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5,683 Results Found

  • Article
  • Open Access
12 Citations
4,897 Views
24 Pages

12 December 2020

In capital-intensive industries, physical assets and maintenance activities play a relevant and strategic role in terms of providing operational continuity and business sustainability. As a result, maintenance support structures are highly complex an...

(This article belongs to the Special Issue Mathematical Methods and Analysis for the Industrial Management and Business)
  • Article
  • Open Access
11 Citations
2,620 Views
19 Pages

15 March 2023

This paper investigates single-machine scheduling with a deteriorating maintenance activity, where the processing time of a job depends on whether it is handled before or after the maintenance activity. Under common and slack due date assignments, th...

(This article belongs to the Special Issue Simplifying the Complex: Modeling and Analysis for System Design and Management)
  • Article
  • Open Access
5 Citations
1,686 Views
21 Pages

16 August 2023

In this paper, the single-machine scheduling problems under the common and slack due date assignments are studied, where the actual processing time of the job needs to consider some factors, such as convex resource allocation, maintenance activity, a...

(This article belongs to the Special Issue Systems Engineering, Control, and Automation)
  • Article
  • Open Access
398 Views
16 Pages

10 July 2026

Power grid maintenance tasks often involve sustained arm elevation, asymmetric upper-limb loading, and repetitive pulling, all of which may increase the risk of work-related musculoskeletal disorders. This study evaluated the effects of a passive upp...

(This article belongs to the Special Issue Human-Centered Design in Wearable Technology)
  • Article
  • Open Access
5 Citations
3,897 Views
27 Pages

The literature has not yet well documented the relative elements of the adoption of healthy lifestyle habits (HLHs) over the long term. More especially, researchers are calling to complete the corpus with qualitative or mixed estimates that would all...

(This article belongs to the Section Global Health)
  • Communication
  • Open Access
4 Citations
5,432 Views
10 Pages

18 December 2019

Maintaining weight loss is considerably more challenging than losing weight. Most previous studies on weight loss maintenance have been conducted in Western countries and have assessed physical activity and sleep with the use of questionnaires. This...

  • Article
  • Open Access
14 Citations
10,992 Views
22 Pages

Investigating Factors Affecting Behavioral Intention among Gym-Goers to Visit Fitness Centers during the COVID-19 Pandemic: Integrating Physical Activity Maintenance Theory and Social Cognitive Theory

  • Ardvin Kester S. Ong,
  • Yogi Tri Prasetyo,
  • Godwin M. Bagon,
  • Christian Hope S. Dadulo,
  • Nathaniel O. Hortillosa,
  • Morrissey A. Mercado,
  • Thanatorn Chuenyindee,
  • Reny Nadlifatin and
  • Satria Fadil Persada

23 September 2022

The COVID-19 pandemic has led to the closure of many fitness centers and has significantly affected the behavioral intentions of gym-goers. This study aimed to determine factors affecting the behavioral intentions of gym-goers regarding fitness cente...

(This article belongs to the Special Issue Sustainable Development and Management in Sports and Fitness Services during COVID-19 Pandemic)
  • Article
  • Open Access
5 Citations
3,535 Views
19 Pages

30 January 2025

Variable machine efficiency (VME) and maintenance activities (MA) are critical factors often unexplored in job scheduling problems. This paper introduces a new problem termed the job-shop scheduling problem with variable machine efficiency and mainte...

  • Article
  • Open Access
2 Citations
3,471 Views
16 Pages

An Integrated GIS Methodology to Assess the Impact of Engineering Maintenance Activities: A Case Study of Dredging Projects

  • Pedro Magaña,
  • Miguel Á. Reyes-Merlo,
  • Ángela Tintoré,
  • Carmen Zarzuelo and
  • Miguel Ortega-Sánchez

Engineering infrastructures require regular maintenance and/or repair activities that have important social, environmental, and economic impacts. Despite their growing importance, few studies have focused on fully integrated analyses. This work prese...

