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54,999 Results Found

  • Review
  • Open Access
181 Citations
22,498 Views
52 Pages

Fiber-Optic Chemical Sensors and Fiber-Optic Bio-Sensors

  • Marie Pospíšilová,
  • Gabriela Kuncová and
  • Josef Trögl

30 September 2015

This review summarizes principles and current stage of development of fiber-optic chemical sensors (FOCS) and biosensors (FOBS). Fiber optic sensor (FOS) systems use the ability of optical fibers (OF) to guide the light in the spectral range from ult...

  • Review
  • Open Access
16 Citations
4,679 Views
21 Pages

Organic Electro-Optic Materials with High Electro-Optic Coefficients and Strong Stability

  • Shuhui Feng,
  • Shuangke Wu,
  • Weijun Zhang,
  • Fenggang Liu and
  • Jiahai Wang

The preparation of high-performance electro-optical materials is one of the key factors determining the application of optoelectronic communication technology such as 5G communication, radar detection, terahertz, and electro-optic modulators. Organic...

  • Article
  • Open Access
4 Citations
1,827 Views
8 Pages

26 October 2022

Traumatic optic neuropathy (TON) is damage to the optic nerve that is caused by external violence to the optic nerve during cranial and facial trauma. This kind of injury may result in impaired vision, has a high risk of blindness, and significantly...

  • Review
  • Open Access
17 Citations
5,068 Views
19 Pages

Erythropoietin in Optic Neuropathies: Current Future Strategies for Optic Nerve Protection and Repair

  • Yi-Fen Lai,
  • Ting-Yi Lin,
  • Pin-Kuan Ho,
  • Yi-Hao Chen,
  • Yu-Chuan Huang and
  • Da-Wen Lu

Erythropoietin (EPO) is known as a hormone for erythropoiesis in response to anemia and hypoxia. However, the effect of EPO is not only limited to hematopoietic tissue. Several studies have highlighted the neuroprotective function of EPO in extra-hem...

  • Review
  • Open Access
7 Citations
4,791 Views
38 Pages

13 June 2025

Tunable photonic devices are increasingly pivotal in modern optical systems, enabling the dynamic control over light propagation, modulation, and filtering. This review systematically explores two prominent classes of materials, thermo-optic and elec...

  • Article
  • Open Access
1 Citations
1,371 Views
13 Pages

8 June 2024

The elasto-optic properties of liquids on the basis of the first principles of acousto-optics were theoretically investigated. A relationship for calculating the elasto-optic constant of liquids using only the refractive index was obtained. The refra...

  • Review
  • Open Access
24 Citations
4,922 Views
26 Pages

11 September 2023

The thermo-optic effect is a crucial driving mechanism for optical devices. The application of the thermo-optic effect in integrated photonics has received extensive investigation, with continuous progress in the performance and fabrication processes...

  • Review
  • Open Access
47 Citations
5,844 Views
27 Pages

Oxidative Stress in Optic Neuropathies

  • Berta Sanz-Morello,
  • Hamid Ahmadi,
  • Rupali Vohra,
  • Sarkis Saruhanian,
  • Kristine Karla Freude,
  • Steffen Hamann and
  • Miriam Kolko

28 September 2021

Increasing evidence indicates that changes in the redox system may contribute to the pathogenesis of multiple optic neuropathies. Optic neuropathies are characterized by the neurodegeneration of the inner-most retinal neurons, the retinal ganglion ce...

  • Article
  • Open Access
3 Citations
2,914 Views
10 Pages

Mitochondrial Triglyceride Dysregulation in Optic Nerves Following Indirect Traumatic Optic Neuropathy

  • Muhammad Z. Chauhan,
  • Joseph G. Chacko,
  • Alireza Ghaffarieh,
  • Chloe M. Moulin,
  • Daniel Pelaez,
  • Sami H. Uwaydat and
  • Sanjoy K. Bhattacharya

15 December 2022

The purpose of this work is to identify mitochondrial optic nerve (ON) lipid alterations associated with sonication-induced traumatic optic neuropathy (TON). Briefly, a mouse model of indirect TON was generated using sound energy concentrated focally...

