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Announcements
22 December 2023
Cells | Top Cited Papers in 2022 in the Section “Cell Proliferation and Division”
“Estimating Biomass and Vitality of Microalgae for Monitoring Cultures: A Roadmap for Reliable Measurements”
by Michael Schagerl, Rainer Siedler, Eliška Konopáčová and Sameh Samir Ali
Cells 2022, 11(15), 2455; https://doi.org/10.3390/cells11152455
Available online: https://www.mdpi.com/2073-4409/11/15/2455
“Advances in the Current Understanding of How Low-Dose Radiation Affects the Cell Cycle”
by Md Gulam Musawwir Khan and Yi Wang
Cells 2022, 11(3), 356; https://doi.org/10.3390/cells11030356
Available online: https://www.mdpi.com/2073-4409/11/3/356
“The Effect of Variable Light Source and Light Intensity on the Growth of Three Algal Species”
by Vitali Bialevich, Vilém Zachleder and Kateřina Bišová
Cells 2022, 11(8), 1293; https://doi.org/10.3390/cells11081293
Available online: https://www.mdpi.com/2073-4409/11/8/1293
“A Journey through Time on the Discovery of Cell Cycle Regulation”
by Rustem Uzbekov and Claude Prigent
Cells 2022, 11(4), 704; https://doi.org/10.3390/cells11040704
Available online: https://www.mdpi.com/2073-4409/11/4/704
“Enhanced Photodynamic Therapy: A Review of Combined Energy Sources”
by José A. Rodrigues and José H. Correia
Cells 2022, 11(24), 3995; https://doi.org/10.3390/cells11243995
Available online: https://www.mdpi.com/2073-4409/11/24/3995
“NGLY1 Deficiency, a Congenital Disorder of Deglycosylation: From Disease Gene Function to Pathophysiology”
by Ashutosh Pandey, Joshua M. Adams, Seung Yeop Han and Hamed Jafar-Nejad
Cells 2022, 11(7), 1155; https://doi.org/10.3390/cells11071155
Available online: https://www.mdpi.com/2073-4409/11/7/1155
“Cyclin-Dependent Kinases and CTD Phosphatases in Cell Cycle Transcriptional Control: Conservation across Eukaryotic Kingdoms and Uniqueness to Plants”
by Zhi-Liang Zheng
Cells 2022, 11(2), 279; https://doi.org/10.3390/cells11020279
Available online: https://www.mdpi.com/2073-4409/11/2/279
“Modulation of Cell-Cycle Progression by Hydrogen Peroxide-Mediated Cross-Linking and Degradation of Cell-Adhesive Hydrogels”
by Wildan Mubarok, Kelum Chamara Manoj Lakmal Elvitigala, Masaki Nakahata, Masaru Kojima and Shinji Sakai
Cells 2022, 11(5), 881; https://doi.org/10.3390/cells11050881
Available online: https://www.mdpi.com/2073-4409/11/5/881
“Cell Cycle Regulation by Heat Shock Transcription Factors”
by Yasuko Tokunaga, Ken-Ichiro Otsuyama and Naoki Hayashida
Cells 2022, 11(2), 203; https://doi.org/10.3390/cells11020203
Available online: https://www.mdpi.com/2073-4409/11/2/203
“An Unanticipated Modulation of Cyclin-Dependent Kinase Inhibitors: The Role of Long Non-Coding RNAs”
by Debora Bencivenga, Emanuela Stampone, Angela Vastante, Myassar Barahmeh, Fulvio Della Ragione and Adriana Borriello
Cells 2022, 11(8), 1346; https://doi.org/10.3390/cells11081346
Available online: https://www.mdpi.com/2073-4409/11/8/1346
21 December 2023
Cells | Top Cited Papers in 2022 in the Section “Cellular Aging”
“Interconnections between Inflammageing and Immunosenescence during Ageing”
by Thibault Teissier, Eric Boulanger and Lynne S. Cox
Cells 2022, 11(3), 359; https://doi.org/10.3390/cells11030359
Available online: https://www.mdpi.com/2073-4409/11/3/359
“Aging of the Immune System: Focus on Natural Killer Cells Phenotype and Functions”
by Ashley Brauning, Michael Rae, Gina Zhu, Elena Fulton, Tesfahun Dessale Admasu, Alexandra Stolzing and Amit Sharma
Cells 2022, 11(6), 1017; https://doi.org/10.3390/cells11061017
Available online: https://www.mdpi.com/2073-4409/11/6/1017
“GBA Variants and Parkinson Disease: Mechanisms and Treatments”
by Laura Smith and Anthony H. V. Schapira
Cells 2022, 11(8), 1261; https://doi.org/10.3390/cells11081261
Available online: https://www.mdpi.com/2073-4409/11/8/1261
“Epigenetic Regulation of Cellular Senescence”
by Jack Crouch, Maria Shvedova, Rex Jeya Rajkumar Samdavid Thanapaul, Vladimir Botchkarev and Daniel Roh
Cells 2022, 11(4), 672; https://doi.org/10.3390/cells11040672
Available online: https://www.mdpi.com/2073-4409/11/4/672
“RhoA Signaling in Neurodegenerative Diseases”
by Sissel Ida Schmidt, Morten Blaabjerg, Kristine Freude and Morten Meyer
Cells 2022, 11(9), 1520; https://doi.org/10.3390/cells11091520
Available online: https://www.mdpi.com/2073-4409/11/9/1520
“Overview of Polyamines as Nutrients for Human Healthy Long Life and Effect of Increased Polyamine Intake on DNA Methylation”
by Kuniyasu Soda
Cells 2022, 11(1), 164; https://doi.org/10.3390/cells11010164
Available online: https://www.mdpi.com/2073-4409/11/1/164
“Blood-Based Biomarkers for Alzheimer’s Disease Diagnosis and Progression: An Overview”
by Angelica Varesi, Adelaide Carrara, Vitor Gomes Pires, Valentina Floris, Elisa Pierella, Gabriele Savioli, Sakshi Prasad, Ciro Esposito, Giovanni Ricevuti, Salvatore Chirumbolo et al.
Cells 2022, 11(8), 1367; https://doi.org/10.3390/cells11081367
Available online: https://www.mdpi.com/2073-4409/11/8/1367
“The Senescence Markers p16INK4A, p14ARF/p19ARF and p21 in Organ Development and Homeostasis”
by Kay-Dietrich Wagner and Nicole Wagner
Cells 2022, 11(12), 1966; https://doi.org/10.3390/cells11121966
Available online: https://www.mdpi.com/2073-4409/11/12/1966
“Effects of Air Pollution on Cellular Senescence and Skin Aging”
by Ines Martic, Pidder Jansen-Dürr and Maria Cavinato
Cells 2022, 11(14), 2220; https://doi.org/10.3390/cells11142220
Available online: https://www.mdpi.com/2073-4409/11/14/2220
“Yeast Chronological Lifespan: Longevity Regulatory Genes and Mechanisms”
by Mario G. Mirisola and Valter D. Longo
Cells 2022, 11(10), 1714; https://doi.org/10.3390/cells11101714
Available online: https://www.mdpi.com/2073-4409/11/10/1714
“NADPH and Mitochondrial Quality Control as Targets for a Circadian-Based Fasting and Exercise Therapy for the Treatment of Parkinson’s Disease”
by William M. Curtis, William A. Seeds, Mark P. Mattson and Patrick C. Bradshaw
Cells 2022, 11(15), 2416; https://doi.org/10.3390/cells11152416
Available online: https://www.mdpi.com/2073-4409/11/15/2416
“IGF2: Development, Genetic and Epigenetic Abnormalities”
by Céline Sélénou, Frédéric Brioude, Eloïse Giabicani, Marie-Laure Sobrier and Irène Netchine
Cells 2022, 11(12), 1886; https://doi.org/10.3390/cells11121886
Available online: https://www.mdpi.com/2073-4409/11/12/1886
“Skin-Aging Pigmentation: Who Is the Real Enemy?”
