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437 Results Found

  • Article
  • Open Access
2,009 Views
20 Pages

After the attempt at collaboration between the Frankfurt School and the Vienna Circle failed in the late 1930s, Adorno stood at the forefront of critical theory’s polemics against ‘positivism’. Given these later polemical exchanges,...

  • Editorial
  • Open Access
23 Citations
3,769 Views
5 Pages

14 November 2017

Inflammation is the body’s response to injury or infection. As early as 2000 years ago, the Roman encyclopaedist Aulus Cornelius Celsus recognised four cardinal signs of this response—redness, heat, swelling and pain; a fifth sign is loss of function...

  • Article
  • Open Access
71 Citations
52,302 Views
15 Pages

Does Dietary Fiber Affect the Levels of Nutritional Components after Feed Formulation?

  • Seidu Adams,
  • Cornelius Tlotliso Sello,
  • Gui-Xin Qin,
  • Dongsheng Che and
  • Rui Han

7 May 2018

Studies on dietary fiber and nutrient bioavailability have gained an increasing interest in both human and animal nutrition. Questions are increasingly being asked regarding the faith of nutrient components such as proteins, minerals, vitamins, and l...

  • Article
  • Open Access
13 Citations
10,219 Views
35 Pages

A Promising PET Tracer for Imaging of α7 Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand

  • Rodrigo Teodoro,
  • Matthias Scheunemann,
  • Winnie Deuther-Conrad,
  • Barbara Wenzel,
  • Francesca Maria Fasoli,
  • Cecilia Gotti,
  • Mathias Kranz,
  • Cornelius K. Donat,
  • Marianne Patt and
  • Ansel Hillmer
  • + 6 authors

9 October 2015

Changes in the expression of α7 nicotinic acetylcholine receptors (α7 nAChRs) in the human brain are widely assumed to be associated with neurological and neurooncological processes. Investigation of these receptors in vivo depends on the availabilit...

  • Review
  • Open Access
131 Citations
15,929 Views
18 Pages

Desmoplasia and Chemoresistance in Pancreatic Cancer

  • Marvin Schober,
  • Ralf Jesenofsky,
  • Ralf Faissner,
  • Cornelius Weidenauer,
  • Wolfgang Hagmann,
  • Patrick Michl,
  • Rainer L. Heuchel,
  • Stephan L. Haas and
  • J.-Matthias Löhr

21 October 2014

Pancreatic ductal adenocarcinoma (PDAC) occurs mainly in people older than 50 years of age. Although great strides have been taken in treating PDAC over the past decades its incidence nearly equals its mortality rate and it was quoted as the 4th lea...

  • Article
  • Open Access
71 Citations
10,869 Views
19 Pages

Estimating Fractional Shrub Cover Using Simulated EnMAP Data: A Comparison of Three Machine Learning Regression Techniques

  • Marcel Schwieder,
  • Pedro J. Leitão,
  • Stefan Suess,
  • Cornelius Senf and
  • Patrick Hostert

22 April 2014

Anthropogenic interventions in natural and semi-natural ecosystems often lead to substantial changes in their functioning and may ultimately threaten ecosystem service provision. It is, therefore, necessary to monitor these changes in order to unders...

  • Article
  • Open Access
40 Citations
14,751 Views
31 Pages

Changing the Environment Based on Empowerment as Intrinsic Motivation

  • Christoph Salge,
  • Cornelius Glackin and
  • Daniel Polani

21 May 2014

One aspect of intelligence is the ability to restructure your own environment so that the world you live in becomes more beneficial to you. In this paper we investigate how the information-theoretic measure of agent empowerment can provide a task-ind...

  • Article
  • Open Access
19 Citations
8,926 Views
26 Pages

Location Privacy for Mobile Crowd Sensing through Population Mapping

  • Minho Shin,
  • Cory Cornelius,
  • Apu Kapadia,
  • Nikos Triandopoulos and
  • David Kotz

29 June 2015

Opportunistic sensing allows applications to “task” mobile devices to measure context in a target region. For example, one could leverage sensor-equipped vehicles to measure traffic or pollution levels on a particular street or users’ mobile phones t...