  • Article
  • Open Access
14 Citations
4,950 Views
18 Pages

Regional Gene Expression in the Retina, Optic Nerve Head, and Optic Nerve of Mice with Optic Nerve Crush and Experimental Glaucoma

  • Casey J. Keuthan,
  • Julie A. Schaub,
  • Meihan Wei,
  • Weixiang Fang,
  • Sarah Quillen,
  • Elizabeth Kimball,
  • Thomas V. Johnson,
  • Hongkai Ji,
  • Donald J. Zack and
  • Harry A. Quigley

6 September 2023

A major risk factor for glaucomatous optic neuropathy is the level of intraocular pressure (IOP), which can lead to retinal ganglion cell axon injury and cell death. The optic nerve has a rostral unmyelinated portion at the optic nerve head followed...

  • Article
  • Open Access
52 Citations
5,797 Views
16 Pages

31 May 2020

In this paper, we propose a method for localizing the optic nerve head and segmenting the optic disc/cup in retinal fundus images. The approach is based on a simple two-stage Mask-RCNN compared to sophisticated methods that represent the state-of-the...

  • Article
  • Open Access
9 Citations
3,412 Views
11 Pages

Optical Microfiber All-Optical Phase Modulator for Fiber Optic Hydrophone

  • Minwei Li,
  • Yang Yu,
  • Yang Lu,
  • Xiaoyang Hu,
  • Yaorong Wang,
  • Shangpeng Qin,
  • Junyang Lu,
  • Junbo Yang and
  • Zhenrong Zhang

28 August 2021

In order to meet the needs of phase generated carrier (PGC) demodulation technology for interferometric fiber optic hydrophones, we proposed an optical microfiber all-optical phase modulator (OMAOPM) based on the photo-induced thermal phase shift eff...

  • Review
  • Open Access
1 Citations
7,097 Views
15 Pages

Hereditary Optic Neuropathies: An Updated Review

  • Samuel K. Lee,
  • Caroline Mura,
  • Nicolas J. Abreu,
  • Janet C. Rucker,
  • Steven L. Galetta,
  • Laura J. Balcer and
  • Scott N. Grossman

Hereditary optic neuropathies (HONs) are a class of genetic disorders that may lead to vision loss due to either acute or progressive injury to the optic nerve. Although HONs may commonly manifest as isolated optic atrophy, these disorders can also h...

  • Article
  • Open Access
6 Citations
2,304 Views
13 Pages

Glaucoma represents a significant global contributor to blindness. Accurately segmenting the optic disc (OD) and optic cup (OC) to obtain precise CDR is essential for effective screening. However, existing convolutional neural network (CNN)-based seg...

  • Article
  • Open Access
21 Citations
9,225 Views
10 Pages

Fiber-Optic Pyrometer with Optically Powered Switch for Temperature Measurements

  • Carmen Vázquez,
  • Sandra Pérez-Prieto,
  • Juan D. López-Cardona,
  • Alberto Tapetado,
  • Enrique Blanco,
  • Jorge Moreno-López,
  • David S. Montero and
  • Pedro C. Lallana

6 February 2018

We report the experimental results on a new infrared fiber-optic pyrometer for very localized and high-speed temperature measurements ranging from 170 to 530 °C using low-noise photodetectors and high-gain transimpedance amplifiers with a single gain...

  • Proceeding Paper
  • Open Access
589 Views
7 Pages

The Thermo-Optic Discrimination of an Aqueous Solution Composition Using a Multimodal Interference Fiber Optic Sensor

  • Ruth K. Delgadillo-González,
  • Nailea Mar-Abundis,
  • René F. Domínguez-Cruz,
  • Federico Ampudia-Ramírez,
  • Yadira A. Fuentes-Rubio and
  • José R. Guzmán-Sepúlveda

Fiber optics sensors based on multimodal interference (MMI) have proven effective for refractometry of liquid samples. Here, we extend these capabilities to demonstrate that aqueous solutions with a similar refractive index (RI), which at room temper...