by Jin Cheol Kim, Tae Jun Park and Hee Young Kang
Cells 2022, 11(16), 2541; https://doi.org/10.3390/cells11162541
Available online: https://www.mdpi.com/2073-4409/11/16/2541
“Maintenance of Chronological Aging Features in Culture of Normal Human Dermal Fibroblasts from Old Donors”
by Julie Rorteau, Fabien P. Chevalier, Sébastien Bonnet, Théo Barthélemy, Amandine Lopez-Gaydon, Lisa S. Martin, Nicolas Bechetoille and Jérôme Lamartine
Cells 2022, 11(5), 858; https://doi.org/10.3390/cells11050858
Available online: https://www.mdpi.com/2073-4409/11/5/858
“Pathological Relevance of Post-Translationally Modified Alpha-Synuclein (pSer87, pSer129, nTyr39) in Idiopathic Parkinson’s Disease and Multiple System Atrophy”
by Berkiye Sonustun, Melek Firat Altay, Catherine Strand, Kirsten Ebanks, Geshanthi Hondhamuni, Thomas T. Warner, Hilal A. Lashuel and Rina Bandopadhyay
Cells 2022, 11(5), 906; https://doi.org/10.3390/cells11050906
Available online: https://www.mdpi.com/2073-4409/11/5/906
“Central Auditory Functions of Alzheimer’s Disease and Its Preclinical Stages: A Systematic Review and Meta-Analysis”
by Hadeel Y. Tarawneh, Holly K. Menegola, Andrew Peou, Hanadi Tarawneh and Dona M. P. Jayakody
Cells 2022, 11(6), 1007; https://doi.org/10.3390/cells11061007
Available online: https://www.mdpi.com/2073-4409/11/6/1007
“Cellular Senescence in Aging Lungs and Diseases”
by Arbi Aghali, Maunick Lefin Koloko Ngassie, Christina M. Pabelick and Y. S. Prakash
Cells 2022, 11(11), 1781; https://doi.org/10.3390/cells11111781
Available online: https://www.mdpi.com/2073-4409/11/11/1781
“GLP-1 Receptor Agonists in Neurodegeneration: Neurovascular Unit in the Spotlight”
by Giulia Monti, Diana Gomes Moreira, Mette Richner, Henricus Antonius Maria Mutsaers, Nelson Ferreira and Asad Jan
Cells 2022, 11(13), 2023; https://doi.org/10.3390/cells11132023
Available online: https://www.mdpi.com/2073-4409/11/13/2023
“Epigenetic Mechanisms of Senescence in Plants”
by Matin Miryeganeh
Cells 2022, 11(2), 251; https://doi.org/10.3390/cells11020251
Available online: https://www.mdpi.com/2073-4409/11/2/251
“Metabolic Alterations in a Drosophila Model of Parkinson’s Disease Based on DJ-1 Deficiency”
by Cristina Solana-Manrique, Francisco José Sanz, Isabel Torregrosa, Martina Palomino-Schätzlein, Carolina Hernández-Oliver, Antonio Pineda-Lucena and Nuria Paricio
Cells 2022, 11(3), 331; https://doi.org/10.3390/cells11030331
Available online: https://www.mdpi.com/2073-4409/11/3/331
21 December 2023
Cells | Top Cited Papers in 2022
“Advanced Glycation End-Products (AGEs): Formation, Chemistry, Classification, Receptors, and Diseases Related to AGEs”
by Aleksandra Twarda-Clapa, Aleksandra Twarda-Clapa, Aneta M. Białkowska and Maria Koziołkiewicz
Cells 2022, 11(8), 1312; https://doi.org/10.3390/cells11081312
Available online: https://www.mdpi.com/2073-4409/11/8/1312
“Multifactorial Mechanism of Sarcopenia and Sarcopenic Obesity. Role of Physical Exercise, Microbiota and Myokines”
by Jan Bilski, Piotr Pierzchalski, Marian Szczepanik, Joanna Bonior and Jerzy A. Zoladz
Cells 2022, 11(1), 160; https://doi.org/10.3390/cells11010160
Available online: https://www.mdpi.com/2073-4409/11/1/160
“Innate Immune Cell Death in Neuroinflammation and Alzheimer’s Disease”
by Yetirajam Rajesh and Thirumala-Devi Kanneganti
Cells 2022, 11(12), 1885; https://doi.org/10.3390/cells11121885
Available online: https://www.mdpi.com/2073-4409/11/12/1885
“Protective Effects of Curcumin in Cardiovascular Diseases—Impact on Oxidative Stress and Mitochondria”
by Fiona Frederike Cox, Angelina Misiou, Annika Vierkant, Niloofar Ale-Agha, Maria Grandoch, Judith Haendeler and Joachim Altschmied
Cells 2022, 11(3), 342; https://doi.org/10.3390/cells11030342
Available online: https://www.mdpi.com/2073-4409/11/3/342
“Causes of and Molecular Targets for the Treatment of Intervertebral Disc Degeneration: A Review”
by Takashi Ohnishi, Norimasa Iwasaki and Hideki Sudo
Cells 2022, 11(3), 394; https://doi.org/10.3390/cells11030394
Available online: https://www.mdpi.com/2073-4409/11/3/394
“Into the Tissues: Extracellular Matrix and Its Artificial Substitutes: Cell Signalling Mechanisms“
by Aleksandra Bandzerewicz and Agnieszka Gadomska-Gajadhur
Cells 2022, 11(5), 914; https://doi.org/10.3390/cells11050914
Available online: https://www.mdpi.com/2073-4409/11/5/914
“The Role of the Immune System in the Development of Endometriosis“
by Monika Abramiuk, Ewelina Grywalska, Paulina Małkowska, Olga Sierawska, Rafał Hrynkiewicz and Niedźwiedzka-Rystwej
Cells 2022, 11(13), 2028; https://doi.org/10.3390/cells11132028
Available online: https://www.mdpi.com/2073-4409/11/13/2028
“Stem Cells and Angiogenesis: Implications and Limitations in Enhancing Chronic Diabetic Foot Ulcer Healing“
by Vikrant Rai, Rebecca Moellmer and Devendra K. Agrawal
Cells 2022, 11(15), 2287; https://doi.org/10.3390/cells11152287
Available online: https://www.mdpi.com/2073-4409/11/15/2287
“Cardiovascular Inflammaging: Mechanisms and Translational Aspects“
by Maria Luisa Barcena, Muhammad Aslam, Sofya Pozdniakova, Kristina Norman and Yury Ladilov
Cells 2022, 11(6), 1010; https://doi.org/10.3390/cells11061010
Available online: https://www.mdpi.com/2073-4409/11/6/1010
“One-Carbon Metabolism: Pulling the Strings behind Aging and Neurodegeneration“
by Eirini Lionaki, Christina Ploumi and Nektarios Tavernarakis
Cells 2022, 11(2), 214; https://doi.org/10.3390/cells11020214
Available online: https://www.mdpi.com/2073-4409/11/2/214
“Tendon Immune Regeneration: Insights on the Synergetic Role of Stem and Immune Cells during Tendon Regeneration“
by Valentina Russo, Mohammad El Khatib, Giuseppe Prencipe, Maria Rita Citeroni, Melisa Faydaver, Annunziata Mauro, Paolo Berardinelli, Adrián Cerveró-Varona, Arlette A. Haidar-Montes, Maura Turriani et al.
Cells 2022, 11(3), 434; https://doi.org/10.3390/cells11030434
Available online: https://www.mdpi.com/2073-4409/11/3/434
“Necroptosis and Prostate Cancer: Molecular Mechanisms and Therapeutic Potential“
by Giovanni Luca Beretta and Nadia Zaffaroni
Cells 2022, 11(7), 1221; https://doi.org/10.3390/cells11071221
Available online: https://www.mdpi.com/2073-4409/11/7/1221
“Extracellular Release of Mitochondrial DNA: Triggered by Cigarette Smoke and Detected in COPD“
by Luca Giordano, Alyssa D. Gregory, Mireia Pérez Verdaguer, Sarah A. Ware, Hayley Harvey, Evan DeVallance, Tomasz Brzoska, Prithu Sundd, Yingze Zhang, Frank C. Sciurba et al.
Cells 2022, 11(3), 369; https://doi.org/10.3390/cells11030369
Available online: https://www.mdpi.com/2073-4409/11/3/369
“Glucose Regulates m6A Methylation of RNA in Pancreatic Islets”
by Florine Bornaque, Clément Philippe Delannoy, Emilie Courty, Nabil Rabhi, Charlène Carney, Laure Rolland, Maeva Moreno, Xavier Gromada, Cyril Bourouh, Pauline Petit et al.