(This article belongs to the Special Issue Coastal and Marine Geographic Information Systems)
  • Article
  • Open Access
4 Citations
3,679 Views
14 Pages

Maintenance of Physical Activity Behavior by Individuals with Prediabetes and Diabetes during the COVID-19 Pandemic after Completing an Exercise Intervention in Brazil

  • Isabela Coelho Ponciano,
  • Mariana Balbi Seixas,
  • Tiago Peçanha,
  • Adriano Luiz Pereira,
  • Patrícia Fernandes Trevizan,
  • Raquel Rodrigues Britto and
  • Lilian Pinto da Silva

This cross-sectional study evaluated the perception of individuals with prediabetes/diabetes about their living conditions during the COVID-19 pandemic to identify the facilitators, barriers, and reasons to remain physically active at home and adhere...

(This article belongs to the Section Health Behavior, Chronic Disease and Health Promotion)
  • Review
  • Open Access
20 Citations
4,584 Views
14 Pages

Hydrogen Peroxide Signaling in the Maintenance of Plant Root Apical Meristem Activity

  • Hui Liu,
  • Yangwei Mu,
  • Yuxin Xuan,
  • Xiaolin Wu,
  • Wei Wang and
  • Hui Zhang

Hydrogen peroxide (H2O2) is a prevalent reactive oxygen species (ROS) found in cells and takes a central role in plant development and stress adaptation. The root apical meristem (RAM) has evolved strong plasticity to adapt to complex and changing en...

(This article belongs to the Special Issue Reactive Oxygen and Nitrogen Species in Plants―2nd Edition)
  • Article
  • Open Access
36 Citations
9,795 Views
17 Pages

Anthocyanin degradation decreases ornamental or nutritional values of horticultural products. To investigate factors that may influence colour change in flower development, anthocyanin degradation was compared between the flowers of Brunfelsia calyci...

(This article belongs to the Special Issue Anthocyanins)
  • Article
  • Open Access
30 Citations
5,705 Views
18 Pages

8 January 2021

In industrial maintenance activity, very sophisticated technical and human factors are needed to achieve the great process or service that the company provides, with a large dose of knowledge based on the personal experience of maintenance technician...

(This article belongs to the Special Issue Digitalized Industrial Production Systems and Industry 4.0)
  • Review
  • Open Access
17 Citations
10,346 Views
28 Pages

Resveratrol and Physical Activity: A Successful Combination for the Maintenance of Health and Wellbeing?

  • Mario Ruggiero,
  • Maria Letizia Motti,
  • Rosaria Meccariello and
  • Filomena Mazzeo

28 February 2025

Physical exercise is an essential component of human health. In recent years, scientific research has focused on identifying natural compounds and formulating new supplements aimed at enhancing athletic performance, accelerating muscle recovery, and...

(This article belongs to the Section Micronutrients and Human Health)
  • Article
  • Open Access
1 Citations
2,550 Views
13 Pages

13 November 2025

Background: Young adults, particularly university students, are at increased risk for psychological distress and burnout. Regular physical activity is widely recognized as a protective factor for mental health. This study aimed to compare physically...

(This article belongs to the Section Mental Health and Psychosocial Well-being)
  • Article
  • Open Access
6 Citations
4,533 Views
20 Pages

Polymerase ζ Is Involved in Mitochondrial DNA Maintenance Processes in Concert with APE1 Activity

  • Heike Katrin Schreier,
  • Rahel Stefanie Wiehe,
  • Miria Ricchetti and
  • Lisa Wiesmüller

13 May 2022

Mitochondrial DNA (mtDNA) damaged by reactive oxygen species (ROS) triggers so far poorly understood processes of mtDNA maintenance that are coordinated by a complex interplay among DNA repair, DNA degradation, and DNA replication. This study was des...

(This article belongs to the Section Molecular Genetics and Genomics)
  • Article
  • Open Access
2,711 Views
14 Pages

21 December 2023

(1) Background: Labor market outcomes can be directly or indirectly influenced by the health behavior patterns of the labor force. This study assesses the association between patterns of physical activity and smoking behavior maintenance (and their t...