  • Article
  • Open Access
1,424 Views
14 Pages

Early Macular Ganglion Cell Loss in Leber Hereditary Optic Neuropathy, an Optical Coherence Tomography Biomarker to Differentiate Optic Neuritis

  • Julian A. Zimmermann,
  • Martin Dominik Leclaire,
  • Jens Julian Storp,
  • Tobias J. Brix,
  • Nicole Eter,
  • Julia Krämer and
  • Julia Biermann

15 March 2025

Background/Objectives: Leber hereditary optic neuropathy (LHON) is often misdiagnosed in its early stages as idiopathic single isolated optic neuritis (SION) or multiple-sclerosis-associated optic neuritis (MS-ON) due to the young age of the patients...

  • Case Report
  • Open Access
1 Citations
3,485 Views
9 Pages

Optic Nerve Glioblastoma with Optic Chiasm Involvement: A Case Report and a Brief Literature Review

  • Artis Brokāns,
  • Jūlija Dolgopolova,
  • Agnis Saulītis,
  • Uldis Spulle,
  • Kristaps Rancāns,
  • Dairis Meiers,
  • Sigita Hasnere and
  • Arturs Balodis

14 October 2024

Background: optic nerve glioblastoma is an uncommon pathology. The optic chiasm, optic tract, or optic nerves are possible places from which the tumor can originate. Most of the neuroimaging findings are nonspecific. To confirm the diagnosis, a biops...

  • Article
  • Open Access
16 Citations
5,872 Views
16 Pages

4 May 2019

Fiber-optics sensors using interrogation based on incoherent optical frequency-domain reflectometry (I-OFDR) offer benefits such as the high stability of interference in the radio-frequency (RF) domain and the high SNR due to narrowband RF detection....

  • Entry
  • Open Access
10 Citations
16,436 Views
14 Pages

Traumatic Optic Neuropathy: Update on Management

  • Mohammad Reza Hosseini Siyanaki,
  • Mohammed A. Azab and
  • Brandon Lucke-Wold

13 January 2023

Traumatic optic neuropathy is one of the causes of visual loss caused by blunt or penetrating head trauma and is classified as both direct and indirect. Clinical history and examination findings usually allow for the diagnosis of traumatic optic neur...

  • Review
  • Open Access
7 Citations
261 Views
11 Pages

Optic Nerve Monitoring

  • Paul Schumann,
  • Horst Kokemüller,
  • Frank Tavassol,
  • Daniel Lindhorst,
  • Juliana Lemound,
  • Harald Essig,
  • Martin Rücker and
  • Nils-Claudius Gellrich

Orbital and anterior skull base surgery is generally performed close to the prechiasmatic visual pathway, and clear strategies for detecting and handling visual pathway damage are essential. To overcome the common problem of a missed clinical examina...

  • Review
  • Open Access
5 Citations
4,837 Views
20 Pages

The Optic Nerve at Stake: Update on Environmental Factors Modulating Expression of Leber’s Hereditary Optic Neuropathy

  • Pierre Layrolle,
  • Christophe Orssaud,
  • Maryse Leleu,
  • Pierre Payoux and
  • Stéphane Chavanas

Optic neuropathies are characterized by the degeneration of the optic nerves and represent a considerable individual and societal burden. Notably, Leber’s hereditary optic neuropathy (LHON) is a devastating vision disease caused by mitochondria...

  • Article
  • Open Access
6 Citations
4,480 Views
7 Pages

9 January 2019

We have demonstrated a high pulse energy and high optic–optic efficiency double-pass picosecond (ps) master oscillator power amplifier system of 1064 nm at a pulse repetition rate of 500 kHz. A 500 kHz, 7.68 μJ picosecond laser is used as the seed la...

  • Review
  • Open Access
4 Citations
8,139 Views
27 Pages

9 October 2012

Organic fluorinated materials demonstrate their excellent electro-optic properties and versatility for technological applications. The partial substitution of hydrogen with fluorine in carbon-halides bounds allows the reduction of absorption losses a...

