Next Article in Journal
Explainable Artificial Intelligence Helps in Understanding the Effect of Fibronectin on Survival of Sepsis
Previous Article in Journal
A Comprehensive Transcriptomic Analysis of Arsenic-Induced Bladder Carcinogenesis
 
 
Review

Role of Intestinal Dysbiosis and Nutrition in Rheumatoid Arthritis

1
Drexel University College of Medicine, Drexel University, Philadelphia, PA 19129, USA
2
Division of Rheumatology, Department of Medicine, NYU Grossman School of Medicine, NYU Langone Health, New York, NY 10003, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Richard O. Williams
Cells 2022, 11(15), 2436; https://doi.org/10.3390/cells11152436
Received: 13 June 2022 / Revised: 2 August 2022 / Accepted: 4 August 2022 / Published: 5 August 2022
Rheumatoid arthritis is a chronic systemic immune-mediated disease caused by genetic and environmental factors. It is often characterized by the generation of autoantibodies that lead to synovial inflammation and eventual multi-joint destruction. A growing number of studies have shown significant differences in the gut microbiota composition of rheumatoid arthritis (RA) patients compared to healthy controls. Environmental factors, and changes in diet and nutrition are thought to play a role in developing this dysbiosis. This review aims to summarize the current knowledge of intestinal dysbiosis, the role of nutritional factors, and its implications in the pathogenesis of rheumatoid arthritis and autoimmunity. The future direction focuses on developing microbiome manipulation therapeutics for RA disease management. View Full-Text
Keywords: arthritis; microbiome; dysbiosis; nutrition arthritis; microbiome; dysbiosis; nutrition
Show Figures

Figure 1

MDPI and ACS Style

Attur, M.; Scher, J.U.; Abramson, S.B.; Attur, M. Role of Intestinal Dysbiosis and Nutrition in Rheumatoid Arthritis. Cells 2022, 11, 2436. https://doi.org/10.3390/cells11152436

AMA Style

Attur M, Scher JU, Abramson SB, Attur M. Role of Intestinal Dysbiosis and Nutrition in Rheumatoid Arthritis. Cells. 2022; 11(15):2436. https://doi.org/10.3390/cells11152436

Chicago/Turabian Style

Attur, Malavikalakshmi, Jose U Scher, Steven B. Abramson, and Mukundan Attur. 2022. "Role of Intestinal Dysbiosis and Nutrition in Rheumatoid Arthritis" Cells 11, no. 15: 2436. https://doi.org/10.3390/cells11152436

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop