Biomolecular recognition using a multivalent strategy has been successfully applied, this last decade on several biological targets, especially carbohydrate-processing enzymes, proteases, and phosphorylases. This strategy is based on the fact that mu...
Aptamers are short and single-stranded DNA or RNA molecules with highly programmable structures that give them the ability to interact specifically with a large variety of targets, including proteins, cells, and small molecules. Multivalent aptamers...
Recently, the strategy of multivalency has been widely employed to design glycosidase inhibitors, as glycomimetic clusters often induce marked enzyme inhibition relative to monovalent analogs. Polyhydroxylated pyrrolidines, one of the most studied cl...
In this paper, various features of a new class of normalized multivalent harmonic functions in the open unit disk are analyzed, including bounds on coefficients, growth estimations, starlikeness and convexity radii. It is further demonstrated that th...
Several biological macromolecules adopt bivalent or multivalent interactions to perform various cellular processes. In this regard, the development of molecular constructs presenting multiple ligands in a specific manner is becoming crucial for the u...
Rapidly growing global demand for high energy density rechargeable batteries has driven the research toward developing new chemistries and battery systems beyond Li-ion batteries. Due to the advantages of delivering more than one electron and giving...
Discotic molecules, which self-assemble in water into columnar supramolecular polymers, emerged as an alternative platform for the organization of proteins. Here, a monovalent discotic decorated with one single biotin was synthesized to study the se...
Many biopolymers exhibit a strong complexing ability for multivalent ions. Often such ions form ionic bridges between the polymer chains. This leads to the formation of ionic cross linked networks and supermolecular structures, thus promoting the mod...
Multivalency is a strategy commonly used by medicinal carbohydrate chemists to increase the affinity of carbohydrate-based small molecules for their protein targets. Although this approach has been very successful in enhancing binding to isolated car...
Multivalent protein-carbohydrate interactions that are mediated by sugar-binding proteins, i.e., lectins, have been implicated in a myriad of intercellular recognition processes associated with tumor progression such as galectin-mediated cancer cell...
In addition to the conventional Isothermal Titration Calorimetry (ITC), kinetic ITC (kinITC) not only gains thermodynamic information, but also kinetic data from a biochemical binding process. Moreover, kinITC gives insights into reactions consisting...
This paper presents a novel symmetric q-analogue differential operator designed for meromorphic multivalent functions analytic in the punctured open unit disk. Employing this operator, a new family of meromorphic multivalent functions is proposed and...
Many researchers have defined the q-analogous of differential and integral operators for analytic functions using the concept of quantum calculus in the geometric function theory. In this study, we conduct a comprehensive investigation to identify th...
Nucleic acid aptamers generated through an in vitro selection are currently extensively applied as very valuable biomolecular tools thanks to their prominent advantages. Diversity of spatial structures, ease of production through chemical synthesis a...
A class of p-valent functions of complex order is defined with the primary motive of unifying the concept of prestarlike functions with various other classes of multivalent functions. Interesting properties such as inclusion relations, integral repre...
Starlike functions have gained popularity both in literature and in usage over the past decade. In this paper, our aim is to examine some useful problems dealing with q-starlike functions. These include the convolution problem, sufficiency criteria,...
Here, the controlled formation of platinum nanoparticles (PtNPs) and silver nanoparticles (AgNPs) using amine-functionalized multivalent ligands are reported. The effects of reaction temperature and ligand multivalency on the growth kinetics, size, a...
The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulting in the COVID-19 pandemic, has profoundly impacted global healthcare systems and the trajectory of economic advancement. As nations grapple with the far-reach...
It has been reported that the novel coronavirus (COVID-19) has caused more than 286 million cases and 5.4 million deaths to date. Several strategies have been implemented globally, such as social distancing and the development of the vaccines. Severa...
Complex coacervation is an emerging liquid/liquid phase separation (LLPS) phenomenon that behaves as a membrane-less organelle in living cells. Yet while one of the critical factors for complex coacervation is temperature, little analysis and researc...
In this article, we use the concept of symmetric q-calculus and convolution in order to define a symmetric q-differential operator for multivalent functions. This operator is an extension of the classical Ruscheweyh differential operator. By using th...
The interplay between special functions and geometric function theory continues to inspire significant advances in the study of analytic and multivalent functions. In this work, we introduce and investigate several new subfamilies of multivalent func...
In our present investigation, we extend the idea of q-symmetric derivative operators to multivalent functions and then define a new subclass of multivalent q-starlike functions. For this newly defined function class, we discuss some useful properties...
We used the concept of quantum calculus (Jackson’s calculus) in a recent note to develop an extended class of multivalent functions on the open unit disk. Convexity and star-likeness properties are obtained by establishing conditions for this c...