Cells 2022, 11(2), 291; https://doi.org/10.3390/cells11020291
Available online: https://www.mdpi.com/2073-4409/11/2/291
“High-Fat Diet-Induced Dysregulation of Immune Cells Correlates with Macrophage Phenotypes and Chronic Inflammation in Adipose Tissue”
by Sonia Kiran, Ahmed Rakib, Sunitha Kodidela, Santosh Kumar and Udai P. Singh
Cells 2022, 11(8), 1327; https://doi.org/10.3390/cells11081327
Available online: https://www.mdpi.com/2073-4409/11/8/1327
“Anticoagulants: A Short History, Their Mechanism of Action, Pharmacology, and Indications”
by Marco Heestermans, Géraldine Poenou, Hind Hamzeh-Cognasse, Fabrice Cognasse and Laurent Bertoletti
Cells 2022, 11(20), 3214; https://doi.org/10.3390/cells11203214
Available online: https://www.mdpi.com/2073-4409/11/20/3214
“Probiotics in the Prevention of the Calcium Oxalate Urolithiasis”
by Paulina Wigner, Michał Bijak and Joanna Saluk-Bijak
Cells 2022, 11(2), 284; https://doi.org/10.3390/cells11020284
Available online: https://www.mdpi.com/2073-4409/11/2/284
“The Future of the COVID-19 Pandemic: How Good (or Bad) Can the SARS-CoV2 Spike Protein Get?”
by Matthew A. Nugent
Cells 2022, 11(5), 855; https://doi.org/10.3390/cells11050855
Available online: https://www.mdpi.com/2073-4409/11/5/855
“Dance of The Golgi: Understanding Golgi Dynamics in Cancer Metastasis”
by Rakhee Bajaj, Amanda N. Warner, Jared F. Fradette and Don L. Gibbons
Cells 2022, 11(9), 1484; https://doi.org/10.3390/cells11091484
Available online: https://www.mdpi.com/2073-4409/11/9/1484
“Endothelial Progenitor Cells as Biomarkers of Cardiovascular Pathologies: A Narrative Review”
by Paul Philipp Heinisch, Corina Bello, Maximilian Y. Emmert, Thierry Carrel, Martina Dreßen, Jürgen Hörer, Bernhard Winkler and Markus M. Luedi
Cells 2022, 11(10), 1678; https://doi.org/10.3390/cells11101678
Available online: https://www.mdpi.com/2073-4409/11/10/1678
“Transient Exposure of Endothelial Cells to Doxorubicin Leads to Long-Lasting Vascular Endothelial Growth Factor Receptor 2 Downregulation”
by Silvia Graziani, Luca Scorrano and Giovanna Pontarin
Cells 2022, 11(2), 210; https://doi.org/10.3390/cells11020210
Available online: https://www.mdpi.com/2073-4409/11/2/210
“Mesenchymal Stromal/Stem Cells and Their Products as a Therapeutic Tool to Advance Lung Transplantation”
by Vitale Miceli and Alessandro Bertani
Cells 2022, 11(5), 826; https://doi.org/10.3390/cells11050826
Available online: https://www.mdpi.com/2073-4409/11/5/826
“Pyroptosis and Its Role in SARS-CoV-2 Infection”
by Zsofia Agnes Bittner, Markus Schrader, Shilpa Elizabeth George and Ralf Amann
Cells 2022, 11(10), 1717; https://doi.org/10.3390/cells11101717
Available online: https://www.mdpi.com/2073-4409/11/10/1717
“The H+ Transporter SLC4A11: Roles in Metabolism, Oxidative Stress and Mitochondrial Uncoupling”
by Joseph A. Bonanno, Raji Shyam, Moonjung Choi and Diego G. Ogando
Cells 2022, 11(2), 197; https://doi.org/10.3390/cells11020197
Available online: https://www.mdpi.com/2073-4409/11/2/197
“Molecular Mechanisms of Exercise and Healthspan”
by Yuntian Guan and Zhen Yan
Cells 2022, 11(5), 872; https://doi.org/10.3390/cells11050872
Available online: https://www.mdpi.com/2073-4409/11/5/872
“Modulating the Ubiquitin–Proteasome System: A Therapeutic Strategy for Autoimmune Diseases”
by Dhananjay Yadav, Ji Yeon Lee, Nidhi Puranik, Pallavi S. Chauhan, Vishal Chavda, Jun-O. Jin and Peter C. W. Lee
Cells 2022, 11(7), 1093; https://doi.org/10.3390/cells11071093
Available online: https://www.mdpi.com/2073-4409/11/7/1093
“Understanding Molecular Mechanisms of Phenotype Switching and Crosstalk with TME to Reveal New Vulnerabilities of Melanoma”
by Ahmad Najem, Laura Soumoy, Malak Sabbah, Mohammad Krayem, Ahmad Awada, Fabrice Journe and Ghanem E. Ghanem
Cells 2022, 11(7), 1157; https://doi.org/10.3390/cells11071157
Available online: https://www.mdpi.com/2073-4409/11/7/1157
“Verteporfin Inhibits the Progression of Spontaneous Osteosarcoma Caused by Trp53 and Rb1 Deficiency in Ctsk-Expressing Cells via Impeding Hippo Pathway”
by Yang Li, Shuting Yang and Shuying Yang
Cells 2022, 11(8), 1361; https://doi.org/10.3390/cells11081361
Available online: https://www.mdpi.com/2073-4409/11/8/1361
“Role of Intestinal Dysbiosis and Nutrition in Rheumatoid Arthritis”
by Malavikalakshmi Attur, Jose U Scher, Steven B. Abramson and Mukundan Attur
Cells 2022, 11(15), 2436; https://doi.org/10.3390/cells11152436
Available online: https://www.mdpi.com/2073-4409/11/15/2436
“Apple Derived Exosomes Improve Collagen Type I Production and Decrease MMPs during Aging of the Skin through Downregulation of the NF-κB Pathway as Mode of Action”
by Martina Trentini, Ilaria Zanolla, Federica Zanotti, Elena Tiengo, Danilo Licastro, Simeone Dal Monego, Luca Lovatti and Barbara Zavan
Cells 2022, 11(24), 3950; https://doi.org/10.3390/cells11243950
Available online: https://www.mdpi.com/2073-4409/11/24/3950
“Regulation of Mitochondrial Hydrogen Peroxide Availability by Protein S-glutathionylation”
by Ryan J. Mailloux, Cathryn Grayson and Olivia Koufos
Cells 2023, 12(1), 107; https://doi.org/10.3390/cells12010107
Available online: https://www.mdpi.com/2073-4409/12/1/107
“Transcriptional Heterogeneity and the Microbiome of Cutaneous T-Cell Lymphoma”
by Philipp Licht and Volker Mailander
Cells 2022, 11(3), 328; https://doi.org/10.3390/cells11030328
Available online: https://www.mdpi.com/2073-4409/11/3/328
“Cytochrome c Oxidase Inhibition by ATP Decreases Mitochondrial ROS Production”
by Rabia Ramzan, Amalia M. Dolga, Susanne Michels, Petra Weber, Carsten Culmsee, Ardawan J. Rastan and Sebastian Vogt
Cells 2022, 11(6), 992; https://doi.org/10.3390/cells11060992
Available online: https://www.mdpi.com/2073-4409/11/6/992
“The Protective Action of Metformin against Pro-Inflammatory Cytokine-Induced Human Islet Cell Damage and the Mechanisms Involved”
by Laura Giusti, Marta Tesi, Federica Ciregia, Lorella Marselli, Lorenzo Zallocco, Mara Suleiman, Carmela De Luca, Silvia Del Guerra, Mariachiara Zuccarini, Marco Trerotola et al.
Cells 2022, 11(15), 2465; https://doi.org/10.3390/cells11152465
Available online: https://www.mdpi.com/2073-4409/11/15/2465
“Neurodegenerative Disease-Associated TDP-43 Fragments Are Extracellularly Secreted with CASA Complex Proteins”
Elena Casarotto, Daisy Sproviero, Eleonora Corridori, Maria Cristina Gagliani, Marta Cozzi, Marta Chierichetti, Riccardo Cristofani, Veronica Ferrari, Mariarita Galbiati, Francesco Mina et al.
