Gel fibers prepared based on microfluidic laminar flow technology have important research value in constructing biomimetic scaffolds and tissue engineering. The key point of microfluidic laminar flow technology is to find the appropriate fluid flow r...
Microfluidic reactors have remarkably promoted the synthesis and investigation of advanced nanomaterials due to their continuous mode and accelerated heat/mass transfer. Notably, segmented microfluidic flow reactors (SMFRs) are an important class of...
Materials science is a fast-evolving area that aims to uncover functional materials with ever more sophisticated properties and functions. For this to happen, new methodologies for materials synthesis, optimization, and preparation are desired. In th...
This review gives an overview of passive constant flow regulators dedicated to microfluidic applications. Without external control and energy consumption, these devices deliver a constant flow rate regardless of pressure variations, making them very...
A passive microvalve has appealing advantages in cost-effective and miniaturized microfluidic applications. In this work, we present a passive flow regulatory device for enhanced flow control in a microfluidic environment. The device was integrated w...
To bring to bear the power of centrifugal microfluidics on vertical flow immunoassays, control of flow orthogonally through nanoporous membranes is essential. The on-disc approach described here leverages the rapid print-cut-laminate (PCL) disc fabri...
Membraneless microfluidic fuel cells (MMFCs) are being studied extensively as an alternative to batteries and conventional membrane fuel cells because of their simple functioning and lower manufacturing cost. MMFCs use the laminar flow of reactant sp...
A novel approach to protein quantification utilizing a microfluidic platform activated by a magnetic assembly of functionalized magnetic beads around soft magnetic capture centers is presented. Functionalized magnetic beads, known for their high surf...
Capillary-driven microfluidic chips have emerged as promising platforms for point-of-care diagnostics, offering portable, inexpensive, and pump-free operation. Accurate tracking of cell flow in these systems is vital for quantitative applications suc...
Continuous-flow microfluidic biochips are a type of biochip technology based on microfluidic channels that enable various biological experiments and analyses to be performed on a tiny chip. They have the advantages of a high throughput, high sensitiv...
Droplet microfluidics involving non-Newtonian fluids is of great importance in both fundamental mechanisms and practical applications. In the present study, breakup dynamics in droplet generation of semi-dilute polymer solutions in a microfluidic flo...
Single-cell analysis commonly requires the confinement of cell suspensions in an analysis chamber or the precise positioning of single cells in small channels. Hydrodynamic flow focusing has been broadly utilized to achieve stream confinement in micr...
This article reviews recent developments in microfluidic impedance flow cytometry for high-throughput electrical property characterization of single cells. Four major perspectives of microfluidic impedance flow cytometry for single-cell characterizat...
This computational study investigates the sensing and actuating behavior of a pH-sensitive hydrogel-based microfluidic flow controller. This hydrogel-based flow controller has inherent advantage in its unique stimuli-sensitive properties, removing th...
The detection of proteins plays a key role in disease diagnosis and drug development. For this, we numerically investigated a novel microfluidic motor actuated by an induced-charge electro-osmotic (ICEO) whirling flow. An alternating current–fl...
Microplastics as micropollutants are widely spread in aquatic areas that can have a toxic effect on aquatic life. To reduce the potential risk they pose, it is essential to detect the microplastics and the source of the contamination of the environme...
A cell-in-droplet encapsulation using Dean flow in a spiral microfluidic device was applied to separate microalgae. In recent years, researchers have been interested in separating micro particles using microfluidic chips because of its great advantag...
This research is dedicated to optimizing the design of microfluidic cells to minimize mass transfer effects and ensure a uniform flow field distribution, which is essential for accurate SPR array detection. Employing finite element simulations, this...
A key aspect of microfluidic processes is their ability to perform chemical reactions in small volumes under continuous flow. However, a continuous process requires stable reagent flow over a prolonged period. This can be challenging in microfluidic...
Increasing research efforts have been recently devoted to the coupling of microfluidic chip-integrated ionization sources to mass spectrometry (MS). Considering the limitations of microfluidic chips coupled with MS such as liquid spreading, dead volu...
Drops contained in an immiscible liquid phase are attractive as microreactors, enabling sound statistical analysis of reactions performed on ensembles of samples in a microfluidic device. Many applications have specific requirements for the values of...
A microfluidic passive valve (MPV) is important for precise flow control, and it determines the reliability of the microfluidic system. In this paper, a novel MPV capable of delivering a constant flow rate independently of inlet pressure changes is p...
This article first reviews scientific meanings of single-cell analysis by highlighting two key scientific problems: landscape reconstruction of cellular identities during dynamic immune processes and mechanisms of tumor origin and evolution. Secondly...
This work characterizes the orientation behavior of nematic liquid crystals in pressure-driven flows of microfluidic channels at interfaces between the flow and microchannel walls. The impact of flow velocity and microchannel geometry on the orientat...
The capture of individual cells using microfluidic chips represents a widely adopted and efficient approach for investigating the biochemical microenvironment of singular cells. While conventional methods reliant on boundary effects pose challenges i...
