1,038 Results Found

A novel type of neural network with an architecture based on physics is proposed. The network structure builds on a body of analytical modifications of classical numerical methods. A feature of the constructed neural networks is defining parameters o...

The article discusses the problem of a preliminary analytical method for modifying the shape of a rocket’s nose. The purpose of this method is to determine the shape that minimizes aerodynamic drag, in the context of modifying a ballistic missi...

An increase in the world population and its life expectancy, as well as the ongoing concern about our physical appearance, have elevated the relevance of dental implantology in recent decades. Engineering strategies to improve the survival rate of de...

Circulating microRNAs (miRNAs) are useful biomarkers of hemolysis. Since blood cells are the main origins of circulating miRNAs, we evaluated blood cell-related pre-analytical modification of the miRNA signatures during blood drawing and serum proces...

Nucleic acid modifications play important roles in biological activities and disease occurrences, and have been considered as cancer biomarkers. Due to the relatively low amount of nucleic acid modifications in biological samples, it is necessary to...

Birkhoff theory exhibits an analytical steady state liner collapse model of shaped charges followed by jetting process. It also provides the fundamental idea in study of shaped charges and has widened its application in many areas, including a config...

We present the modification of ethylene-propylene rubber (EPM) with vinyltetra-methydisiloxane (VTMDS) via reactive extrusion to create a new silicone-based material with the potential for high-performance applications in the automotive, industrial a...

UV and ambient light-induced modifications and related degradation of therapeutic proteins are observed during manufacturing and storage. Therefore, to ensure product quality, protein formulations need to be analyzed with respect to photo-degradation...

Finite difference methods are commonly used in the pricing of discretely monitored exotic options in the Black–Scholes framework, but they tend to converge slowly due to discontinuities contained in terminal conditions. We present an effective...

The ATPase Family, AAA domain-containing protein 2 (ATAD2) bromodomain (BRD) has a canonical bromodomain structure consisting of four α-helices. ATAD2 functions as a co-activator of the androgen and estrogen receptors as well as the MYC and E2F trans...

The current load distribution model for cycloid drives based on the Hertz contact stiffness typically assumes a two-dimensional planar problem without considering the tooth longitudinal modification effects, which fails to comply with the practical s...

In the present study, indium tin oxide (ITO) was used as a transparent working electrode for the development of an electrochemical sensor for the detection of mercury (II) ions (Hg²⁺). The electrode was modified by direct electrodeposition of polyani...

The following article: doi:10.3390/app2010035 [1] has been retracted by the author due to problems in the hydrocode simulation configuration.

The influence of stable-to-self-condensation Cu(II)-coordinated polyoxyethylene-substituted silicas (ASiP-Cu-0.5) on the synthesis of microporous block copolymers (OBCs) whose structural feature is the existence of coplanar polyisocyanate blocks of a...

We have synthesized cubic and linear polysiloxanes containing polyoxyethylene branches (ASiP-Cu) using tetraethoxysilane, polyoxyethylene glycol, and copper chloride as precursors; the products are stable to self-condensation. The effect of copper ch...

Polydimethylsiloxane (PDMS) is ubiquitously used in microfluidics. However, PDMS is porous and hydrophobic, potentially leading to small molecule partitioning. Although many studies addressed this issue and suggested surface/bulk modifications to ove...

Wood fiber and its products are modified to increase fire and bio-resistance. The best results are achieved by using modifiers that enter into chemical interaction with the hydroxylated substrate, forming the organic matrix of the materials. The purp...

Due to long-term operation under low-speed and heavy-load conditions, large module gears and racks are inevitably subject to tooth surface wear. To investigate the changes in gear tooth bending strength, the Three Gorges ship lift was taken as the re...

Silicone implants are widely used in medical applications, particularly for breast augmentation and reconstruction. However, ongoing concerns regarding their long-term safety and biocompatibility necessitate comprehensive characterization. This revie...

The incorporation of a proper sensing material towards the construction of high selectivity optical sensing devices is vital. Polysaccharides, such as chitosan and carrageenan, are among the bio-based sensing materials that are extensively employed d...

Oxidative modifications of HDLs and LDLs by myeloperoxidase (MPO) are regularly mentioned in the context of atherosclerosis. The enzyme adsorbs on protein moieties and locally produces oxidizing agents to modify specific residues on apolipoproteins A...

Mass spectrometry-based analysis of post-translational modifications (PTMs) is a key strategy for characterizing protein regulation and identifying disease-associated targets, with endogenous PTMs serving as biomarkers for disease diagnosis and thera...

N¹-methyladenosine (m¹A) is a prevalent and reversible post-transcriptional RNA modification that decorates tRNA, rRNA and mRNA. Recent studies based on technical advances in analytical chemistry and high-throughput sequencing methods have revealed t...

Monoclonal antibodies (mAbs) are a fast-growing class of biopharmaceuticals. They are widely used in the identification and detection of cell makers, serum analytes, and pathogenic agents, and are remarkably used for the cure of autoimmune diseases,...

Protein S-glutathionylation (SSG) is a reversible post-translational modification (PTM) featuring the conjugation of glutathione to a protein cysteine thiol. SSG can alter protein structure, activity, subcellular localization, and interaction with sm...