Cells 2022, 11(3), 516; https://doi.org/10.3390/cells11030516
Available online: https://www.mdpi.com/2073-4409/11/3/516
“The Cell Membrane of a Novel Rhizobium phaseoli Strain Is the Crucial Target for Aluminium Toxicity and Tolerance”
by Clabe Wekesa, John O. Muoma, Michael Reichelt, George O. Asudi, Alexandra C. U. Furch and Ralf Oelmüller
Cells 2022, 11(5), 873; https://doi.org/10.3390/cells11050873
Available online: https://www.mdpi.com/2073-4409/11/5/873
“Senescence-Associated Cell Transition and Interaction (SACTAI): A Proposed Mechanism for Tissue Aging, Repair, and Degeneration”
by Yajun Liu, Jonah Schwam and Qian Chen
Cells 2022, 11(7), 1089; https://doi.org/10.3390/cells11071089
Available online: https://www.mdpi.com/2073-4409/11/7/1089
“Mesenchymal Stromal Cell-Derived Extracellular Vesicles for Neonatal Lung Disease: Tiny Particles, Major Promise, Rigorous Requirements for Clinical Translation”
by Flore Lesage and Bernard Thébaud
Cells 2022, 11(7), 1176; https://doi.org/10.3390/cells11071176
Available online: https://www.mdpi.com/2073-4409/11/7/1176
“The Cytoskeleton Effectors Rho-Kinase (ROCK) and Mammalian Diaphanous-Related (mDia) Formin Have Dynamic Roles in Tumor Microtube Formation in Invasive Glioblastoma Cells”
by Kathryn N. Becker, Krista M. Pettee, Amanda Sugrue, Kevin A. Reinard, Jason L. Schroeder and Kathryn M. Eisenmann
Cells 2022, 11(9), 1559; https://doi.org/10.3390/cells11091559
Available online: https://www.mdpi.com/2073-4409/11/9/1559
“Reactive Oxygen Species in Regulating Lymphangiogenesis and Lymphatic Function”
by Bhupesh Singla, Ravi Varma Aithabathula, Sonia Kiran, Shweta Kapil, Santosh Kumar and Udai P. Singh
Cells 2022, 11(11), 1750; https://doi.org/10.3390/cells11111750
Available online: https://www.mdpi.com/2073-4409/11/11/1750
“Mitochondrial Damage-Associated Molecular Patterns Content in Extracellular Vesicles Promotes Early Inflammation in Neurodegenerative Disorders”
by Cláudia M. Deus, Henrique Tavares, Margarida Beatriz, Sandra Mota and Carla Lopes
Cells 2022, 11(15), 2364; https://doi.org/10.3390/cells11152364
Available online: https://www.mdpi.com/2073-4409/11/15/2364
“Akkermansia muciniphila Reduces Peritonitis and Improves Intestinal Tissue Wound Healing after a Colonic Transmural Defect by a MyD88-Dependent Mechanism”
by Radu Bachmann, Matthias Van Hul, Pamela Baldin, Daniel Léonard, Nathalie M. Delzenne, Clara Belzer, Janneke P. Ouwerkerk, Dirk Repsilber, Ignacio Rangel and Alex Kartheuser
Cells 2022, 11(17), 2666; https://doi.org/10.3390/cells11172666
Available online: https://www.mdpi.com/2073-4409/11/17/2666
“STAT3 and Its Pathways’ Dysregulation—Underestimated Role in Urological Tumors“
by Maciej Golus, Piotr Bugajski, Joanna Chorbińska, Wojciech Krajewski, Artur Lemiński, Jolanta Saczko, Julita Kulbacka, Tomasz Szydełko and Bartosz Małkiewicz
Cells 2022, 11(19), 3024; https://doi.org/10.3390/cells11193024
Available online: https://www.mdpi.com/2073-4409/11/19/3024
“Bone Marrow Mesenchymal Stromal/Stem Cell-Derived Extracellular Vesicles Promote Corneal Wound Repair by Regulating Inflammation and Angiogenesis”
by Gabriele Saccu, Valeria Menchise, Chiara Gai, Marina Bertolin, Stefano Ferrari, Cristina Giordano, Marta Manco, Walter Dastrù, Emanuela Tolosano and Benedetta Bussolati
Cells 2022, 11(23), 3892; https://doi.org/10.3390/cells11233892
Available online: https://www.mdpi.com/2073-4409/11/23/3892
“Enhancing In Vitro Production of the Tree Fern Cyathea delgadii and Modifying Secondary Metabolite Profiles by LED Lighting”
by Wojciech Tomaszewicz, Monika Cioć, Katarzyna Dos Santos Szewczyk, Małgorzata Grzyb, Wioleta Pietrzak, Bożena Pawłowska and Anna Mikuła
Cells 2022, 11(3), 486; https://doi.org/10.3390/cells11030486
Available online: https://www.mdpi.com/2073-4409/11/3/486
“C53 Interacting with UFM1-Protein Ligase 1 Regulates Microtubule Nucleation in Response to ER Stress”
by Anastasiya Klebanovych, Stanislav Vinopal, Eduarda Dráberová, Vladimíra Sládková, Tetyana Sulimenko, Vadym Sulimenko, Věra Vosecká, Libor Macůrek, Agustin Legido and Pavel Dráber
Cells 2022, 11(3), 555; https://doi.org/10.3390/cells11030555
Available online: https://www.mdpi.com/2073-4409/11/3/555
“Targeting Protein O-GlcNAcylation, a Link between Type 2 Diabetes Mellitus and Inflammatory Disease”
by Israel Olapeju Bolanle and Timothy M. Palmer
Cells 2022, 11(4), 705; https://doi.org/10.3390/cells11040705
Available online: https://www.mdpi.com/2073-4409/11/4/705
“How Cargo Identity Alters the Uptake of Cell-Penetrating Peptide (CPP)/Cargo Complexes: A Study on the Effect of Net Cargo Charge and Length”
By Hannah C. Hymel, Alireza Rahnama, Olivia M. Sanchez, Dong Liu, Ted J. Gauthier and Adam T. Melvin
Cells 2022, 11(7), 1195; https://doi.org/10.3390/cells11071195
Available online: https://www.mdpi.com/2073-4409/11/7/1195
“Human Platelet-Rich Plasma Facilitates Angiogenesis to Restore Impaired Uterine Environments with Asherman’s Syndrome for Embryo Implantation and Following Pregnancy in Mice”
by Min Kyoung Kim, Jung Ah Yoon, Sook Young Yoon, Mira Park, Woo Sik Lee, Sang Woo Lyu and Haengseok Song
Cells 2022, 11(9), 1549; https://doi.org/10.3390/cells11091549
Available online: https://www.mdpi.com/2073-4409/11/9/1549
“Targeting Acid Ceramidase Inhibits Glioblastoma Cell Migration through Decreased AKT Signaling”
by Cyntanna C. Hawkins, Amber B. Jones, Emily R. Gordon, Sarah E. Williford, Yuvika Harsh, Julia K. Ziebro, Catherine J. Landis, Sajina Gc, David K. Crossman and Sara J. Cooper
Cells 2022, 11(12), 1873; https://doi.org/10.3390/cells11121873
Available online: https://www.mdpi.com/2073-4409/11/12/1873
21 December 2023
Cells | Top Cited Papers in 2022 in Section “Cell Nuclei: Function, Transport and Receptors”
“Progesterone Actions and Resistance in Gynecological Disorders”
by James A. MacLean II and Kanako Hayashi
Cells 2022, 11(4), 647, https://doi.org/10.3390/cells11040647
Available online: https://www.mdpi.com/2073-4409/11/4/647
“MicroRNA as a Potential Therapeutic Molecule in Cancer”
by Joanna Szczepanek, Monika Skorupa and Andrzej Tretyn
Cells 2022, 11(6), 1008, https://doi.org/10.3390/cells11061008
Available online: https://www.mdpi.com/2073-4409/11/6/1008
“Membrane Progesterone Receptors (mPRs, PAQRs): Review of Structural and Signaling Characteristics”
by Peter Thomas
Cells 2022, 11(11), 1785, https://doi.org/10.3390/cells11111785
Available online: https://www.mdpi.com/2073-4409/11/11/1785
“The Nuclear Pore Complex: Birth, Life, and Death of a Cellular Behemoth”
by Elisa Dultz, Matthias Wojtynek, Ohad Medalia and Evgeny Onischenko
Cells 2022, 11(9), 1456, https://doi.org/10.3390/cells11091456
Available online: https://www.mdpi.com/2073-4409/11/9/1456
“The Regulatory Functions and the Mechanisms of Long Non-Coding RNAs in Cervical Cancer”
by Qiwei Yang and Ayman Al-Hendy
Cells 2022, 11(7), 1149, https://doi.org/10.3390/cells11071149
Available online: https://www.mdpi.com/2073-4409/11/7/1149
