This paper, based mainly on astronauts’ first-person writings, historical documents, and my own ethnographic interviews with nine astronauts conducted between 2004 and 2020, explores how encountering the earth and other celestial objects in way...
This overview review aimed to describe the evolution of the characteristics of the research on caffeine effects on strength. A total of 189 experimental studies with 3459 participants were included. The median sample size was 15 participants, with an...
Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) is a neuropeptide with widespread distribution throughout the central and peripheral nervous system as well as in many other peripheral organs. It plays cytoprotective effects mediated mainly...
Frailty refers to the lack of resilience and a reduction in a person’s ability to recover following a health problem, and it is increasingly becoming a challenging aspect of ageing populations. Many older adults are exposed to polypharmacy; i.e...
Grain refinement is of importance for metallic materials since it provides multiple benefits, such as improved castability, reduced casting defects and improved mechanical properties. From extensive research carried out in the past decades, it has be...
A large body of research in the field of psychology currently points to a variety of therapeutic outcomes derived from psychedelically occasioned mystical experience. Moreover, additional research suggests that such benefits to mental and emotional w...
As a new kind of artificial material developed in recent decades, metamaterials exhibit novel performance and the promising application potentials in the field of practical engineering compared with the natural materials. Acoustic metamaterials and p...
Prostanoids are bioactive lipid mediators and take part in many physiological and pathophysiological processes in practically every organ, tissue and cell, including the vascular, renal, gastrointestinal and reproductive systems. In this review, we f...
Metformin is the first-line antidiabetic drug that is widely used in the treatment of type 2 diabetes mellitus (T2DM). Even though the various therapeutic potential of metformin treatment has been reported, as well as the improvement of insulin sensi...
Thanks to its excellent intrinsic properties, diamond is promising for applications of high-power electronic devices, ultraviolet detectors, biosensors, high-temperature tolerant gas sensors, etc. Here, an overview of high-k oxides on hydrogenated-di...
Chronic diseases, including cardiovascular and neurodegenerative diseases and cancer, are significant global health challenges. Oxidative stress, characterized by an imbalance between reactive oxygen species (ROS) production and antioxidant defenses,...
Preimplantation genetic testing for structural rearrangements (PGT-SR) was one of the first applications of PGT, with initial cases being worked up in the Delhanty lab. It is the least well-known of the various forms of PGT but nonetheless provides e...
Nowadays, there has been considerable attention paid toward the recovery of waste plant matrices as possible sources of functional compounds with healthy properties. In this regard, we focus our attention on Salicornia, a halophyte plant that grows a...
This review focuses on the potential health risks of artificial food additives, especially their effects on lung health. Preservatives, synthetic colorants, and flavor enhancers, which are commonly used in processed foods, play roles in worsening res...
One of the major challenges in catalysis is developing catalysts that demonstrate superior catalytic activity, selectivity, and durability [...]
Aging is a complex process that involves many physiological mechanisms that gradually impair normal cellular and tissue function and make us more susceptible to diseases and death. It is influenced by intrinsic factors like cellular function and extr...
The genus Streptomyces is one of the largest producers of secondary metabolites with bioactive properties of interest. However, many of the genes involved in synthesizing these compounds are silenced under laboratory conditions. One of the strategies...
There has been a great interest in evaluating the potential of severe plastic deformation (SPD) to improve the performance of magnesium for biological applications. However, different properties and trends, including some contradictions, have been re...
To prevent short-circuits between the upper and lower switches of power converters from over-current protection, the dead time is mandatory in the switching gating signal for voltage source converters. However, this results in many negative effects o...
In high-speed steel, carbides are essential phase constituents, which have a direct impact on engineering performance and qualities of high-speed steel. The formation, morphology, and distribution of carbides are dictated by alloying elements. In thi...
Flooding is a prevalent and growing problem involving significant economic losses worldwide. Traditional flood mitigation measures are based on the use of levees, dams, dredging, and river channelization, which can distort the perception of risk, lea...
Histo-blood group antigens, which are present on gut epithelial surfaces, function as receptors or attachment factors and mediate susceptibility to rotavirus infection. The major determinant for susceptibility is a functional FUT2 enzyme which mediat...
Current COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has put a spotlight on the spread of infectious diseases brought on by pathogenic airborne bacteria and viruses. In parallel with a relentless search...
This study examined how users acquire spatial knowledge in an onscreen three-dimensional virtual environment when using overview maps. This experiment adopted a three (the size of overview maps) x two (the transparency of overview maps) between-subje...
Hydrogen-based Power Systems (H2PSs) are gaining accelerating momentum globally to reduce energy costs and dependency on fossil fuels. A H2PS typically comprises three main parts: hydrogen production, storage, and power generation, called packages. A...
The aim of this review was to give an overview of the outcomes of the use of different regenerative materials to treat molars with class II furcation defects in patients with periodontitis in comparison with open flap debridement (OFD). A search of f...
