Inflammation in Neuro-Oncological Diseases and in Neuro-Vascular Diseases
Topic Information
Dear Colleagues,
Neuroinflammation plays an essential role in tumorigenesis, malignant progression, vascular inflammation, and clinical symptomatology. The central nervous system (CNS) microenvironment has a significant role in those pathophysiological processes. Interleukins, immune infiltrates, cyclooxygenases, etc. are important drivers in those diseases. On a cellular basis, tumor-associated macrophages, reactive astrocytes, leukocytes, platelets, and further contributors of the inflammatory response influence diseases’ progression and response to treatment. Several preclinical and clinical trials investigating neuroinflammation and pharmacological modulation of the immune system have improved our understanding of the immune response in neuro-oncological and neurovascular diseases. This Topic Issue will focus on preclinical and clinical data regarding the interaction between neuro-oncological or neurovascular diseases and neuroinflammation.
Prof. Dr. Erdem Güresir
Dr. Johannes Wach
Dr. Martin Vychopen
Topic Editors
Keywords
- inflammation
- neuro-oncology
- brain tumors
- interleukins
- neurovascular
- subarachnoid hemorrhage
- macrophages
- immune microenvironment
- inflammatory pathways
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