  • Article
  • Open Access
5 Citations
5,759 Views
10 Pages

Enumeration of Somatic and F-RNA Phages as an Indicator of Fecal Contamination in Potable Water from Rural Areas of the North West Province

  • Keitumetse Idah Nkwe,
  • Collins Njie Ateba,
  • Nomathamsanqa Patricia Sithebe and
  • Cornelius Carlos Bezuidenhout

1 July 2015

Bacteriophages are regarded as enteric viral indicators in faecally contaminated water systems and may indicate the presence of human viral pollution. They are relatively resistant to inactivation by natural and treatment processes. In this study, th...

  • Article
  • Open Access
22 Citations
6,868 Views
17 Pages

Coordination of Candida albicans Invasion and Infection Functions by Phosphoglycerol Phosphatase Rhr2

  • Jigar V. Desai,
  • Shaoji Cheng,
  • Tammy Ying,
  • M. Hong Nguyen,
  • Cornelius J. Clancy,
  • Frederick Lanni and
  • Aaron P. Mitchell

24 July 2015

The Candida albicans RHR2 gene, which specifies a glycerol biosynthetic enzyme, is required for biofilm formation in vitro and in vivo. Prior studies indicate that RHR2 is ultimately required for expression of adhesin genes, such as ALS1. In fact, RH...

  • Article
  • Open Access
30 Citations
7,339 Views
13 Pages

Aminolevulinic Acid-Mediated Photodynamic Therapy of Human Meningioma: An in Vitro Study on Primary Cell Lines

  • Mustafa El-Khatib,
  • Carolin Tepe,
  • Brigitte Senger,
  • Maxine Dibué-Adjei,
  • Markus Johannes Riemenschneider,
  • Walter Stummer,
  • Hans Jakob Steiger and
  • Jan Frédérick Cornelius

30 April 2015

Objective: Five-aminolevulinic acid (5-ALA)-induced porphyrins in malignant gliomas are potent photosensitizers. Promising results of ALA-PDT (photodynamic therapy) in recurrent glioblastomas have been published. Recently, 5-ALA-induced fluorescence...

  • Article
  • Open Access
39 Citations
7,786 Views
22 Pages

7 May 2015

Due to modern life with increasing traffic, industrial production and agricultural practices, high amounts of heavy metals enter ecosystems and pollute soil and water. As a result, metals can be accumulated in plants and particularly in algae inhabi...

  • Article
  • Open Access
152 Citations
72,376 Views
27 Pages

Impact of Population Growth and Climate Change on the Freshwater Resources of Lamu Island, Kenya

  • Cornelius Okello,
  • Bruno Tomasello,
  • Nicolas Greggio,
  • Nina Wambiji and
  • Marco Antonellini

18 March 2015

Demand for freshwater is rising with factors, such as population growth, land use change and climate variations, rendering water availability in the future uncertain. Groundwater resources are being increasingly exploited to meet this growing demand...

  • Review
  • Open Access
391 Views
18 Pages

Immune Cells in Preeclampsia

  • Nathan Campbell,
  • Marcus Robbins,
  • Hellen Nembaware,
  • Evangeline Deer,
  • Denise Cornelius and
  • Babbette LaMarca

Preeclampsia (PE), new-onset hypertension during pregnancy, is associated with chronic inflammation both in the placenta and systemically. PE is characterized by placental ischemia, which then results in the production and release of anti-angiogenic...

  • Article
  • Open Access
250 Views
18 Pages

Characterization and Antimicrobial Assessment of Cadmium Sulfide Nanoparticles

  • Ezinne Uchechi Ekwujuru,
  • Moses Gbenga Peleyeju,
  • Cornelius Ssemakalu,
  • Mzimkhulu Monapathi and
  • Michael Klink

31 December 2025

Resistance to conventional antibiotics remains a global health challenge. The search for more effective antimicrobial agents has led to the consideration of nanoparticles due to their potential biocidal activities. This study synthesized, characteriz...

  • Correction
  • Open Access
241 Views
1 Page

Correction: Növer et al. Prediction of Recurrence and Rupture Risk of Ruptured and Unruptured Intracranial Aneurysms of the Posterior Circulation: A Machine Learning-Based Analysis. Diagnostics 2025, 15, 2365

  • Martin Növer,
  • Hanna Styczen,
  • Ramazan Jabbarli,
  • Philipp Dammann,
  • Martin Köhrmann,
  • Tim Hagenacker,
  • Christoph Moenninghoff,
  • Michael Forsting,
  • Yan Li and
  • Isabel Wanke
  • + 2 authors

21 November 2025

In the original publication [...]

