CNC machining is a high precision computer-controlled subtractive manufacturing technique. In this paper, motor selection for a custom-made, low-cost, multi-axis CNC machine is discussed. The paper also deals with mechanical assembly of the custom-ma...
Hyperspectral microscope imaging (HMI) is an emerging modality that integrates spatial information collected by standard laboratory microscopy and the spectral-based contrast obtained by hyperspectral imaging and may be instrumental in establishing n...
Bone can be affected by different neoplastic conditions. Limb salvage surgery has become the preferred treatment strategy for most malignant tumors of the extremities. Advanced 3D printing technology has transformed the conventional view of oncologic...
The purpose of the current investigation was to evaluate the clinical success of horizontal ridge augmentation in severely atrophic maxilla (Cawood and Howell class IV) using freeze-dried custom made bone harvested from the tibial hemiplateau of cada...
14 May 2022
Study design: Retrospective case series. Objective: Alloplastic temporomandibular joint replacement has been established as a standard technique for end- stage temporomandibular (TMJ) pathologies. Joint replacement when there are extensive mandibular...
Background: Custom-made subperiosteal implants have re-emerged as a valuable option for the rehabilitation of patients with severe maxillofacial atrophy and post-oncological defects. Despite advances in digital workflows and implant design, their uni...
In this study, a new methodology for designing and creating a custom-made template for maxillofacial surgery has been developed. The custom-made template can be used both for cutting and repositioning of the mandible arches for executing a BSSO (bila...
31 March 2016
The use of virtual surgical planning and computer-aided design/computer-aided manufacturing has been reported to enhance the planning for the reconstruction of mandibular continuity defects. This case report illustrates the use of this technology in...
Hyperspectral imaging (HSI) is a promising optical modality that is already being used in numerous applications. Further expansion of the capabilities of HSI depends on the modularity and versatility of the systems, which would, inter alia, incorpora...
Background and Objectives: Alveolar ridge augmentation in the complex bone defect is a popular topic in implantology. Guided bone regeneration (GBR) is one of the most commonly applied methods to reconstruct alveolar bone. The application of a membra...
To reduce the trial and error in a real clinical scenario, the finite element analysis (FEA) can be effectively used to simulate various effective pad designs and a material selection to reduce and redistribute peak plantar pressure in a diabetic foo...
In orthopaedic oncology, limb salvage procedures are becoming more frequent thanks to recent major improvements in medical imaging, biomechanical modelling and additive manufacturing. For the pelvis, surgical reconstruction with metal implants after...
Objectives: Cleaning splints (CSs) can facilitate interdental brush (IDB) insertion and guide IDBs during cleaning movement. Cleaning efficacy with and without CSs was to be assessed and compared for a fully dentate (FD) and a partially edentulous (P...
Stroke often causes neuromotor disabilities, impacting index finger function in daily activities. Due to the role of repetitive, even passive, finger movements in neuromuscular re-education and spasticity control, this study aims to design a rehabili...
G-protein coupled receptors (GPCRs) are known for their low stability and large conformational changes upon transitions between multiple states. A widely used method for stabilizing these receptors is to make chimeric receptors by fusing soluble prot...
In severe cases of total knee arthroplasty, where off-the-shelf implants are not suitable or available anymore (i.e., in cases with extended bone defects or periprosthetic fractures), custom-made knee implants represent one of the few remaining treat...
When fabricating custom-made mouthguards for children, tooth replacement is an important factor for dentists to consider. In addition, orofacial myofunctional disorders and deleterious oral habits—such as incompetent lip seal and tongue thrusti...
The success of dental implant placement and prosthetic reconstruction relies on sufficient bone volume at the implant site. Contemporary implantology integrates prosthetic planning with implant placement, emphasizing the importance of pre-established...
Background: Severe glenoid bone loss presents a major challenge in both primary and revision reverse shoulder arthroplasty (RSA). Standard implants often fail to achieve reliable fixation in these cases. Custom-made, 3D-printed glenoid components hav...
Sports-related oro-dento-facial trauma is a major clinical and socioeconomic burden, with oro-dento-facial injuries affecting approximately 30–40% of athletes. Mouthguards are widely recommended as primary protective devices, yet the comparativ...
This clinical report demonstrated the use of polyetheretherketone (PEEK) for manufacturing of custom-made post and core in weakened endodontically treated central incisors. The PEEK structure was manufactured using computer-aided design/computer-aide...
Background: Nowadays, a combination of classical subperiosteal implant designs with 3D imaging and printing allows one to reduce treatment time and provides support for fixed prostheses in cases where other techniques do not provide satisfactory resu...
Background and Objectives: Reconstruction of extensive acetabular bone defects in revision total hip arthroplasty (THA) remains technically demanding and is associated with a high risk of complications. Custom-made three-dimensional (3D)-printed impl...
22 September 2021
Background: This report discusses the utility of a wearable augmented reality platform in neurosurgery for parasagittal and convexity en plaque meningiomas with bone flap removal and custom-made cranioplasty. Methods: A real patient with en plaque cr...
