Throughout the vegetable oil industry, there is a focus on eradicating the volatile molecules affecting the aroma or taste of the crude oil, whether it is natural or derived from the extraction process. Refining aims to reduce these compounds to a le...
Porphyromonas gingivalis Mfa1 fimbriae are thought to act as adhesion factors and to direct periodontal tissue destruction but their immunomodulatory actions are poorly understood. Here, we investigated the effect of Mfa1 stimulation on the immune an...
Phosphodiesterase-4 (PDE4) plays an important role in treatment of asthma andchronic obstructive pulmonary disease. Thirty-one analogs displaying variable inhibition ofPDE4 were selected to develop models for establishing three-dimensional quantitati...
Authentication mechanisms attract considerable research interest due to the protective role they offer, and when they fail, the system becomes vulnerable and immediately exposed to attacks. Blockchain technology was recently incorporated to enhance a...
Kinase insert domain receptor (KDR) inhibitors have been proved to be very effective anticancer agents. Molecular docking, 3D-QSAR methods, CoMFA and CoMSIA were performed on pyrrolo[3,2-d]pyrimidine derivatives as non-ATP competitive KDR inhibitors...
A 3D-QSAR (CoMFA) study was performed in an extensive series of aminoalkylindoles derivatives with affinity for the cannabinoid receptors CB1 and CB2. The aim of the present work was to obtain structure-activity relationships of the aminoalkylindole...
Selective S1P1 receptor agonists have therapeutic potential to treat a variety of immune-mediated diseases. A series of 2-imino-thiazolidin-4-one derivatives displaying potent S1P1 receptor agonistic activity were selected to establish 3D-QSAR models...
After a hierarchical microbial screening process, new microorganisms have been discovered that act as biocatalysts for the stereoselective oxidation of secondary alcohols or for ketone reduction. Oxidation activity is more widespread in yeasts and ba...
Increasing evidence has shown collagen hydrolysate involves a variety of bioactivities. In our previous study, multiple antiplatelet peptides containing Hyp/Pro-Gly were identified in collagen hydrolysates from Salmo salar and silver carp skin and ex...
Indoor localization is a dynamic and exciting research area. WiFi has exhibited a tremendous capability for internal localization since it is extensively used and easily accessible. Facilitating the use of WiFi for this purpose requires fingerprint f...
Recently, research using point clouds has been increasing with the development of 3D scanner technology. According to this trend, the demand for high-quality point clouds is increasing, but there is still a problem with the high cost of obtaining hig...
This paper reviews around 41 articles providing the trends, characteristics, research gaps and challenges of these studies that may help e-waste management-related academics and practitioners with an overview of the need for such tool to be applied....
The α1A-adrenergic receptor (α1A-AR) antagonist is useful in treating benign prostatic hyperplasia, lower urinary tract symptoms, and cardiac arrhythmia. Three-dimensional quantitative structure-activity relationship (3D-QSAR) studies were performed...
Deep-learning-based methods are crucial for building extraction from high-resolution remote sensing images, playing a key role in applications like natural disaster response, land resource management, and smart city development. However, extracting p...
In the present study, we have employed the ligand-based drug design technique, 3D-QSAR, through a comparative molecular field analysis (CoMFA) and a comparative molecular similarity indices analysis (CoMSIA) to determine the key factors for the plant...
Semantic Change Detection (SCD) in remote sensing imagery is a common technique for monitoring surface dynamics. However, geospatial data acquisition increasingly involves the collection of visible and infrared images. SCD in visible and infrared ima...
The wide tissue distribution of the adrenergic β3 receptor makes it a potential target for the treatment of multiple pathologies such as diabetes, obesity, depression, overactive bladder (OAB), and cancer. Currently, there is only one drug on th...
Dynamic hand gesture recognition has attracted increasing attention because of its importance for human–computer interaction. In this paper, we propose a novel motion feature augmented network (MFA-Net) for dynamic hand gesture recognition from...
Industrial metabolism is a recent field of research in engineering and sustainability. Its practical objective is to provide structural solutions to organizations and regulate the productive, ecological, and economic system. Due to being a relatively...
CoMFA, CoMSIA and eigenvalue analysis (EVA) were performed to study the structural features of 61 diverse dibenzodioxepinone and dibenzodioxocinone analogues to probe cholesteryl ester transfer protein (CETP) inhibitory activity. Three methods yielde...
Betulinic acid (BA) is a natural product that exerts its cytotoxicity against various malignant carcinomas without side effects by triggering the mitochondrial pathway to apoptosis. Betulin (BE), the 28-hydroxyl analog of BA, is present in large amou...
This paper assesses world-wide patterns of material extraction, trade, consumption and productivity based on a new data set for economy-wide material flows, covering used materials for all countries world-wide between 1980 and 2009. We show that glob...
Cellulose fiber is a tremendous natural resource that has broad application in various productions including the textile industry. The dyes, which are commonly used for cellulose printing, are “reactive dyes” because of their high wet fastness and br...
Human pose estimation in factory surveillance is challenged by scale variation, limb occlusion, complex backgrounds, and spatial detail loss during upsampling. This paper proposes MFA-Pose, an improved YOLO11s-Pose framework that enhances contextual...