  • Article
  • Open Access
682 Views
40 Pages

21 November 2025

Aflatoxins (Afs) belong to the most hazardous mycotoxins. Their detrimental effects on humans and higher animals are widely known, and actions are poised to avoid their synthesis already in the developing plant. However, this is often not effective e...

  • Article
  • Open Access
1,495 Views
15 Pages

26 November 2025

This work constructs a new mathematical model for the vibrations of a Bernoulli beam that can come in contact with a reactive obstacle situated below its right end. The obstacle reaction is described by the Damped Normal Compliance (DNC) contact cond...

  • Article
  • Open Access
11 Citations
6,326 Views
11 Pages

23 March 2012

This study examines the individual behavior of workers of the Formosan subterranean termite, Coptotermes formosanus Shirkai, on two consecutive days of tunnel construction. In each trial, a group of 30 termite workers was observed continuously during...

  • Review
  • Open Access
11 Citations
5,645 Views
11 Pages

6 February 2016

Mortality rates due to invasive candidiasis remain unacceptably high, in part because the poor sensitivity and slow turn-around time of cultures delay the initiation of antifungal treatment. β-d-glucan (Fungitell) and polymerase chain reaction (PCR)-...

  • Article
  • Open Access
42 Citations
11,888 Views
14 Pages

Relationship between Serum Omega-3 Fatty Acid and Asthma Endpoints

  • Shahieda Adams,
  • Andreas L. Lopata,
  • Cornelius M. Smuts,
  • Roslynn Baatjies and
  • Mohamed F. Jeebhay

Recent studies have highlighted the potential protective role of omega-3 polyunsaturated fatty acids (n-3 PUFA) in asthma. This study aimed at determining the association between seafood intake, serum PUFA composition and clinical endpoints of asthma...

  • Project Report
  • Open Access
5 Citations
6,280 Views
10 Pages

Botswana has the third highest rate of HIV infection, as well as one of the highest mobile phone density rates in the world. The rate of mobile cell phone adoption has increased three-fold over the past 10 years. Due to HIV infection rates, youth and...

  • Article
  • Open Access
110 Citations
27,479 Views
57 Pages

Fischer–Tropsch: Product Selectivity–The Fingerprint of Synthetic Fuels

  • Wilson D. Shafer,
  • Muthu Kumaran Gnanamani,
  • Uschi M. Graham,
  • Jia Yang,
  • Cornelius M. Masuku,
  • Gary Jacobs and
  • Burtron H. Davis

14 March 2019

The bulk of the products that were synthesized from Fischer–Tropsch synthesis (FTS) is a wide range (C1–C70+) of hydrocarbons, primarily straight-chained paraffins. Additional hydrocarbon products, which can also be a majority, are linear olefins, sp...

  • Article
  • Open Access
13 Citations
3,999 Views
11 Pages

Caprate Modulates Intestinal Barrier Function in Porcine Peyer’s Patch Follicle-Associated Epithelium

  • Judith Radloff,
  • Valeria Cornelius,
  • Alexander G. Markov and
  • Salah Amasheh

Background: Many food components influence intestinal epithelial barrier properties and might therefore also affect susceptibility to the development of food allergies. Such allergies are triggered by increased antibody production initiated in Peyer&...

  • Review
  • Open Access
906 Citations
82,097 Views
30 Pages

Blockchain Technology in Healthcare: A Systematic Review

  • Cornelius C. Agbo,
  • Qusay H. Mahmoud and
  • J. Mikael Eklund

Since blockchain was introduced through Bitcoin, research has been ongoing to extend its applications to non-financial use cases. Healthcare is one industry in which blockchain is expected to have significant impacts. Research in this area is relativ...

  • Article
  • Open Access
24 Citations
5,174 Views
18 Pages

Biomechanical Evaluation of Promising Different Bone Substitutes in a Clinically Relevant Test Set-Up

  • Theresa Brueckner,
  • Philipp Heilig,
  • Martin Cornelius Jordan,
  • Mila Marie Paul,
  • Torsten Blunk,
  • Rainer Heribert Meffert,
  • Uwe Gbureck and
  • Stefanie Hoelscher-Doht

26 April 2019

(1) Background: Bone substitutes are essential in orthopaedic surgery to fill up large bone defects. Thus, the aim of the study was to compare diverse bone fillers biomechanically to each other in a clinical-relevant test set-up and to detect differe...