  • Communication
  • Open Access
29 Citations
9,222 Views
13 Pages

Dietary Protein and Physical Activity Interventions to Support Muscle Maintenance in End-Stage Renal Disease Patients on Hemodialysis

  • Floris K. Hendriks,
  • Joey S.J. Smeets,
  • Frank M. van der Sande,
  • Jeroen P. Kooman and
  • Luc J.C. van Loon

5 December 2019

End-stage renal disease patients have insufficient renal clearance capacity left to adequately excrete metabolic waste products. Hemodialysis (HD) is often employed to partially replace renal clearance in these patients. However, skeletal muscle mass...

(This article belongs to the Special Issue Nutrition for Musculoskeletal Health)
  • Abstract
  • Open Access
1,383 Views
2 Pages

Health App Use May Motivate the Maintenance of Physical Activity during Pregnancy

  • Ella Koivuniemi,
  • Monique M. Raats,
  • Helena Ollila,
  • Eliisa Löyttyniemi and
  • Kirsi Laitinen

Background and objectives: A health-promoting lifestyle during pregnancy is beneficial for both the mother and the child, but an increase in physical activity, eating a healthy diet and achieving the recommended weight gain require high motivation. H...

(This article belongs to the Proceedings of The 14th European Nutrition Conference FENS 2023)
  • Article
  • Open Access
2,454 Views
26 Pages

23 January 2024

Maintenance of brain structure is essential for neurocognitive health. Precision medicine has interests in understanding how maintenance of an individual person’s brain, including cerebral cortical structure, interacts with lifestyle factors li...

(This article belongs to the Section Methodology, Drug and Device Discovery)
  • Article
  • Open Access
3 Citations
3,102 Views
16 Pages

Perspectives on Ease of Use and Value of a Self-Monitoring Application to Support Physical Activity Maintenance among Individuals Living with and beyond Cancer

  • Manuel Ester,
  • Meghan H. McDonough,
  • Mannat Bansal,
  • Julianna Dreger,
  • Julia T. Daun,
  • Margaret L. McNeely,
  • Thompson Luu and
  • S. Nicole Culos-Reed

19 March 2024

Background: Physical activity (PA) can improve the physical and psychosocial health of individuals with cancer, yet PA levels remain low. Technology may address PA maintenance barriers in oncology, though the intervention effectiveness to date remain...

(This article belongs to the Special Issue Optimizing Integrated Cancer Care from Diagnosis to Survivorship)
  • Article
  • Open Access
13 Citations
5,750 Views
18 Pages

Hair Maintenance and Chemical Hair Product Usage as Barriers to Physical Activity in Childhood and Adulthood among African American Women

  • Symielle A. Gaston,
  • Tamarra James-Todd,
  • Nyree M. Riley,
  • Micaela N. Gladney,
  • Quaker E. Harmon,
  • Donna D. Baird and
  • Chandra L. Jackson

Qualitative studies have identified haircare practices as important culturally specific barriers to physical activity (PA) among Black/African American (AA) women, but quantitative investigations are lacking. Using the Study of Environment, Lifestyle...

(This article belongs to the Special Issue Physical Fitness and Health Improvement)
  • Article
  • Open Access
18 Citations
7,280 Views
26 Pages

21 December 2021

Major overhauls, outages, shutdowns and turnarounds (MoOSTs) are significant maintenance interventions needed on a periodic basis to optimise the performance of physical industrial assets (PIAs). However, uncertainties in the forms of emergent and di...

(This article belongs to the Special Issue Sustainability in Operations Management)
  • Article
  • Open Access
2 Citations
1,848 Views
19 Pages

Effects of Industrial Maintenance Task Complexity on Neck and Shoulder Muscle Activity During Augmented Reality Interactions

  • Mohammed H. Alhaag,
  • Faisal M. Alessa,
  • Ibrahim M. Al-harkan,
  • Mustafa M. Nasr,
  • Mohamed Z. Ramadan and
  • Saleem S. AlSaleem

25 November 2024

Extensive studies have demonstrated the advantages of augmented reality (AR) in improving efficiency, thereby fulfilling a quality role in industry. Yet, the corresponding physical strain on individuals poses a significant challenge. This study explo...