The large-scale integration of wind and solar photovoltaic (PV) power is a cornerstone of low-carbon, sustainable energy systems. However, the uncertainty of the output brings great challenges to the operation and dispatching of power systems. To cle...
Triple-negative breast cancer (TNBC) is defined as a kind of breast cancer that lacks estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor receptors (HER2). This cancer accounts for 10–15% of all breast cancer...
In the modern digital era, everyone is partially or fully integrated with cloud computing to access numerous cloud models, services, and applications. Multi-cloud is a blend of a well-known cloud model under a single umbrella to accomplish all the di...
This article uses the rice price crisis of 2007–2008 to show how material flow analysis (MFA) can be combined with resilience research. After presentation of fundamental information and methods, resilience-related concepts are illustrated using graph...
Medical image segmentation acts as a foundational element of medical image analysis. Yet its accuracy is frequently limited by the scale fluctuations of anatomical targets and the intricate contextual traits inherent in medical images—including...
The effect of Mfa1 fimbriae of Porphyromonas gingivalis on the progression of bone resorption remains unclear, especially compared with another fimbriae, FimA. We investigated the effect of Mfa1 on osteoclastogenesis together with FimA. We also inves...
In this study, magnetic fly ash was prepared with fly ash and nano-magnetic Fe3O4, obtained by co-precipitation. Then, a magnetic fly ash/polydimethylsiloxane (MFA@PDMS) sponge was prepared via simple dip-coating PDMS containing ethanol in magnetic f...
Metabolic flux analysis (MFA) is an increasingly important tool to study metabolism quantitatively. Unlike the concentrations of metabolites, the fluxes, which are the rates at which intracellular metabolites interconvert, are not directly measurable...
Background/Objectives: It has become a major direction of research in affective computing to explore the brain-information-processing mechanisms based on physiological signals such as electroencephalography (EEG) and functional near-infrared spectros...
Selective cyclooxygenase inhibitors have attracted much attention in recent times in the design of new non-steroidal anti-inflammatory drugs (NSAID). 3D-QSAR studies have been performed on a series of 1,5-diarylpyrazoles that act as selective cycloox...
Material Flow Analysis (MFA) is a key tool in the circular bioeconomy, providing insight into the flow of materials within a system. Its use in the wood-based value chain is increasingly recognized and provides valuable information for policy making....
The three-dimensional quantitative structure–activity relationship (3D-QSAR) and pharmacophore identification studies on 28 substituted benzoxazinone derivatives as antiplatelet agents have been carried out. Multiple linear regression (MLR) method wa...
Through combining P-type iterative learning (IL) control, model-free adaptive (MFA) control and sliding mode (SM) control, a robust model-free adaptive iterative learning (MFA-IL) control approach is presented for the active vibration control of piez...
This work aimed to construct 3D-QSAR CoMFA and CoMSIA models for a series of 31 FAAH inhibitors, containing the 1,3,4-oxadiazol-2-one moiety. The obtained models were characterized by good statistical parameters: CoMFA Q2 = 0.61, R2 = 0.98; CoMSIA Q2...
Multi-factor authentication (MFA) is a system for authenticating an individual’s identity using two or more pieces of data (known as factors). The reason for using more than two factors is to further strengthen security through the use of addit...
In order to search for novel antipsychotics acting through the D2 receptor, it is necessary to know the structure–activity relationships for dopamine D2 receptor antagonists. In this context, we constructed the universal three-dimensional quant...
Aromatase inhibitors are the most important targets in treatment of estrogen-dependent cancers. In order to search for potent steroidal aromatase inhibitors (SAIs) with lower side effects and overcome cellular resistance, comparative molecular field...
Micro-Fabric Analyzer (MFA) is a new GIS-based tool for the quantitative extrapolation of rock microstructural features that takes advantage both of the characteristics of the X-ray images and the optical image features. Most of the previously develo...
A computational strategy based on comparative molecular fields analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) was performed on a series of the 11H-dibenz[b,e]azepine and dibenz[b,f][1,4]oxazepine derivatives as potent...
Urease enzyme (EC 3.5.1.5) has been determined as a virulence factor in pathogenic microorganisms that are accountable for the development of different diseases in humans and animals. In continuance of our earlier study on the helicobacter pylori ure...
Today, digitalization decisively penetrates all the sides of the modern society. One of the key enablers to maintain this process secure is authentication. It covers many different areas of a hyper-connected world, including online payments, communic...
CDK2/cyclin A has appeared as an attractive drug targets over the years with diverse therapeutic potentials. A computational strategy based on comparative molecular fields analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA...
The overwhelming popularity of technology-based solutions and innovations to address day-to-day processes has significantly contributed to the emergence of smart cities. where millions of interconnected devices and sensors generate and share huge vol...
Aurora kinases have emerged as attractive targets for the design of anticancer drugs. 3D-QSAR (comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA)) and Surflex-docking studies were performed on...
Janus kinase 2 (JAK2) is an intracellular nonreceptor tyrosine kinase that belongs to the JAK family of kinases, which play an important role in survival, proliferation, and differentiation of a variety of cells. JAK2 inhibitors are potential drugs f...
Wood and wood-based products are increasingly recognized for their renewability and carbon storage capacity, supporting sustainable development and circular economy goals in the EU. This paper provides a comprehensive review of 42 material flow analy...
of 10