  • Article
  • Open Access
18 Citations
6,319 Views
17 Pages

Combination of River Bank Filtration and Solar-driven Electro-Chlorination Assuring Safe Drinking Water Supply for River Bound Communities in India

  • Philipp Otter,
  • Pradyut Malakar,
  • Cornelius Sandhu,
  • Thomas Grischek,
  • Sudhir Kumar Sharma,
  • Prakash Chandra Kimothi,
  • Gabriele Nüske,
  • Martin Wagner,
  • Alexander Goldmaier and
  • Florian Benz

11 January 2019

The supply of safe drinking water in rural developing areas is still a matter of concern, especially if surface water, shallow wells, and wells with non-watertight headworks are sources for drinking water. Continuously changing raw water conditions,...

  • Review
  • Open Access
134 Citations
23,149 Views
40 Pages

Applying the Smart Grid Architecture Model for Designing and Validating System-of-Systems in the Power and Energy Domain: A European Perspective

  • Mathias Uslar,
  • Sebastian Rohjans,
  • Christian Neureiter,
  • Filip Pröstl Andrén,
  • Jorge Velasquez,
  • Cornelius Steinbrink,
  • Venizelos Efthymiou,
  • Gianluigi Migliavacca,
  • Seppo Horsmanheimo and
  • Helfried Brunner
  • + 1 author

15 January 2019

The continuously increasing complexity of modern and sustainable power and energy systems leads to a wide range of solutions developed by industry and academia. To manage such complex system-of-systems, proper engineering and validation approaches, m...

  • Article
  • Open Access
7 Citations
3,600 Views
12 Pages

It’s about Time: Effects of Physical Exertion on Duration Estimates

  • Britton W. Brewer,
  • Lawrence O. Schwartz,
  • Allen E. Cornelius,
  • Judy L. Van Raalte,
  • Edmundo L. Urbina and
  • John S. Stubbs

Background: Task duration is a fundamental aspect of exercise, but little is known about how completed bouts of physical activity are perceived. Consequently, the purpose of the five experiments conducted for this investigation was to examine the eff...

  • Article
  • Open Access
37 Citations
10,180 Views
17 Pages

23 May 2018

In the context of increasing climate-related extreme events and other crises, the concept of adaptive social protection (ASP) has been recognized as a potentially effective policy response to reduce the impacts of these shocks and stressors on vulner...

  • Article
  • Open Access
12 Citations
4,300 Views
16 Pages

De Novo Assembly and Comparative Transcriptome Profiling of Anser anser and Anser cygnoides Geese Species’ Embryonic Skin Feather Follicles

  • Cornelius Tlotliso Sello,
  • Chang Liu,
  • Yongfeng Sun,
  • Petunia Msuthwana,
  • Jingtao Hu,
  • Yujian Sui,
  • Shaokang Chen,
  • Yuxuan Zhou,
  • Hongtao Lu and
  • Chenguang Xu
  • + 4 authors

8 May 2019

Geese feather production and the quality of downy feathers are additional economically important traits in the geese industry. However, little information is available about the molecular mechanisms fundamental to feather formation and the quality of...

  • Article
  • Open Access
20 Citations
5,590 Views
17 Pages

A Water Quality Appraisal of Some Existing and Potential Riverbank Filtration Sites in India

  • Cornelius Sandhu,
  • Thomas Grischek,
  • Hilmar Börnick,
  • Jörg Feller and
  • Saroj Kumar Sharma

28 January 2019

There is a nationwide need among policy and decision makers and drinking water supply engineers in India to obtain an initial assessment of water quality parameters for the selection and subsequent development of new riverbank filtration (RBF) sites....