Present-day lifestyles associated with high calorie-fat intake and accumulation, as well as energy imbalance, have led to the development of obesity and its comorbidities, which have emerged as some of the major health issues globally. To combat the...
Excellent mechanical properties and chemical stability make carbon nanotubes (CNTs) some of the most promising nanomaterials that can be used in cementitious composites to improve their performance. However, the difficulty of CNTs’ dispersion w...
Prophylactic vaccines against human papillomavirus (HPV) have proven efficacy in those who have not been infected by the virus. However, they do not benefit patients with established tumors. Therefore, the development of therapeutic options for HPV-r...
Multiple factors are involved in the development of cancers and their effects on survival rate. Many are related to chemo-resistance of tumor cells. Thus, treatment with a single therapeutic agent is often inadequate for successful cancer therapy. Id...
Carbon fiber-reinforced polymer (CFRP) composites are used in a variety of applications such as aircraft, automobiles, body armors, and the sports sector owing to their ultra-strong and lightweight characteristics. However, the incorporation of an un...
6 May 2020
Neonicotinoid insecticides are used worldwide and have been demonstrated as toxic to beneficial insects such as honeybees. Their effectiveness is predominantly attributed to their high affinity for insect neuronal nicotinic acetylcholine receptors (n...
Nanostructured semiconducting metal oxides (SMOs) are among the most popular sensing materials for integration into resistive-type gas sensors owing to their low costs and high sensing performances. SMOs can be decorated or doped with noble metals to...
N-acetylcysteine (NAC), which is an acetylated cysteine compound, has aroused scientific interest for decades due to its important medical applications. It also represents a nutritional supplement in the human diet. NAC is a glutathione precursor and...
Background: As the COVID-19 pandemic reached its peak, it became unavoidable that patients with other risk factors for severe pulmonary impairment (such as neuromuscular illnesses) would become afflicted. While the subject of myasthenic crisis second...
The genotoxicity of radiation on germ cells may be passed on to the next generation, thus its elucidation is not only a scientific issue but also an ethical, legal, and social issue in modern society. In this article, we briefly overview the effects...
One of the prime objectives of this review is to understand the role of design parameters on the mechanical properties (Compressive and split tensile strength) of Self-Compacting Concrete (SCC) with recycled aggregates (Recycled Coarse Aggregates (RC...
Polyamines, spermidine and spermine, are synthesized in every living cell and are therefore contained in foods, especially in those that are thought to contribute to health and longevity. They have many physiological activities similar to those of an...
5 March 2022
Chronic non-communicable diseases are the major cause of death globally. Whole grains are recommended in dietary guidelines worldwide due to increasing evidence that their consumption can improve health beyond just providing energy and nutrients. Epi...
In metal hydride beds (MHBs), reaction heat transfer often limits the dynamic performance. Heat transfer within the MHB usually involves solid and gas phases. To account for both, an effective thermal conductivity (ETC) is defined. Measuring and pred...
Cocaine is one of the most widely used drugs that, due to its molecular properties, causes various behavioral alterations, including sexual behavior. In vivo and in vitro studies conducted mainly in mammals have shown various disorders of sexual acti...
Caffeine is a naturally occurring alkaloid found in various plants. It acts as a stimulant, antioxidant, anti-inflammatory, and even an aid in pain management, and is found in several over-the-counter medications. This naturally derived bioactive com...
Optimisation of plaque control is essential for the success of non-surgical and surgical periodontal therapy. This cannot be achieved with brushing alone; hence, there is a need for adjunctive interdental cleaning aids. The aim of this paper is to pr...
Concerns and uncertainties persist about potential environmental and health effects associated with exposure to emissions from widely adopted waste management facilities: despite a limited amount of evidence having been found for some exposure-effect...
In this study, polyethylene terephthalate (PET) was substituted for 10%, 20%, and 30% of the sand volume in concrete. Compressive, splitting tensile, and flexural strength tests were applied to the concrete samples and stress–strain graphs were...
In the last decade there has been tremendous effort in offering better therapeutic management strategies to patients with hematologic malignancies. These efforts have ranged from biological to clinical approaches and resulted in the rapid development...
Many patients with cancer make use of complementary medicine alongside conventional medicine, but clinicians in oncology often lack the knowledge to adequately advise patients on the evidence base for complementary therapies. This study aims to provi...
Wound healing implicates several biological and molecular events, such as coagulation, inflammation, migration-proliferation, and remodeling. Here, we provide an overview of the effects of malnutrition and specific nutrients on this process, focusing...
The widespread use of drugs is a global problem which affects not only humans but also the environment around them, as research is showing the presence of these substances in different environmental matrices, like air, water, and soil. Above all, due...
Due to the progressive ageing of the human population, the number of cancer cases is increasing. For this reason, there is an urgent need for new treatments that can prolong the lives of cancer patients or ensure them a good quality of life. Although...
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