Special Issue "Synthesis and Biological Applications of Glycoconjugates Ⅱ"
Deadline for manuscript submissions: closed (1 April 2019).
Interests: glycoconjugates; enzyme cascade reactions; chemo-enzymatic synthesis; glycosyltransferases; nucleotide sugars; galectins; lectins; glycopolymers; biosensors; biomaterials
Special Issues and Collections in MDPI journals
Glycoconjugates (glycoproteins, glycolipids, proteoglycans) are involved in numerous biological recognition events. Their glycans encode the specific information to trigger protein–glycan interactions. Intercellular crosstalk and pathogen–host interactions are examples and are directly related to the vast chemical diversity of glycan structures. Glycan synthesis via chemical and/or enzymatic approaches are therefore challenging. Novel and efficient procedures for glycan-based products need to be developed and optimized. Multi-enzyme cascade reactions are key for the production of glycans in a larger scale. Protein engineering of enzymes serve to tailor biocatalysts with favorable and novel properties. Most importantly, the combination of chemo- and biocatalysis expands the spectrum of novel synthetic routes. In this way, complex glycans and neo-glycoconjugates will be accessible for biological applications. Multivalency is a key factor for decoding glycan information by carbohydrate recognizing molecules such as lectins and antibodies leading to many applications in biomedicine, biomaterial research, and advanced material sciences. Examples have been seen already in the first Special Issue “Synthesis and Biological Applications of Glycoconjugates” in Molecules in 2017.
I cordially invite you to contribute and share your recent research results in the upcoming second Special Issue on all aspects of the synthesis and biological applications of glycoconjugates.
Prof. Dr. Lothar Elling
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- cascade reactions
- chemo-enzymatic synthesis
- glycoconjugates in tissue engineering
- glycoconjugates of the microbiome
- glycoconjugates in host-pathogen interaction
- Synthesis and Biological Applications of Glycoconjugates in Molecules (7 articles)