(This article belongs to the Special Issue Applications of Virtual, Augmented and Mixed Reality)
  • Article
  • Open Access
23 Citations
8,348 Views
15 Pages

Contribution of Intrinsic Lactate to Maintenance of Seizure Activity in Neocortical Slices from Patients with Temporal Lobe Epilepsy and in Rat Entorhinal Cortex

  • Eskedar Ayele Angamo,
  • Rizwan Ul Haq,
  • Jörg Rösner,
  • Siegrun Gabriel,
  • Zoltán Gerevich,
  • Uwe Heinemann and
  • Richard Kovács

Neuronal lactate uptake supports energy metabolism associated with synaptic signaling and recovery of extracellular ion gradients following neuronal activation. Altered expression of the monocarboxylate transporters (MCT) in temporal lobe epilepsy (T...

(This article belongs to the Special Issue Commemorative Issue in Honor of Professor Uwe Heinemann: Metabolic Epilepsies)
  • Article
  • Open Access
9 Citations
3,475 Views
20 Pages

Leveraging Active Learning for Failure Mode Acquisition

  • Amol Kulkarni,
  • Janis Terpenny and
  • Vittaldas Prabhu

4 March 2023

Identifying failure modes is an important task to improve the design and reliability of a product and can also serve as a key input in sensor selection for predictive maintenance. Failure mode acquisition typically relies on experts or simulations wh...

(This article belongs to the Special Issue Sensors for Machine Condition Monitoring, Diagnostics, Prognostics and Maintenance)
  • Article
  • Open Access
14 Citations
4,012 Views
20 Pages

Stearoyl-CoA Desaturase 1 Activity Determines the Maintenance of DNMT1-Mediated DNA Methylation Patterns in Pancreatic β-Cells

  • Aneta M. Dobosz,
  • Justyna Janikiewicz,
  • Anna M. Borkowska,
  • Anna Dziewulska,
  • Ewelina Lipiec,
  • Pawel Dobrzyn,
  • Wojciech M. Kwiatek and
  • Agnieszka Dobrzyn

18 September 2020

Metabolic stress, such as lipotoxicity, affects the DNA methylation profile in pancreatic β-cells and thus contributes to β-cell failure and the progression of type 2 diabetes (T2D). Stearoyl-CoA desaturase 1 (SCD1) is a rate-limiting enzym...

(This article belongs to the Special Issue CoA in Health and Disease)
  • Article
  • Open Access
9 Citations
2,981 Views
22 Pages

Design of Sensorized Rail Pads for Real-Time Monitoring and Predictive Maintenance of Railway Infrastructure

  • Amparo Guillén,
  • Oswaldo Guerrero-Bustamante,
  • Guillermo R. Iglesias,
  • Fernando Moreno-Navarro and
  • Miguel Sol-Sánchez

Embedding sensors in rail pads allows for direct monitoring of train–track interaction, which is essential for preventive maintenance and sustainable management of railway infrastructure. Nonetheless, given the critical role that rail pads play...

  • Article
  • Open Access
9 Citations
3,916 Views
15 Pages

11 January 2025

The strategic optimization of a container terminal’s quayside assets, including the berth and quay cranes, is crucial for maximizing their deployment and utilization. The interrelated and complex challenges of Berth Allocation (BAP) and Quay Cr...