  • Article
  • Open Access
8 Citations
5,836 Views
13 Pages

Intrinsic Flexibility of the EMT Zeolite Framework under Pressure

  • Antony Nearchou,
  • Mero-Lee U. Cornelius,
  • Jonathan M. Skelton,
  • Zöe L. Jones,
  • Andrew B. Cairns,
  • Ines E. Collings,
  • Paul R. Raithby,
  • Stephen A. Wells and
  • Asel Sartbaeva

12 February 2019

The roles of organic additives in the assembly and crystallisation of zeolites are still not fully understood. This is important when attempting to prepare novel frameworks to produce new zeolites. We consider 18-crown-6 ether (18C6) as an additive,...

  • Article
  • Open Access
2 Citations
5,938 Views
21 Pages

Natural Formation of Chloro- and Bromoacetone in Salt Lakes of Western Australia

  • Tobias Sattler,
  • Matthias Sörgel,
  • Julian Wittmer,
  • Efstratios Bourtsoukidis,
  • Torsten Krause,
  • Elliot Atlas,
  • Simon Benk,
  • Sergej Bleicher,
  • Katharina Kamilli and
  • Johannes Ofner
  • + 6 authors

30 October 2019

Western Australia is a semi-/arid region known for saline lakes with a wide range of geochemical parameters (pH 2.5–7.1, Cl− 10–200 g L−1). This study reports on the haloacetones chloro- and bromoacetone in air over 6 salt lak...

  • Article
  • Open Access
20 Citations
6,534 Views
21 Pages

Neutrophil Maturation and Survival Is Controlled by IFN-Dependent Regulation of NAMPT Signaling

  • Elena Siakaeva,
  • Ekaterina Pylaeva,
  • Ilona Spyra,
  • Sharareh Bordbari,
  • Benedikt Höing,
  • Cornelius Kürten,
  • Stephan Lang and
  • Jadwiga Jablonska

8 November 2019

Granulocyte-colony stimulating factor (G-CSF)/nicotinamide phosphoribosyltransferase (NAMPT) signaling has been shown to be crucial for the modulation of neutrophil development and functionality. As this signaling pathway is significantly suppressed...

  • Article
  • Open Access
7 Citations
3,603 Views
13 Pages

20 December 2019

Management practices that promote dual-purpose use of cover crops as forage and soil cover can encourage adoption in mixed smallholder (SH) farming systems. This study investigated the feasibility of dual-purpose use of forage sorghum (Sorghum bicolo...

  • Article
  • Open Access
16 Citations
4,862 Views
18 Pages

The First Glimpse of Streptocarpus ionanthus (Gesneriaceae) Phylogenomics: Analysis of Five Subspecies’ Chloroplast Genomes

  • Cornelius M. Kyalo,
  • Zhi-Zhong Li,
  • Elijah M. Mkala,
  • Itambo Malombe,
  • Guang-Wan Hu and
  • Qing-Feng Wang

4 April 2020

Streptocarpus ionanthus (Gesneriaceae) comprise nine herbaceous subspecies, endemic to Kenya and Tanzania. The evolution of Str. ionanthus is perceived as complex due to morphological heterogeneity and unresolved phylogenetic relationships. Our study...

  • Article
  • Open Access
9 Citations
3,575 Views
17 Pages

Activin A-Mediated Regulation of XT-I in Human Skin Fibroblasts

  • Thanh-Diep Ly,
  • Ricarda Plümers,
  • Bastian Fischer,
  • Vanessa Schmidt,
  • Doris Hendig,
  • Joachim Kuhn,
  • Cornelius Knabbe and
  • Isabel Faust

14 April 2020

Fibrosis is a fundamental feature of systemic sclerosis (SSc) and is characterized by excessive accumulation of extracellular matrix components like proteoglycans (PG) or collagens in skin and internal organs. Serum analysis from SSc patients showed...

  • Article
  • Open Access
16 Citations
5,059 Views
13 Pages

Central Pathology Review in SENTIX, a Prospective Observational International Study on Sentinel Lymph Node Biopsy in Patients with Early-Stage Cervical Cancer (ENGOT-CX2)

  • Kristyna Nemejcova,
  • Roman Kocian,
  • Christhardt Kohler,
  • Jiri Jarkovsky,
  • Jaroslav Klat,
  • Alberto Berjon,
  • Radovan Pilka,
  • Borek Sehnal,
  • Blanca Gil-Ibanez and
  • Ezequiel Lupo
  • + 37 authors

29 April 2020

The quality of pathological assessment is crucial for the safety of patients with cervical cancer if pelvic lymph node dissection is to be replaced by sentinel lymph node (SLN) biopsy. Central pathology review of SLN pathological ultrastaging was con...