  • Review
  • Open Access
61 Citations
18,179 Views
42 Pages

Recent Developments in Micro-Structured Fiber Optic Sensors

  • Yanping Xu,
  • Ping Lu,
  • Liang Chen and
  • Xiaoyi Bao

10 January 2017

Recent developments in fiber-optic sensing have involved booming research in the design and manufacturing of novel micro-structured optical fiber devices. From the conventional tapered fiber architectures to the novel micro-machined devices by advanc...

  • Review
  • Open Access
3 Citations
4,925 Views
9 Pages

Congenital Optic Disc Anomalies: Insights from Multimodal Imaging

  • Gilda Cennamo,
  • Michele Rinaldi,
  • Marina Concilio and
  • Ciro Costagliola

6 March 2024

In this comprehensive review, we delve into the significance of multimodal imaging in diagnosing and managing complications of congenital optic disc anomalies. While the fundus examination is the gold standard tool in the diagnosis of these pathologi...

  • Article
  • Open Access
24 Citations
11,891 Views
9 Pages

19 June 2021

We aimed to systematically examine the optic nerve head anatomy in patients with idiopathic intracranial hypertension (IIH) using a standardized optical coherence tomography (OCT) protocol. The study retrospectively included 32 patients diagnosed fro...

  • Review
  • Open Access
1,573 Views
27 Pages

Applications of Optical Coherence Tomography in Optic Nerve Head Diseases: A Narrative Review

  • Mohamed M. Khodeiry,
  • Elizabeth Colvin,
  • Mohammad Ayoubi,
  • Ximena Mendoza and
  • Maja Kostic

26 November 2025

Optical coherence tomography (OCT) is a non-invasive imaging tool that is currently used in the evaluation and management of neuro-ophthalmic disorders. The detailed ability to visualize the optic nerve head, peripapillary retinal nerve fiber layer,...

  • Review
  • Open Access
44 Citations
8,573 Views
54 Pages

Oxidative Stress: A Suitable Therapeutic Target for Optic Nerve Diseases?

  • Francesco Buonfiglio,
  • Elsa Wilma Böhm,
  • Norbert Pfeiffer and
  • Adrian Gericke

Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology of these disorders can vary significantly, but emerging research hig...

  • Communication
  • Open Access
1 Citations
1,830 Views
11 Pages

Generation of Flat Optical Frequency Comb Using Cascaded Electro-Optic Modulators

  • Wei Lin,
  • Bowen Zhu,
  • Keqi Cao,
  • Hang Yu,
  • Xinyan Zhang,
  • Jia Chen and
  • Yu Liu

Optical frequency combs have been widely used in spectrum analysis, coherent optical communication, and accurate distance measurement. We propose a straightforward method to improve the flatness of optical frequency combs. First, we derived the outpu...

  • Review
  • Open Access
915 Views
15 Pages

Therapeutic Approaches for Toxic Optic Neuropathies: Insights from Methanol-Induced Optic Neuropathy and NAION Treatments

  • Lorenzo Verriello,
  • Giada Pauletto,
  • Marco Zeppieri,
  • Simone Lorenzut,
  • Chiara Bertolotti,
  • Caterina Gagliano,
  • Fabiana D’Esposito,
  • Matteo Capobianco and
  • Marieme Khouyyi

13 November 2025

Background/Objectives: Toxic optic neuropathy (TON) represents a spectrum of optic nerve damage caused by exposure to toxins, including drugs, alcohol, and industrial chemicals. It is characterized by progressive vision loss, dyschromatopsia, and opt...

  • Review
  • Open Access
55 Citations
11 Pages

Traumatic Optic Neuropathy: A Review

  • Arjunan Muthu Kumaran,
  • Gangadhara Sundar and
  • Thiam Chye Lim

The aim of this article is to evaluate current literature on investigation and management of traumatic optic neuropathy (TON), propose recommendations for diagnosis and management, and explore novel future treatments. TON, though uncommon, causes sub...