New analytics of post-transcriptional RNA modifications have paved the way for a tremendous upswing of the biological and biomedical research in this field. This especially applies to methods that included RNA-Seq techniques, and which typically resu...

Vortex shedding phenomenon behind bluff bodies and its destructive unsteady wake can be controlled by employing active and passive flow control methods. In this quest, researchers employed experimental fluid dynamics (EFD), computational fluid dynami...

Impurity doping is one of the common approaches to enhance the photoactivity of semiconductor nanomaterials by increasing photon-capture efficiency in the visible light range. However, many studies on the doping effects have produced inconclusive and...

One of the primary challenges regarding chronic kidney disease (CKD) diagnosis is the absence of reliable methods to detect early-stage kidney damage. A metabolomic approach is expected to broaden the current diagnostic modalities by enabling timely...

Perovskite nanostructures are promising nanomaterials for their possible application in electrochemiluminescent (ECL) analytical systems due to their unique optical, electronic, and chemical properties. This review focuses on the most recent advances...

Mass spectrometry has become an indispensable tool for the identification and quantification of epigenetic modifications, offering both high sensitivity and structural specificity. The two major classes of epigenetic modifications identified—DN...

Aptamers are short single stranded DNA or RNA oligonucleotides that can recognize analytes with extraordinary target selectivity and affinity. Despite their promising properties and diagnostic potential, the number of commercial applications remains...

RNA modifications, particularly N6-methyladenosine (m6A), are pivotal regulators of RNA functionality and cellular processes. We analyzed m6A modifications by employing Oxford Nanopore technology and the m6Anet algorithm, focusing on the HepG2 cell l...

In this work, a screening of Sonogel-Carbon (SNGC) electrodes modified with nanomaterials (carbon nanotubes and gold nanoparticles) and the study of their effect on the electrochemical performance of sinusoidal voltage (SV) and current (SC)-based bio...

The magnetic acceleration noise (MAN) that stems from the eddy current dissipation of a test mass (TM) serves as an important source of noise for space inertial sensors. Given the problem that the eddy current dissipation magnetic acceleration noise...

Protein modifications, particularly post-translational modifications (PTMs) such as phosphorylation and glycosylation, are fundamental mechanisms regulating cellular activity and disease pathogenesis, with their detection emerging as a promising fron...

Bevacizumab is a humanized therapeutic monoclonal antibody used to reduce angiogenesis, a hallmark of cancer, by binding to VEGF-A. Many pharmaceutical companies have developed biosimilars of Bevacizumab in the last decade. The official reports provi...

Nowadays, foodborne pathogens and other food contaminants are among the major contributors to human illnesses and even deaths worldwide. There is a growing need for improvements in food safety globally. However, it is a challenge to detect and identi...

RNA modifications are essential regulators of gene expression and cellular function, modulating RNA stability, splicing, translation, and localization. Dysregulation of these modifications has been linked to cancer, neurodegenerative disorders, viral...

Biosensors are analytical devices that use biological interactions to detect and quantify single molecules, clinical biomarkers, contaminants, allergens, and microorganisms. By coupling bioreceptors with transducers, such as nucleic acids or proteins...

Time-varying mesh stiffness (TVMS) of the internal mesh transmission is a significant source of excitation that causes vibration and noise in planetary gear systems, and is also an important parameter in dynamics analysis. Currently, the calculation...

There is presented an overview of the latest advances in the analytical theory of Stark broadening of hydrogenic spectral lines in various types of laboratory and astrophysical plasmas. They include: (1) advanced analytical treatment of the Stark bro...

Rosin, a renewable natural resin derived from pine trees, is a promising biomass material for sustainable product development, though its distinct intrinsic odor limits broader use. This study implemented a comprehensive analytical strategy to mitiga...

In this paper, the integrability of a nonlinear system developing endemic Malaria was demonstrated using Prelle–Singer techniques. In addition, Lie symmetry techniques were employed to identify additional independent variables that led to the m...

This paper presents mixed analytical/numerical method for estimating the static top-to-bottom compressive strength of corrugated packaging with different ventilation openings and holes, in which the torsional and shear stiffness of corrugated cardboa...

Molecular mechanisms underlying health and disease function at least in part based on the flexibility and fine-tuning afforded by protein isoforms and post-translational modifications. The ability to effectively and consistently resolve these protein...

Magnetic beads (MBs) are versatile tools for the purification, detection, and quantitative analysis of analytes from complex matrices. The superparamagnetic property of magnetic beads qualifies them for various analytical applications. To provide spe...

Optical detection devices have become an analytical tool of interest in diverse fields of science. The search for methods to identify and quantify different compounds has transposed this curiosity into a necessity, since some constituents threaten th...

Electrospun polymer membranes are regarded as prospective biosensor components due to their large specific surface area and diverse opportunities for chemical modifications. However, their intricate porous structure can impede diffusion and render so...

Many-core system-on-chips, together with their established communication infrastructures, Networks-on-Chip (NoC), are growing in complexity, which encourages the integration of third-party components to simplify and accelerate production processes. H...