(This article belongs to the Special Issue Future Transportation Systems: Efficiency and Reliability)
  • Article
  • Open Access
8 Citations
4,356 Views
30 Pages

A Novel Handrub Tablet Loaded with Pre- and Post-Biotic Solid Lipid Nanoparticles Combining Virucidal Activity and Maintenance of the Skin Barrier and Microbiome

  • Ana Carolina Henriques Ribeiro Machado,
  • Laís Júlio Marinheiro,
  • Heather Ann Elizabeth Benson,
  • Jeffrey Ernest Grice,
  • Tereza da Silva Martins,
  • Alexandra Lan,
  • Patricia Santos Lopes,
  • Newton Andreo-Filho and
  • Vania Rodrigues Leite-Silva

Objective: This study aimed to develop a holobiont tablet with rapid dispersibility to provide regulation of the microbiota, virucidal activity, and skin barrier protection. Methods: A 23 factorial experiment was planned to define the best formulatio...

(This article belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
  • Review
  • Open Access
55 Citations
17,774 Views
14 Pages

Physical Activity and Nutrition: Two Promising Strategies for Telomere Maintenance?

  • Estelle Balan,
  • Anabelle Decottignies and
  • Louise Deldicque

7 December 2018

As the world demographic structure is getting older, highlighting strategies to counteract age-related diseases is a major public health concern. Telomeres are nucleoprotein structures that serve as guardians of genome stability by ensuring protectio...

(This article belongs to the Special Issue Integrated Role of Nutrition and Physical Activity for Lifelong Health)
  • Review
  • Open Access
672 Views
48 Pages

Lifestyle Medicine as Co-Therapy During Incretin-Based Anti-Obesity Pharmacotherapy: Integrating Physical Activity, Nutrition, and Behavioral Strategies for Long-Term Success

  • Marta Mallardo,
  • Antonietta Messina,
  • Vincenzo Monda,
  • Marco La Marra,
  • Antonietta Monda,
  • Salvatore Allocca,
  • Maria Casillo,
  • Girolamo Di Maio,
  • Pasquale Perrone and
  • Rita Polito
  • + 4 authors

22 August 2026

Background/Objectives: Obesity is a chronic, progressive, and relapsing disease that requires long-term, multidisciplinary management rather than episodic weight-loss treatment. Although novel incretin-based anti-obesity pharmacotherapies, including...

(This article belongs to the Section Nutrition and Obesity)
  • Proceeding Paper
  • Open Access
924 Views
7 Pages

Lifestyle behaviors such as diet and physical activity are central to healthy aging, yet their temporal organization remains underexplored in aging research. Drawing on concepts from sports science, this perspective proposes a conceptual framework ex...

(This article belongs to the Proceedings of The 5th International Online Conference on Nutrients)
  • Article
  • Open Access
1 Citations
2,700 Views
21 Pages

9 April 2022

The article covers issues related to the selection of a management strategy for the operation of technical infrastructure. It contains the approaches, methodology and a general model of the system of operation of the Maintenance Services of the LOTOS...

(This article belongs to the Section Sustainable Urban and Rural Development)
  • Article
  • Open Access
1 Citations
2,836 Views
17 Pages

22 March 2023

Active optics and aberration correction techniques for sparse aperture segmented mirrors are studied. A finite element model of the sparse aperture segmented mirror was established, and a multi-aperture aberration polynomial was derived. According to...

  • Article
  • Open Access
1,241 Views
14 Pages

Standard predictive equations for maintenance energy requirements often do not account for individual variability in dogs, potentially leading to nutritional inaccuracies. This prospective proofofconcept study evaluated a dynamic energy prescription...

(This article belongs to the Section Nutritional and Metabolic Diseases in Veterinary Medicine)
  • Review
  • Open Access
11 Citations
5,456 Views
28 Pages

Telomere Maintenance and DNA Repair: A Bidirectional Relationship in Cancer Biology and Therapy

  • Nina Rembiałkowska,
  • Mikołaj Sędzik,
  • Monika Kisielewska,
  • Wiktoria Łuniewska,
  • Kamil Sebastianka,
  • Klaudia Molik,
  • Katarzyna Skinderowicz,
  • Jacek Kuźnicki,
  • Joanna Tunikowska and
  • Julita Kulbacka

9 July 2025

Telomeres are repetitive DNA sequences at the ends of chromosomes that protect against genomic instability and prevent unwanted DNA damage responses. In most somatic cells, telomeres progressively shorten with each division, limiting cellular lifespa...

