We present a novel class of reduced-order regenerator models that is based on Endoreversible Thermodynamics. The models rest upon the idea of an internally reversible (perfect) regenerator, even though they are not limited to the reversible descripti...
Efforts to heal damaged pulp tissue through tissue engineering have produced positive results in pilot trials. However, the differentiation between real regeneration and mere repair is not possible through clinical measures. Therefore, preclinical st...
Heavy petroleum industries, including the Fluid Catalytic Cracking (FCC) unit, are among some of the biggest contributors to global greenhouse gas (GHG) emissions. The FCC unit’s regenerator is where these emissions originate mostly, meaning th...
In the last years, the zebrafish model has become a primary model system for vertebrate tissue regeneration, particularly for neurodegeneration and metabolic disease. Zebrafish (Danio rerio) are small freshwater teleosts valued for disease modelling,...
Dynamic landscape simulation of the forest requires an initial regeneration stock specific to the characteristics of each simulated stand. Forest inventories, however, are sparse with regard to regeneration. Moreover, statistical regeneration models...
Thermal energy storage is essential to compensate for energy peaks and troughs of renewable energy sources. However, to implement this storage in new or existing industries, robust and accurate component models are required. This work examines the de...
Accurate prediction of remaining useful life (RUL) is crucial to the safety and reliability of the lithium-ion battery management system (BMS). However, the performance of a lithium-ion battery deteriorates nonlinearly and is heavily affected by capa...
Forests are one of the most important natural resources for humans, and understanding the regeneration probability of undergrowth in forests is very important for future forest spatial structure and forest management. In addition, the regeneration of...
The adult mammalian heart lacks the ability to sufficiently regenerate itself, leading to the progressive deterioration of function and heart failure after ischemic injuries such as myocardial infarction. Thus far, cell-based therapies have delivered...
Public participation is increasingly becoming a necessary content in community regeneration in China, though there is a lack of evaluation of the public participation process. This study explores a method for evaluating the public participation proce...
This study presents a novel approach to analyzing forest regeneration dynamics by integrating a Markov chain model with Multivariate Time Series (MTY) decomposition. The probabilistic tracking of age-class transitions was combined with the decomposit...
In the European Green Deal and Renovation Wave framework, cities should be more self-sufficient and sustainable, promoting investment in the regeneration and maintenance of the built and natural heritage. The New European Bauhaus reinforces this visi...
The osteochondral interface (OCI) is a structurally and functionally complex tissue whose degeneration or injury often results in poor healing and joint dysfunction due to its avascular and hypocellular nature. Conventional surgical treatments remain...
Urban regeneration can be defined as a multi-functional, specifical zoning application for the improvement and sustainability of an urban area with its physical, environmental, social and economic conditions. The question of where the urban regenerat...
Optimizing in vitro shoot regeneration conditions in wheat is one of the important steps in successful micropropagation and gene transformation. Various factors such as genotypes, explants, and phytohormones affect in vitro regeneration of wheat, hin...
Skeletal muscle injuries that occur from traumatic incidents, such as those caused by car accidents or surgical resections, or from injuries sustained on the battlefield, result in the loss of functionality of the injured muscle. To understand skelet...
This study intends to provide insights into various aspects related to the reaction kinetics of the VOx catalyzed propane dehydrogenation including main and side reactions and, in particular, catalyst deactivation and regeneration, which can be hardl...
The spatial structure of trees is a template for forest dynamics and the outcome of a variety of processes in ecosystems. Identifying the contribution and magnitude of the different drivers is an age-old task in plant ecology. Recently, the modelling...
The fundamental disputes in urban heritage regeneration stem from variations in power dynamics and inherent value systems among stakeholders. Addressing conflicts and power differentials involving governmental bodies, market forces, community residen...
Guided bone regeneration (GBR) plays a key role in alveolar ridge augmentation and implant therapy, but the biological mechanisms governing its outcomes are not fully understood. Preclinical animal models provide critical insights that cannot be obta...
Pneumonia is a cause of high morbidity and mortality in humans. Animal models are indispensable to investigate the complex cellular interactions during lung injury and repair in vivo. The time sequence of lesion development and regeneration is descri...
Three-dimensional (3D) bioprinting provides new options for airway reconstruction by enabling the fabrication of customizable, biodegradable scaffolds designed to support in situ tissue regeneration. Building on our established large-animal platform,...
Open spaces for collective use in the built heritage of cities are the places to promote and sustain social, cultural, and economic changes. The transformation of the built environment raises awareness of following the policies and tools for the impl...
Amid growing demands for urban regeneration, metro station areas (MSAs) have emerged as critical spatial units for assessing renewal potential. However, their highly heterogeneous functional and spatial attributes pose challenges to precise classific...
In the context of the European Green Deal and the New European Bauhaus, circularity and sustainability have emerged as central paradigms for rethinking development models in both urban and rural areas. While most literature focuses on cities, rural v...
