent years have witnessed outstanding success in supervised domain adaptive person re-identification (ReID). However, the model often suffers serious performance drops when transferring to another domain in real-world applications. To address the d...
Background: The arthroscopic Broström procedure is a promising treatment for chronic ankle instability. However, little is known regarding the location of the intermediate superficial peroneal nerve at the level of the inferior extensor retinacu...
This paper investigated the influence of surface internal energy instability caused by the gravitational tilt angle on solutocapillary convection. The results showed that the spatio-temporal evolution of solutocapillary convection in a non-axisymmetr...
Recombinogenic DNA damage can initiate chromosomal rearrangements that can alter gene expression or accelerate cancer progression in higher eukaryotes. Thus, there is a critical need to identify genes that suppress chromosomal rearrangements and envi...
Meningiomas are common tumors of the central nervous system. The grading system established by the World Health Organization (WHO) has recently included pTERT mutations and CDKN2A/B homozygous deletions as criteria for grade 3, owing to their associa...
Currently, there are billions of connected devices, and the Internet of Things (IoT) has boosted these numbers. In the case of private networks, a few hundred devices connected can cause instability and even data loss in communication. In this articl...
The most potent of the indole diterpenes, lolitrem B, is found in perennial ryegrass (Lolium perenne L.) infected with the endophyte Epichloë festucae var. lolii (also termed LpTG-1). Ingestion causes a neurological syndrome in grazing livestock...
The instability of double-cavern structure subjected to dynamic disturbances is a key issue for deep rock engineering. To investigate the dynamic responses of deep double U-shaped caverns, comprehensive analyses are conducted by Particle Flow Code (P...
Background/Objectives: The incidence, timing, and predictors of hemodynamic and respiratory deterioration in patients with high-risk or intermediate-high-risk pulmonary embolism (PE) undergoing pulmonary mechanical thrombectomy (PMT) remain poorly un...
We investigate the effect of horizontal quasi-periodic oscillation on the stability of two superimposed immiscible fluid layers confined in a horizontal Hele-Shaw cell. To approximate real oscillations, a quasi-periodic oscillation with two incommens...
In this paper, a simple and effective self-adaptive material interpolation scheme is proposed to solve the numerical instability problem, which may occur in topology optimization considering geometrical nonlinearity when using density-based method. T...
In this study, we developed a palladium-catalyzed decarbonylative nucleophilic halogenation reaction using inexpensive and readily available acid anhydrides as substrates. This approach effectively circumvents the instability of acyl chlorides and th...
Laser weld quality remains a critical priority across nearly all industries. However, identifying optimal laser parameter sets continues to be highly challenging, often relying on costly, time-consuming trial-and-error experiments. This difficulty is...
Background/Objectives: As a representative anatomic ankle ligament repair technique, the Broström procedure continues to be modified to reach better clinical outcomes, superior mechanical stability, early rehabilitation, and minimal risk of recu...
High-quality X-ray observations of planetary nebulae (PNe) have demonstrated that the X-ray-emitting gas in their hot bubbles have temperatures in the small range
The aim of this study is to evaluate a new user-friendly scoring system, namely the BETTY score, that aims to predict 30-day patient outcomes after surgery. In this first description, we rely on a population of prostate cancer patients undergoing rob...
This study re-examines the monetary “black box” in India by investigating whether monetary-policy transmission is state-dependent across different interest-rate environments. Using quarterly data spanning 1993Q1–2024Q2, it construct...
Although diaryl tellurides are parent organotellurium compounds, their synthesis methods, especially for unsymmetrical ones, are limited. This may be due to the instability of diaryl tellurides and their synthesis intermediates under reaction conditi...
The CHEK2 gene is involved in the repair of damaged DNA. CHEK2 germline mutations impair this repair mechanism, causing genomic instability and increasing the risk of various cancers, including papillary thyroid carcinoma (PTC). Here, we asked whethe...