(This article belongs to the Section Molecular Cancer Biology)
  • Review
  • Open Access
9 Citations
6,177 Views
28 Pages

Comprehensive Review of Biological Functions and Therapeutic Potential of Perilla Seed Meal Proteins and Peptides

  • Yangfan Hu,
  • Huan Luo,
  • Vasudeva Reddy Netala,
  • He Li,
  • Zhijun Zhang and
  • Tianyu Hou

27 December 2024

This comprehensive review explores the biological functions of Perilla frutescens seed proteins and peptides, highlighting their significant potential for health and therapeutic applications. This review delves into the mechanisms through which peril...

(This article belongs to the Section Food Biotechnology)
  • Article
  • Open Access
19 Citations
5,290 Views

7 November 2018

A data mining approach is integrated in this work for predictive sequential maintenance along with information on spare parts based on the history of the maintenance data. For most practical problems, the simple failure of one part of a given piece o...

  • Article
  • Open Access
14 Citations
4,067 Views
19 Pages

A Multi-Endpoint Approach to Base Excision Repair Incision Activity Augmented by PARylation and DNA Damage Levels in Mice: Impact of Sex and Age

  • Nicola Winkelbeiner,
  • Viktoria K. Wandt,
  • Franziska Ebert,
  • Kristina Lossow,
  • Ezgi E. Bankoglu,
  • Maximilian Martin,
  • Aswin Mangerich,
  • Helga Stopper,
  • Julia Bornhorst and
  • Tanja Schwerdtle
  • + 1 author

9 September 2020

Investigation of processes that contribute to the maintenance of genomic stability is one crucial factor in the attempt to understand mechanisms that facilitate ageing. The DNA damage response (DDR) and DNA repair mechanisms are crucial to safeguard...

(This article belongs to the Section Molecular Biology)
  • Article
  • Open Access
15 Citations
3,564 Views
19 Pages

This study proposed a data mining framework for predicting sequential patterns of maintenance activities. The framework consisted of data collection, prediction of maintenance activities with and without attributes, and then the comparison between pr...

(This article belongs to the Special Issue Computational Approach Applications in Housing and Real Estate)
  • Article
  • Open Access
1 Citations
5,200 Views
22 Pages

A Method to Account for Personnel Risk Attitudes in System Design and Maintenance Activity Development

  • Benjamin W. Rathwell,
  • Douglas L. Van Bossuyt,
  • Anthony Pollman and
  • Joseph Sweeney

4 August 2020

Systems engineering practices in the maritime industry and the Navy consider operational availability as a system attribute determined by system components and a maintenance concept. A better understanding of the risk attitudes of system operators an...

(This article belongs to the Section Systems Engineering)
  • Article
  • Open Access
4 Citations
3,166 Views
21 Pages

StaR Is a Positive Regulator of Topoisomerase I Activity Involved in Supercoiling Maintenance in Streptococcus pneumoniae

  • Antonio A. de Vasconcelos Junior,
  • Jose M. Tirado-Vélez,
  • Antonio J. Martín-Galiano,
  • Diego Megias,
  • María-José Ferrándiz,
  • Pablo Hernández,
  • Mónica Amblar and
  • Adela G. de la Campa

The DNA topoisomerases gyrase and topoisomerase I as well as the nucleoid-associated protein HU maintain supercoiling levels in Streptococcus pneumoniae, a main human pathogen. Here, we characterized, for the first time, a topoisomerase I regulator p...

(This article belongs to the Special Issue Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases)
  • Article
  • Open Access
8 Citations
3,183 Views
14 Pages

Use of Simulation Tools for Optimization of the Time Duration of Winter Maintenance Activities at Airports

  • Hana Pačaiová,
  • Peter Korba,
  • Michal Hovanec,
  • Jozef Galanda,
  • Patrik Šváb and
  • Ján Lukáč

21 January 2021

Aviation and climate change are often associated. The effects of climate change have increasing impact on the safe operation of airports. Due to both climate and weather conditions changes, airport winter maintenance is a significantly important acti...