“From Molecular Mechanisms to Therapeutics: Understanding MicroRNA-21 in Cancer”
by Jiho Rhim, Woosun Baek, Yoona Seo and Jong Heon Kim
Cells 2022, 11(18), 2791, https://doi.org/10.3390/cells11182791
Available online: https://www.mdpi.com/2073-4409/11/18/2791
“Constitutive Heterochromatin in Eukaryotic Genomes: A Mine of Transposable Elements”
by René Massimiliano Marsano and Patrizio Dimitri
Cells 2022, 11(5), 761, https://doi.org/10.3390/cells11050761
Available online: https://www.mdpi.com/2073-4409/11/5/761
“Current Methods and Pipelines for Image-Based Quantitation of Nuclear Shape and Nuclear Envelope Abnormalities”
by Anne F. J. Janssen, Sophia Y. Breusegem and Delphine Larrieu
Cells 2022, 11(3), 347, https://doi.org/10.3390/cells11030347
Available online: https://www.mdpi.com/2073-4409/11/3/347
“Generating Membrane Curvature at the Nuclear Pore: A Lipid Point of View”
by Bas W. A. Peeters, Alexandra C. A. Piët and Maarten Fornerod
Cells 2022, 11(3), 469, https://doi.org/10.3390/cells11030469
Available online: https://www.mdpi.com/2073-4409/11/3/469
“SWI/SNF Antagonism of PRC2 Mediates Estrogen-Induced Progesterone Receptor Expression”
by Mike R. Wilson, Jake J. Reske, Julie Koeman, Marie Adams, Niraj R. Joshi, Asgerally T. Fazleabas and Ronald L. Chandler
Cells 2022, 11(6), 1000, https://doi.org/10.3390/cells11061000
Available online: https://www.mdpi.com/2073-4409/11/6/1000
“Progesterone Signaling in Endometrial Epithelial Organoids”
by Sylvia C. Hewitt, San-pin Wu, Tianyuan Wang, Steven L. Young, Thomas E. Spencer and Francesco J. DeMayo
Cells 2022, 11(11), 1760, https://doi.org/10.3390/cells11111760
Available online: https://www.mdpi.com/2073-4409/11/11/1760
“Genotype-Phenotype Correlations in Human Diseases Caused by Mutations of LINC Complex-Associated Genes: A Systematic Review and Meta-Summary”
by Emily C. Storey and Heidi R. Fuller
Cells 2022, 11(24), 4065, https://doi.org/10.3390/cells11244065
Available online: https://www.mdpi.com/2073-4409/11/24/4065
“miRNA-Dependent Regulation of AKT1 Phosphorylation”
by Mallory I. Frederick, Tarana Siddika, Pengcheng Zhang, Nileeka Balasuriya, Matthew A. Turk, Patrick O’Donoghue and Ilka U. Heinemann
Cells 2022, 11(5), 821, https://doi.org/10.3390/cells11050821
Available online: https://www.mdpi.com/2073-4409/11/5/821
“The Chemopreventive Effects of Polyphenols and Coffee, Based upon a DMBA Mouse Model with microRNA and mTOR Gene Expression Biomarkers”
by Richard Molnar, Laszlo Szabo, Andras Tomesz, Arpad Deutsch, Richard Darago, Bence L. Raposa, Nowrasteh Ghodratollah, Timea Varjas, Balazs Nemeth, Zsuzsanna Orsos et al.
Cells 2022, 11(8), 1300, https://doi.org/10.3390/cells11081300
Available online: https://www.mdpi.com/2073-4409/11/8/1300
“Nuclear Lipid Droplet Birth during Replicative Stress”
by Sylvain Kumanski, Romain Forey, Chantal Cazevieille and María Moriel-Carretero
Cells 2022, 11(9), 1390, https://doi.org/10.3390/cells11091390
Available online: https://www.mdpi.com/2073-4409/11/9/1390
“Progesterone Signaling and Mammalian Ovarian Follicle Growth Mediated by Progesterone Receptor Membrane Component Family Members”
by John J. Peluso
Cells 2022, 11(10), 1632, https://doi.org/10.3390/cells11101632
Available online: https://www.mdpi.com/2073-4409/11/10/1632
“MicroRNAs as Potential Tools for Predicting Cancer Patients’ Susceptibility to SARS-CoV-2 Infection and Vaccination Response”
by Tânia R. Dias, Francisca Dias, Ana Luísa Teixeira, Hugo Sousa, Júlio Oliveira and Rui Medeiros
Cells 2022, 11(15), 2279, https://doi.org/10.3390/cells11152279
Available online: https://www.mdpi.com/2073-4409/11/15/2279
“miR-200c-3p, miR-222-5p, and miR-512-3p Constitute a Biomarker Signature of Sorafenib Effectiveness in Advanced Hepatocellular Carcinoma”
by Patricia de la Cruz-Ojeda, Tobias Schmid, Loreto Boix, Manuela Moreno, Víctor Sapena, Juan M. Praena-Fernández, Francisco J. Castell, Juan Manuel Falcón-Pérez, María Reig, Bernhard Brüne et al.
Cells 2022, 11(17), 2673, https://doi.org/10.3390/cells11172673
Available online: https://www.mdpi.com/2073-4409/11/17/2673
“Partial Disassembly of the Nuclear Pore Complex Proteins during Semi-Closed Mitosis in Dictyostelium discoideum”
by Kristina Mitic, Marianne Grafe, Petros Batsios and Irene Meyer
Cells 2022, 11(3), 407, https://doi.org/10.3390/cells11030407
Available online: https://www.mdpi.com/2073-4409/11/3/407
“Altered RBP1 Gene Expression Impacts Epithelial Cell Retinoic Acid, Proliferation, and Microenvironment”
by Jianshi Yu, Mariarita Perri, Jace W. Jones, Keely Pierzchalski, Natalia Ceaicovscaia, Erika Cione and Maureen A. Kane
Cells 2022, 11(5), 792, https://doi.org/10.3390/cells11050792
Available online: https://www.mdpi.com/2073-4409/11/5/792
21 December 2023
Cells | Top Cited Papers in 2022 in the Section “Cellular Metabolism”
“Role of Dietary Supplements and Probiotics in Modulating Microbiota and Bone Health: The Gut-Bone Axis”
by Alessandro de Sire, Roberto de Sire, Claudio Curci, Fabiana Castiglione and Walter Wahli
Cells 2022, 11(4), 743; https://doi.org/10.3390/cells11040743
Available online: https://www.mdpi.com/2073-4409/11/4/743
“Amino Acid Metabolism in Cancer Drug Resistance”
by Hee-Chan Yoo and Jung-Min Han
Cells 2022, 11(1), 140; https://doi.org/10.3390/cells11010140
Available online: https://www.mdpi.com/2073-4409/11/1/140
“Versatile Triad Alliance: Bile Acid, Taurine and Microbiota”
by Kalina Duszka
Cells 2022, 11(15), 2337; https://doi.org/10.3390/cells11152337
Available online: https://www.mdpi.com/2073-4409/11/15/2337
“Targeting Epigenetic Modifiers of Tumor Plasticity and Cancer Stem Cell Behavior”
by Vigneshwari Easwar Kumar, Roshni Nambiar, Cristabelle De Souza, Audrey Nguyen, Jeremy Chien and Kit S. Lam
Cells 2022, 11(9), 1403; https://doi.org/10.3390/cells11091403
Available online: https://www.mdpi.com/2073-4409/11/9/1403
“Role of Mitochondrial Stress Response in Cancer Progression”
by Yu Geon Lee, Do Hong Park and Young Chan Chae
Cells 2022, 11(5), 771; https://doi.org/10.3390/cells11050771
Available online: https://www.mdpi.com/2073-4409/11/5/771
“Tumor Cell Glycolysis—At the Crossroad of Epithelial–Mesenchymal Transition and Autophagy”
by Fabrizio Marcucci and Cristiano Rumio
Cells 2022, 11(6), 1041; https://doi.org/10.3390/cells11061041
Available online: https://www.mdpi.com/2073-4409/11/6/1041
“The Clinical Chameleon of Autoinflammatory Diseases in Children”
by Eugenio Sangiorgi and Donato Rigante
Cells 2022, 11(14), 2231; https://doi.org/10.3390/cells11142231
Available online: https://www.mdpi.com/2073-4409/11/14/2231
“Pregnant Women and Endocrine Disruptors: Role of P2X7 Receptor and Mitochondrial Alterations in Placental Cell Disorders”
by Sophie Fouyet, Elodie Olivier, Pascale Leproux, Mélody Dutot and Patrice Rat
Cells 2022, 11(3), 495; https://doi.org/10.3390/cells11030495
Available online: https://www.mdpi.com/2073-4409/11/3/495
“Targeting the Gut Microbiome to Treat Metabolic Dysfunction-Associated Fatty Liver Disease: Ready for Prime Time?”