  • Article
  • Open Access
7 Citations
5,303 Views
13 Pages

Many tools for studying the pharmacokinetics of biologics lack single-cell resolution to quantify the heterogeneous tissue distribution and subsequent therapeutic degradation in vivo. This protocol describes a dual-labeling technique using two near-i...

  • Article
  • Open Access
23 Citations
6,435 Views
18 Pages

Are Battery-Electric Trucks for 24-Hour Delivery the Future of City Logistics?—A German Case Study

  • Cornelius Moll,
  • Patrick Plötz,
  • Karsten Hadwich and
  • Martin Wietschel

Especially in urban areas, a large proportion of air pollution can be attributed to road traffic. Thus, in many countries, bans are being discussed on diesel vehicles in inner cities. These diesel bans pose a severe threat to logistics service provid...

  • Article
  • Open Access
2 Citations
3,586 Views
21 Pages

Altered Cerebral Blood Flow and Potential Neuroprotective Effect of Human Relaxin-2 (Serelaxin) During Hypoxia or Severe Hypovolemia in a Sheep Model

  • René Schiffner,
  • Sabine J. Bischoff,
  • Thomas Lehmann,
  • Andrey Irintchev,
  • Marius Nistor,
  • Cornelius Lemke and
  • Martin Schmidt

27 February 2020

Specific neuroprotective strategies to minimize cerebral damage caused by severe hypoxia or hypovolemia are lacking. Based on previous studies showing that relaxin-2/serelaxin increases cortical cerebral blood flow, we postulated that serelaxin might...

  • Article
  • Open Access
16 Citations
5,013 Views
13 Pages

27 February 2020

In South Africa, haemoglobin (Hb) is measured to screen for iron deficiency (ID). However, low levels of Hb are only a late stage indicator of ID. Furthermore, Hb values are generally not adjusted for altitude even though recommended by WHO. We deter...

  • Article
  • Open Access
5 Citations
4,014 Views
6 Pages

Clinical Presentation of Community-Acquired Legionella Pneumonia Identified by Universal Testing in an Endemic Area

  • Shruti Puri,
  • Monique Boudreaux-Kelly,
  • Jon D. Walker,
  • Cornelius J. Clancy and
  • Brooke K. Decker

The rapid identification of Legionella pneumonia is essential to optimize patient treatment and outcomes, and to identify potential public health risks. Previous studies have identified clinical factors which are more common in Legionella than non-Le...

  • Article
  • Open Access
12 Citations
5,125 Views
19 Pages

In Vitro and In Vivo Characterization of Dibenzothiophene Derivatives [125I]Iodo-ASEM and [18F]ASEM as Radiotracers of Homo- and Heteromeric α7 Nicotinic Acetylcholine Receptors

  • Cornelius K. Donat,
  • Henrik H. Hansen,
  • Hanne D. Hansen,
  • Ronnie C. Mease,
  • Andrew G. Horti,
  • Martin G. Pomper,
  • Elina T. L’Estrade,
  • Matthias M. Herth,
  • Dan Peters and
  • Gitte M. Knudsen
  • + 1 author

20 March 2020

The α7 nicotinic acetylcholine receptor (α7 nAChR) is involved in several cognitive and physiologic processes; its expression levels and patterns change in neurologic and psychiatric diseases, such as schizophrenia and Alzheimer’s d...

  • Article
  • Open Access
11 Citations
5,813 Views
15 Pages

29 November 2019

China is fast becoming a coveted destination and a hub for higher education among international students, particularly since the announcement of its Belt and Road Initiative (BRI) in September 2013. Consequently, China’s higher-education instit...

  • Article
  • Open Access
11 Citations
6,588 Views
10 Pages

Effects of a Mental Warmup on the Workout Readiness and Stress of College Student Exercisers

  • Judy L. Van Raalte,
  • Britton W. Brewer,
  • Allen E. Cornelius,
  • Mary Keeler and
  • Christyan Gudjenov

The importance of warming up prior to sport competition has been highlighted in the scientific literature, with increasing attention paid to the benefits of mental warmups. The purpose of this research was to explore the possibility that a mental war...

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