  • Article
  • Open Access
353 Views
14 Pages

25 November 2025

The long-term operational stability of a fiber optic current transformer (FOCT) is critically dependent on the integrity of its internal fiber optic loop. Conventional testing methods often fall short in providing high-precision, spatially resolved d...

  • Article
  • Open Access
6 Citations
2,593 Views
18 Pages

Fiber-Optic System for Monitoring Pit Collapse Prevention

  • Yelena Neshina,
  • Ali Mekhtiyev,
  • Valeriy Kalytka,
  • Nurbol Kaliaskarov,
  • Olga Galtseva and
  • Ilyas Kazambayev

29 May 2024

Currently, there are many enterprises involved in extracting and processing of primary raw materials. The danger of working in this industry consists in the formation of cracks in rocks of the pit side slopes, which can lead to destruction. This arti...

  • Review
  • Open Access
2,481 Views
13 Pages

Ocular Ultrasound in the Diagnosis of Optic Neuropathies: A Review of the Literature

  • Alessia Coppola,
  • Giulia Abbinante,
  • Ilaria De Pascale,
  • Vincenzo Gagliardi,
  • Giulio Salerno,
  • Alfonso Pellegrino and
  • Livio Vitiello

8 September 2024

Background: Optic neuropathies represent one of the most frequent causes of vision loss, and they can manifest alone or in conjunction with neurological or systemic symptoms and signs. In recent years, the diagnostic techniques used to detect optic n...

  • Article
  • Open Access
21 Citations
9,112 Views
13 Pages

Durability Tests of a Fiber Optic Corrosion Sensor

  • Kai Tai Wan and
  • Christopher K.Y. Leung

16 March 2012

Steel corrosion is a major cause of degradation in reinforced concrete structures, and there is a need to develop cost-effective methods to detect the initiation of corrosion in such structures. This paper presents a low cost, easy to use fiber optic...

  • Review
  • Open Access
63 Citations
11,032 Views
23 Pages

Optical Fiber Networks for Remote Fiber Optic Sensors

  • Montserrat Fernandez-Vallejo and
  • Manuel Lopez-Amo

26 March 2012

This paper presents an overview of optical fiber sensor networks for remote sensing. Firstly, the state of the art of remote fiber sensor systems has been considered. We have summarized the great evolution of these systems in recent years; this progr...

  • Review
  • Open Access
9 Citations
5,117 Views
22 Pages

Suppression Method of Optical Noises in Resonator-Integrated Optic Gyroscopes

  • Xuebao Kuai,
  • Lei Wei,
  • Fuhua Yang,
  • Wei Yan,
  • Zhaofeng Li and
  • Xiaodong Wang

9 April 2022

Resonator-integrated optical gyroscopes have advantages such as all-solid-state, on-chip integration, miniaturized structure, and high precision. However, many factors deteriorate the performance and push it far from the shot-noise limited theoretica...

  • Case Report
  • Open Access
5 Citations
1 Views
2 Pages

Sphenochoanal Polyps and the Optic Nerve

  • Tolgar Lütfi Kumral,
  • Güven Yildirim and
  • Yavuz Uyar

9 January 2012

Isolated sphenoid pathology is uncommon. Nasal polyps that originate from the anterior wall of the sphenoid sinus and reach the nasopharynx are called sphenochoanal polyps. The atypical location of sphenochoanal polyps leads to misdiagnosis, and surg...

  • Article
  • Open Access
7 Citations
4,347 Views
15 Pages

Thermo-Optic Response and Optical Bistablility of Integrated High-Index Doped Silica Ring Resonators

  • Junkai Hu,
  • Jiayang Wu,
  • Di Jin,
  • Sai Tak Chu,
  • Brent E. Little,
  • Duan Huang,
  • Roberto Morandotti and
  • David J. Moss

11 December 2023

The engineering of thermo-optic effects has found broad applications in integrated photonic devices, facilitating efficient light manipulation to achieve various functionalities. Here, we perform both an experimental characterization and a theoretica...