(This article belongs to the Section Sustainable Transportation)
  • Review
  • Open Access
2,554 Views
17 Pages

The Endothelial Centrosome: Specific Features and Functional Significance for Endothelial Cell Activity and Barrier Maintenance

  • Anton Sergeevich Shakhov,
  • Aleksandra Sergeevna Churkina,
  • Anatoly Alekseevich Kotlobay and
  • Irina Borisovna Alieva

20 October 2023

This review summarizes information about the specific features that are characteristic of the centrosome and its relationship with the cell function of highly specialized cells, such as endotheliocytes. It is based on data from other researchers and...

(This article belongs to the Section Molecular Biology)
  • Article
  • Open Access
17 Citations
6,024 Views
19 Pages

26 August 2021

Correlative studies of clinical studies for hematological malignancies have implicated that less differentiated, CD8+-dominant CAR T cell products have greater antitumor activity. Here, we have investigated whether the differentiation status of CAR T...

(This article belongs to the Collection Mechanism of Immunotherapy in Cancers)
  • Article
  • Open Access
1 Citations
2,608 Views
14 Pages

Possible Involvement of the Upregulation of ΔNp63 Expression Mediated by HER2-Activated Aryl Hydrocarbon Receptor in Mammosphere Maintenance

  • Yuichiro Kanno,
  • Nao Saito,
  • Naoya Yamashita,
  • Kazuki Ota,
  • Ryota Shizu,
  • Takuomi Hosaka,
  • Kiyomitsu Nemoto and
  • Kouichi Yoshinari

11 October 2022

Cancer stem cells (CSCs) contribute to the drug resistance, recurrence, and metastasis of breast cancers. Recently, we demonstrated that HER2 overexpression increases mammosphere formation via the activation of aryl hydrocarbon receptor (AHR). In thi...

(This article belongs to the Section Molecular Biology)
  • Article
  • Open Access
2 Citations
5,566 Views
20 Pages

SYNTAXIN OF PLANTS132 Regulates Root Meristem Activity and Stem Cell Niche Maintenance via RGF-PLT Pathways

  • Mingjing Wang,
  • Fumeng He,
  • Wei Zhang,
  • Chong Du,
  • Linlin Wang,
  • Jia Sui and
  • Fenglan Li

27 February 2025

Root growth and development are contingent upon continuous cell division and differentiation in root tips. In this study, we found that the knockdown of the syntaxin gene SYNTAXIN OF PLANTS132 (SYP132) in Arabidopsis thaliana resulted in a significan...

(This article belongs to the Section Molecular Plant Sciences)
  • Article
  • Open Access
12 Citations
4,088 Views
17 Pages

Of the Mechanisms of Paroxysmal Depolarization Shifts: Generation and Maintenance of Bicuculline-Induced Paroxysmal Activity in Rat Hippocampal Cell Cultures

  • Denis P. Laryushkin,
  • Sergei A. Maiorov,
  • Valery P. Zinchenko,
  • Valentina N. Mal’tseva,
  • Sergei G. Gaidin and
  • Artem M. Kosenkov

Abnormal depolarization of neuronal membranes called paroxysmal depolarization shift (PDS) represents a cellular correlate of interictal spikes. The mechanisms underlying the generation of PDSs or PDS clusters remain obscure. This study aimed to inve...

(This article belongs to the Special Issue Molecular and Cellular Mechanisms of Epilepsy 2.0)
  • Article
  • Open Access
30 Citations
4,648 Views
21 Pages

21 April 2021

Maintenance experts involved in managing major maintenance activities such as; Major overhauls, outages, shutdowns and turnarounds (MoOSTs) are constantly faced with uncertainties during the planning and/or execution phases, which often stretches bey...

(This article belongs to the Special Issue Sustainability in Operations Management)

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