by Nicolas Lanthier and Nathalie Delzenne
Cells 2022, 11(17), 2718; https://doi.org/10.3390/cells11172718
Available online: https://www.mdpi.com/2073-4409/11/17/2718
“Obesity: The Fat Tissue Disease Version of Cancer”
by Besma Boubertakh, Cristoforo Silvestri and Vincenzo Di Marzo
Cells 2022, 11(12), 1872; https://doi.org/10.3390/cells11121872
Available online: https://www.mdpi.com/2073-4409/11/12/1872
“Roles of Palmitoleic Acid and Its Positional Isomers, Hypogeic and Sapienic Acids, in Inflammation, Metabolic Diseases and Cancer”
by Miguel A. Bermúdez, Laura Pereira, Cristina Fraile, Laura Valerio, María A. Balboa and Jesús Balsinde
Cells 2022, 11(14), 2146; https://doi.org/10.3390/cells11142146
Available online: https://www.mdpi.com/2073-4409/11/14/2146
“A Multi-Strain Probiotic Formulation Improves Intestinal Barrier Function by the Modulation of Tight and Adherent Junction Proteins”
by Raffaella di Vito, Carmela Conte and Giovanna Traina
Cells 2022, 11(16), 2617; https://doi.org/10.3390/cells11162617
Available online: https://www.mdpi.com/2073-4409/11/16/2617
“Targeting PGM3 as a Novel Therapeutic Strategy in KRAS/LKB1 Co-Mutant Lung Cancer”
by Hyunmin Lee, Feng Cai, Neil Kelekar, Nipun K. Velupally and Jiyeon Kim
Cells 2022, 11(1), 176; https://doi.org/10.3390/cells11010176
Available online: https://www.mdpi.com/2073-4409/11/1/176
“Intestinal Microbiota Remodeling Protects Mice from Western Diet-Induced Brain Inflammation and Cognitive Decline”
by Prasant Kumar Jena, Tahereh Setayesh, Lili Sheng, Jacopo Di Lucente, Lee Way Jin and Yu-Jui Yvonne Wan
Cells 2022, 11(3), 504; https://doi.org/10.3390/cells11030504
Available online: https://www.mdpi.com/2073-4409/11/3/504
“Prevention of L-Dopa-Induced Dyskinesias by MPEP Blockade of Metabotropic Glutamate Receptor 5 Is Associated with Reduced Inflammation in the Brain of Parkinsonian Monkeys”
by Marc Morissette, Mélanie Bourque, Marie-Ève Tremblay and Thérèse Di Paolo
Cells 2022, 11(4), 691; https://doi.org/10.3390/cells11040691
Available online: https://www.mdpi.com/2073-4409/11/4/691
“Obesity-Associated Cancers: Evidence from Studies in Mouse Models”
by Ho Lee
Cells 2022, 11(9), 1472; https://doi.org/10.3390/cells11091472
Available online: https://www.mdpi.com/2073-4409/11/9/1472
“Implications of a Neuronal Receptor Family, Metabotropic Glutamate Receptors, in Cancer Development and Progression”
by Kevinn Eddy, Mohamad Naser Eddin, Anna Fateeva, Stefano Vito Boccadamo Pompili, Raj Shah, Saurav Doshi and Suzie Chen
Cells 2022, 11(18), 2857; https://doi.org/10.3390/cells11182857
Available online: https://www.mdpi.com/2073-4409/11/18/2857
20 December 2023
Cells | Top 10 Cited Papers in 2022 in the Section “Cell Motility and Adhesion”
The 2022 top 10 papers from the Section “Cell Motility and Adhesion”, published in Cells (ISSN: 2073-4409), are as follows:
“Current Understanding of Asthma Pathogenesis and Biomarkers”
by Nazia Habib, Muhammad Asghar Pasha and Dale D. Tang
Cells 2022, 11(17), 2764; https://doi.org/10.3390/cells11172764
Available online: https://www.mdpi.com/2073-4409/11/17/2764
“Breast Cancer Bone Metastasis: A Narrative Review of Emerging Targeted Drug Delivery Systems”
by Huimin Shao and Pegah Varamini
Cells 2022, 11(3), 388; https://doi.org/10.3390/cells11030388
Available online: https://www.mdpi.com/2073-4409/11/3/388
“Control of Synapse Structure and Function by Actin and Its Regulators”
by Juliana E. Gentile, Melissa G. Carrizales and Anthony J. Koleske
Cells 2022, 11(4), 603; https://doi.org/10.3390/cells11040603
Available online: https://www.mdpi.com/2073-4409/11/4/603
“Cell Cycle Regulation by Integrin-Mediated Adhesion”
by Siamak A. Kamranvar, Bhavna Rani and Staffan Johansson
Cells 2022, 11(16), 2521; https://doi.org/10.3390/cells11162521
Available online: https://www.mdpi.com/2073-4409/11/16/2521
“Comparative Analysis of Gene Expression in Fibroblastic Foci in Patients with Idiopathic Pulmonary Fibrosis and Pulmonary Sarcoidosis”
by Jan C. Kamp, Lavinia Neubert, Helge Stark, Jan B. Hinrichs, Caja Boekhoff, Allison D. Seidel, Fabio Ius, Axel Haverich, Jens Gottlieb, Tobias Welte et al.
Cells 2022, 11(4), 664; https://doi.org/10.3390/cells11040664
Available online: https://www.mdpi.com/2073-4409/11/4/664
“Subacromial Bursa: A Neglected Tissue Is Gaining More and More Attention in Clinical and Experimental Research”
by Franka Klatte-Schulz, Kathi Thiele, Markus Scheibel, Georg N. Duda and Britt Wildemann
Cells 2022, 11(4), 663; https://doi.org/10.3390/cells11040663
Available online: https://www.mdpi.com/2073-4409/11/4/663
“Links of Cytoskeletal Integrity with Disease and Aging”
by Yu Jin Kim, Min Jeong Cho, Won Dong Yu, Myung Joo Kim, Sally Yunsun Kim and Jae Ho Lee
Cells 2022, 11(18), 2896; https://doi.org/10.3390/cells11182896
Available online: https://www.mdpi.com/2073-4409/11/18/2896
“CRISPR/Cas9 Mediated Knockout of Cyclooxygenase-2 Gene Inhibits Invasiveness in A2058 Melanoma Cells”
by Cathleen Haase-Kohn, Markus Laube, Cornelius K. Donat, Birgit Belter and Jens Pietzsch
Cells 2022, 11(4), 749; https://doi.org/10.3390/cells11040749
Available online: https://www.mdpi.com/2073-4409/11/4/749
“Sex Steroids Effects on Asthma: A Network Perspective of Immune and Airway Cells”
by Niyati A. Borkar, Colin Kelly Combs and Venkatachalem Sathish
Cells 2022, 11(14), 2238; https://doi.org/10.3390/cells11142238
Available online: https://www.mdpi.com/2073-4409/11/14/2238
“Pathologic Proteolytic Processing of N-Cadherin as a Marker of Human Fibrotic Disease”
by Paul Durham Ferrell, Kristianne Michelle Oristian, Everett Cockrell and Salvatore Vincent Pizzo
Cells 2022, 11(1), 156; https://doi.org/10.3390/cells11010156
Available online: https://www.mdpi.com/2073-4409/11/1/156
20 December 2023
Meet the Editors | Interview with Dr. Alexander E. Kalyuzhny—Editor-in-Chief of Cells

Dr. Alexander E. Kalyuzhny is a research assistant professor and is affiliated with the Department of Neuroscience at the University of Minnesota, USA. We had the pleasure of meeting him at the Neuroscience 2023 conference and had a discussion in which we learned more about his background, views, and interests.