In this article, we introduce a new class of multivalent analytic functions associated with petal-shape region. Furthermore, some useful properties, such as the Fekete–Szegö inequality, and their consequences for some special cases are discussed. For...
SARS-CoV-2 new waves are primarily caused by changes to the spike protein (S), which can substantially decrease the efficacy of vaccines. Therefore, we tested several multivalent mRNA-LNP vaccines, targeting the full-length S proteins of different va...
This review discusses the role of galectin-1 in the tumor microenvironment. First, the structure and function of galectin-1 are discussed. Galectin-1, a member of the galectin family of lectins, is a functionally dimeric galactoside-binding protein....
We define a function to unify the well-known class of Janowski functions with a class of spirallike functions of reciprocal order. We focus on the impact of defined function on various conic regions which are symmetric with respect to the real axis....
In the present research paper, our aim is to introduce a new subfamily of p-valent (multivalent) functions of reciprocal order. We investigate sufficiency criterion for such defined family.
In this article, by utilizing the theory of quantum (or q-) calculus, we define a new subclass of analytic and multivalent (or p-valent) functions class
Reverse electrodialysis (RED) represents one of the most promising membrane-based technologies for clean and renewable energy production from mixing water solutions. However, the presence of multivalent ions in natural water drastically reduces syste...
LCB1 is a computationally designed three-helix miniprotein that precisely targets the spike (S) receptor-binding motif (RBM) of SARS-CoV-2, exhibiting remarkable antiviral efficacy; however, emerging SARS-CoV-2 variants could substantially compromise...
Gonorrhea is one of the most common, but still hidden and insidious, sexually transmitted diseases caused by Neisseria gonorrhoeae (gonococci). However, the diagnosis and treatment of gonorrhea are hampered by antigenic variability among gonococci, t...
Using convolution (or Hadamard product), we define the El-Ashwah and Drbuk linear operator, which is a multivalent function in the unit disk
In this article we introduced and studied some inclusion properties for new subclasses of multivalent analytic functions defined by using the q-derivative operator. With the aid of the Jackson q-derivative we defined two new operators that generalize...
Hand-foot-and-mouth disease (HFMD) is an infectious disease of children caused by more than 20 types of enteroviruses, with most cases recovering spontaneously within approximately one week. Severe HFMD in individual children develops rapidly, leadin...
The lithium ion battery, with its high energy density and low reduction potential, continues to enchant researchers and dominate the landscape of energy storage systems development. However, the demands of technology in modern society have begun to r...
In this paper, we define two classes of meromorphic multivalent functions in the punctured disc
This paper examines two subclasses of multivalent analytic functions defined with higher-order derivatives. These classes of functions are generalizations of several known subclasses that have been studied in separate works. Moreover, we find several...
Interactions between glycans and proteins have tremendous impact in biomolecular interactions. They are important for cell–cell interactions, proliferation and much more. Here, we emphasize the glycan-mediated interactions between pathogens and...
Germanium, a promising electrode material for high-capacity lithium ion batteries (LIBs) anodes, attracted much attention because of its large capacity and remarkably fast charge/discharge kinetics. Multivalent-ion batteries are of interest as potent...
Salmonella poses a severe global threat to food safety and public health, necessitating rapid, sensitive, and reliable detection methods. Conventional techniques often suffer from complexity, time consumption, cost, or limited sensitivity. To address...
In the present research paper, our aim is to introduce a new subfamily of meromorphic p-valent (multivalent) functions. Moreover, we investigate sufficiency criterion for such defined family.
A concise synthetic route from methylmalonate to a tetravalent aliphatic scaffold has been developed. The ensuing tetra-tethered derivative is equipped with two hydroxyl groups, as well as orthogonal alkene and alkyne functionalities. The usefulness...
A new subclass
In this paper, we consider some differential subordination and superordination results for analytic and multivalent functions in the open unit disk related to Borel distribution through investigating appropriate families of admissible functions. Thes...
The increasing demand for sustainable and high-performance energy storage underscores the limitations of lithium-ion batteries (LIBs), notably in terms of finite resources, safety issues, and rising costs. Multivalent metal-ion batteries (MMIBs)&mdas...
Multivalent metal ion (Mg2+, Zn2+, Ca2+, and Al3+) batteries (MMIBs) emerged as promising technologies for large-scale energy storage systems in recent years due to the abundant metal reserves in the Earth’s crust and potentially low cost. Howe...
mRNA vaccines were highly effective in response to the COVID-19 pandemic, making them an attractive platform to address cancers and other infectious diseases. Many new mRNA vaccines in development are multivalent, which represents a difficulty for th...
This article aims to significantly advance geometric function theory by providing a valuable contribution to analytic and multivalent functions. It focuses on differential subordination and superordination, which characterize the interactions between...
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