Special Issue "Pluripotent Stem Cells for Regenerative Medicine"
Deadline for manuscript submissions: 31 December 2021.
Human pluripotent stem cells are slowly but steadily transitioning from bench to bedside, with the first clinical trials showing promising results. Nevertheless, the spectrum of potentially treatable conditions is still limited, and issues such as genome instability and suboptimal differentiation are significant hurdles to the safe transition of these cells to the clinic.
This Special Issue welcomes manuscripts providing insight on aspects relevant to the use of hPSC in regenerative medicine. We are interested in a wide range of work, including differentiation to novel cell types or improvement on existing cell types, and their preclinical testing. Work on biomaterials and scaffolding, with an eye for tissue engineering are also key for advanced hPSC-based therapy. Finally, work on safety, such as addressing the tumorigenic potential of hPSC-derived products, and scalability aspects, such as cell culture, are essential for the successful clinical application of these cells.
Prof. Dr. Claudia Spits
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- regenerative medicine
- clinical testing
- tissue engineering
- genome integrity
- cell culture
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Comparison of differentiation pattern and Wnt/Shh signalling in pluripotent stem cells cultured under different conditions
Authors: Barbara Świerczek-Lasek; Damian Dudka; Damian Bauer; Tomasz Czajkowski; Katarzyna Ilach; Wladyslawa Streminska; Agata Kominek; Katarzyna Piwocka; Maria A. Ciemerych; Karolina Archacka
Affiliation: Faculty of Biology, University of Warsaw; Nencki Insititute of Experimental Biology.
Title: PAX7 impacts at the cell cycle regulation of differentiating mouse pluripotent stem cells.
Authors: Anita Florkowska; Iwona Grabowska; Maria A. Ciemerych; et al.
Affiliation: Faculty of Biology, University of Warsaw
Title: Cell Reprogramming for the Treatment of Huntington’s Disease
Authors: Dr. Ruth Monk and Prof. Bronwen Connor
Affiliation: Department of Pharmacology, Centre for Brain Research, School of Medical Sciences, Faculty of Medical and Health Science, University of Auckland, New Zealand
Title: CRISPR-Cas9 mediated KO of MHCI and MHCII KO in porcine iPSC to generate non-immunogenic stem cells
Authors: Henriette R. Frederiksen; Ditte Pawlowski; Ulrik Døhn; Jan Secher; Pernille Tveden-Nyborg; Kristine Freude
Affiliation: Department for Veterinary and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen, 1870 Frederiksberg, Denmark