This paper presents a practical flow-through method to separate anisole and ethyl phenylacetate, respectively, from a polystyrene mixture. The microfluidic separation uses different diffusive dynamics of the substances transverse to the lamination fl...
A dual beam optical coherence tomography (OCT) instrument has been developed for flow measurement that offers advantages over microscope derived imaging techniques. It requires only a single optical access port, allows simultaneous imaging of the mic...
Measuring RBC aggregation can be considered as a valuable tool for detecting pathological diseases. Most previous methods need to stop and run blood flows periodically. Thus, it is impossible to probe RBC aggregation in continuously varying infusion...
Eliminating clogging in capillary tube reactors is critical but challenging for enabling continuous-flow microfluidic synthesis of nanoparticles. Creating immiscible segments in a microfluidic flow is a promising approach to maintaining a continuous...
A passive pump consisting of integrated vertical capillaries has been developed for a microfluidic chip as an useful component with an excellent flow volume and flow rate. A fluidic chip built into a passive pump was used by connecting the bottoms of...
Microfluidics are crucial for managing small-volume analytical solutions for various applications, such as disease diagnostics, drug efficacy testing, chemical analysis, and water quality monitoring. The precise control of flow control devices can ge...
This study evaluates the performance of continuous flow and drop-based microfluidic devices for the synthesis of silver nanoparticles (AgNPs) under identical hydrodynamic and chemical conditions. Flows at low values of Dean number (De < 1) were in...
In this paper we study the dynamics of single cells encapsulated in water-in-oil emulsions in a microchannel. The flow field of a microfluidic channel is coupled to the internal flow field of a droplet through viscous traction at the interface, resul...
Recent developments in the field of additive manufacturing processes have led to tremendous technological progress and opened directions for the field of microfluidics. For instance, new flexible materials for 3D printing allow the substitution of po...
Microfluidic chips—in which chemical or biological fluid samples are mixed into linear or nonlinear concentration distribution profiles—have generated enormous enthusiasm of their ability to develop patterns for drug release and their pot...
A novel microfluidic flow rate detection method based on surface plasmon resonance (SPR) temperature imaging is proposed. The measurement is performed by space-resolved SPR imaging of the flow induced temperature variations. Theoretical simulations a...
Fast, efficient and more importantly accurate serial dilution is a necessary requirement for most biochemical microfluidic-based quantitative diagnostic applications. Over the last two decades, a multitude of microfluidic devices has been proposed, e...
Magnetic hybrid hydrogels have exhibited remarkable efficacy in various areas, particularly in the biomedical sciences, where these inventive substances exhibit intriguing prospects for controlled drug delivery, tissue engineering, magnetic separatio...
The dye-sensitized solar cells microfluidically integrated with a redox flow battery (µDSSC-RFB) belong to a new emerging class of green energy sources with an inherent opportunity for energy storage. The successful engineering of microfluidica...
Blood cell manipulation in microdevices is an interesting task for the separation of particles, by their size, density, or to remove them from the buffer, in which they are suspended, for further analysis, and more. This study highlights the cell-fre...
The development of new standardized test methods would allow for the consistent evaluation of microfluidic medical devices and enable high-quality products to reach the market faster. A comprehensive flow characterization study was conducted to ident...
Techniques, such as micropipette aspiration and optical tweezers, are widely used to measure cell mechanical properties, but are generally labor-intensive and time-consuming, typically involving a difficult process of manipulation. In the past two de...
Separating the particles from the liquid component of sample solutions is important for several microfluidic-based sample preparations and/or sample handling techniques, such as plasma separation from whole blood, sheath-free flow focusing, particle...
Food allergies are a severe burden for affected individuals and healthcare systems. To tackle the need for simple food allergen detection, we developed a system for the detection of the soy protein glycinin via a centrifugal microfluidics-assisted la...
The demand for highly controllable droplet generation methods is very urgent in the medical, materials, and food industries. The droplet generation in a flow-focusing microfluidic device with external mechanical vibration, as a controllable droplet g...
Continuous-flow PCR (CF-PCR) can realize rapid DNA amplification because of the high temperature variation rate. However, off-line detection methods for PCR may induce cross contamination. To overcome this problem, we herein fabricated an integrated...
Diatom frustules are a type of natural biomaterials that feature regular shape and intricate hierarchical micro/nano structures. They have shown excellent performance in biosensing, yet few studies have been performed on flow-through detection. In th...
Droplet microfluidics is an extremely useful and powerful tool for industrial, environmental, and biotechnological applications, due to advantages such as the small volume of reagents required, ultrahigh-throughput, precise control, and independent m...
Gelatine methacryloyl (GM) shows high biocompatibility and is extensively used in tissue engineering; however, few works have explored the use of GM in bioactive agent delivery. This study adopts a microfluidic approach involving the use of flow-focu...
Biosensors are favored devices for the fast and cost-effective detection of biological species without the need for laboratories. Microfluidic integration with biosensors has advanced their capabilities in selectivity, sensitivity, controllability, a...
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