The following is a brief Q&A with Dr. Alexander E. Kalyuzhny:
1. You are an internationally recognized neurologist—could you share your current research focus with us and what is exciting about it?
To be more precise, I am a neuroscientist rather than a neurologist. My major interest remains in the area of opioids, focussing on the cellular mechanisms underlying antinociception. What recently excited me was the discovery of novel nonaddictive analgesics and precision analgesia that can be delivered at the level of the individual patient.
2. What made you decide to lead this journal?
Dr. Shu-Kun Lin invited me to join and lead Cells, and I accepted his invitation because I wanted to help young scientists advance to the forefront of science. I am glad to be part of Cells and to see you develop so much over the years. I am very motivated to support our journal and to make science accessible to everyone.
3. What suggestions do you have for our journal’s development?
I think Cells is on the right track, but we need to expand the network of experienced reviewers covering the entire landscape of cell biology, and, of course, keep sponsoring different scientific meetings and conferences.
4. What made you move from your home country and pursue research in the USA?
I was invited in 1992 by the Department of Pharmacology, University of Minnesota, to work on a project to study the function of opioid receptors. Back then, I thought it was a temporary endeavor, but as an old saying goes, “Nothing is more permanent than a temporary solution”. I am very passionate about my research and happy to have the opportunity to work with outstanding scientists.
19 December 2023
Cells | Top Cited Papers in 2022 in the Section “Autophagy”
“Chaperone-Mediated Autophagy in Neurodegenerative Diseases and Acute Neurological Insults in the Central Nervous System”
by Haruo Kanno, Kyoichi Handa, Taishi Murakami, Toshimi Aizawa and Hiroshi Ozawa
Cells 2022, 11(7), 1205; https://doi.org/10.3390/cells11071205
Available online: https://www.mdpi.com/2073-4409/11/7/1205
“Mitophagy Regulation Following Myocardial Infarction”
by Annie Turkieh, Yara El Masri, Florence Pinet and Emilie Dubois-Deruy
Cells 2022, 11(2), 199; https://doi.org/10.3390/cells11020199
Available online: https://www.mdpi.com/2073-4409/11/2/199
“Autophagy Contributes to Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Tumors”
by Gabriela Reyes-Castellanos, Nadine Abdel Hadi and Alice Carrier
Cells 2022, 11(3), 426; https://doi.org/10.3390/cells11030426
Available online: https://www.mdpi.com/2073-4409/11/3/426
“Modulating Chaperone-Mediated Autophagy and Its Clinical Applications in Cancer”
by Virginie Hubert, Sebastian Weiss, Andrew Jackson Rees and Renate Kain
Cells 2022, 11(16), 2562; https://doi.org/10.3390/cells11162562
Available online: https://www.mdpi.com/2073-4409/11/16/2562
“Cannabinoids Reduce Extracellular Vesicle Release from HIV-1 Infected Myeloid Cells and Inhibit Viral Transcription”
by Catherine DeMarino, Maria Cowen, Pooja Khatkar, Bianca Cotto, Heather Branscome, Yuriy Kim, Sarah Al Sharif, Emmanuel T. Agbottah, Weidong Zhou, Cecilia T. Costiniuk et al.
Cells 2022, 11(4), 723; https://doi.org/10.3390/cells11040723
Available online: https://www.mdpi.com/2073-4409/11/4/723
“Morphology of Phagophore Precursors by Correlative Light-Electron Microscopy”
by Sigurdur Runar Gudmundsson, Katri A. Kallio, Helena Vihinen, Eija Jokitalo, Nicholas Ktistakis and Eeva-Liisa Eskelinen
Cells 2022, 11(19), 3080; https://doi.org/10.3390/cells11193080
Available online: https://www.mdpi.com/2073-4409/11/19/3080
“Autophagy and Lysosomal Functionality in CMT2B Fibroblasts Carrying the RAB7K126R Mutation”
by Roberta Romano, Victoria Stefania Del Fiore, Paola Saveri, Ilaria Elena Palamà, Chiara Pisciotta, Davide Pareyson, Cecilia Bucci and Flora Guerra
Cells 2022, 11(3), 496; https://doi.org/10.3390/cells11030496
Available online: https://www.mdpi.com/2073-4409/11/3/496
“PINK1 Protects against Staurosporine-Induced Apoptosis by Interacting with Beclin1 and Impairing Its Pro-Apoptotic Cleavage”
by Francesco Brunelli, Liliana Torosantucci, Vania Gelmetti, Davide Franzone, Anne Grünewald, Rejko Krüger, Giuseppe Arena and Enza Maria Valente
Cells 2022, 11(4), 678; https://doi.org/10.3390/cells11040678
Available online: https://www.mdpi.com/2073-4409/11/4/678
“Diving into the Evolutionary History of HSC70-Linked Selective Autophagy Pathways: Endosomal Microautophagy and Chaperone-Mediated Autophagy”
by Simon Schnebert, Maxime Goguet, Emilio J. Vélez, Alexandra Depincé, Florian Beaumatin, Amaury Herpin and Iban Seiliez
Cells 2022, 11(12), 1945; https://doi.org/10.3390/cells11121945
Available online: https://www.mdpi.com/2073-4409/11/12/1945
“In Vitro Anticancer Screening and Preliminary Mechanistic Study of A-Ring Substituted Anthraquinone Derivatives”
by Ibrahim Morgan, Ludger A. Wessjohann and Goran N. Kaluđerović
Cells 2022, 11(1), 168; https://doi.org/10.3390/cells11010168
Available online: https://www.mdpi.com/2073-4409/11/1/168
30 November 2023
MDPI Insights: The CEO's Letter #6 - MDPI Spain Summit and ResearchGate
Welcome to the MDPI Insights: The CEO's Letter.
In these monthly letters, I will showcase two key aspects of our work at MDPI: our commitment to empowering researchers and our determination to facilitating open scientific exchange.
Opening Thoughts

MDPI Spain Summit

Stefan Tochev (CEO, MDPI) gives the opening speech at the MDPI Spain Summit.
On Friday 10 November 2023 I was in Barcelona, Spain, to deliver the opening presentation and participate in a panel at MDPI’s Spain Summit, a two-day event, inspired by our salon events in China.
With 16 Editors-in-Chief (EiCs) and 20 Editorial Board Members (EBMs) in attendance, the event, organized by our conference team and Barcelona office, featured presentations on open access (OA), MDPI, and publishing market trends in Spain.
The event provided a great opportunity to engage with stakeholders from various MDPI journals, including Nutrients, Vaccines, Buildings, IJMS, and others. We were able to gather feedback and have open conversations around manuscript quality, the peer-review process, and journal development, as well as accreditation agencies.
The main objective of this Summit was to bring together Editors representing MDPI journals across various disciplines within Spanish universities and research centers, primarily from the Barcelona area. The aim was to facilitate an open and fruitful discussion regarding the development of their journals, the future of OA in Spain, and to provide meaningful interactions and networking opportunities.
Connecting with Editorial Board Members

Stefan Tochev in conversation with Summit participants: "Our EBMs are passionate about the journals they serve."
Interacting with our EBMs in person provides a valuable opportunity to show how important it is to us to connect with them, hear their perspectives on their journals and learn more about their own experience collaborating with MDPI.
From my conversations, it was clear that our EBMs are passionate about the journals they serve. I know the advice they provide may sometimes involve just small tweaks, but these can lead to important improvements. As the saying goes, small hinges swing open big doors.
As at November 2023, MDPI has over 6,300 EBMs affiliated with Spanish institutions, with more than 30 of them serving as EiCs or section EiCs. Furthermore, over 68,000 Spanish scholars have contributed as reviewers in MDPI journals.
Open Access in Spain
In 2023, Spain implemented legislation mandating immediate OA for all publicly funded research, aligning with the EU’s Plan S initiative to expedite the transition to OA. The Spanish government also approved a four-year, €23.8 million annual budget for the first national OA strategy, aiming to make publicly funded research freely accessible upon publication. This strategy aims to strengthen the quality and transparency of research in Spain, and to help promote movement towards a digital, low-carbon economy.