Although many researchers have begun to study the area of Cyber Physical Social Sensing (CPSS), few are focused on robotic sensors. We successfully utilize robots in CPSS, and propose a sensor trajectory planning method in this paper. Trajectory plan...
The effect of the instability of the interface morphology due to mechanical disturbances and acceleration changes (or gravity flutter) on Marangoni convective stability has been confirmed via space experiments. However, compared with the research on...
The near-wake structure resulting from the interaction between the water and the cylinder is researched. The wake characteristics for the smooth cylinder and the cylinder with different numbers of grooves are measured by high-speed particle image vel...
In this work it is demonstrated that enantiomerically enriched N-alkyl 2-oxazolinylazetidines undergo exclusive α-lithiation, and that the resulting lithiated intermediate is chemically stable but configurationally labile under the given experi...
Transition metal alloys have emerged as promising electrocatalysts due to their ability to modulate key parameters, such as d-band electron filling, Fermi level energy, and interatomic spacing, thereby influencing their affinity towards reaction inte...
The incorporation of MAX phase interface layers into silicon carbide (SiC) composites has been shown to significantly enhance mechanical properties, particularly under irradiation conditions. However, conventional Ti-based MAX phases suffer from ther...
We discuss the use and importance of pulsating variable stars as population tracers in Local Group galaxies. Among bright variable crossing the classical instability strip, we mostly focus on RR Lyrae stars and Anomalous Cepheids. We discuss their pu...
Optimizing the bias modulation of a fiber-optic gyroscope is crucial to improving its precision. In this study, we propose and demonstrate the use of multiple harmonics of sinusoidal modulation as an intermediate alternative to the widely used modula...
Rock failure generally leads to serious consequences, and it is significant to obtain the precursor information prior to failure using associated techniques. Thus, it is essential to acquire and probe the relevant precursor information. In this study...
The individual risk to progression is unclear for intermediate risk prostate cancer patients. To assess their risk to progression, we examined the level of genomic instability in circulating tumor cells (CTCs) using quantitative three-dimensional (3D...
Intermediate monocytes (CD14++CD16+), a highly pro-inflammatory subset, are linked to endothelial activation, thrombus formation, and poor outcomes in acute coronary syndrome (ACS), suggesting a role in the transition to plaque vulnerability. MicroRN...
This paper presents a comprehensive analytical and numerical investigation of the cubic nonlinear Schrödinger equation derived from the heavy ion-acoustic wave (HIAW) model, which governs the evolution of weakly nonlinear wave packets and their...
Delayed carpal instability after healed juvenile antebrachial fractures presents a diagnostic and surgical challenge when retained implants occupy the site required for arthrodesis. A 3-year-old, 2.58 kg, neutered male Maltese dog presented with left...
During the winter from 2009 to 2013, the mixed layer reached the seafloor at about 2500 m in the northwestern Mediterranean Sea. Intense fronts around the deep convection area were repeatedly sampled by autonomous gliders. Subduction down to 200–300...
The reduction of the sintering temperature of doped ceria ceramics remains an open challenge for their real exploitation as electrolytes for intermediate temperature solid oxide fuel cell (IT-SOFCs) at the industrial level. In this work, we have used...
Paradoxes of dry friction were discovered by Painlevé in 1895 and caused a controversy on whether the Coulomb–Amontons laws of dry friction are compatible with the Newtonian mechanics of the rigid bodies. Various resolutions of the parad...
Variability, intermittency, and limited controllability are inherent characteristics of photovoltaic (PV) generation that result in inaccurate solutions to scheduling problems and the instability of the power grid. As the penetration level of PV gene...
Lead halide perovskites have emerged as promising materials for various optoelectronic applications. For photovoltaics, the reference compound is the 3D perovskite (MA)PbI3 (MA+ = methylammonium). However, this material suffers from instabilities tow...
Cemented coal gangue backfill (CCGB) is an important material for the resource utilization of mining solid waste, and its long-term stability is strongly affected by aggregate gradation. In this study, aggregate mass fractal dimension was used to cha...
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