This work presents the application of an aerial manipulation robot for the semi-autonomous installation of clip-type bird flight diverters on overhead power line cables. A custom-made prototype is designed, developed, and experimentally validated. Th...
Restoring deep, extensive carious lesions and subgingival situations can be challenging due to difficulties in placing matrices and achieving isolation. This article describes a technique utilizing individually designed digital matrices for challengi...
In orthopedic oncology, revisional surgery due to mechanical failure or local recurrence is not uncommon following limb salvage surgery using an endoprosthesis. However, due to the lack of clinical experience in limb salvage surgery using 3D-printed...
The presence of non-sufficient bone height and width requires an increase in the amount of bone available to insert an implant. Different materials are described in the literature, and the “custom-made bone graft approach” is a modern opt...
This article presents the process of development, testing, and use of wrist–hand orthosis in the hand therapy of a teen patient with congenital paresis disease. A regular 3D-printed anatomically adjusted orthosis is modified with a set of senso...
The study of CAD (computer aided design) modeling, design and manufacturing techniques has undergone a rapid growth over the past decades. In medicine, this development mainly concerned the dental and maxillofacial sectors. Significant progress has a...
Detecting stress when performing physical activities is an interesting field that has received relatively little research interest to date. In this paper, we took a first step towards redressing this, through a comprehensive review and the design of...
Custom-made, three-dimensionally-printed (3D) bone prostheses gain increasing importance in the reconstruction of bone defects after musculoskeletal tumor resections. They may allow preservation of little remaining bone stock and ensure joint or limb...
Bone tumors of the upper limb are a common cause of bone pain and pathological fractures in both old and young populations. Surgical reconstruction and limb salvage have become valid options for these patients despite this kind of surgery being chall...
Metal-on-metal bearings for total hip replacements have been introduced as an alternative to polyethylene in young and more active patients. These have, however, been shown to be prone to implant malpositioning and have been limited by some specific...
Background/Objectives: Severe acetabular bone loss, particularly Paprosky type IIIA and IIIB defects and pelvic discontinuity, represents a major challenge in revision total hip arthroplasty (rTHA). Custom-made acetabular implants offer a patient-spe...
Custom-made orthotic insoles are routinely used in the treatment of the diabetic foot to reduce plantar pressure so as to minimise the risk of neuropathic ulceration. Due to the 3D geometry shape of the foot and insole, the measurement of the foot-or...
Robotic hands with unique designs, capabilities and applications have been presented in the literature focusing on sensing, actuation, control, powering and manufacturing, most of which are created by manual assembly process. However, due to advancem...
This paper describes the development process of the quadcopter-based unmanned flying platform, designed for testing and experimentation purposes. The project features custom-made hardware, which includes the prototype quadcopter frame and the flight...
Background/Objectives: Post-traumatic nasal pyramid reconstruction is challenging in patients with severe deformity and exhausted autologous graft options, particularly after multiple failed surgeries. Custom-made titanium implants may offer precise...
The replication method is a widely used technique to produce bioactive glass (BG) scaffolds mimicking trabecular bone. However, these scaffolds usually exhibit poor mechanical reliability and fast degradation, which can be improved by coating them wi...
Every year, thousands of aortic valve replacements must take place due to valve diseases. Tissue-engineered heart valves represent promising valve substitutes with remodeling, regeneration, and growth capabilities. However, the accurate reproduction...
The present short communication described a new procedure for the reconstruction of the horizontal severely resorbed edentulous maxilla with custom-made deproteinized bovine bone block, fabricated using three-dimensional imaging of the patient and co...
Metagenomics analysis revealing the composition and functional repertoire of complex microbial communities typically relies on large amounts of sequence data. Numerous analysis strategies and computational tools are available for their analysis. Full...
In the framework of ISOL (isotope separation on-line) facilities, porous carbides are among the most employed target materials for the production of radioactive ion beams for research. As foreseen by the ISOL technique, a production target is impinge...
The rate at which oral tobacco-derived nicotine (OTDN) and snus pouches release nicotine into saliva is crucial to determine product performance. As no standardized method is available for this purpose, this study sought to develop a biorelevant diss...
This study investigated polymerization kinetics, linear shrinkage, and shrinkage stress development for six contemporary composite materials of different viscosities cured using radiant exitances of 1100–2850 mW/cm2. Real-time measurements of d...
Phononic crystals are a kind of artificial acoustic metamaterial whose mass density and elastic modulus are periodically arranged. The precise and efficient design of phononic crystals with specific bandgap characteristics has attracted increasing at...
Crosstalk between glomerular endothelial cells and glomerular epithelial cells (podocytes) is increasingly becoming apparent as a crucial mechanism to maintain the integrity of the glomerular filtration barrier. However, in vitro studies directly inv...
In this paper we demonstrate the fabrication and electrochemical characterization of a microchip with 12 identical but individually addressable electrochemical measuring sites, each consisting of a set of interdigitated electrodes acting as a working...
Background/Objectives: Oral appliance (OA) therapy is an established treatment option for patients with mild-to-moderate obstructive sleep apnea (OSA). Although OAs of various designs have been developed, clinical evidence regarding the effectiveness...
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