Hemoglobin disorders are among the most common inherited diseases worldwide. Their clinical manifestations range from anemia to more severe forms associated with neurological impairments. These complications can result as secondary consequences of th...
Platinum(II) complexes have been found to be effective against cancer cells. Cisplatin curbs cell replication by interacting with the deoxyribonucleic acid (DNA), reducing cell proliferation and eventually leading to cell death. In order to investiga...
Prostate cancer is the most common illness affecting men worldwide. Although much progress has been made in the study of prostate cancer prevention and treatment, less attention has been paid to the molecular mechanism of the disease. The molecular a...
New heterotrinuclear complexes with the general formula [Cu2Ln(H2L)(HL)(NO3)2]·MeOH (Ln = Ho (1), Er (2), H4L = N,N′-bis(2,3-dihydroxybenzylidene)-1,3-diaminopropane) were synthesized using compartmental Schiff base ligand in conjugation...
Copper is an essential trace element that plays critical roles in enzymatic processes and cellular metabolism. However, excessive exposure to its ions can lead to toxicity through oxidative stress mechanisms. Therefore, the chemical ‘speciation...
In this paper attenuated total reflectance Fourier transform infrared spectroscopy has been employed for the study of the structural composition of aggregates of the oligomeric L-asparaginase II from E.coli formed in the presence of glycerol after th...
Copper complexes with 1,3-disubstituted thiourea derivatives, all containing 3-(trifluoromethyl)phenyl tail and 1-alkyl/halogen-phenyl substituent, were synthesized. The experimental spectroscopic studies and theoretical calculation revealed that two...
The purpose of this study was to investigate the clinical results at five years’ follow-up of a tri-layered nanostructured biomimetic osteochondral scaffold used for focal articular cartilage defects in patients meeting the criteria of early os...
Autophagy is activated by various stresses, including DNA damage, and previous studies of DNA damage-induced autophagy have focused on the response to chemotherapeutic drugs, ionizing radiation, and reactive oxygen species. In this study, we investig...
The hydrothermal reaction of 4,4′-bis(1,2,4-triazol-4-yl) (btr) and benzene-1,3,5-tricarboxylic acid (H3btc) with Cd(OAc)2·2H2O at 125 °C in situ forms 4-amino-1,2,4-triazole (atr) from btr, which crystallizes to a mixed-ligand, poly-anionic chain of...
Since the first report in 1978, the number of individuals conceived by Assisted Reproductive Technologies (ART) has grown incessantly. In parallel, with the recent emergence of possible underlying mechanisms of ART-induced epigenetic changes in the r...
Atrazine (2-chloro-4-ethytlamino-6-isopropylamine-1,3,5-triazine; ATR) is widely used as a broad-spectrum herbicide. Animal studies have demonstrated that ATR exposure can cause cell death in dopaminergic neurons. The molecular mechanisms underlying...
Fusarium graminearum is the predominant causal agent of cereal Fusarium head blight disease (FHB) worldwide. The application of chemical fungicides such as azole antifungals is still the primary method for FHB control. However, to date, our knowledge...
Chitosan or polyvinyl pyrrolidone (PVP) were used in combination with hydroxypropyl methylcellulose (HPMC) and poloxamer 407 (P407) as gelling agents for oral drug delivery. The performance interaction with mucin of chitosan-composed gel (F1) and PVP...
Differential profile of membrane lipids and pigments of a Synechococcus sp. cyanobacterial strain cells exposed to blue, green, red and white light are determined by means of liquid chromatography and mass spectrometry or diode array detection. Raman...
Angiotensin II (Ang II) upregulates transforming growth factor-beta1 (TGF-β1) and endothelin-1 (ET-1) in various types of cells, and all of them act as profibrotic mediators. However, the signal transduction of angiotensin II receptor (ATR) for...
This study aims to compare photoacoustic (FTIR–PAS), diffuse reflectance (DRIFT), and attenuated total reflection (ATR) FTIR modalities in the wide wavenumber range from NIR (7500 cm−1) to FIR (150 cm−1) for the same silicate soil samples under the s...
The interaction of preorganized iron(II) pivalate complexes with aromatic N-donor ligand (pyridine (py) or 2,2′-bipyridine (bpy)) and 1,4-diaminobutane (dab, putrescine) in anhydrous acetonitrile yielded a new 2D coordination polymer [Fe(piv)2(...
FeII-doped zinc ferrite nanocrystals (FeIIxZn1-xFeIII2O4) were prepared via a sol–gel approach in the presence of polyvinyl alcohol as a stabilizer and assessed for their capability to eliminate crystal violet (CV) dye from water-based solution...
Selective killing of cancer cells while sparing healthy ones is the principle of the perfect cancer treatment and the primary aim of many oncologists, molecular biologists, and medicinal chemists. To achieve this goal, it is crucial to understand the...
The absorption modulating activity of two alkylglycerol derivatives (batyl and chimyl alcohol) on skin barrier properties was evaluated. Biophysical tests such as transepidermal water loss (TEWL) and attenuated total reflectance–Fourier transform inf...
In this paper, we describe and verify the structures and biological activity of novel metal complexes derived from 5-carboxy-2-thiouracil. We outline a synthesis method and assess the antimicrobial activity of newly formed Cu(II), Ni(II) and Co(II) c...
In this work, spent coffee grounds, an abundant agro-waste, were transformed into activated carbon, providing a sustainable substrate for immobilizing 1,10-phenanthroline-5-amine chelating agent, to develop a solid-phase extractant for trace metals....
The objective of this work was to study the polymorphic transformation of carbamazepine from Form II to Form III in 1-propanol during seeded isothermal batch crystallization. First, the pure Form II and Form III were obtained and characterized. Then...