For further details of Spain's OA policy and the history of government mandates, click here.
Spain has already seen a notable decline in subscription-only articles, decreasing by 62% over a 10-year period, while gold OA increased by 42%. Green OA slightly decreased, suggesting a shift towards publishing in gold OA journals rather than traditional subscription-based ones. Here are some statistics from Scopus.
A big thank-you to the various MDPI teams, including our conference team and the Barcelona office, for organizing this very successful event!

MDPI colleagues from various offices gathered to host and support the first MDPI Spain Summit, in Barcelona, Spain.
I think this type of gathering has the potential to become an annual event in various locations. For example, Manchester could be an option, as we have over 30 EiCs and over 3,000 EBMs in the UK, a top market for MDPI that publishes high-quality research.
Impactful Research

769 Editorial Board Members of MDPI Journals Recognized as Highly Cited Researchers in 2023
Congratulations to our 769 Editorial Board Members from 40 countries/territories who have been awarded Highly Cited Researcher status for 2023 by Clarivate. This recognition is based on their outstanding scientific research contributions and significant influence in various fields, as evidenced by Web of Science data.
Click here to view the full list of 769 Editorial Board Members.
Clarivate's Highly Cited ResearchersTM list identifies individuals with exceptional impact in scientific and social science domains over the past decade. Their papers rank in the top 1% of citations in 21 fields analysed in ‘Essential Science Indicators,’ showcasing their substantial influence.
This year, 7,125 Highly Cited Researcher 2023 designations were issued to 6,849 individuals from 67 countries, representing just 1 in 1,000 researchers worldwide.
These researchers demonstrate exceptional influence, representing a small fraction of contributors pushing the boundaries of knowledge, contributing to global well-being, sustainability, and security.
Congratulations to these scholars for their remarkable achievement: we are honoured to have them on board with our journals!
Inside MDPI

Corporate Marketing and Communications Strategy Session

Members of MDPI’s Corporate Marketing & Communications team.
For the past few years, I have led the Corporate Marketing & Communications department in our annual strategy session.
This typically involves 2–3 days of focused sessions covering key topics including budgeting, hiring targets, campaign reviews, and planning for the upcoming year, department strategy, and structure.
We are constantly exploring ways to optimize the Corporate Marketing & Communications department to support MDPI’s primary objectives and better convey the MDPI story while serving the scholarly community.
The strategy session also serves as a team-building activity, during which the team voted on bowling!
Strategy Session
In this strategy session, we looked at how to align our teams in order to better streamline our content with our campaigns, build a dedicated marketing team to strategically support our core MDPI products, expand our communications teams and functionalities to focus on company-critical campaigns and press releases, align our new brand design system with our marketing initiatives, set up a community and engagement team to support various teams with their outreach and communication efforts, and increase our use of data in the evaluation of campaign performance.
To grow in these areas, we will be hiring for various positions, including those of Public Relations Manager, Communications Manager, Internal Communications Manager, Campaign Manager, Marketing Associate, and Editorial Engagement Manager.
I am grateful for the way our Corporate Marketing & Communications department has grown and gelled over the years, and I look forward to supporting the department teams and their ideas for the future.
Coming Together for Science

ResearchGate and MDPI Partner to Boost the Visibility of Open Access Content through Journal Home

Stefan Tochev (CEO, MDPI) and Sören Hofmayer (Co-Founder and Chief Strategy Officer, ResearchGate) meet in Berlin, Germany to take their ongoing discussion further.
When I assumed the role of CEO at MDPI, my primary focus was to initiate the building of essential partnerships and collaborations within our industry. After all, I am a firm believer in achieving our goals by helping others achieve theirs and focusing on co-opetition wherever there is an opportunity. I first touched on the notion of co-opetition in MDPI Insights: The CEO's Letter #3, particularly when discussing collaborations with Elsevier.
In light of this, Sören Hofmayer (Co-Founder and Chief Strategy Officer at ResearchGate) and I connected recently to continue a discussion that had been ongoing for months. I was quickly brought up to speed and felt there was an opportunity for MDPI journals to pilot the Journal Home service that ResearchGate had launched. This would provide a new way for MDPI to engage with authors and readers and amplify the visibility of our journals.
While I receive many offers and opportunities for discussions with vendors, I am a firm believer that timing is everything, and in this case, the time for us is now. Sören and I met in person during my recent visit to Berlin and decided to proceed with piloting ten MDPI journals with the Journal Home service.
The press release below provides further details.
Press Release: Berlin (Germany) and Basel (Switzerland), 15 November 2023
ResearchGate, the professional network for researchers, and MDPI, the largest open access publisher in the world and a pioneer in open access publishing, today announced a partnership that will see ten of MDPI’s open access journals benefit from an enhanced presence on ResearchGate through its innovative Journal Home offering.
This new partnership will expand the reach and visibility of MDPI’s participating flagship journals with ResearchGate’s highly relevant community of more than 25 million researchers globally.
Around 210,000 version-of-record articles from these 10 titles will be readily available on ResearchGate, including the full archive material and all new articles as they are published. These journals also benefit from enhanced brand visibility, with dedicated journal profiles, prominent representation on all associated article pages and all relevant touchpoints across the ResearchGate network – keeping the journals top-of-mind with their reader and author audiences. All articles covered by the new partnership will automatically be added to the authors’ publication records in ResearchGate. This not only reduces MDPI authors’ needs for direct management but also offers them valuable insights into the impact of their work, including data about readership and citations.
Closing Thoughts

November is Men’s Health Awareness Month

Stefan Tochev (CEO, MDPI) listening to music as he writes at a coffee shop in Basel, Switzerland.
November is dedicated to raising awareness of various men’s health issues. I have been fortunate to have positive male role models in my life, and I strive to share my experiences with others.
I used to take part in Movember, growing my moustache throughout November to raise awareness and funds and to help “change the face of men’s health.” With male family and friends impacted by physical and mental health issues, I have recently become more interested in men’s overall well-being.
Men often face stigma involving the perceived need always to be strong and have things figured out. Recently, I’ve had meaningful conversations with male friends and colleagues about issues we rarely discuss, and it was a positive experience.
Various factors impact men’s health and well-being, all too easily leading to risky health behaviours including a lack of health awareness, poor health education, and negative, culturally induced, behaviour patterns in our work and personal lives. I hope we can break down these barriers in our work environment.
Healthy men help build healthy families and a healthy society
Men are less likely than women to seek help with their physical and mental health struggles. This is a reminder to prioritize your overall well-being. I hope that as men, we will continue to open up to one another, becoming vulnerable in order to share what we are going through. By sharing and by supporting each other, we can learn and grow together. You are not alone, and when you fall, you can still get up and stand tall.
From one broski to another, you are loved and appreciated. I hope this mindset carries into December and beyond.
Mindfulness
Our content team recently released a handful of articles on mindfulness, a practice that I believe provides a good opportunity for stress release and self-reflection:
Chief Executive Officer
MDPI AG
21 November 2023
769 Editorial Board Members of MDPI Journals Achieve Highly Cited Researcher Recognition in 2023
We extend our sincere congratulations to the 769 Editorial Board Members of our journals – from 40 different countries/territories – who have been recognized as Highly Cited Researchers for the year 2023 by Clarivate. They are being recognized for their high-quality scientific research achievements and outstanding contributions to their professional fields, as indicated by Web of Science data.
Clarivate's annual list of Highly Cited ResearchersTM identifies the most highly cited scientists for the past decade who stand out for their significant and broad influence in various scientific and social science domains. Their impactful papers are among the top 1 per cent in the citation distribution of one or more of 21 fields analyzed in the "Essential Science Indicators", distinguishing them as hugely influential among their peers.
This year, 7,125 Highly Cited Researcher 2023 designations were issued to 6,849 individuals from 67 countries, representing just 1 in 1,000 researchers worldwide.
This means that these researchers have demonstrated an incredible level of significant and broad influence in their chosen field or fields over the last decade. They represent a small fraction of the researcher population whose contributions disproportionately push the boundaries of knowledge, enhancing global well-being, sustainability, and security.
Congratulations to the scholars for their noteworthy achievement – we are honored to have them on board with our journals!
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Abate, Antonio |
Jaiswal, Amit K. |
Shen, Zexiang |