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Current Oncology
Volume 29
Issue 7
10.3390/curroncol29070361
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Article

Three-Dimension-Printed Custom-Made Prosthetic Reconstructions in Bone Tumors: A Single Center Experience

by
Raffaele Vitiello
1,2,
Maria Rosaria Matrangolo
1,2,
Alessandro El Motassime
1,2,*,
Andrea Perna
1,2,
Luigi Cianni
1,2,
Giulio Maccauro
1,2 and
Antonio Ziranu
1,2
1
Orthopedics & Traumatology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, 00168 Roma, Italy
2
Orthopedics and Traumatology, Università Cattolica Del Sacro Cuore, 00168 Roma, Italy
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2022, 29(7), 4566-4577; https://doi.org/10.3390/curroncol29070361
Submission received: 22 April 2022 / Revised: 19 June 2022 / Accepted: 24 June 2022 / Published: 28 June 2022
(This article belongs to the Section Bone and Soft Tissue Oncology)
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Abstract

Bone can be affected by different neoplastic conditions. Limb salvage surgery has become the preferred treatment strategy for most malignant tumors of the extremities. Advanced 3D printing technology has transformed the conventional view of oncological surgery. These types of implants are produced by electron beam melting (EBM) technology by sintering titanium powder in a scaffold shape designed following a project designed from HRCT and MRI. The aim of our study was to evaluate the outcomes and the mid-term follow-up of a population treated with 3D-printed custom-made prosthesis implantation in major oncological bone resection or after failure of primary implants. The primary outcome was the general patient satisfaction one year after surgery. The secondary outcomes were: mortality rate, treatment related complication rate, functional and clinical outcomes (KPS, ADL and IADL). Eight patients were included, five females and two males, with a mean age of 50.3 (±23.72) years at the surgery. The enrolled patients reported a mean satisfaction rate after surgery of 7.38 (±2) where 10 was the maximum value. There were no changes between pre- and postoperative mean KPS (81.43 +/−10.69). Mean preoperative ADL and IADL score was in both cases 4.86 (±1.07), while postoperative was 5 (±0.82), with a delta of 0.13 (p > 0.05). Custom-made prosthesis permits reconstructing bone defects caused by large tumor resection, especially in anatomically complex areas, restoring articular function.
Keywords: bone tumors; computer-aided design; 3D-printed prosthesis; reconstruction surgery; custom-made prosthesis; large bone defects bone tumors; computer-aided design; 3D-printed prosthesis; reconstruction surgery; custom-made prosthesis; large bone defects

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MDPI and ACS Style

Vitiello, R.; Matrangolo, M.R.; El Motassime, A.; Perna, A.; Cianni, L.; Maccauro, G.; Ziranu, A. Three-Dimension-Printed Custom-Made Prosthetic Reconstructions in Bone Tumors: A Single Center Experience. Curr. Oncol. 2022, 29, 4566-4577. https://doi.org/10.3390/curroncol29070361

AMA Style

Vitiello R, Matrangolo MR, El Motassime A, Perna A, Cianni L, Maccauro G, Ziranu A. Three-Dimension-Printed Custom-Made Prosthetic Reconstructions in Bone Tumors: A Single Center Experience. Current Oncology. 2022; 29(7):4566-4577. https://doi.org/10.3390/curroncol29070361

Chicago/Turabian Style

Vitiello, Raffaele, Maria Rosaria Matrangolo, Alessandro El Motassime, Andrea Perna, Luigi Cianni, Giulio Maccauro, and Antonio Ziranu. 2022. "Three-Dimension-Printed Custom-Made Prosthetic Reconstructions in Bone Tumors: A Single Center Experience" Current Oncology 29, no. 7: 4566-4577. https://doi.org/10.3390/curroncol29070361

APA Style

Vitiello, R., Matrangolo, M. R., El Motassime, A., Perna, A., Cianni, L., Maccauro, G., & Ziranu, A. (2022). Three-Dimension-Printed Custom-Made Prosthetic Reconstructions in Bone Tumors: A Single Center Experience. Current Oncology, 29(7), 4566-4577. https://doi.org/10.3390/curroncol29070361

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