Background/Objectives: This is a study of adolescents with idiopathic scoliosis (IS), treated by the Functional Individual Therapy of Scoliosis (FITS) method. The hypothesis was that active parental involvement in the treatment process enhances the o...
The climate impact of aviation is considerably different from that of other transport modes. The turbofan engine’s efficiency can be increased by increasing the Operating Pressure Ratio (OPR), bypass ratio (BPR) and Turbine Inlet Temperature (T...
Background: The study exploited, for the first time, Attenuated Total Reflectance-Fourier Transform-InfraRed (ATR-FTIR) spectroscopy on human dental pulps at different timings of root resorption (RR) to deepen the biological mechanisms occurring in d...
Coal fly ash-derived cenospheres represent a secondary aluminosilicate resource that can be converted into zeolitic materials for metal removal from water. In this study, acid-pretreated and NaOH-activated cenospheres were crystallized by conventiona...
Efficient and selective extractions of precious and critical metal ions such as Au(III) and Pd(II) were investigated using zirconia nanoparticles surface modified with different organic mono- and di-carbamoyl phosphonic acid ligands. The modification...
The aim of the presented research was to investigate the mechanism of sorption of Cu(II) ions on the commercially available Purolite S 940 and Purolite S 950 chelating ion exchangers with the aminophosphonic functional groups. In order to understand...
The recovery of La(III) and Ni(II) ions by a macroporous cation exchanger in sodium form (Lewatit Monoplus SP112) has been studied in batch experiments under varying HNO3 concentrations (0.2–2.0 mol/dm3), La(III) and Ni(II) concentrations (25&n...
Sperm cryopreservation produces a series of physicochemical phenomena that negatively impact the function and structure of spermatozoa, including the mobilization of cholesterol from the plasma membrane. The use of attenuated total reflection–F...
19 June 2019
The aim of this work was to ascertain the effects of Pb(II) and Cr(VI) on bacterial growth, generation of reactive oxygen species (ROS), activities of superoxide dismutase (SOD), and catalase (CAT), as well as the localization of bioaccumulated heavy...
Salinomycin is a polyether ionophorous antibiotic with promising antineoplastic properties. Published studies have revealed that the compound also exerts pronounced antidotal activity against cadmium (Cd) and lead (Pb) intoxications. It has been prov...
The widespread, worldwide utilisation of alkaline batteries requires development of proper recycling methods for used batteries, which are considered both as a secondary source of valuable metals and as a threat to the environment (may contain toxic...
Decellularized membranes (DM) were obtained from bovine amniotic membranes (BAM) using four different decellularization protocols, based on physical, chemical, and mechanical treatment. The new material was used as a biological scaffold for in vitro...
In this study, the Pb(II) adsorption capabilities of the heavy metal tolerant strain of fungus, Aspergillus piperis, were studied. This study involved finding optimal growth conditions using a plating technique, and optimal adsorption conditions usin...
This study is focused on the visualization of latent fingerprints on brass surfaces using the method of electrochemical deposition of a polymer film based on poly(neutral red) (PNR). The experiment included (i) optimization of conditions of electroch...
The present study examines the durability properties of Class 1 (50–75 MPa) high-performance concrete (HPC) blended with rice husk ash (RHA) as a partial replacement of CEM II B-L, 42.5 N. Six HPC mixes were prepared with RHA and used as 5%, 10...
Endocrine disruptors (EDs) are chemical substances capable of affecting endocrine system functioning and interfering with organ morphogenesis and physiological functions. The development and regeneration of bone tissues have a complex hormonal regula...
As survival in breast cancer patients from newer therapies increases, concerns for chemotherapy-induced cardiotoxicity (CIC) have offset some of these benefits, manifesting as a decline in left ventricular ejection fraction (LVEF). Patients receiving...
In this study, the suitability of attenuated total reflection (ATR) mid-infrared (MIR) spectroscopy, combined with principal component analysis (PCA) and partial least squares (PLS) regression, was evaluated as a rapid analytical technique for the cl...
Background: The increased cardiovascular morbidity and mortality observed in chronic kidney disease (CKD) patients can be partly explained by the presence of carbamoylated lipoproteins. Lipid profiles can be determined with infrared spectroscopy. In...
The aim of the present study is to synthesize new metal complexes of 6-methyl-2-thiouracil and 6-propyl-2-thiouracil, elucidate their structures, and investigate their biological properties. All metal complexes were obtained after mixing water soluti...
New research applications involving the use of cellulosic material derived from maize stalk for on-site treatment of leachate were evaluated for specific removal of Cu(II) and Fe(III) from real, highly polluted tailing pond and mine wastewater sample...
This study presents fibers based on methacrylic acid–methyl methacrylate (Eudragit L100) as Cu(II) adsorbents, resulting in antimicrobial complexes. Eudragit L100, an anionic copolymer synthesized by radical polymerization, was electrospun in d...
The measurement of oxygen consumption is an important element in the understanding of an organism’s metabolic state. Oxygen is also a phosphorescence quencher, which allows the evaluation of phosphorescence emitted by oxygen sensors. Two Ru(II)...
Attenuated total reflection–Fourier transform infrared (ATR–FTIR) spectroscopy is a simple, cheap, and fast method to collect chemical compositional information from microalgae. However, (semi)quantitative evaluation of the collected data can be daun...
In this study, membrane fouling caused by paperboard mill treated effluent (PMTE) was investigated based on a dead-end ultrafiltration (UF) pilot-scale study. The membranes employed were commercial hydrophobic UF membranes made of polyethersulfone (P...
Magnesium(II) sulfanyl porphyrazine with peripheral morpholinethoxy substituents was embedded on the surface of titanium(IV) dioxide nanoparticles. The obtained nanocomposites were characterized with the use of particle size and distribution (NTA ana...
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