Reconstruction of bone due to surgical removal or disease-related bony defects is a clinical challenge. It is known that the immune system exerts positive immunomodulatory effects on tissue repair and regeneration. In this study, we evaluated the in...
This paper focuses on the development of an integrated system that can rapidly and accurately extract the geometrical dimensions of a physical object assisted by a robotic hand and generate a 3D model of an object in a popular commercial Computer-Aid...
Despite advances in microsurgery, full functional recovery of severe peripheral nerve injuries is not commonly attained. The sheep appears as a good preclinical model since it presents nerves with similar characteristics to humans. In this study, we...
Urban regeneration has increasingly become a global strategy for promoting sustainable urban development, with the renewal of deteriorating residential communities serving as a key dimension of this process. Within the framework of a people-centered...
Degenerated intervertebral discs (IVDs) were treated with autologous adipose-derived stem cells (ASC) loaded into an injectable collagen scaffold in a sheep model to investigate the implant’s therapeutic potential regarding the progression of degener...
Alveolar cleft is a common congenital deformity that requires surgical intervention, notably using autologous bone grafts in young children. Bone substitutes, in combination with mesenchymal stem cells (MSCs), have shown promise in the repair of thes...
Nature-based solutions (NBSs) are central to urban climate-neutrality strategies, but their implementation still lags behind policy ambition. One reason is that most NBS benefits are public goods and rarely generate direct revenue, so we know far les...
Resorbable polyglycolic acid (PGA) chondrocyte grafts are clinically established for human articular cartilage defects. Long-term implant performance was addressed in a standardized in vitro model. PGA implants (+/− bovine chondrocytes) were placed i...
The demand of bone graft materials has been increasing. Among various origins of bone graft materials, natural coral composed of up to 99% calcium carbonate was chosen and converted into hydroxyapatite (HA); silicon was then substituted into the HA....
Despite the literature providing compelling evidence for the medical efficacy of photobiomodulation (PBM) therapy, its consistency in terms of accuracy and standardization needs improving. Identification of new technology and reliable and ethical bio...
The development of induced pluripotent stem cells has brought unlimited possibilities to the field of regenerative medicine. This could be ideal for treating osteoarthritis and other skeletal diseases, because the current procedures tend to be short-...
The rat calvarial defect model supports the preclinical evaluation of bone-regenerative approaches relevant to craniofacial reconstruction, including recombinant human bone morphogenetic protein-2 (rhBMP-2) and bone substitutes. However, its invasive...
Background: Bisphosphonates are widely employed drugs for the treatment of pathologies with high bone resorption, such as osteoporosis, and display a great affinity for calcium ions and apatitic substrates. Here, we aimed to investigate the potential...
Historic urban landscapes are at continuous risk of loss due to urban modernization and the demolition of built heritage. Scan-based documentation methods such as laser scanning and photogrammetry become inapplicable, leaving demolished sites undocum...
A heat-integrated packed-bed membrane reactor is studied based on detailed, transient 2D models for coupling oxidative and thermal propane dehydrogenation in one apparatus. The reactor is structured in two telescoped reaction zones to figure out the...
Pedestrian priority is an important requirement for city centre regeneration. The quantitative analysis of the separation degree of pedestrians and vehicles is a key technique to measure the walkability of city centre regeneration. This paper propose...
Water treatment systems based on sodium–cation exchange are widely used at thermal power plants. However, their operation is associated with high consumption of water and sodium chloride during regeneration and the generation of highly minerali...
In this paper, a novel solar solid dehumidification/regeneration bed has been proposed, and its three regeneration methods, i.e., simulated solar radiation regeneration, microwave regeneration, and combined regeneration of the microwave and simulated...
Urban regeneration is an important means for building sustainable cities and implementing China’s high-quality development strategy. In this paper, a sustainable regeneration PSR (Pressure-State-Response) model was established, and a state-laye...
Currently, economic development has become a dominant factor in the promotion of urban regeneration in China. This means that decision makers often overlook the impacts on the natural environment when planning urban regeneration within a region. To p...
The purpose of the study is to show that two simple models that take into account only the irreversibility due to temperature difference in the heat exchangers and imperfect regeneration are able to indicate refrigerating machine behavior. In the pre...
Neurons are structurally unique and have dendrites and axons that are vulnerable to injury. Some neurons in the peripheral nervous system (PNS) can regenerate their axons after injuries. However, most neurons in the central nervous system (CNS) fail...
Digital twin technologies integrate data, models, and physical entities. The paper explores technologies applied in the Urban Digital Twin (UDT) to support Urban regeneration (UR), with a case study of the small historic town of Draguć in Istria...
For the purpose of designing a reasonable control strategy for DOC-assisted DPF regeneration, a mathematical model that describes the thermal phenomenon both in a diesel oxidation catalyst (DOC) and diesel particulate filter (DPF) during regeneration...
Persistence of native forests is a global concern. We aimed at unveiling the main factors affecting tree recruitment in Portuguese native forests, modelling sapling data collected during the 5th Portuguese Forest Inventory, for five main Quercus taxa...
of 101