  • Review
  • Open Access
5 Citations
6,499 Views
28 Pages

Tapered optical fibers have continuously evolved in areas such as distributed sensing and laser generation in recent years. Their high sensitivity, ease of integration, and real-time monitoring capabilities have positioned them as a focal point in op...

  • Review
  • Open Access
9 Citations
4,042 Views
14 Pages

Uncovering the Genetics and Physiology behind Optic Neuritis

  • Ilaria Del Negro,
  • Giada Pauletto,
  • Lorenzo Verriello,
  • Leopoldo Spadea,
  • Carlo Salati,
  • Tamara Ius and
  • Marco Zeppieri

9 December 2023

Optic neuritis (ON) is an inflammatory condition affecting the optic nerve, leading to vision impairment and potential vision loss. This manuscript aims to provide a comprehensive review of the current understanding of ON, including its definition, e...

  • Review
  • Open Access
47 Citations
8,134 Views
27 Pages

Hybrid Plasmonic Fiber-Optic Sensors

  • Miao Qi,
  • Nancy Meng Ying Zhang,
  • Kaiwei Li,
  • Swee Chuan Tjin and
  • Lei Wei

8 June 2020

With the increasing demand of achieving comprehensive perception in every aspect of life, optical fibers have shown great potential in various applications due to their highly-sensitive, highly-integrated, flexible and real-time sensing capabilities....

  • Article
  • Open Access
19 Citations
3,833 Views
12 Pages

18 January 2021

This paper presents the results of theoretical and experimental studies of anisotropic acousto-optic interaction in a spatially periodical acoustic field created by a phased-array transducer with antiphase excitation of adjacent sections. In this cas...

  • Communication
  • Open Access
5 Citations
3,487 Views
9 Pages

Fiber Optic Load Cells with Enhanced Sensitivity by Optical Vernier Effect

  • Tiago Paixão,
  • Ricardo Ferreira,
  • M. Fátima Domingues and
  • Paulo Antunes

20 November 2021

Developing technologies capable of constantly assessing and optimizing day-to-day activities has been a research priority for several years. A key factor in such technologies is the use of highly sensitive sensors to monitor in real-time numerous par...

  • Article
  • Open Access
29 Citations
5,645 Views
17 Pages

11 October 2019

Glaucoma is a serious eye disease that can cause permanent blindness and is difficult to diagnose early. Optic disc (OD) and optic cup (OC) play a pivotal role in the screening of glaucoma. Therefore, accurate segmentation of OD and OC from fundus im...

  • Communication
  • Open Access
1,827 Views
17 Pages

Low-Coherence Integrated Optical Interferometer for Fibre Optic Sensors

  • Petr Volkov,
  • Alexander Bobrov,
  • Oleg Vyazankin,
  • Alexey Gorshkov,
  • Alexander Goryunov,
  • Glafira Lemeshevskaya,
  • Andrey Lukyanov,
  • Aleksey Nezhdanov,
  • Daniil Semikov and
  • Kirill Sidorenko

27 December 2024

This paper proposes and implements a novel scheme for recording signals from fibre optic sensors based on tandem low-coherence interferometry with an integrated optical reference interferometer. The circuit allows precision control of the phase shift...

  • Article
  • Open Access
5 Citations
3,128 Views
11 Pages

Measurement of the Quadratic Electro-Optic Coefficient of KTN Crystal with an Electro-Optic Modulation System in the Presence of Polar Nano-Regions

  • Lie-Kun Yang,
  • Bing Liu,
  • Pan-Yu Qiao,
  • Hua-Jian Yu,
  • Xu-Ping Wang,
  • Jing Li,
  • Yu-Guo Yang,
  • Yuan-Yuan Zhang,
  • Cheng-Cheng Qiu and
  • Hua-Di Zhang

13 October 2021

An electro-optic modulation system was adopted for measuring the quadratic electro-optic coefficient of KTN crystal. Theoretical analysis and experimental results verified the feasibility of this method. The quadratic electro-optic coefficient of a K...

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